YRC Public Data Repository - Protein Structure Prediction

Protein:	YBEA_ECOLI
Organism:	Escherichia coli
Length:	155 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YBEA_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|53732589 - gi\|53732589\|ref\|ZP_00154764.2\| COG1576: Uncharacterized conserved protein [Haemophilus influenzae R2... gi\|46133667 - gi\|46133667\|ref\|ZP_00157540.2\| COG1576: Uncharacterized conserved protein [Haemophilus influenzae R2... RLMH_HAEIN - Ribosomal RNA large subunit methyltransferase H OS=Haemophilus influenzae (strain ATCC 51907 / DSM 1... gi\|145641826, gi... - gi\|145641826\|ref\|ZP_01797401.1\| hypothetical protein CGSHiR3021_01112 [Haemophilus influenzae R3021]... RLMH_HAEIG - Ribosomal RNA large subunit methyltransferase H OS=Haemophilus influenzae (strain PittGG) GN=rlmH PE... gi\|145641826 - gi\|145641826\|ref\|ZP_01797401.1\| hypothetical protein CGSHiR3021_01112 [Haemophilus influenzae R3021] gi\|145639678, gi... - gi\|145639678\|ref\|ZP_01795281.1\| hypothetical protein CGSHiII_09181 [Haemophilus influenzae PittII], ... gi\|145629110, gi... - gi\|145629110\|ref\|ZP_01784909.1\| hypothetical protein CGSHi22121_09920 [Haemophilus influenzae 22.1-2... Y033_HAEIN, RLMH... - UPF0247 protein HI0033 OS=Haemophilus influenzae GN=HI0033 PE=3 SV=1, Ribosomal RNA large subunit me... gi\|229845379, gi... - gi\|229845379\|ref\|ZP_04465510.1\| hypothetical protein CGSHi6P18H1_00487 [Haemophilus influenzae 6P18H...	244.0	[0..1]	[155..1]
gi\|144985973, gi... - gi\|145633410\|ref\|ZP_01789140.1\| hypothetical protein CGSHi3655_04240 [Haemophilus influenzae 3655], ... RLMH_HAEI8 - Ribosomal RNA large subunit methyltransferase H OS=Haemophilus influenzae (strain 86-028NP) GN=rlmH ...	243.0	[0..1]	[155..1]
RLMH_SALPC - Ribosomal RNA large subunit methyltransferase H OS=Salmonella paratyphi C (strain RKS4594) GN=rlmH P... gi\|213999250 - gi\|213999250\|ref\|ZP_03409985.1\| SPOUT methyltransferase superfamily protein [Salmonella enterica sub... gi\|213857667 - gi\|213857667\|ref\|ZP_03384638.1\| SPOUT methyltransferase superfamily protein [Salmonella enterica sub... RLMH_SALPB - Ribosomal RNA large subunit methyltransferase H OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SP... gi\|238911591 - gi\|238911591\|ref\|ZP_04655428.1\| SPOUT methyltransferase superfamily protein [Salmonella enterica sub... RLMH_SALEP - Ribosomal RNA large subunit methyltransferase H OS=Salmonella enteritidis PT4 (strain P125109) GN=rl... RLMH_SALG2 - Ribosomal RNA large subunit methyltransferase H OS=Salmonella gallinarum (strain 287/91 / NCTC 13346... gi\|204930448, gi... - gi\|204930448\|ref\|ZP_03221378.1\| conserved hypothetical protein [Salmonella enterica subsp. enterica ... gi\|199602660, gi... - gi\|200390215\|ref\|ZP_03216826.1\| conserved hypothetical protein [Salmonella enterica subsp. enterica ... gi\|213649158 - gi\|213649158\|ref\|ZP_03379211.1\| SPOUT methyltransferase superfamily protein [Salmonella enterica sub... gi\|213580879 - gi\|213580879\|ref\|ZP_03362705.1\| SPOUT methyltransferase superfamily protein [Salmonella enterica sub... gi\|213425096 - gi\|213425096\|ref\|ZP_03357846.1\| SPOUT methyltransferase superfamily protein [Salmonella enterica sub... YBEA_SALPA, RLMH... - UPF0247 protein ybeA OS=Salmonella paratyphi A GN=ybeA PE=3 SV=1, Ribosomal RNA large subunit methyl... gi\|213160846 - gi\|213160846\|ref\|ZP_03346556.1\| SPOUT methyltransferase superfamily protein [Salmonella enterica sub... YBEA_SALTI - UPF0247 protein ybeA OS=Salmonella typhi GN=ybeA PE=3 SV=1 YBEA_SALTY - UPF0247 protein ybeA OS=Salmonella typhimurium GN=ybeA PE=3 SV=1 RLMH_SALTI - Ribosomal RNA large subunit methyltransferase H OS=Salmonella typhi GN=rlmH PE=3 SV=1 RLMH_SALTY - Ribosomal RNA large subunit methyltransferase H OS=Salmonella typhimurium GN=rlmH PE=3 SV=1 gi\|16759600 - gi\|16759600\|ref\|NP_455217.1\| SPOUT methyltransferase superfamily protein [Salmonella enterica subsp.... RLMH_SALTY - Ribosomal RNA large subunit methyltransferase H OS=Salmonella typhimurium (strain LT2 / SGSC1412 / A... YBEA_SALPB, RLMH... - UPF0247 protein ybeA OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=ybeA PE=3 SV=1, Ribo... gi\|29142627, gi\|... - gi\|29142627\|ref\|NP_805969.1\| SPOUT methyltransferase superfamily protein [Salmonella enterica subsp.... RLMH_SALAR - Ribosomal RNA large subunit methyltransferase H OS=Salmonella arizonae (strain ATCC BAA-731 / CDC346... RLMH_SALSV - Ribosomal RNA large subunit methyltransferase H OS=Salmonella schwarzengrund (strain CVM19633) GN=rl... lcl\|NC_016856.1_... - [gene=ybeA] [protein=SPOUT methyltransferase superfamily protein] [protein_id=YP_005236357.1] [locat... RLMH_SALPA - Ribosomal RNA large subunit methyltransferase H OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42... gi\|194459261, gi... - gi\|194472897\|ref\|ZP_03078881.1\| conserved hypothetical protein [Salmonella enterica subsp. enterica ... RLMH_SALHS - Ribosomal RNA large subunit methyltransferase H OS=Salmonella heidelberg (strain SL476) GN=rlmH PE=3... RLMH_SALNS - Ribosomal RNA large subunit methyltransferase H OS=Salmonella newport (strain SL254) GN=rlmH PE=3 SV... RLMH_SALDC - Ribosomal RNA large subunit methyltransferase H OS=Salmonella dublin (strain CT_02021853) GN=rlmH PE... RLMH_SALPK - Ribosomal RNA large subunit methyltransferase H OS=Salmonella paratyphi A (strain AKU_12601) GN=rlmH... gi\|197263988, gi... - gi\|197263988\|ref\|ZP_03164062.1\| conserved hypothetical protein [Salmonella enterica subsp. enterica ... RLMH_SALA4 - Ribosomal RNA large subunit methyltransferase H OS=Salmonella agona (strain SL483) GN=rlmH PE=3 SV=1 gi\|168236633, gi... - gi\|197290429\|gb\|EDY29785.1\| conserved hypothetical protein [Salmonella enterica subsp. enterica sero... gi\|168231654, gi... - gi\|205334109\|gb\|EDZ20873.1\| conserved hypothetical protein [Salmonella enterica subsp. enterica sero... gi\|205330952, gi... - gi\|205330952\|gb\|EDZ17716.1\| conserved hypothetical protein [Salmonella enterica subsp. enterica sero... gi\|167550823, gi... - gi\|205324218\|gb\|EDZ12057.1\| conserved hypothetical protein [Salmonella enterica subsp. enterica sero... gi\|168823256, gi... - gi\|205340471\|gb\|EDZ27235.1\| conserved hypothetical protein [Salmonella enterica subsp. enterica sero... gi\|168465816, gi... - gi\|195631962\|gb\|EDX50482.1\| conserved hypothetical protein [Salmonella enterica subsp. enterica sero... gi\|168264428, gi... - gi\|205347111\|gb\|EDZ33742.1\| conserved hypothetical protein [Salmonella enterica subsp. enterica sero... gi\|205340105, gi... - gi\|205340105\|gb\|EDZ26869.1\| conserved hypothetical protein [Salmonella enterica subsp. enterica sero...	241.0	[0..1]	[155..1]
gi\|30040420, gi\|... - gi\|30062175\|ref\|NP_836346.1\| SPOUT methyltransferase superfamily protein [Shigella flexneri 2a str. ...	240.0	[0..1]	[155..1]
gi\|192930926, gi... - gi\|75258628\|ref\|ZP_00730035.1\| COG1576: Uncharacterized conserved protein [Escherichia coli E22], gi... gi\|75236617, gi\|... - gi\|75236617\|ref\|ZP_00720705.1\| COG1576: Uncharacterized conserved protein [Escherichia coli E110019]... gi\|75226740, gi\|... - gi\|75226740\|ref\|ZP_00713693.1\| COG1576: Uncharacterized conserved protein [Escherichia coli B7A], gi... gi\|194411269, gi... - gi\|75207925\|ref\|ZP_00708371.1\| COG1576: Uncharacterized conserved protein [Escherichia coli B171], g...	239.0	[0..1]	[155..1]
RLMH_ACTP2 - Ribosomal RNA large subunit methyltransferase H OS=Actinobacillus pleuropneumoniae serotype 5b (stra... RLMH_ACTP7 - Ribosomal RNA large subunit methyltransferase H OS=Actinobacillus pleuropneumoniae serotype 7 (strai... gi\|53729247 - gi\|53729247\|ref\|ZP_00133777.2\| COG1576: Uncharacterized conserved protein [Actinobacillus pleuropneu...	239.0	[0..1]	[155..1]
RLMH_MANSM - Ribosomal RNA large subunit methyltransferase H OS=Mannheimia succiniciproducens (strain MBEL55E) GN...	239.0	[0..1]	[155..1]
RLMH_ACTSZ - Ribosomal RNA large subunit methyltransferase H OS=Actinobacillus succinogenes (strain ATCC 55618 / ...	238.0	[0..1]	[155..1]
RLMH_SALCH - Ribosomal RNA large subunit methyltransferase H OS=Salmonella choleraesuis GN=rlmH PE=3 SV=1 RLMH_SALCH - Ribosomal RNA large subunit methyltransferase H OS=Salmonella choleraesuis (strain SC-B67) GN=rlmH P... YBEA_SALCH - UPF0247 protein ybeA OS=Salmonella choleraesuis GN=ybeA PE=3 SV=1	238.0	[0..1]	[155..1]
RLMH_SHELP - Ribosomal RNA large subunit methyltransferase H OS=Shewanella loihica (strain ATCC BAA-1088 / PV-4) ...	235.0	[0..1]	[155..1]

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Predicted Domain #1

Region A:
Residues: [1-155]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLQLVAVGT KMPDWVQTGF TEYLRRFPKD MPFELIEIPA GKRGKNADIK RILDKEGEQM  60
   61 LAAAGKNRIV TLDIPGKPWD TPQLAAELER WKLDGRDVSL LIGGPEGLSP ACKAAAEQSW 120
  121 SLSALTLPHP LVRVLVAESL YRAWSITTNH PYHRE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	64.0
Match:	1ns5A
Description:	Hypothetical protein YbeA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
RNA methyltransferase activity	4.23455016472464	bayes_pls_golite062009
methyltransferase activity	3.59960278169345	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	3.51722801996622	bayes_pls_golite062009
rRNA methyltransferase activity	3.14976989427746	bayes_pls_golite062009
tRNA methyltransferase activity	2.33123191403389	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	2.23755555119187	bayes_pls_golite062009
tRNA (guanine) methyltransferase activity	2.14623472760939	bayes_pls_golite062009
tRNA (guanine-N1-)-methyltransferase activity	2.0947794364355	bayes_pls_golite062009
transferase activity	1.63934797352054	bayes_pls_golite062009
catalytic activity	0.797300463760338	bayes_pls_golite062009
rRNA (guanine) methyltransferase activity	0.319046095835882	bayes_pls_golite062009
binding	0.178115162253014	bayes_pls_golite062009
N-methyltransferase activity	0.118357993944566	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: