YRC Public Data Repository - Protein Structure Prediction

Protein:	TGT_ECOLI
Organism:	Escherichia coli
Length:	375 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TGT_ECOLI.

Description	E-value	Query Range	Subject Range
TGT_SALPA - Queuine tRNA-ribosyltransferase OS=Salmonella paratyphi A GN=tgt PE=3 SV=1 TGT_SALPA - Queuine tRNA-ribosyltransferase OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=tgt PE=3 SV... TGT_SALPK - Queuine tRNA-ribosyltransferase OS=Salmonella paratyphi A (strain AKU_12601) GN=tgt PE=3 SV=1	587.0	[0..1]	[375..1]
TGT_SHIFL - Queuine tRNA-ribosyltransferase OS=Shigella flexneri GN=tgt PE=3 SV=1 gi\|24111784, gi\|... - gi\|24111784\|ref\|NP_706294.1\| queuine tRNA-ribosyltransferase [Shigella flexneri 2a str. 301], gi\|240... gi\|30040145, gi\|... - gi\|30061901\|ref\|NP_836072.1\| queuine tRNA-ribosyltransferase [Shigella flexneri 2a str. 2457T], gi\|3... TGT_SHIF8 - Queuine tRNA-ribosyltransferase OS=Shigella flexneri serotype 5b (strain 8401) GN=tgt PE=3 SV=1	586.0	[0..1]	[375..1]
gi\|205329470, gi... - gi\|205329470\|gb\|EDZ16234.1\| queuine tRNA-ribosyltransferase [Salmonella enterica subsp. enterica ser... TGT_SALTY - Queuine tRNA-ribosyltransferase OS=Salmonella typhimurium GN=tgt PE=3 SV=1 gi\|205333452, gi... - gi\|205333452\|gb\|EDZ20216.1\| queuine tRNA-ribosyltransferase [Salmonella enterica subsp. enterica ser... TGT_SALPB - Queuine tRNA-ribosyltransferase OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=tgt PE=3 ... gi\|197289492, gi... - gi\|197289492\|gb\|EDY28855.1\| queuine tRNA-ribosyltransferase [Salmonella enterica subsp. enterica ser... TGT_SALTY - Queuine tRNA-ribosyltransferase OS=Salmonella typhimurium GN=tgt PE=3 SV=1 lcl\|NC_016856.1_... - [gene=tgt] [protein=queuine tRNA-ribosyltransferase] [protein_id=YP_005236096.1] [location=461514..4... TGT_SALTY - Queuine tRNA-ribosyltransferase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=t... gi\|238911461 - gi\|238911461\|ref\|ZP_04655298.1\| queuine tRNA-ribosyltransferase [Salmonella enterica subsp. enterica... TGT_SALA4 - Queuine tRNA-ribosyltransferase OS=Salmonella agona (strain SL483) GN=tgt PE=3 SV=1 gi\|197242718, gi... - gi\|197264463\|ref\|ZP_03164537.1\| queuine tRNA-ribosyltransferase [Salmonella enterica subsp. enterica... gi\|200390123, gi... - gi\|200390123\|ref\|ZP_03216734.1\| queuine tRNA-ribosyltransferase [Salmonella enterica subsp. enterica... gi\|204926711, gi... - gi\|204926711\|ref\|ZP_03217913.1\| queuine tRNA-ribosyltransferase [Salmonella enterica subsp. enterica... TGT_SALNS - Queuine tRNA-ribosyltransferase OS=Salmonella newport (strain SL254) GN=tgt PE=3 SV=1 TGT_SALHS - Queuine tRNA-ribosyltransferase OS=Salmonella heidelberg (strain SL476) GN=tgt PE=3 SV=1 gi\|194457563, gi... - gi\|194471199\|ref\|ZP_03077183.1\| queuine tRNA-ribosyltransferase [Salmonella enterica subsp. enterica... TGT_SALSV - Queuine tRNA-ribosyltransferase OS=Salmonella schwarzengrund (strain CVM19633) GN=tgt PE=3 SV=1 gi\|168240225, gi... - gi\|205340287\|gb\|EDZ27051.1\| queuine tRNA-ribosyltransferase [Salmonella enterica subsp. enterica ser... TGT_SALPB - Queuine tRNA-ribosyltransferase OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=tgt PE=3 ... gi\|168261165, gi... - gi\|205349783\|gb\|EDZ36414.1\| queuine tRNA-ribosyltransferase [Salmonella enterica subsp. enterica ser... gi\|195631915, gi... - gi\|195631915\|gb\|EDX50435.1\| queuine tRNA-ribosyltransferase [Salmonella enterica subsp. enterica ser... gi\|205344228, gi... - gi\|205344228\|gb\|EDZ30992.1\| queuine tRNA-ribosyltransferase [Salmonella enterica subsp. enterica ser...	586.0	[0..1]	[375..1]
TGT_SALCH - Queuine tRNA-ribosyltransferase OS=Salmonella choleraesuis (strain SC-B67) GN=tgt PE=3 SV=1 TGT_SALPC - Queuine tRNA-ribosyltransferase OS=Salmonella paratyphi C (strain RKS4594) GN=tgt PE=3 SV=1 TGT_SALCH - Queuine tRNA-ribosyltransferase OS=Salmonella choleraesuis GN=tgt PE=3 SV=1 TGT_SALCH - Queuine tRNA-ribosyltransferase OS=Salmonella choleraesuis GN=tgt PE=3 SV=1	585.0	[0..1]	[375..1]
gi\|213580921 - gi\|213580921\|ref\|ZP_03362747.1\| queuine tRNA-ribosyltransferase [Salmonella enterica subsp. enterica... TGT_SALTI - Queuine tRNA-ribosyltransferase OS=Salmonella typhi GN=tgt PE=3 SV=1 gi\|213609614 - gi\|213609614\|ref\|ZP_03369440.1\| queuine tRNA-ribosyltransferase [Salmonella enterica subsp. enterica... gi\|213650158 - gi\|213650158\|ref\|ZP_03380211.1\| queuine tRNA-ribosyltransferase [Salmonella enterica subsp. enterica... gi\|214000362 - gi\|214000362\|ref\|ZP_03411097.1\| queuine tRNA-ribosyltransferase [Salmonella enterica subsp. enterica... gi\|29142846, gi\|... - gi\|29142846\|ref\|NP_806188.1\| queuine tRNA-ribosyltransferase [Salmonella enterica subsp. enterica se... gi\|213163213 - gi\|213163213\|ref\|ZP_03348923.1\| queuine tRNA-ribosyltransferase [Salmonella enterica subsp. enterica... gi\|16759383 - gi\|16759383\|ref\|NP_455000.1\| queuine tRNA-ribosyltransferase [Salmonella enterica subsp. enterica se... gi\|213427839 - gi\|213427839\|ref\|ZP_03360589.1\| queuine tRNA-ribosyltransferase [Salmonella enterica subsp. enterica... TGT_SALTI - Queuine tRNA-ribosyltransferase OS=Salmonella typhi GN=tgt PE=3 SV=1	585.0	[0..1]	[375..1]
gi\|147966 - gi\|147966\|gb\|AAA24667.1\| transfer RNA-guanine transglycosylase	585.0	[0..1]	[375..1]
TGT_PHOLL - Queuine tRNA-ribosyltransferase OS=Photorhabdus luminescens subsp. laumondii GN=tgt PE=3 SV=1 TGT_PHOLL - Queuine tRNA-ribosyltransferase OS=Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP...	583.0	[0..1]	[372..1]
gi\|89072680, gi\|... - gi\|89072680\|ref\|ZP_01159245.1\| queuine tRNA-ribosyltransferase [Photobacterium sp. SKA34], gi\|890515...	583.0	[0..1]	[372..1]
gi\|90579386, gi\|... - gi\|90579386\|ref\|ZP_01235196.1\| queuine tRNA-ribosyltransferase [Vibrio angustum S14], gi\|90440219\|gb...	583.0	[0..1]	[372..1]
gi\|238720690, gi... - gi\|77962938\|ref\|ZP_00826753.1\| COG0343: Queuine/archaeosine tRNA-ribosyltransferase [Yersinia mollar...	583.0	[0..1]	[374..1]

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Predicted Domain #1

Region A:
Residues: [1-375]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKFELDTTDG RARRGRLVFD RGVVETPCFM PVGTYGTVKG MTPEEVEATG AQIILGNTFH  60
   61 LWLRPGQEIM KLHGDLHDFM QWKGPILTDS GGFQVFSLGD IRKITEQGVH FRNPINGDPI 120
  121 FLDPEKSMEI QYDLGSDIVM IFDECTPYPA DWDYAKRSME MSLRWAKRSR ERFDSLGNKN 180
  181 ALFGIIQGSV YEDLRDISVK GLVDIGFDGY AVGGLAVGEP KADMHRILEH VCPQIPADKP 240
  241 RYLMGVGKPE DLVEGVRRGI DMFDCVMPTR NARNGHLFVT DGVVKIRNAK YKSDTGPLDP 300
  301 ECDCYTCRNY SRAYLHHLDR CNEILGARLN TIHNLRYYQR LMAGLRKAIE EGKLESFVTD 360
  361 FYQRQGREVP PLNVD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	150.0
Match:	1ozmA
Description:	Y106F mutant of Z. mobilis TGT
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
queuine tRNA-ribosyltransferase activity	5.68673071384353	bayes_pls_golite062009
transferase activity	3.21194535271238	bayes_pls_golite062009
transferase activity, transferring pentosyl groups	2.84864811414771	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	2.53039738178366	bayes_pls_golite062009
catalytic activity	2.02168745464921	bayes_pls_golite062009
binding	1.29132603807317	bayes_pls_golite062009
protein binding	0.136438951368546	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: