YRC Public Data Repository - Protein Structure Prediction

Protein:	PTPB1_ECOLI, PTP...
Organism:	Escherichia coli
Length:	158 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PTPB1_ECOLI, PTP....

Description	E-value	Query Range	Subject Range
gi\|226168, gi\|146724 - gi\|226168\|prf\|\|1413240A manX gene, gi\|146724\|gb\|AAA24110.1\| enzyme III-Man function protein (manX (p...	212.0	[0..6]	[158..156]
gi\|77633668, gi\|... - gi\|77633668\|ref\|ZP_00795789.1\| COG3444: Phosphotransferase system, mannose/fructose/N-acetylgalactos... gi\|149292704, gi... - gi\|149366291\|ref\|ZP_01888326.1\| PTS system, mannose-specific IIAB component [Yersinia pestis CA88-41... gi\|165938794, gi... - gi\|89104609\|ref\|ZP_01177148.1\| COG3444: Phosphotransferase system, mannose/fructose/N-acetylgalactos... gi\|145210348, gi... - gi\|145598652\|ref\|YP_001162728.1\| PTS system, mannose-specific IIAB component [Yersinia pestis Pestoi... gi\|108807126, gi... - gi\|108807126\|ref\|YP_651042.1\| PTS system, mannose-specific IIAB component [Yersinia pestis Antiqua],... gi\|229902909, gi... - gi\|229902909\|ref\|ZP_04518026.1\| mannose-specific PTS enzyme [Yersinia pestis Nepal516], gi\|229680356... gi\|25287843 - pir\|\|AE0214 protein-Npi-phosphohistidine-sugar phosphotransferase (EC 2.7.1.69) IIAB component [impo... gi\|51595970, gi\|... - gi\|51595970\|ref\|YP_070161.1\| PTS system, mannose-specific IIAB component [Yersinia pseudotuberculosi... gi\|22126432, gi\|... - gi\|22126432\|ref\|NP_669855.1\| PTS system, mannose-specific IIAB component [Yersinia pestis KIM], gi\|2... gi\|166210521, gi... - gi\|166210521\|ref\|ZP_02236556.1\| PTS system, mannose/fructose/sorbose family, IIB component [Yersinia... gi\|15979785, gi\|... - gi\|218928882\|ref\|YP_002346757.1\| PTS system, mannose-specific IIAB component [Yersinia pestis CO92],... gi\|166010853, gi... - gi\|166010853\|ref\|ZP_02231751.1\| PTS system, mannose/fructose/sorbose family, IIB component [Yersinia... gi\|166961879, gi... - gi\|167420184\|ref\|ZP_02311937.1\| PTS system, mannose/fructose/sorbose family, IIB component [Yersinia... gi\|167402186, gi... - gi\|167402186\|ref\|ZP_02307661.1\| PTS system, mannose/fructose/sorbose family, IIB component [Yersinia... gi\|170024689, gi... - gi\|170024689\|ref\|YP_001721194.1\| PTS system mannose/fructose/sorbose family IIB subunit [Yersinia ps... gi\|167425847, gi... - gi\|167425847\|ref\|ZP_02317600.1\| PTS system, mannose/fructose/sorbose family, IIB component [Yersinia... gi\|186895069, gi... - gi\|186895069\|ref\|YP_001872181.1\| PTS system mannose/fructose/sorbose family IIB subunit [Yersinia ps... gi\|229896196, gi... - gi\|229896196\|ref\|ZP_04511366.1\| mannose-specific PTS enzyme [Yersinia pestis Pestoides A], gi\|229701... gi\|229693469, gi... - gi\|229897132\|ref\|ZP_04512288.1\| mannose-specific PTS enzyme [Yersinia pestis biovar Orientalis str. ... Q66BY2\|Q66BY2_YERPS - PTS system, mannose-specific IIAB component - Yersinia pseudotuberculosis gi\|229897859, gi... - gi\|229897859\|ref\|ZP_04513010.1\| mannose-specific PTS enzyme [Yersinia pestis biovar Orientalis str. ... gi\|165920046, gi... - gi\|165927989\|ref\|ZP_02223821.1\| PTS system, mannose/fructose/sorbose family, IIB component [Yersinia...	212.0	[0..6]	[158..165]
gi\|153950698, gi... - gi\|77628834\|ref\|ZP_00791420.1\| COG3444: Phosphotransferase system, mannose/fructose/N-acetylgalactos...	211.0	[0..6]	[158..165]
gi\|45436311, gi\|... - gi\|45441450\|ref\|NP_992989.1\| PTS system, mannose-specific IIAB component [Yersinia pestis biovar Mic...	211.0	[0..6]	[158..143]
gi\|37201719, gi\|... - gi\|37677174\|ref\|NP_937570.1\| N-acetylgalactosamine-specific PTS system transporter subunit IIB [Vibr...	211.0	[0..1]	[157..34]
gi\|77972312, gi\|... - gi\|77972312\|ref\|ZP_00827882.1\| COG3444: Phosphotransferase system, mannose/fructose/N-acetylgalactos...	210.0	[0..6]	[158..165]
gi\|110614938, gi... - gi\|110805390\|ref\|YP_688910.1\| PTS enzyme IIAB [Shigella flexneri 5 str. 8401], gi\|110614938\|gb\|ABF03... EG10567 - fused mannose-specific PTS enzymes: IIA component /IIB component / Mannose permease, EIIAB component;... gi\|30041178, gi\|... - gi\|30062929\|ref\|NP_837100.1\| PTS enzyme IIAB [Shigella flexneri 2a str. 2457T], gi\|30041178\|gb\|AAP16... gi\|74311870, gi\|... - gi\|74311870\|ref\|YP_310289.1\| PTS enzyme IIAB, mannose-specific [Shigella sonnei Ss046], gi\|73855347\|... PTNAB_ECO57 - PTS system mannose-specific EIIAB component OS=Escherichia coli O157:H7 GN=manX PE=3 SV=2 PTNAB_ECOL6 - PTS system mannose-specific EIIAB component OS=Escherichia coli O6 GN=manX PE=3 SV=2 EG10567 - fused mannose-specific PTS enzymes: IIA component /IIB component / Mannose permease, EIIAB component;... gi\|75255556, gi\|... - gi\|75255556\|ref\|ZP_00727343.1\| COG3444: Phosphotransferase system, mannose/fructose/N-acetylgalactos... gi\|188492671, gi... - gi\|75513686\|ref\|ZP_00736062.1\| COG3444: Phosphotransferase system, mannose/fructose/N-acetylgalactos... gi\|168749349, gi... - gi\|188016260\|gb\|EDU54382.1\| PTS system, mannose-specific IIAB component [Escherichia coli O157:H7 st... gi\|82543739, gi\|... - gi\|82543739\|ref\|YP_407686.1\| PTS enzyme IIAB, mannose-specific [Shigella boydii Sb227], gi\|81245150\|... gi\|168758132, gi... - gi\|189355011\|gb\|EDU73430.1\| PTS system, mannose-specific IIAB component [Escherichia coli O157:H7 st... gi\|189365715, gi... - gi\|189365715\|gb\|EDU84131.1\| PTS system, mannose-specific IIAB component [Escherichia coli O157:H7 st... gi\|254592840, gi... - gi\|254793440\|ref\|YP_003078277.1\| mannose-specific PTS enzyme [Escherichia coli O157:H7 str. TW14359]... gi\|187731326, gi... - gi\|75177250\|ref\|ZP_00697339.1\| COG3444: Phosphotransferase system, mannose/fructose/N-acetylgalactos... gi\|254161876, gi... - gi\|254161876\|ref\|YP_003044984.1\| fused mannose-specific PTS enzymes: IIA component/IIB component [Es... gi\|157080889, gi... - gi\|75190848\|ref\|ZP_00704115.1\| COG3444: Phosphotransferase system, mannose/fructose/N-acetylgalactos... gi\|253773229, gi... - gi\|254288664\|ref\|YP_003054412.1\| fused mannose-specific PTS enzymes: IIA component/IIB component [Es... gi\|242377537, gi... - gi\|251785264\|ref\|YP_002999568.1\| hypothetical protein B21_01775 [Escherichia coli BL21], gi\|24237753... gi\|194439634, gi... - gi\|83585002\|ref\|ZP_00923657.1\| COG3444: Phosphotransferase system, mannose/fructose/N-acetylgalactos... gi\|238861210, gi... - gi\|238901031\|ref\|YP_002926827.1\| fused mannose-specific PTS enzymes: IIA component/IIB component [Es... gi\|75215178, gi\|... - gi\|75215178\|ref\|ZP_00713623.1\| COG3444: Phosphotransferase system, mannose/fructose/N-acetylgalactos... gi\|227837330, gi... - gi\|227885757\|ref\|ZP_04003562.1\| protein-N(pi)-phosphohistidine--sugar phosphotransferase [Escherichi... gi\|190901121, gi... - gi\|75227921\|ref\|ZP_00714621.1\| COG3444: Phosphotransferase system, mannose/fructose/N-acetylgalactos... gi\|75195884, gi\|... - gi\|75195884\|ref\|ZP_00705954.1\| COG3444: Phosphotransferase system, mannose/fructose/N-acetylgalactos... gi\|194430019, gi... - gi\|75208750\|ref\|ZP_00709042.1\| COG3444: Phosphotransferase system, mannose/fructose/N-acetylgalactos... gi\|208731111, gi... - gi\|208816768\|ref\|ZP_03257888.1\| PTS system, mannose-specific IIAB component [Escherichia coli O157:H... gi\|208741139, gi... - gi\|208821016\|ref\|ZP_03261336.1\| PTS system, mannose-specific IIAB component [Escherichia coli O157:H... gi\|209160968, gi... - gi\|209399568\|ref\|YP_002270896.1\| PTS system, mannose-specific IIAB component [Escherichia coli O157:... gi\|209912441, gi... - gi\|209919182\|ref\|YP_002293266.1\| PTS system mannose-specific IIAB components [Escherichia coli SE11]... gi\|217317966, gi... - gi\|217328619\|ref\|ZP_03444700.1\| PTS system, mannose-specific IIAB component [Escherichia coli O157:H... gi\|218361157, gi... - gi\|218554389\|ref\|YP_002387302.1\| fused mannose-specific PTS enzymes: IIA component ; IIB component [... gi\|218352111, gi... - gi\|218695379\|ref\|YP_002403046.1\| fused mannose-specific PTS enzymes: IIA component ; IIB component [... gi\|218432412, gi... - gi\|218705315\|ref\|YP_002412834.1\| fused mannose-specific PTS enzymes: IIA component ; IIB component [... gi\|168770795, gi... - gi\|189360337\|gb\|EDU78756.1\| PTS system, mannose-specific IIAB component [Escherichia coli O157:H7 st... gi\|168774864, gi... - gi\|187769489\|gb\|EDU33333.1\| PTS system, mannose-specific IIAB component [Escherichia coli O157:H7 st... gi\|1736455, gi\|8... - gi\|89108656\|ref\|AP_002436.1\| fused mannose-specific PTS enzyme IIAB components [Escherichia coli str... gi\|189000300, gi... - gi\|189000300\|gb\|EDU69286.1\| PTS system, mannose-specific IIAB component [Escherichia coli O157:H7 st... gi\|13361994, gi\|... - gi\|15831781\|ref\|NP_310554.1\| PTS system, mannose-specific IIAB component [Escherichia coli O157:H7 s... gi\|189371916, gi... - gi\|189371916\|gb\|EDU90332.1\| PTS system, mannose-specific IIAB component [Escherichia coli O157:H7 st... PTNAB_SHIFL - PTS system mannose-specific EIIAB component OS=Shigella flexneri GN=manX PE=3 SV=2 gi\|170081472, gi... - gi\|170081472\|ref\|YP_001730792.1\| fused mannose-specific PTS enzymes: IIA component; IIB component [E... PTNAB_ECOLI - PTS system mannose-specific EIIAB component (EIIAB-Man) [Includes: Mannose-specific phosphotransfera... gi\|170517999, gi... - gi\|170680281\|ref\|YP_001743429.1\| PTS system, mannose-specific IIAB component [Escherichia coli SMS-3... gi\|24112795, gi\|... - gi\|24112795\|ref\|NP_707305.1\| PTS enzyme IIAB [Shigella flexneri 2a str. 301], gi\|24051725\|gb\|AAN4301... gi\|195940311 - gi\|195940311\|ref\|ZP_03085693.1\| fused mannose-specific PTS enzymes: IIA component; IIB component [Es... PTNAB_ECOL6 - PTS system mannose-specific EIIAB component OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 /... gi\|208725186, gi... - gi\|208810670\|ref\|ZP_03252546.1\| PTS system, mannose-specific IIAB component [Escherichia coli O157:H...	210.0	[0..6]	[158..164]
gi\|218365448, gi... - gi\|218558679\|ref\|YP_002391592.1\| fused mannose-specific PTS enzymes: IIA component ; IIB component [... gi\|115513100, gi... - gi\|117623976\|ref\|YP_852889.1\| PTS system, mannose-specific IIAB component [Escherichia coli APEC O1]... gi\|237705767, gi... - gi\|237705767\|ref\|ZP_04536248.1\| PTS system [Escherichia sp. 3_2_53FAA], gi\|226900524\|gb\|EEH86783.1\| ... gi\|91072609, gi\|... - gi\|91211035\|ref\|YP_541021.1\| PTS system, mannose-specific IIAB component [Escherichia coli UTI89], g...	210.0	[0..6]	[158..164]
gi\|75241314, gi\|... - gi\|75241314\|ref\|ZP_00725165.1\| COG3444: Phosphotransferase system, mannose/fructose/N-acetylgalactos... gi\|110641934, gi... - gi\|110641934\|ref\|YP_669664.1\| PTS system, mannose-specific IIAB component [Escherichia coli 536], gi...	210.0	[0..6]	[158..164]
gi\|12515860, gi\|... - gi\|15802230\|ref\|NP_288253.1\| PTS system, mannose-specific IIAB component [Escherichia coli O157:H7 E... gi\|25287830 - gi\|25287830\|pir\|\|B85793 PTS enzyme IIAB, mannose-specific [imported] - Escherichia coli (strain O157...	210.0	[0..6]	[158..164]

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Predicted Domain #1

Region A:
Residues: [1-158]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSPNILLTR IDNRLVHGQV GVTWTSTIGA NLLVVVDDVV ANDDIQQKLM GITAETYGFG  60
   61 IRFFTIEKTI NVIGKAAPHQ KIFLICRTPQ TVRKLVEGGI DLKDVNVGNM HFSEGKKQIS 120
  121 SKVYVDDQDL TDLRFIKQRG VNVFIQDVPG DQKEQIPD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	51.30103
Match:	1nrzA
Description:	Sorbose permease subunit IIb , EIIb-sor
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
protein-N(PI)-phosphohistidine-sugar phosphotransferase activity	5.40782590240253	bayes_pls_golite062009
carbohydrate transmembrane transporter activity	4.44168757862841	bayes_pls_golite062009
transporter activity	1.71487898096445	bayes_pls_golite062009
transmembrane transporter activity	1.58926058776859	bayes_pls_golite062009
active transmembrane transporter activity	1.47735250312522	bayes_pls_golite062009
substrate-specific transporter activity	1.3255932049211	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	1.2097875448452	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.7338178608331	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.40258774521177	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: