YRC Public Data Repository - Protein Structure Prediction

Protein:	SPED_ECOLI
Organism:	Escherichia coli
Length:	264 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPED_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|192955451, gi... - gi\|75233847\|ref\|ZP_00718317.1\| COG1586: S-adenosylmethionine decarboxylase [Escherichia coli E110019...	439.0	[0..1]	[264..1]
SPED_ECOUT - S-adenosylmethionine decarboxylase proenzyme OS=Escherichia coli (strain UTI89 / UPEC) GN=speD PE=3 ... SPED_ECOL5 - S-adenosylmethionine decarboxylase proenzyme OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=s... SPED_ECO45 - S-adenosylmethionine decarboxylase proenzyme OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=speD... gi\|227884969, gi... - gi\|227884969\|ref\|ZP_04002774.1\| S-adenosylmethionine decarboxylase [Escherichia coli 83972], gi\|2278... gi\|226902188, gi... - gi\|237704276\|ref\|ZP_04534757.1\| adenosylmethionine decarboxylase [Escherichia sp. 3_2_53FAA], gi\|226... gi\|190906899, gi... - gi\|75240288\|ref\|ZP_00724235.1\| COG1586: S-adenosylmethionine decarboxylase [Escherichia coli F11], g... SPED_ECOL6 - S-adenosylmethionine decarboxylase proenzyme OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 ... SPED_ECOL6 - S-adenosylmethionine decarboxylase proenzyme OS=Escherichia coli O6 GN=speD PE=3 SV=1	438.0	[0..1]	[264..1]
SPED_SHIDS - S-adenosylmethionine decarboxylase proenzyme OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=sp...	438.0	[0..1]	[264..1]
gi\|77957549, gi\|... - gi\|77957549\|ref\|ZP_00821602.1\| COG1586: S-adenosylmethionine decarboxylase [Yersinia bercovieri ATCC...	437.0	[0..1]	[264..1]
gi\|238786760, gi... - gi\|77976065\|ref\|ZP_00831598.1\| COG1586: S-adenosylmethionine decarboxylase [Yersinia frederiksenii A...	437.0	[0..1]	[264..1]
SPED_SALDC - S-adenosylmethionine decarboxylase proenzyme OS=Salmonella dublin (strain CT_02021853) GN=speD PE=3 ... SPED_SALPK - S-adenosylmethionine decarboxylase proenzyme OS=Salmonella paratyphi A (strain AKU_12601) GN=speD PE... SPED_SALPA - S-adenosylmethionine decarboxylase proenzyme OS=Salmonella paratyphi A GN=speD PE=3 SV=1 SPED_SALPA - S-adenosylmethionine decarboxylase proenzyme OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) G... SPED_SALEP - S-adenosylmethionine decarboxylase proenzyme OS=Salmonella enteritidis PT4 (strain P125109) GN=speD ...	436.0	[0..1]	[264..1]
gi\|166204721, gi... - gi\|166214090\|ref\|ZP_02240125.1\| S-adenosylmethionine decarboxylase proenzyme [Yersinia pestis biovar... gi\|167399403, gi... - gi\|167399403\|ref\|ZP_02304927.1\| S-adenosylmethionine decarboxylase proenzyme [Yersinia pestis biovar... gi\|167420698, gi... - gi\|167420698\|ref\|ZP_02312451.1\| S-adenosylmethionine decarboxylase proenzyme [Yersinia pestis biovar... gi\|167057631, gi... - gi\|167423461\|ref\|ZP_02315214.1\| S-adenosylmethionine decarboxylase proenzyme [Yersinia pestis biovar... SPED_YERPY - S-adenosylmethionine decarboxylase proenzyme OS=Yersinia pseudotuberculosis serotype O:3 (strain YPI... SPED_YERPB - S-adenosylmethionine decarboxylase proenzyme OS=Yersinia pseudotuberculosis serotype IB (strain PB1/... gi\|22124687, gi\|... - gi\|22124687\|ref\|NP_668110.1\| S-adenosylmethionine decarboxylase [Yersinia pestis KIM], gi\|21957500\|g... gi\|218930429, gi... - gi\|218930429\|ref\|YP_002348304.1\| S-adenosylmethionine decarboxylase [Yersinia pestis CO92], gi\|16123... SPED_YERPN - S-adenosylmethionine decarboxylase proenzyme OS=Yersinia pestis bv. Antiqua (strain Nepal516) GN=spe... gi\|45440133, gi\|... - gi\|45440133\|ref\|NP_991672.1\| S-adenosylmethionine decarboxylase [Yersinia pestis biovar Microtus str... SPED_YERPE - S-adenosylmethionine decarboxylase proenzyme OS=Yersinia pestis GN=speD PE=3 SV=1 gi\|165936771, gi... - gi\|89104446\|ref\|ZP_01176989.1\| COG1586: S-adenosylmethionine decarboxylase [Yersinia pestis biovar O... gi\|165922459, gi... - gi\|165925847\|ref\|ZP_02221679.1\| S-adenosylmethionine decarboxylase proenzyme [Yersinia pestis biovar... gi\|229899616, gi... - gi\|229899616\|ref\|ZP_04514757.1\| S-adenosylmethionine decarboxylase [Yersinia pestis biovar Orientali... SPED_YERPA - S-adenosylmethionine decarboxylase proenzyme OS=Yersinia pestis bv. Antiqua (strain Antiqua) GN=speD... gi\|165990930, gi... - gi\|166010023\|ref\|ZP_02230921.1\| S-adenosylmethionine decarboxylase proenzyme [Yersinia pestis biovar... gi\|229700604, gi... - gi\|229896530\|ref\|ZP_04511698.1\| S-adenosylmethionine decarboxylase [Yersinia pestis Pestoides A], gi... gi\|229839051, gi... - gi\|229839051\|ref\|ZP_04459210.1\| S-adenosylmethionine decarboxylase [Yersinia pestis biovar Orientali... SPED_YERPG - S-adenosylmethionine decarboxylase proenzyme OS=Yersinia pestis bv. Antiqua (strain Angola) GN=speD ... SPED_YERPP - S-adenosylmethionine decarboxylase proenzyme OS=Yersinia pestis (strain Pestoides F) GN=speD PE=3 SV... SPED_YERP3 - S-adenosylmethionine decarboxylase proenzyme OS=Yersinia pseudotuberculosis serotype O:1b (strain IP... gi\|149289182, gi... - gi\|153997545\|ref\|ZP_02022645.1\| S-adenosylmethionine decarboxylase proenzyme [Yersinia pestis CA88-4...	435.0	[0..1]	[264..1]
gi\|29140711, gi\|... - gi\|29140711\|ref\|NP_804053.1\| S-adenosylmethionine decarboxylase [Salmonella enterica subsp. enterica... gi\|16759161 - gi\|16759161\|ref\|NP_454778.1\| S-adenosylmethionine decarboxylase [Salmonella enterica subsp. enterica... gi\|200388020, gi... - gi\|200388020\|ref\|ZP_03214632.1\| S-adenosylmethionine decarboxylase proenzyme [Salmonella enterica su... gi\|213160903 - gi\|213160903\|ref\|ZP_03346613.1\| S-adenosylmethionine decarboxylase [Salmonella enterica subsp. enter... SPED_SALTI - S-adenosylmethionine decarboxylase proenzyme OS=Salmonella typhi GN=speD PE=3 SV=1 gi\|213419813 - gi\|213419813\|ref\|ZP_03352879.1\| S-adenosylmethionine decarboxylase [Salmonella enterica subsp. enter... SPED_SALTI - S-adenosylmethionine decarboxylase proenzyme OS=Salmonella typhi GN=speD PE=3 SV=1 gi\|213426711 - gi\|213426711\|ref\|ZP_03359461.1\| S-adenosylmethionine decarboxylase [Salmonella enterica subsp. enter... gi\|213581308 - gi\|213581308\|ref\|ZP_03363134.1\| S-adenosylmethionine decarboxylase [Salmonella enterica subsp. enter... gi\|213857399 - gi\|213857399\|ref\|ZP_03384370.1\| S-adenosylmethionine decarboxylase [Salmonella enterica subsp. enter... gi\|214000728 - gi\|214000728\|ref\|ZP_03411463.1\| S-adenosylmethionine decarboxylase [Salmonella enterica subsp. enter...	435.0	[0..1]	[264..1]
SPED_SODGM - S-adenosylmethionine decarboxylase proenzyme OS=Sodalis glossinidius (strain morsitans) GN=speD PE=3...	435.0	[0..1]	[264..1]
SPED_SALCH - S-adenosylmethionine decarboxylase proenzyme OS=Salmonella choleraesuis (strain SC-B67) GN=speD PE=3... SPED_SALCH - S-adenosylmethionine decarboxylase proenzyme OS=Salmonella choleraesuis GN=speD PE=3 SV=1 SPED_SALCH - S-adenosylmethionine decarboxylase proenzyme OS=Salmonella choleraesuis GN=speD PE=3 SV=1	435.0	[0..1]	[264..1]

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Predicted Domain #1

Region A:
Residues: [1-169]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKLKLHGFN NLTKSLSFCI YDICYAKTAE ERDGYIAYID ELYNANRLTE ILSETCSIIG  60
   61 ANILNIARQD YEPQGASVTI LVSEEPVDPK LIDKTEHPGP LPETVVAHLD KSHICVHTYP 120
  121 ESHPEGGLCT FRADIEVSTC GVISPLKALN YLIHQLESDI VTIDYRVRG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	24.522879
Match:	1vr7A
Description:	Crystal structure of S-adenosylmethionine decarboxylase proenzyme (TM0655) from THERMOTOGA MARITIMA at 1.2 A resolution
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [170-264]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FTRDINGMKH FIDHEINSIQ NFMSDDMKAL YDMVDVNVYQ ENIFHTKMLL KEFDLKHYMF  60
   61 HTKPEDLTDS ERQEITAALW KEMREIYYGR NMPAV

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits