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View Structure Prediction Details

Protein: gi|45552108, gi|...
Organism: Drosophila melanogaster
Length: 1483 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|45552108, gi|....

Description E-value Query
Range
Subject
Range
gi|114602280 - gi|114602280|ref|XP_001145015.1| PREDICTED: protocadherin beta 12 isoform 3 [Pan troglodytes]
734.0 [0..4] [676..120]

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Predicted Domain #1
Region A:
Residues: [1-645]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLISGSRLFS SSAPPLRLSR SYVSRVDENA PHGTALTFVD PYVPRVYDDD TGKNGVFSLT  60
   61 LLNNNGTFEI SPNVAERSAG FLIRVRDNSM LDYEQQQSVQ FQILAQELGP ATNLSALVNV 120
  121 TVYINDVNDN APVFEQPAYS VELPENMTAG TKVVQVLATD PDSGLGGKVR YTAILGYLNT 180
  181 SLNLDAETGL ITVSTNKHGF DREVMPEYHL YVEARDMDGE GNRAQVPLII KLIDVNDETP 240
  241 IFDKDLYEFI LTHDLMGFTT TAVIHAEDKD ATAPNNEVRY EIINGNYDNQ FVLDKVTGEL 300
  301 TVREKIHLRS KKNAKTRRRR QAGSDDEDTD IFILTARAYD LGVPVRFSTT TIRVYPPESR 360
  361 KRSVKFVVPG HNPDKAKTEE TLSALSGGKV YIHNIRPLSP DEPGAKDIPA GNPGIKERSV 420
  421 VTATVIYDSS SVVDISEIQQ RLSHHNNSYA IMPQDTSSTD TLTPLQTQYK AENKVLFWLL 480
  481 ILLATLVALT ILILLLCCIC SWCPLYGAAT KRIVNISRTE DDVHLVHREM ANGKQTKSVQ 540
  541 VAEWMGRRDA WSAEKPPDTR TKPTRWEFHD GREQLDEDVG RGQDIGEGDR RHIQSAEEQQ 600
  601 RRVRIKHNRT AKDDLHLNFH NSRTNLINDR DVYMEDVIEN RDLAG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 83.045757
Match: 1q55A
Description: W-shaped trans interactions of cadherins model based on fitting C-cadherin (1L3W) to 3D map of desmosomes obtained by electron tomography
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [646-815]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DREHITRTRV NRQEYARRKQ YDSEVRHIDD DSMRRHEIDR GSDIDFNTAH NSLKSKRELF  60
   61 IKDGNVEILQ LMTRDKTRDG LNLDDDNIYV NVPLKPAGNL SHPQLLMVDN TGKEILMRRF 120
  121 IEEQPDGKQI IREHYQIVPG ATYIQSMPNE VQQGSTLKGD TFPLGKSGPN 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [816-894]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SIVYSQLEPE VKVIHTQPVQ AGEGVSLDQQ MQPAVSNQSL THELEHSLKQ QNALLRQILM  60
   61 EKEKLENAYT QHEVALETQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [895-967]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SLPGQSMAIG TQTDCDAGTQ TEGFDGVLDP EISLAKPSRR RARSENDESM SEDGYEYVRF  60
   61 NPPNSPEGVY WIK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [968-1206]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RRRTKKRPRQ PRKRIVMVEE VKRKIRTPIK EEEEVQERKK RVPPKKPLRE TKTSILRKQL  60
   61 SDESRKDQSR NGESQTGNRH RSESDSHNRD MFMEITDSMD ELASPGSHSI RKIQVEKYYK 120
  121 HSDGDFDEDD TEYSIDSDGD EIVIRTNYPS RAQENERYRR QERTYAEPEN PVDRKRPARK 180
  181 SSPTDSQPEA MPRLSRRDSS KRGSRKQTSS EPPHNRVSIS KYESTVTENG RKLMSTSTE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [1207-1356]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IVGSKRSLTD RSYQSETELA GLEHEERNVP KYMEWYYNKK KSSVSGRTST ESSKSQPSSK  60
   61 KKVGAAEKRV SKTRITAQPK DVEEYDETGG RYKPEPAPRK SPPKGSRLLK EDRALNKQHK 120
  121 PKIETDTNHP LLQHSEHRFE RENALEVPAA 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [1357-1483]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTKLPHYMYP ETPPHAAAGG KESKSGRESK TSKEAKPKPS PIRENEVKVS NSKIYVEHRG  60
   61 TGHPTQKQLN ASTLEDDHDS GIAMNSLLNS LGRRNPIAEK KSVFSIAYDD VSRVKKINSG 120
  121 GESPQYS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle