YRC Public Data Repository - Protein Structure Prediction

Protein:	PTTBC_ECOLI, PTT...
Organism:	Escherichia coli
Length:	473 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PTTBC_ECOLI, PTT....

Description	E-value	Query Range	Subject Range
gi\|58336738, gi\|... - gi\|58336738\|ref\|YP_193323.1\| sucrose PTS II ABC [Lactobacillus acidophilus NCFM], gi\|58254055\|gb\|AAV... gi\|33149353 - gi\|33149353\|gb\|AAO38866.1\| sucrose PTS transporter [Lactobacillus acidophilus]	302.0	[0..5]	[471..2]
gi\|24380379, gi\|... - gi\|24380379\|ref\|NP_722334.1\| putative PTS system, trehalose-specific IIABC component [Streptococcus ... gi\|21217545 - gi\|21217545\|gb\|AAM43948.1\|AF510742_2 trehalose PTS enzyme II [Streptococcus mutans]	300.0	[0..5]	[472..3]
gi\|90961054, gi\|... - gi\|90961054\|ref\|YP_534970.1\| PTS system, sucrose-specific IIABC component [Lactobacillus salivarius ...	296.0	[0..5]	[473..2]
gi\|116095913, gi... - gi\|116630331\|ref\|YP_815592.1\| sucrose PTS, EIIBCA [Lactobacillus gasseri ATCC 33323], gi\|116095913\|g...	293.0	[0..5]	[472..2]
gi\|42519806, gi\|... - gi\|42519806\|ref\|NP_965736.1\| phosphoenolpyruvate-dependent sugar phosphotransferase system EIIABC, s...	293.0	[0..5]	[472..2]
gi\|28897484, gi\|... - gi\|28897484\|ref\|NP_797089.1\| trehalose(maltose)-specific PTS system components IIBC [Vibrio parahaem... gi\|28805696 - gi\|28805696\|dbj\|BAC58973.1\| PTS system, trehalose-specific IIBC component [Vibrio parahaemolyticus R...	293.0	[0..2]	[471..1]
gi\|116184008, gi... - gi\|75854561\|ref\|ZP_00762248.1\| COG1263: Phosphotransferase system IIC components, glucose/maltose/N-...	292.0	[0..2]	[471..1]
gi\|89105415, gi\|... - gi\|89105415\|ref\|ZP_01177935.1\| COG1263: Phosphotransferase system IIC components, glucose/maltose/N-... gi\|165919697, gi... - gi\|165928309\|ref\|ZP_02224141.1\| pts system, trehalose-specific IIBC component [Yersinia pestis biova... gi\|162353078, gi... - gi\|77633537\|ref\|ZP_00795663.1\| COG1263: Phosphotransferase system IIC components, glucose/maltose/N-... gi\|22124086, gi\|... - gi\|22124086\|ref\|NP_667509.1\| PTS system enzyme IIBC [Yersinia pestis KIM], gi\|21956835\|gb\|AAM83760.1... gi\|166211988, gi... - gi\|166211988\|ref\|ZP_02238023.1\| pts system, trehalose-specific IIBC component [Yersinia pestis biova... gi\|25287887 - pir\|\|AI0449 protein-Npi-phosphohistidine-sugar phosphotransferase (EC 2.7.1.69) IIBC component [impo... gi\|166011306, gi... - gi\|166011306\|ref\|ZP_02232204.1\| pts system, trehalose-specific IIBC component [Yersinia pestis biova... gi\|16123836, gi\|... - gi\|16123836\|ref\|NP_407149.1\| PTS system, trehalose-specific IIBC component [Yersinia pestis CO92], g... gi\|45443577, gi\|... - gi\|45443577\|ref\|NP_995116.1\| PTS system, trehalose-specific IIBC component [Yersinia pestis biovar M... gi\|167426731, gi... - gi\|167426731\|ref\|ZP_02318484.1\| pts system, trehalose-specific IIBC component [Yersinia pestis biova... gi\|153997368, gi... - gi\|153997368\|ref\|ZP_02022468.1\| PTS system, trehalose-specific IIBC component [Yersinia pestis CA88-...	287.0	[0..2]	[472..13]
gi\|77630536, gi\|... - gi\|77630536\|ref\|ZP_00793122.1\| COG1263: Phosphotransferase system IIC components, glucose/maltose/N-...	287.0	[0..2]	[472..13]

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Predicted Domain #1

Region A:
Residues: [1-85]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMSKINQTDI DRLIELVGGR GNIATVSHCI TRLRFVLNQP ANARPKEIEQ LPMVKGCFTN  60
   61 AGQFQVVIGT NVGDYYQALI ASTGQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	13.221849
Match:	1o2fB
Description:	Glucose permease domain IIB
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.61117010765727	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [86-299]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AQVDKEQVKK AARHNMKWHE QLISHFAVIF FPLLPALISG GLILGFRNVI GDLPMSNGQT  60
   61 LAQMYPSLQT IYDFLWLIGE AIFFYLPVGI CWSAVKKMGG TPILGIVLGV TLVSPQLMNA 120
  121 YLLGQQLPEV WDFGMFSIAK VGYQAQVIPA LLAGLALGVI ETRLKRIVPD YLYLVVVPVC 180
  181 SLILAVFLAH ALIGPFGRMI GDGVAFAVRH LMTG

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [300-473]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SFAPIGAALF GFLYAPLVIT GVHQTTLAID LQMIQSMGGT PVWPLIALSN IAQGSAVIGI  60
   61 IISSRKHNER EISVPAAISA WLGVTEPAMY GINLKYRFPM LCAMIGSGLA GLLCGLNGVM 120
  121 ANGIGVGGLP GILSIQPSYW QVFALAMAIA IIIPIVLTSF IYQRKYRLGT LDIV

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: