YRC Public Data Repository - Protein Structure Prediction

Protein:	SURA_ECOLI
Organism:	Escherichia coli
Length:	428 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SURA_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|77976135, gi\|... - gi\|77976135\|ref\|ZP_00831668.1\| COG0760: Parvulin-like peptidyl-prolyl isomerase [Yersinia frederikse...	328.0	[0..1]	[427..1]
gi\|77959759, gi\|... - gi\|77959759\|ref\|ZP_00823776.1\| COG0760: Parvulin-like peptidyl-prolyl isomerase [Yersinia bercovieri...	325.0	[0..1]	[427..1]
SURA_SALCH - Chaperone SurA OS=Salmonella choleraesuis (strain SC-B67) GN=surA PE=3 SV=1 SURA_SALCH - Chaperone surA OS=Salmonella choleraesuis GN=surA PE=3 SV=1 SURA_SALCH - Chaperone surA OS=Salmonella choleraesuis GN=surA PE=3 SV=1	324.0	[0..1]	[425..1]
gi\|77961918, gi\|... - gi\|77961918\|ref\|ZP_00825746.1\| COG0760: Parvulin-like peptidyl-prolyl isomerase [Yersinia mollaretii...	322.0	[0..1]	[427..1]
gi\|77976651, gi\|... - gi\|77976651\|ref\|ZP_00832128.1\| COG0760: Parvulin-like peptidyl-prolyl isomerase [Yersinia intermedia...	322.0	[0..1]	[427..1]
gi\|167401555, gi... - gi\|167401555\|ref\|ZP_02307049.1\| chaperone SurA [Yersinia pestis biovar Antiqua str. UG05-0454], gi\|1... SURA_YERPA - Chaperone SurA OS=Yersinia pestis bv. Antiqua (strain Antiqua) GN=surA PE=3 SV=1	322.0	[0..1]	[427..1]
SURA_YERPS - Chaperone surA OS=Yersinia pseudotuberculosis GN=surA PE=3 SV=1 gi\|165919954, gi... - gi\|165928093\|ref\|ZP_02223925.1\| chaperone SurA [Yersinia pestis biovar Orientalis str. F1991016], gi... SURA_YERPE - Chaperone SurA OS=Yersinia pestis GN=surA PE=3 SV=1 gi\|152960604, gi... - gi\|77631618\|ref\|ZP_00794204.1\| COG0760: Parvulin-like peptidyl-prolyl isomerase [Yersinia pseudotube... gi\|45443417, gi\|... - gi\|45443417\|ref\|NP_994956.1\| peptidyl-prolyl cis-trans isomerase SurA [Yersinia pestis biovar Microt... gi\|21960659, gi\|... - gi\|22127555\|ref\|NP_670978.1\| peptidyl-prolyl cis-trans isomerase SurA [Yersinia pestis KIM], gi\|2196... gi\|15978588, gi\|... - gi\|218927692\|ref\|YP_002345567.1\| peptidyl-prolyl cis-trans isomerase SurA [Yersinia pestis CO92], gi... gi\|229836923, gi... - gi\|229836923\|ref\|ZP_04457088.1\| peptidyl-prolyl cis-trans isomerase (PPIase) [Yersinia pestis Pestoi... SURA_YERPS - Chaperone SurA OS=Yersinia pseudotuberculosis serotype I (strain IP32953) GN=surA PE=3 SV=1 gi\|229840382, gi... - gi\|229840382\|ref\|ZP_04460541.1\| peptidyl-prolyl cis-trans isomerase (PPIase) [Yersinia pestis biovar... gi\|229690772, gi... - gi\|229842462\|ref\|ZP_04462617.1\| peptidyl-prolyl cis-trans isomerase (PPIase) [Yersinia pestis biovar... gi\|150260469, gi... - gi\|150260469\|ref\|ZP_01917197.1\| survival protein SurA precursor (peptidyl-prolyl cis-trans isomerase... gi\|145600395, gi... - gi\|145600395\|ref\|YP_001164471.1\| peptidyl-prolyl cis-trans isomerase SurA [Yersinia pestis Pestoides... gi\|166206966, gi... - gi\|166212220\|ref\|ZP_02238255.1\| chaperone SurA [Yersinia pestis biovar Antiqua str. B42003004], gi\|1... gi\|166008803, gi... - gi\|166008803\|ref\|ZP_02229701.1\| chaperone SurA [Yersinia pestis biovar Antiqua str. E1979001], gi\|16... gi\|167426071, gi... - gi\|167426071\|ref\|ZP_02317824.1\| chaperone SurA [Yersinia pestis biovar Mediaevalis str. K1973002], g... gi\|167422012, gi... - gi\|167422012\|ref\|ZP_02313765.1\| chaperone SurA [Yersinia pestis biovar Orientalis str. MG05-1020], g... gi\|89102171, gi\|... - gi\|89102171\|ref\|ZP_01174826.1\| COG0760: Parvulin-like peptidyl-prolyl isomerase [Yersinia pestis bio... gi\|170025786, gi... - gi\|170025786\|ref\|YP_001722291.1\| peptidyl-prolyl cis-trans isomerase SurA [Yersinia pseudotuberculos... SURA_YERPN - Chaperone SurA OS=Yersinia pestis bv. Antiqua (strain Nepal516) GN=surA PE=3 SV=1 gi\|167470553 - gi\|167470553\|ref\|ZP_02335257.1\| chaperone SurA [Yersinia pestis FV-1] gi\|186893987, gi... - gi\|186893987\|ref\|YP_001871099.1\| peptidyl-prolyl cis-trans isomerase SurA [Yersinia pseudotuberculos...	321.0	[0..1]	[427..1]
gi\|162352906, gi... - gi\|77634657\|ref\|ZP_00796753.1\| COG0760: Parvulin-like peptidyl-prolyl isomerase [Yersinia pestis Ang...	321.0	[0..1]	[427..1]
gi\|66047852, gi\|... - gi\|66047852\|ref\|YP_237693.1\| PpiC-type peptidyl-prolyl cis-trans isomerase [Pseudomonas syringae pv....	319.0	[0..4]	[426..11]
SURA_PHOLL - Chaperone SurA OS=Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01) G... SURA_PHOLL - Chaperone surA OS=Photorhabdus luminescens subsp. laumondii GN=surA PE=3 SV=1	318.0	[0..1]	[427..1]

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Predicted Domain #1

Region A:
Residues: [1-428]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKNWKTLLLG IAMIANTSFA APQVVDKVAA VVNNGVVLES DVDGLMQSVK LNAAQARQQL  60
   61 PDDATLRHQI MERLIMDQII LQMGQKMGVK ISDEQLDQAI ANIAKQNNMT LDQMRSRLAY 120
  121 DGLNYNTYRN QIRKEMIISE VRNNEVRRRI TILPQEVESL AQQVGNQNDA STELNLSHIL 180
  181 IPLPENPTSD QVNEAESQAR AIVDQARNGA DFGKLAIAHS ADQQALNGGQ MGWGRIQELP 240
  241 GIFAQALSTA KKGDIVGPIR SGVGFHILKV NDLRGESKNI SVTEVHARHI LLKPSPIMTD 300
  301 EQARVKLEQI AADIKSGKTT FAAAAKEFSQ DPGSANQGGD LGWATPDIFD PAFRDALTRL 360
  361 NKGQMSAPVH SSFGWHLIEL LDTRNVDKTD AAQKDRAYRM LMNRKFSEEA ASWMQEQRAS 420
  421 AYVKILSN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	76.154902
Match:	1m5yA
Description:	Porin chaperone SurA, peptide-binding domain; Porin chaperone SurA, PPIase domains
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
peptidyl-prolyl cis-trans isomerase activity	4.4182664267098	bayes_pls_golite062009
cis-trans isomerase activity	4.33661522951196	bayes_pls_golite062009
isomerase activity	2.83057106437196	bayes_pls_golite062009
macrolide binding	1.34183721806994	bayes_pls_golite062009
catalytic activity	1.25572252987503	bayes_pls_golite062009
FK506 binding	1.11705415888427	bayes_pls_golite062009
binding	0.863342313564958	bayes_pls_golite062009
transcription regulator activity	0.623063015282266	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: