YRC Public Data Repository - Protein Structure Prediction

Protein:	RLMB_PASMU
Organism:	Pasteurella multocida
Length:	245 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RLMB_PASMU.

Description	E-value	Query Range	Subject Range
gi\|52424529, gi\|... - gi\|52424529\|ref\|YP_087666.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Mannheimia succiniciprodu...	262.0	[0..1]	[245..1]
RLMB_HAEIN - 23S rRNA (guanosine-2'-O-)-methyltransferase rlmB OS=Haemophilus influenzae GN=rlmB PE=1 SV=1 gi\|148716655, gi... - gi\|148826495\|ref\|YP_001291248.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Haemophilus influenza... gi\|229812452, gi... - gi\|229844738\|ref\|ZP_04464877.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Haemophilus influenzae... gi\|145267883, gi... - gi\|145634717\|ref\|ZP_01790425.1\| hypothetical protein CGSHiAA_03913 [Haemophilus influenzae PittAA], ... gi\|144987136, gi... - gi\|145632229\|ref\|ZP_01787964.1\| hypothetical protein CGSHi3655_07239 [Haemophilus influenzae 3655], ... gi\|229845912, gi... - gi\|229845912\|ref\|ZP_04466024.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Haemophilus influenzae... RLMB_HAEIN - 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB OS=Haemophilus influenzae (strain ATCC 51907 / DSM...	262.0	[0..1]	[244..1]
gi\|145638336, gi... - gi\|145638336\|ref\|ZP_01793946.1\| hypothetical protein CGSHiII_06179 [Haemophilus influenzae PittII], ... gi\|145628238, gi... - gi\|145628238\|ref\|ZP_01784039.1\| hypothetical protein CGSHi22121_04335 [Haemophilus influenzae 22.1-2... gi\|46133163 - gi\|46133163\|ref\|ZP_00156715.2\| COG0566: rRNA methylases [Haemophilus influenzae R2866]	261.0	[0..1]	[244..1]
gi\|32033775 - gi\|32033775\|ref\|ZP_00134060.1\| COG0566: rRNA methylases [Actinobacillus pleuropneumoniae serovar 1 s... gi\|165975500, gi... - gi\|165975500\|ref\|YP_001651093.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Actinobacillus pleuro... gi\|189914442, gi... - gi\|190149311\|ref\|YP_001967836.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Actinobacillus pleuro... gi\|126096322, gi... - gi\|126207530\|ref\|YP_001052755.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Actinobacillus pleuro...	261.0	[0..1]	[245..1]
gi\|42630311 - gi\|42630311\|ref\|ZP_00155855.1\| COG0566: rRNA methylases [Haemophilus influenzae R2846]	260.0	[0..1]	[244..1]
gi\|25316695 - pir\|\|A83664 tRNA/rRNA methyltransferase BH0113 [imported] - Bacillus halodurans (strain C-125) gi\|15612676, gi\|... - gi\|15612676\|ref\|NP_240979.1\| tRNA/rRNA methyltransferase [Bacillus halodurans C-125], gi\|10172725\|db...	259.0	[0..3]	[244..4]
gi\|68249454, gi\|... - gi\|68249454\|ref\|YP_248566.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Haemophilus influenzae 86...	259.0	[0..1]	[244..1]
RLMB_HAEDU - 23S rRNA (guanosine-2'-O-)-methyltransferase rlmB OS=Haemophilus ducreyi GN=rlmB PE=3 SV=1 RLMB_HAEDU - 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB OS=Haemophilus ducreyi (strain 35000HP / ATCC 7007...	258.0	[0..1]	[245..1]
gi\|74275782, gi\|... - gi\|75437665\|ref\|ZP_00733474.1\| rRNA methylases [Actinobacillus succinogenes 130Z], gi\|74275782\|gb\|EA...	257.0	[0..1]	[245..1]
gi\|46156114, gi\|... - gi\|46156114\|ref\|ZP_00133380.2\| COG0566: rRNA methylases [Haemophilus somnus 2336], gi\|170718084\|ref\|... gi\|23467939, gi\|... - gi\|23467939\|ref\|ZP_00123515.1\| COG0566: rRNA methylases [Haemophilus somnus 129PT], gi\|113460298\|ref...	255.0	[0..1]	[244..1]

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Predicted Domain #1

Region A:
Residues: [1-245]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSENIYGIHA VSAFLNNAPE RLIEVYALKG RDDKRLQPLL NELHRLGITI QFVNRQTLDK  60
   61 KAEGEVHQGI MARVQPAKEL NEADLDTLLQ NQSNPLLLVL DGVTDPHNLG ACLRTADAAG 120
  121 VCAVIVPKDK SAQLTAIARK VACGAAEVVP LIRVTNLART LRELQQKHNI WVVGTAGEAT 180
  181 NTLYQTQLTG GLALVMGAEG EGMRRLTREH CDQLISIPMA GSVSSLNVSV ATGVCLFEIV 240
  241 RQRLA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	67.154902
Match:	1gz0A
Description:	RlmB, C-terminal domain; RlmB, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
RNA methyltransferase activity	4.23455016472464	bayes_pls_golite062009
methyltransferase activity	3.59960278169345	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	3.51722801996622	bayes_pls_golite062009
rRNA methyltransferase activity	3.14976989427746	bayes_pls_golite062009
tRNA methyltransferase activity	2.33123191403389	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	2.23755555119187	bayes_pls_golite062009
tRNA (guanine) methyltransferase activity	2.14623472760939	bayes_pls_golite062009
transferase activity	1.63934797352054	bayes_pls_golite062009
structural constituent of ribosome	1.0137045454994	bayes_pls_golite062009
catalytic activity	0.797300463760338	bayes_pls_golite062009
N-methyltransferase activity	0.736216022000293	bayes_pls_golite062009
structural molecule activity	0.694233763389628	bayes_pls_golite062009
binding	0.650146274744039	bayes_pls_golite062009
nucleic acid binding	0.404179021204849	bayes_pls_golite062009
rRNA (guanine) methyltransferase activity	0.319046095835882	bayes_pls_golite062009
	0.16936231012632	bayes_pls_golite062009
snoRNA binding	0.155192244522672	bayes_pls_golite062009
protein binding	0.031057919963412	bayes_pls_golite062009
rRNA (guanine-N1-)-methyltransferase activity	6.26422903788337E-4	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: