YRC Public Data Repository - Protein Structure Prediction

Protein:	TRPA_ECOLI
Organism:	Escherichia coli
Length:	268 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TRPA_ECOLI.

Description	E-value	Query Range	Subject Range
TRPA_NITEU - Tryptophan synthase alpha chain OS=Nitrosomonas europaea GN=trpA PE=3 SV=1 TRPA_NITEU - Tryptophan synthase alpha chain OS=Nitrosomonas europaea (strain ATCC 19718 / NBRC 14298) GN=trpA PE...	284.0	[0..1]	[268..1]
gi\|94498942, gi\|... - gi\|94498942\|ref\|ZP_01305480.1\| tryptophan synthase, alpha subunit [Oceanobacter sp. RED65], gi\|94428...	284.0	[0..1]	[267..1]
gi\|71549023, gi\|... - gi\|71549023\|ref\|ZP_00669247.1\| Tryptophan synthase, alpha chain [Nitrosomonas eutropha C71], gi\|7148...	281.0	[0..1]	[268..1]
gi\|67925738, gi\|... - gi\|67925738\|ref\|ZP_00519045.1\| Tryptophan synthase, alpha chain [Crocosphaera watsonii WH 8501], gi\|...	280.0	[0..1]	[266..1]
TRPA_SYNP2 - Tryptophan synthase alpha chain OS=Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) GN=trpA P...	279.0	[0..1]	[266..1]
gi\|86605970, gi\|... - gi\|86605970\|ref\|YP_474733.1\| tryptophan synthase subunit alpha [Synechococcus sp. JA-3-3Ab], gi\|8655... gi\|86605970 - gi\|86605970\|ref\|YP_474733.1\| tryptophan synthase, alpha subunit [Cyanobacteria bacterium Yellowstone...	279.0	[0..2]	[266..3]
TRPA_SYNAS - Tryptophan synthase alpha chain OS=Syntrophus aciditrophicus (strain SB) GN=trpA PE=3 SV=1	278.0	[0..1]	[266..1]
TRPA_PSEPF - Tryptophan synthase alpha chain OS=Pseudomonas fluorescens (strain Pf0-1) GN=trpA PE=3 SV=1	278.0	[0..1]	[267..1]
TRPA1_ARATH - Tryptophan synthase alpha chain OS=Arabidopsis thaliana GN=TRPA1 PE=1 SV=2	277.0	[0..4]	[266..13]
gi\|83633277, gi\|... - gi\|83645234\|ref\|YP_433669.1\| tryptophan synthase subunit alpha [Hahella chejuensis KCTC 2396], gi\|83...	277.0	[0..1]	[267..1]

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Predicted Domain #1

Region A:
Residues: [1-268]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MERYESLFAQ LKERKEGAFV PFVTLGDPGI EQSLKIIDTL IEAGADALEL GIPFSDPLAD  60
   61 GPTIQNATLR AFAAGVTPAQ CFEMLALIRQ KHPTIPIGLL MYANLVFNKG IDEFYAQCEK 120
  121 VGVDSVLVAD VPVEESAPFR QAALRHNVAP IFICPPNADD DLLRQIASYG RGYTYLLSRA 180
  181 GVTGAENRAA LPLNHLVAKL KEYNAAPPLQ GFGISAPDQV KAAIDAGAAG AISGSAIVKI 240
  241 IEQHINEPEK MLAALKVFVQ PMKAATRS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	70.0
Match:	1v7yA
Description:	Crystal structure of tryptophan synthase alpha-subunit from Escherichia coli at room temperature
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.91225195041472	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: