YRC Public Data Repository - Protein Structure Prediction

Protein:	YADE_ECOLI
Organism:	Escherichia coli
Length:	409 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YADE_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|74310748, gi\|... - gi\|74310748\|ref\|YP_309167.1\| hypothetical protein SSON_0138 [Shigella sonnei Ss046], gi\|73854225\|gb\|...	494.0	[0..1]	[409..1]
gi\|110804190, gi... - gi\|110804190\|ref\|YP_687710.1\| hypothetical protein SFV_0120 [Shigella flexneri 5 str. 8401], gi\|1106...	492.0	[0..1]	[409..1]
gi\|75258877, gi\|... - gi\|75258877\|ref\|ZP_00730267.1\| COG0726: Predicted xylanase/chitin deacetylase [Escherichia coli E22]... gi\|192958992, gi... - gi\|75238837\|ref\|ZP_00722819.1\| COG0726: Predicted xylanase/chitin deacetylase [Escherichia coli E110... gi\|75230505, gi\|... - gi\|75230505\|ref\|ZP_00716986.1\| COG0726: Predicted xylanase/chitin deacetylase [Escherichia coli B7A]... gi\|75210457, gi\|... - gi\|75210457\|ref\|ZP_00710608.1\| COG0726: Predicted xylanase/chitin deacetylase [Escherichia coli B171... gi\|209910580, gi... - gi\|209917321\|ref\|YP_002291405.1\| hypothetical protein ECSE_0130 [Escherichia coli SE11], gi\|20991058... gi\|218350328, gi... - gi\|218693596\|ref\|YP_002401263.1\| putative exported polysaccharide deacetylase [Escherichia coli 5598...	492.0	[0..1]	[409..1]
gi\|110640349, gi... - gi\|110640349\|ref\|YP_668077.1\| YadE protein, polysaccharide deacetylase [Escherichia coli 536], gi\|11... gi\|26106467, gi\|... - gi\|26246070\|ref\|NP_752109.1\| hypothetical protein c0159 [Escherichia coli CFT073], gi\|26106467\|gb\|AA... gi\|75240278 - gi\|75240278\|ref\|ZP_00724225.1\| COG0726: Predicted xylanase/chitin deacetylase [Escherichia coli F11] gi\|218688008, gi... - gi\|218688008\|ref\|YP_002396220.1\| putative exported polysaccharide deacetylase [Escherichia coli ED1a...	492.0	[0..1]	[409..1]
gi\|157156843, gi... - gi\|75189229\|ref\|ZP_00702496.1\| COG0726: Predicted xylanase/chitin deacetylase [Escherichia coli E243...	490.0	[0..1]	[409..1]
gi\|237704286, gi... - gi\|237704286\|ref\|ZP_04534767.1\| YadE protein [Escherichia sp. 3_2_53FAA], gi\|226902198\|gb\|EEH88457.1... gi\|218363842, gi... - gi\|218557073\|ref\|YP_002389986.1\| putative exported polysaccharide deacetylase [Escherichia coli S88]... gi\|91070772, gi\|... - gi\|91209198\|ref\|YP_539184.1\| hypothetical protein UTI89_C0143 [Escherichia coli UTI89], gi\|91070772\|... gi\|117622417, gi... - gi\|117622417\|ref\|YP_851330.1\| hypothetical protein APECO1_1855 [Escherichia coli APEC O1], gi\|115511...	490.0	[0..1]	[409..1]
gi\|30061695, gi\|... - gi\|30061695\|ref\|NP_835866.1\| hypothetical protein S0129 [Shigella flexneri 2a str. 2457T], gi\|300399... gi\|56479609, gi\|... - gi\|56479609\|ref\|NP_706083.2\| hypothetical protein SF0127 [Shigella flexneri 2a str. 301], gi\|5638316...	490.0	[0..1]	[409..1]
gi\|15829388, gi\|... - gi\|15829388\|ref\|NP_308161.1\| hypothetical protein ECs0134 [Escherichia coli O157:H7 str. Sakai], gi\|... gi\|189360680, gi... - gi\|189360680\|gb\|EDU79099.1\| polysaccharide deacetylase domain protein [Escherichia coli O157:H7 str.... gi\|168764727, gi... - gi\|189365328\|gb\|EDU83744.1\| polysaccharide deacetylase domain protein [Escherichia coli O157:H7 str.... gi\|189357037, gi... - gi\|189357037\|gb\|EDU75456.1\| polysaccharide deacetylase domain protein [Escherichia coli O157:H7 str.... gi\|168752448, gi... - gi\|188013710\|gb\|EDU51832.1\| polysaccharide deacetylase domain protein [Escherichia coli O157:H7 str.... gi\|189376415, gi... - gi\|189376415\|gb\|EDU94831.1\| polysaccharide deacetylase domain protein [Escherichia coli O157:H7 str.... gi\|168789237, gi... - gi\|189371139\|gb\|EDU89555.1\| polysaccharide deacetylase domain protein [Escherichia coli O157:H7 str.... gi\|168782020, gi... - gi\|189000496\|gb\|EDU69482.1\| polysaccharide deacetylase domain protein [Escherichia coli O157:H7 str.... gi\|187767821, gi... - gi\|187767821\|gb\|EDU31665.1\| polysaccharide deacetylase domain protein [Escherichia coli O157:H7 str.... gi\|254590665, gi... - gi\|254791265\|ref\|YP_003076102.1\| predicted polysaccharide deacetylase lipoprotein [Escherichia coli ... gi\|209746162, gi... - pir\|\|F85496 hypothetical protein yadE [imported] - Escherichia coli (strain O157:H7, substrain EDL9... gi\|208741854, gi... - gi\|208821731\|ref\|ZP_03262051.1\| polysaccharide deacetylase domain protein [Escherichia coli O157:H7 ... gi\|208814363, gi... - gi\|208814363\|ref\|ZP_03255692.1\| polysaccharide deacetylase domain protein [Escherichia coli O157:H7 ... gi\|15799814, gi\|... - gi\|15799814\|ref\|NP_285826.1\| hypothetical protein Z0141 [Escherichia coli O157:H7 EDL933], gi\|125128... gi\|208809292, gi... - gi\|208809292\|ref\|ZP_03251629.1\| polysaccharide deacetylase domain protein [Escherichia coli O157:H7 ... gi\|15829388, gi\|... - gi\|15829388\|ref\|NP_308161.1\| hypothetical protein ECs0134 [Escherichia coli O157:H7], gi\|13359590\|db... gi\|195938188 - gi\|195938188\|ref\|ZP_03083570.1\| hypothetical protein EscherichcoliO157_17436 [Escherichia coli O157:... gi\|217326386, gi... - gi\|217326386\|ref\|ZP_03442470.1\| polysaccharide deacetylase domain protein [Escherichia coli O157:H7 ... gi\|209396198, gi... - gi\|209396198\|ref\|YP_002268738.1\| polysaccharide deacetylase domain protein [Escherichia coli O157:H7...	489.0	[0..1]	[409..1]
gi\|157159598, gi... - gi\|75194345\|ref\|ZP_00704415.1\| COG0726: Predicted xylanase/chitin deacetylase [Escherichia coli HS],...	489.0	[0..1]	[409..1]
gi\|194418319, gi... - gi\|83569711\|ref\|ZP_00921161.1\| COG0726: Predicted xylanase/chitin deacetylase [Shigella dysenteriae ...	488.0	[0..1]	[409..1]

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Predicted Domain #1

Region A:
Residues: [1-143]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYKQAVILLL MLFTASVSAA LPARYMQTIE NAAVWAQIGD KMVTVGNIRA GQIIAVEPTA  60
   61 ASYYAFNFGF GKGFIDKGHL EPVQGRQKVE DGLGDLNKPL SNQNLVTWKD TPVYNAPSAG 120
  121 SAPFGVLADN LRYPILHKLK DRL

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [144-227]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NQTWYQIRIG DRLAYISALD AQPDNGLSVL TYHHILRDEE NTRFRHTSTT TSVRAFNNQM  60
   61 AWLRDRGYAT LSMVQLEGYV KNKI

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [228-409]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLPARAVVIT FDDGLKSVSR YAYPVLKQYG MKATAFIVTS RIKRHPQKWN PKSLQFMSVS  60
   61 ELNEIRDVFD FQSHTHFLHR VDGYRRPILL SRSEHNILFD FARSRRALAQ FNPHVWYLSY 120
  121 PFGGFNDNAV KAANDAGFHL AVTTMKGKVK PGDNPLLLKR LYILRTDSLE TMSRLVSNQP 180
  181 QG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	31.045757
Match:	1w17A
Description:	Structure of Bacillus subtilis PdaA, a family 4 Carbohydrate esterase.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.782831911848012	bayes_pls_golite062009
hydrolase activity	0.396958708976783	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: