YRC Public Data Repository - Protein Structure Prediction

Protein:	YADE_ECOLI
Organism:	Escherichia coli
Length:	409 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YADE_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|74310748, gi\|... - gi\|74310748\|ref\|YP_309167.1\| hypothetical protein SSON_0138 [Shigella sonnei Ss046], gi\|73854225\|gb\|...	494.0	[0..1]	[409..1]
gi\|110804190, gi... - gi\|110804190\|ref\|YP_687710.1\| hypothetical protein SFV_0120 [Shigella flexneri 5 str. 8401], gi\|1106...	492.0	[0..1]	[409..1]
gi\|75258877, gi\|... - gi\|75258877\|ref\|ZP_00730267.1\| COG0726: Predicted xylanase/chitin deacetylase [Escherichia coli E22]... gi\|192958992, gi... - gi\|75238837\|ref\|ZP_00722819.1\| COG0726: Predicted xylanase/chitin deacetylase [Escherichia coli E110... gi\|75230505, gi\|... - gi\|75230505\|ref\|ZP_00716986.1\| COG0726: Predicted xylanase/chitin deacetylase [Escherichia coli B7A]... gi\|75210457, gi\|... - gi\|75210457\|ref\|ZP_00710608.1\| COG0726: Predicted xylanase/chitin deacetylase [Escherichia coli B171... gi\|209910580, gi... - gi\|209917321\|ref\|YP_002291405.1\| hypothetical protein ECSE_0130 [Escherichia coli SE11], gi\|20991058... gi\|218350328, gi... - gi\|218693596\|ref\|YP_002401263.1\| putative exported polysaccharide deacetylase [Escherichia coli 5598...	492.0	[0..1]	[409..1]
gi\|110640349, gi... - gi\|110640349\|ref\|YP_668077.1\| YadE protein, polysaccharide deacetylase [Escherichia coli 536], gi\|11... gi\|26106467, gi\|... - gi\|26246070\|ref\|NP_752109.1\| hypothetical protein c0159 [Escherichia coli CFT073], gi\|26106467\|gb\|AA... gi\|75240278 - gi\|75240278\|ref\|ZP_00724225.1\| COG0726: Predicted xylanase/chitin deacetylase [Escherichia coli F11] gi\|218688008, gi... - gi\|218688008\|ref\|YP_002396220.1\| putative exported polysaccharide deacetylase [Escherichia coli ED1a...	492.0	[0..1]	[409..1]
gi\|157156843, gi... - gi\|75189229\|ref\|ZP_00702496.1\| COG0726: Predicted xylanase/chitin deacetylase [Escherichia coli E243...	490.0	[0..1]	[409..1]
gi\|237704286, gi... - gi\|237704286\|ref\|ZP_04534767.1\| YadE protein [Escherichia sp. 3_2_53FAA], gi\|226902198\|gb\|EEH88457.1... gi\|218363842, gi... - gi\|218557073\|ref\|YP_002389986.1\| putative exported polysaccharide deacetylase [Escherichia coli S88]... gi\|91070772, gi\|... - gi\|91209198\|ref\|YP_539184.1\| hypothetical protein UTI89_C0143 [Escherichia coli UTI89], gi\|91070772\|... gi\|117622417, gi... - gi\|117622417\|ref\|YP_851330.1\| hypothetical protein APECO1_1855 [Escherichia coli APEC O1], gi\|115511...	490.0	[0..1]	[409..1]
gi\|30061695, gi\|... - gi\|30061695\|ref\|NP_835866.1\| hypothetical protein S0129 [Shigella flexneri 2a str. 2457T], gi\|300399... gi\|56479609, gi\|... - gi\|56479609\|ref\|NP_706083.2\| hypothetical protein SF0127 [Shigella flexneri 2a str. 301], gi\|5638316...	490.0	[0..1]	[409..1]
gi\|15829388, gi\|... - gi\|15829388\|ref\|NP_308161.1\| hypothetical protein ECs0134 [Escherichia coli O157:H7 str. Sakai], gi\|... gi\|189360680, gi... - gi\|189360680\|gb\|EDU79099.1\| polysaccharide deacetylase domain protein [Escherichia coli O157:H7 str.... gi\|168764727, gi... - gi\|189365328\|gb\|EDU83744.1\| polysaccharide deacetylase domain protein [Escherichia coli O157:H7 str.... gi\|189357037, gi... - gi\|189357037\|gb\|EDU75456.1\| polysaccharide deacetylase domain protein [Escherichia coli O157:H7 str.... gi\|168752448, gi... - gi\|188013710\|gb\|EDU51832.1\| polysaccharide deacetylase domain protein [Escherichia coli O157:H7 str.... gi\|189376415, gi... - gi\|189376415\|gb\|EDU94831.1\| polysaccharide deacetylase domain protein [Escherichia coli O157:H7 str.... gi\|168789237, gi... - gi\|189371139\|gb\|EDU89555.1\| polysaccharide deacetylase domain protein [Escherichia coli O157:H7 str.... gi\|168782020, gi... - gi\|189000496\|gb\|EDU69482.1\| polysaccharide deacetylase domain protein [Escherichia coli O157:H7 str.... gi\|187767821, gi... - gi\|187767821\|gb\|EDU31665.1\| polysaccharide deacetylase domain protein [Escherichia coli O157:H7 str.... gi\|254590665, gi... - gi\|254791265\|ref\|YP_003076102.1\| predicted polysaccharide deacetylase lipoprotein [Escherichia coli ... gi\|209746162, gi... - pir\|\|F85496 hypothetical protein yadE [imported] - Escherichia coli (strain O157:H7, substrain EDL9... gi\|208741854, gi... - gi\|208821731\|ref\|ZP_03262051.1\| polysaccharide deacetylase domain protein [Escherichia coli O157:H7 ... gi\|208814363, gi... - gi\|208814363\|ref\|ZP_03255692.1\| polysaccharide deacetylase domain protein [Escherichia coli O157:H7 ... gi\|15799814, gi\|... - gi\|15799814\|ref\|NP_285826.1\| hypothetical protein Z0141 [Escherichia coli O157:H7 EDL933], gi\|125128... gi\|208809292, gi... - gi\|208809292\|ref\|ZP_03251629.1\| polysaccharide deacetylase domain protein [Escherichia coli O157:H7 ... gi\|15829388, gi\|... - gi\|15829388\|ref\|NP_308161.1\| hypothetical protein ECs0134 [Escherichia coli O157:H7], gi\|13359590\|db... gi\|195938188 - gi\|195938188\|ref\|ZP_03083570.1\| hypothetical protein EscherichcoliO157_17436 [Escherichia coli O157:... gi\|217326386, gi... - gi\|217326386\|ref\|ZP_03442470.1\| polysaccharide deacetylase domain protein [Escherichia coli O157:H7 ... gi\|209396198, gi... - gi\|209396198\|ref\|YP_002268738.1\| polysaccharide deacetylase domain protein [Escherichia coli O157:H7...	489.0	[0..1]	[409..1]
gi\|157159598, gi... - gi\|75194345\|ref\|ZP_00704415.1\| COG0726: Predicted xylanase/chitin deacetylase [Escherichia coli HS],...	489.0	[0..1]	[409..1]
gi\|194418319, gi... - gi\|83569711\|ref\|ZP_00921161.1\| COG0726: Predicted xylanase/chitin deacetylase [Shigella dysenteriae ...	488.0	[0..1]	[409..1]

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Predicted Domain #1

Region A:
Residues: [1-143]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYKQAVILLL MLFTASVSAA LPARYMQTIE NAAVWAQIGD KMVTVGNIRA GQIIAVEPTA  60
   61 ASYYAFNFGF GKGFIDKGHL EPVQGRQKVE DGLGDLNKPL SNQNLVTWKD TPVYNAPSAG 120
  121 SAPFGVLADN LRYPILHKLK DRL

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.538	N/A	N/A	c.58.1	Aminoacid dehydrogenase-like, N-terminal domain
View	Download	0.447	N/A	N/A	a.1.1	Globin-like
View	Download	0.405	N/A	N/A	a.1.1	Globin-like
View	Download	0.397	N/A	N/A	a.24.14	FAT domain of focal adhesion kinase
View	Download	0.395	N/A	N/A	c.58.1	Aminoacid dehydrogenase-like, N-terminal domain

Predicted Domain #2

Region A:
Residues: [144-227]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NQTWYQIRIG DRLAYISALD AQPDNGLSVL TYHHILRDEE NTRFRHTSTT TSVRAFNNQM  60
   61 AWLRDRGYAT LSMVQLEGYV KNKI

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [228-409]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLPARAVVIT FDDGLKSVSR YAYPVLKQYG MKATAFIVTS RIKRHPQKWN PKSLQFMSVS  60
   61 ELNEIRDVFD FQSHTHFLHR VDGYRRPILL SRSEHNILFD FARSRRALAQ FNPHVWYLSY 120
  121 PFGGFNDNAV KAANDAGFHL AVTTMKGKVK PGDNPLLLKR LYILRTDSLE TMSRLVSNQP 180
  181 QG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	31.045757
Match:	1w17A
Description:	Structure of Bacillus subtilis PdaA, a family 4 Carbohydrate esterase.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.782831911848012	bayes_pls_golite062009
hydrolase activity	0.396958708976783	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: