YRC Public Data Repository - Protein Structure Prediction

Protein:	SDIA_ECOLI
Organism:	Escherichia coli
Length:	240 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SDIA_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|196252895, gi... - gi\|196252895\|ref\|ZP_03151542.1\| two component transcriptional regulator, LuxR family [Clostridium th... gi\|67873312, gi\|... - gi\|67873312\|ref\|ZP_00503591.1\| regulatory protein, LuxR:Response regulator receiver [Clostridium the...	176.0	[0..14]	[239..3]
gi\|228791148, gi... - gi\|228968544\|ref\|ZP_04129531.1\| Two component transcriptional regulator, LuxR [Bacillus thuringiensi... gi\|228903890, gi... - gi\|228903890\|ref\|ZP_04068005.1\| Two component transcriptional regulator, LuxR [Bacillus thuringiensi... gi\|75760127, gi\|... - gi\|75760127\|ref\|ZP_00740188.1\| Two-component response regulator yhcZ [Bacillus thuringiensis serovar... gi\|218542579, gi... - gi\|218900537\|ref\|YP_002448948.1\| DNA-binding response regulator [Bacillus cereus G9842], gi\|21854257...	171.0	[0..13]	[240..1]
gi\|53688577 - gi\|53688577\|ref\|ZP_00110736.2\| COG2197: Response regulator containing a CheY-like receiver domain an...	171.0	[0..15]	[234..2]
gi\|42784585, gi\|... - gi\|42784585\|ref\|NP_981832.1\| DNA-binding response regulator [Bacillus cereus ATCC 10987], gi\|4274051...	170.0	[0..13]	[240..1]
gi\|229147955, gi... - gi\|229147955\|ref\|ZP_04276296.1\| Two component transcriptional regulator, LuxR [Bacillus cereus BDRD-... gi\|229130659, gi... - gi\|229130659\|ref\|ZP_04259615.1\| Two component transcriptional regulator, LuxR [Bacillus cereus BDRD-... gi\|228670658, gi... - gi\|229112824\|ref\|ZP_04242356.1\| Two component transcriptional regulator, LuxR [Bacillus cereus Rock1... gi\|30023441, gi\|... - gi\|30023441\|ref\|NP_835072.1\| two-component response regulator yhcZ [Bacillus cereus ATCC 14579], gi\|... gi\|229051082, gi... - gi\|229051082\|ref\|ZP_04194629.1\| Two component transcriptional regulator, LuxR [Bacillus cereus AH676... gi\|228798024, gi... - gi\|228961674\|ref\|ZP_04123282.1\| Two component transcriptional regulator, LuxR [Bacillus thuringiensi...	170.0	[0..13]	[240..1]
gi\|21397894, gi\|... - gi\|65317392\|ref\|ZP_00390351.1\| COG2197: Response regulator containing a CheY-like receiver domain an... gi\|225787376, gi... - gi\|225867394\|ref\|YP_002752772.1\| DNA-binding response regulator [Bacillus cereus 03BB102], gi\|225787... gi\|227818179, gi... - gi\|227818179\|ref\|YP_002818188.1\| DNA-binding response regulator [Bacillus anthracis str. CDC 684], g... gi\|228841613, gi... - gi\|228918025\|ref\|ZP_04081555.1\| Two component transcriptional regulator, LuxR [Bacillus thuringiensi... gi\|52145220, gi\|... - gi\|52145220\|ref\|YP_086677.1\| response regulator [Bacillus cereus E33L], gi\|51978689\|gb\|AAU20239.1\| r... gi\|228930420, gi... - gi\|228930420\|ref\|ZP_04093421.1\| Two component transcriptional regulator, LuxR [Bacillus thuringiensi... gi\|228822907, gi... - gi\|228936698\|ref\|ZP_04099489.1\| Two component transcriptional regulator, LuxR [Bacillus thuringiensi... gi\|49182175, gi\|... - gi\|49188248\|ref\|YP_031501.1\| DNA-binding response regulator [Bacillus anthracis str. Sterne], gi\|491... gi\|228810578, gi... - gi\|228949137\|ref\|ZP_04111407.1\| Two component transcriptional regulator, LuxR [Bacillus thuringiensi... gi\|49481286, gi\|... - gi\|49481286\|ref\|YP_039401.1\| response regulator [Bacillus thuringiensis serovar konkukian str. 97-27... gi\|229124916, gi... - gi\|229124916\|ref\|ZP_04254092.1\| Two component transcriptional regulator, LuxR [Bacillus cereus 95/82... gi\|30260110, gi\|... - gi\|30265432\|ref\|NP_847809.1\| DNA-binding response regulator [Bacillus anthracis str. Ames], gi\|30260... gi\|229187641, gi... - gi\|229187641\|ref\|ZP_04314778.1\| Two component transcriptional regulator, LuxR [Bacillus cereus BGSC ... gi\|47530989, gi\|... - gi\|47530989\|ref\|YP_022338.1\| DNA-binding response regulator [Bacillus anthracis str. 'Ames Ancestor'... gi\|229603380, gi... - gi\|229603380\|ref\|YP_002869624.1\| DNA-binding response regulator [Bacillus anthracis str. A0248], gi\|... gi\|196045422, gi... - gi\|196045422\|ref\|ZP_03112653.1\| DNA-binding response regulator [Bacillus cereus 03BB108], gi\|1960236... gi\|254687146 - gi\|254687146\|ref\|ZP_05151004.1\| DNA-binding response regulator [Bacillus anthracis str. CNEVA-9066] gi\|196041030, gi... - gi\|196041030\|ref\|ZP_03108327.1\| DNA-binding response regulator [Bacillus cereus NVH0597-99], gi\|1960... gi\|254724071 - gi\|254724071\|ref\|ZP_05185856.1\| DNA-binding response regulator [Bacillus anthracis str. A1055] gi\|254735533 - gi\|254735533\|ref\|ZP_05193240.1\| DNA-binding response regulator [Bacillus anthracis str. Western Nort... gi\|218906592, gi... - gi\|218906592\|ref\|YP_002454426.1\| DNA-binding response regulator [Bacillus cereus AH820], gi\|21853732... gi\|254742202 - gi\|254742202\|ref\|ZP_05199889.1\| DNA-binding response regulator [Bacillus anthracis str. Kruger B] gi\|254755887 - gi\|254755887\|ref\|ZP_05207919.1\| DNA-binding response regulator [Bacillus anthracis str. Vollum] gi\|254761599 - gi\|254761599\|ref\|ZP_05213619.1\| DNA-binding response regulator [Bacillus anthracis str. Australia 94... gi\|167635732, gi... - gi\|167635732\|ref\|ZP_02394042.1\| DNA-binding response regulator [Bacillus anthracis str. A0442], gi\|1... gi\|165871317, gi... - gi\|165871317\|ref\|ZP_02215966.1\| DNA-binding response regulator [Bacillus anthracis str. A0488], gi\|1... gi\|170667905, gi... - gi\|170688212\|ref\|ZP_02879423.1\| DNA-binding response regulator [Bacillus anthracis str. A0465], gi\|1... gi\|167511651, gi... - gi\|167640431\|ref\|ZP_02398695.1\| DNA-binding response regulator [Bacillus anthracis str. A0193], gi\|1... gi\|172082659, gi... - gi\|177651955\|ref\|ZP_02934538.1\| DNA-binding response regulator [Bacillus anthracis str. A0174], gi\|1... gi\|170708051, gi... - gi\|170708051\|ref\|ZP_02898499.1\| DNA-binding response regulator [Bacillus anthracis str. A0389], gi\|1... gi\|195991317, gi... - gi\|196036150\|ref\|ZP_03103550.1\| DNA-binding response regulator [Bacillus cereus W], gi\|195991317\|gb\|... gi\|190568889, gi... - gi\|190568889\|ref\|ZP_03021791.1\| DNA-binding response regulator [Bacillus anthracis Tsiankovskii-I], ... gi\|118480442, gi... - gi\|118480442\|ref\|YP_897593.1\| DNA-binding response regulator [Bacillus thuringiensis str. Al Hakam],...	169.0	[0..13]	[240..1]
gi\|229065062, gi... - gi\|229065062\|ref\|ZP_04200357.1\| Two component transcriptional regulator, LuxR [Bacillus cereus AH603... gi\|229014574, gi... - gi\|229014574\|ref\|ZP_04171690.1\| Two component transcriptional regulator, LuxR [Bacillus mycoides DSM... gi\|228613347, gi... - gi\|229170116\|ref\|ZP_04297805.1\| Two component transcriptional regulator, LuxR [Bacillus cereus AH621... gi\|89205956, gi\|... - gi\|89205956\|ref\|ZP_01184521.1\| regulatory protein, LuxR:Response regulator receiver [Bacillus weihen... gi\|228647209, gi... - gi\|229136229\|ref\|ZP_04264978.1\| Two component transcriptional regulator, LuxR [Bacillus cereus BDRD-...	169.0	[0..13]	[240..1]
gi\|219994325, gi... - gi\|89209594\|ref\|ZP_01187989.1\| regulatory protein, LuxR:Response regulator receiver [Halothermothrix...	169.0	[0..16]	[240..5]
gi\|94984662, gi\|... - gi\|94984662\|ref\|YP_604026.1\| two component LuxR family transcriptional regulator [Deinococcus geothe...	169.0	[0..1]	[240..1]
gi\|47557254, gi\|... - gi\|47565618\|ref\|ZP_00236658.1\| MW1789 [Bacillus cereus G9241], gi\|47557254\|gb\|EAL15582.1\| MW1789 [Ba...	169.0	[0..13]	[238..1]

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Predicted Domain #1

Region A:
Residues: [1-141]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQDKDFFSWR RTMLLRFQRM ETAEEVYHEI ELQAQQLEYD YYSLCVRHPV PFTRPKVAFY  60
   61 TNYPEAWVSY YQAKNFLAID PVLNPENFSQ GHLMWNDDLF SEAQPLWEAA RAHGLRRGVT 120
  121 QYLMLPNRAL GFLSFSRCSA R

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	5.221849
Match:	2avxA
Description:	No description for 2avxA was found.

Predicted Domain #2

Region A:
Residues: [142-240]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EIPILSDELQ LKMQLLVRES LMALMRLNDE IVMTPEMNFS KREKEILRWT AEGKTSAEIA  60
   61 MILSISENTV NFHQKNMQKK INAPNKTQVA CYAAATGLI

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	4.34
Match:	1p4wA
Description:	Transcriptional regulator RcsB
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	4.02482454658958	bayes_pls_golite062009
DNA binding	2.72249603154098	bayes_pls_golite062009
nucleic acid binding	2.67990662898614	bayes_pls_golite062009
transcription factor activity	2.29206921767469	bayes_pls_golite062009
binding	1.74241874015133	bayes_pls_golite062009
signal transducer activity	1.15368237557094	bayes_pls_golite062009
molecular transducer activity	1.15368237557094	bayes_pls_golite062009
two-component response regulator activity	1.04875199183902	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: