YRC Public Data Repository - Protein Structure Prediction

Protein:	SBCC_ECOLI
Organism:	Escherichia coli
Length:	1048 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SBCC_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|94369992 - gi\|94369992\|ref\|XP_979429.1\| PREDICTED: similar to SMC4 structural maintenance of chromosomes 4-like...	210.0	[0..3]	[952..214]
gi\|253774618, gi... - gi\|254287267\|ref\|YP_003053015.1\| exonuclease, dsDNA, ATP-dependent [Escherichia coli BL21(DE3)], gi\|... gi\|242376175, gi... - gi\|251783902\|ref\|YP_002998206.1\| hypothetical protein B21_00349 [Escherichia coli BL21], gi\|24237617... gi\|83585684, gi\|... - gi\|83585684\|ref\|ZP_00924326.1\| COG0419: ATPase involved in DNA repair [Escherichia coli 101-1], gi\|1... gi\|253972365, gi... - gi\|254160464\|ref\|YP_003043572.1\| exonuclease, dsDNA, ATP-dependent [Escherichia coli B str. REL606],...	206.0	[0..1]	[1048..1]
gi\|218552959, gi... - gi\|218552959\|ref\|YP_002385872.1\| exonuclease subunit SbcC [Escherichia coli IAI1], gi\|218359727\|emb\|... gi\|218350589, gi... - gi\|218693857\|ref\|YP_002401524.1\| exonuclease subunit SbcC [Escherichia coli 55989], gi\|218350589\|emb... gi\|169756159, gi... - gi\|170021231\|ref\|YP_001726185.1\| exonuclease subunit SbcC [Escherichia coli ATCC 8739], gi\|169756159... gi\|209910867, gi... - gi\|209917608\|ref\|YP_002291692.1\| exonuclease subunit SbcC [Escherichia coli SE11], gi\|209910867\|dbj\|... gi\|188491739, gi... - gi\|75512458\|ref\|ZP_00734997.1\| COG0419: ATPase involved in DNA repair [Escherichia coli 53638], gi\|1... gi\|192927183, gi... - gi\|75256769\|ref\|ZP_00728374.1\| COG0419: ATPase involved in DNA repair [Escherichia coli E22], gi\|193... gi\|75209953, gi\|... - gi\|75209953\|ref\|ZP_00710142.1\| COG0419: ATPase involved in DNA repair [Escherichia coli B171], gi\|19... gi\|157065594, gi... - gi\|75194616\|ref\|ZP_00704686.1\| COG0419: ATPase involved in DNA repair [Escherichia coli HS], gi\|1571... gi\|124500229, gi... - gi\|124528892\|ref\|ZP_01700077.1\| exonuclease SbcC [Escherichia coli B], gi\|124500229\|gb\|EAY47705.1\| e...	204.0	[0..1]	[1048..1]
gi\|110613968, gi... - gi\|110804420\|ref\|YP_687940.1\| exonuclease subunit SbcC [Shigella flexneri 5 str. 8401], gi\|110613968...	203.0	[0..1]	[1048..1]
gi\|110342250, gi... - gi\|110640658\|ref\|YP_668386.1\| exonuclease subunit SbcC [Escherichia coli 536], gi\|110342250\|gb\|ABG68... gi\|190906212, gi... - gi\|75238724\|ref\|ZP_00722712.1\| COG0419: ATPase involved in DNA repair [Escherichia coli F11], gi\|191...	203.0	[0..1]	[1048..1]
gi\|30061893, gi\|... - gi\|30061893\|ref\|NP_836064.1\| exonuclease subunit SbcC [Shigella flexneri 2a str. 2457T], gi\|30040137... gi\|24050561, gi\|... - gi\|24111775\|ref\|NP_706285.1\| exonuclease subunit SbcC [Shigella flexneri 2a str. 301], gi\|24050561\|g...	203.0	[0..1]	[1048..1]
gi\|193068718, gi... - gi\|75237222\|ref\|ZP_00721269.1\| COG0419: ATPase involved in DNA repair [Escherichia coli E110019], gi...	203.0	[0..1]	[1048..1]
gi\|74310966, gi\|... - gi\|74310966\|ref\|YP_309385.1\| exonuclease subunit SbcC [Shigella sonnei Ss046], gi\|73854443\|gb\|AAZ871...	203.0	[0..1]	[1048..1]
gi\|26246400, gi\|... - gi\|26246400\|ref\|NP_752439.1\| exonuclease subunit SbcC [Escherichia coli CFT073], gi\|26106798\|gb\|AAN7...	202.0	[0..1]	[1048..1]
gi\|91209463, gi\|... - gi\|91209463\|ref\|YP_539449.1\| exonuclease subunit SbcC [Escherichia coli UTI89], gi\|91071037\|gb\|ABE05... gi\|117622658, gi... - gi\|117622658\|ref\|YP_851571.1\| exonuclease subunit SbcC [Escherichia coli APEC O1], gi\|115511782\|gb\|A... gi\|226898821, gi... - gi\|237707611\|ref\|ZP_04538092.1\| exonuclease subunit SbcC [Escherichia sp. 3_2_53FAA], gi\|226898821\|g... gi\|218557306, gi... - gi\|218557306\|ref\|YP_002390219.1\| exonuclease subunit SbcC [Escherichia coli S88], gi\|218364075\|emb\|C...	202.0	[0..1]	[1048..1]

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Predicted Domain #1

Region A:
Residues: [1-277]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKILSLRLKN LNSLKGEWKI DFTREPFASN GLFAITGPTG AGKTTLLDAI CLALYHETPR  60
   61 LSNVSQSQND LMTRDTAECL AEVEFEVKGE AYRAFWSQNR ARNQPDGNLQ VPRVELARCA 120
  121 DGKILADKVK DKLELTATLT GLDYGRFTRS MLLSQGQFAA FLNAKPKERA ELLEELTGTE 180
  181 IYGQISAMVF EQHKSARTEL EKLQAQASGV TLLTPEQVQS LTASLQVLTD EEKQLITAQQ 240
  241 QEQQSLNWLT RQDELQQEAS RRQQALQQAL AEEEKAQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	16.69897
Match:	1w1wA
Description:	Sc Smc1hd:Scc1-C complex, ATPgS
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.470983068319171	bayes_pls_golite062009
hydrolase activity	0.0582794297634999	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [278-494]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PQLAALSLAQ PARNLRPHWE RIAEHSAALA HIRQQIEEVN TRLQSTMALR ASIRHHAAKQ  60
   61 SAELQQQQQS LNTWLQEHDR FRQWNNEPAG WRAQFSQQTS DREHLRQWQQ QLTHAEQKLN 120
  121 ALAAITLTLT ADEVATALAQ HAEQRPLRQH LVALHGQIVP QQKRLAQLQV AIQNVTQEQT 180
  181 QRNAALNEMR QRYKEKTQQL ADVKTICEQE ARIKTLE

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [495-838]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AQRAQLQAGQ PCPLCGSTSH PAVEAYQALE PGVNQSRLLA LENEVKKLGE EGATLRGQLD  60
   61 AITKQLQRDE NEAQSLRQDE QALTQQWQAV TASLNITLQP LDDIQPWLDA QDEHERQLRL 120
  121 LSQRHELQGQ IAAHNQQIIQ YQQQIEQRQQ LLLTTLTGYA LTLPQEDEEE SWLATRQQEA 180
  181 QSWQQRQNEL TALQNRIQQL TPILETLPQS DELPHCEETV VLENWRQVHE QCLALHSQQQ 240
  241 TLQQQDVLAA QSLQKAQAQF DTALQASVFD DQQAFLAALM DEQTLTQLEQ LKQNLENQRR 300
  301 QAQTLVTQTA ETLAQHQQHR PDDGLALTVT VEQIQQELAQ THQK

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	2.11
Match:	1c1gA
Description:	Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #4

Region A:
Residues: [839-1048]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LRENTTSQGE IRQQLKQDAD NRQQQQTLMQ QIAQMTQQVE DWGYLNSLIG SKEGDKFRKF  60
   61 AQGLTLDNLV HLANQQLTRL HGRYLLQRKA SEALEVEVVD TWQADAVRDT RTLSGGESFL 120
  121 VSLALALALS DLVSHKTRID SLFLDEGFGT LDSETLDTAL DALDALNASG KTIGVISHVE 180
  181 AMKERIPVQI KVKKINGLGY SKLESTFAVK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	13.0
Match:	1f3oA
Description:	MJ0796
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.470983068319171	bayes_pls_golite062009
hydrolase activity	0.0582794297634999	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: