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View Structure Prediction Details

Protein: TPIS_PLAFA
Organism: Plasmodium falciparum
Length: 248 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TPIS_PLAFA.

Description E-value Query
Range
Subject
Range
gi|109505678 - gi|109505678|ref|XP_001064421.1| PREDICTED: similar to triosephosphate isomerase [Rattus norvegicus]
367.0 [0..2] [246..4]
gi|66360365, gi|... - gi|66360366|pdb|1WYI|B Chain B, Human Triosephosphate Isomerase Of New Crystal Form, gi|66360365|pdb...
366.0 [0..2] [246..5]
gi|223374 - gi|223374|prf||0801190A isomerase,triosephosphate
TPIS_RABIT - Triosephosphate isomerase OS=Oryctolagus cuniculus GN=TPI1 PE=1 SV=1
365.0 [0..2] [246..3]
gi|55730014 - gi|55730014|emb|CAH91732.1| hypothetical protein [Pongo abelii]
TPIS_PONAB - Triosephosphate isomerase OS=Pongo abelii GN=TPI1 PE=2 SV=1
365.0 [0..2] [246..4]

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Predicted Domain #1
Region A:
Residues: [1-248]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MARKYFVAAN WKCNGTLESI KSLTNSFNNL DFDPSKLDVV VFPVSVHYDH TRKLLQSKFS  60
   61 TGIQNVSKFG NGSYTGEVSA EIAKDLNIEY VIIGHFERRK YFHETDEDVR EKLQASLKNN 120
  121 LKAVVCFGES LEQREQNKTI EVITKQVKAF VDLIDNFDNV ILAYEPLWAI GTGKTATPEQ 180
  181 AQLVHKEIRK IVKDTCGEKQ ANQIRILYGG SVNTENCSSL IQQEDIDGFL VGNASLKESF 240
  241 VDIIKSAM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 89.0
Match: 1lyxA
Description: Triosephosphate isomerase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
triose-phosphate isomerase activity 5.94525596131351 bayes_pls_golite062009
intramolecular oxidoreductase activity 4.11751506069887 bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting aldoses and ketoses 3.62219160185043 bayes_pls_golite062009
isomerase activity 2.06271139232842 bayes_pls_golite062009
binding 1.80264931081179 bayes_pls_golite062009
catalytic activity 1.7524198174984 bayes_pls_golite062009
protein binding 0.33788557654084 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle