YRC Public Data Repository - Protein Structure Prediction

Protein:	RCSB_ECOLX
Organism:	Escherichia coli
Length:	216 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RCSB_ECOLX.

Description	E-value	Query Range	Subject Range
gi\|86739037, gi\|... - gi\|86739037\|ref\|YP_479437.1\| two component transcriptional regulator [Frankia sp. CcI3], gi\|86565899...	184.0	[0..1]	[216..156]
gi\|111220170, gi... - gi\|111220170\|ref\|YP_710964.1\| putative two-component system response regulator (partial match) [Fran...	183.0	[0..1]	[216..16]
gi\|52784773, gi\|... - gi\|52784773\|ref\|YP_090602.1\| YhcZ [Bacillus licheniformis ATCC 14580], gi\|52347275\|gb\|AAU39909.1\| Yh...	182.0	[0..1]	[210..1]
gi\|42780487, gi\|... - gi\|42780487\|ref\|NP_977734.1\| DNA-binding response regulator [Bacillus cereus ATCC 10987], gi\|4273640... gi\|222095033, gi... - gi\|222095033\|ref\|YP_002529093.1\| response regulator [Bacillus cereus Q1], gi\|221239091\|gb\|ACM11801.1... gi\|217068126, gi... - gi\|217958874\|ref\|YP_002337422.1\| DNA-binding response regulator [Bacillus cereus AH187], gi\|21706812... gi\|206977570, gi... - gi\|206977570\|ref\|ZP_03238464.1\| DNA-binding response regulator [Bacillus cereus H3081.97], gi\|206744...	181.0	[0..1]	[213..1]
gi\|219994325, gi... - gi\|89209594\|ref\|ZP_01187989.1\| regulatory protein, LuxR:Response regulator receiver [Halothermothrix...	181.0	[0..1]	[211..1]
gi\|163939206, gi... - gi\|89204474\|ref\|ZP_01183051.1\| Response regulator receiver:Transcriptional regulatory protein, C-ter...	181.0	[0..1]	[213..1]
gi\|47556738, gi\|... - gi\|47566185\|ref\|ZP_00237213.1\| two-component response regulator [Bacillus cereus G9241], gi\|47556738...	180.0	[0..1]	[213..1]
gi\|225785753, gi... - gi\|225863261\|ref\|YP_002748639.1\| DNA-binding response regulator [Bacillus cereus 03BB102], gi\|225785... gi\|52144036, gi\|... - gi\|52144036\|ref\|YP_082792.1\| response regulator [Bacillus cereus E33L], gi\|51977505\|gb\|AAU19055.1\| r... gi\|118416098, gi... - gi\|118476873\|ref\|YP_894024.1\| response regulator [Bacillus thuringiensis str. Al Hakam], gi\|11841609... gi\|218902506, gi... - gi\|218902506\|ref\|YP_002450340.1\| DNA-binding response regulator [Bacillus cereus AH820], gi\|21853851... gi\|254726203 - gi\|254726203\|ref\|ZP_05187985.1\| DNA-binding response regulator [Bacillus anthracis str. A1055] gi\|196022663, gi... - gi\|196046479\|ref\|ZP_03113704.1\| DNA-binding response regulator [Bacillus cereus 03BB108], gi\|1960226... gi\|196040638, gi... - gi\|196040638\|ref\|ZP_03107937.1\| DNA-binding response regulator [Bacillus cereus NVH0597-99], gi\|1960... gi\|195992031, gi... - gi\|196035354\|ref\|ZP_03102759.1\| DNA-binding response regulator [Bacillus cereus W], gi\|195992031\|gb\|...	180.0	[0..1]	[213..1]
gi\|196252895, gi... - gi\|196252895\|ref\|ZP_03151542.1\| two component transcriptional regulator, LuxR family [Clostridium th... gi\|67873312, gi\|... - gi\|67873312\|ref\|ZP_00503591.1\| regulatory protein, LuxR:Response regulator receiver [Clostridium the...	180.0	[0..1]	[208..1]
gi\|49477181, gi\|... - gi\|49477181\|ref\|YP_035526.1\| response regulator [Bacillus thuringiensis serovar konkukian str. 97-27...	180.0	[0..1]	[213..1]

Back

Predicted Domain #1

Region A:
Residues: [1-137]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNNMNVIIAD DHPIVLFGIR KSLEQIEWVN VVGEFEDSTA LINNLPKLDA HVLITDLSMP  60
   61 GDKYGDGITL IKYIKRHFPS LSIIVLTMNN NPAILSAVLD LDIEGIVLKQ GAPTDLPKAL 120
  121 AALQKGKKFT PESVSRL

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	5.88
Match:	2qsjA
Description:	No description for 2qsjA was found.

Predicted Domain #2

Region A:
Residues: [138-216]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LEKISAGGYG DKRLSPKESE VLRLFAEGFL VTEIAKKLNR SIKTISSQKK SAMMKLGVEN  60
   61 DIALLNYLSS VTLSPADKD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	5.0
Match:	1p4wA
Description:	Transcriptional regulator RcsB
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
two-component response regulator activity	5.29069184229407	bayes_pls_golite062009
transcription regulator activity	4.3783822692838	bayes_pls_golite062009
DNA binding	2.98242537415469	bayes_pls_golite062009
nucleic acid binding	2.90897931927895	bayes_pls_golite062009
transcription factor activity	2.57346479183384	bayes_pls_golite062009
signal transducer activity	2.28583654183469	bayes_pls_golite062009
molecular transducer activity	2.28583654183469	bayes_pls_golite062009
binding	1.861833300221	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: