YRC Public Data Repository - Protein Structure Prediction

Protein:	PABA_ECOLI
Organism:	Escherichia coli
Length:	187 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PABA_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|111612806, gi... - gi\|111612806\|ref\|ZP_01399890.1\| glutamine amidotransferase of anthranilate synthase [Verminephrobact...	225.0	[0..2]	[187..61]
gi\|83590188, gi\|... - gi\|83590188\|ref\|YP_430197.1\| anthranilate synthase, component II [Moorella thermoacetica ATCC 39073]...	224.0	[0..1]	[185..1]
gi\|218691642, gi... - gi\|218691642\|ref\|YP_002399854.1\| para-aminobenzoate synthase component II [Escherichia coli ED1a], g... gi\|91212837, gi\|... - gi\|91212837\|ref\|YP_542823.1\| para-aminobenzoate synthase component II [Escherichia coli UTI89], gi\|9... gi\|227839375, gi... - gi\|227883496\|ref\|ZP_04001301.1\| para-aminobenzoate synthase component II [Escherichia coli 83972], g... gi\|226902357, gi... - gi\|237703093\|ref\|ZP_04533574.1\| para-aminobenzoate synthase glutamine amidotransferase component II ... gi\|115514760, gi... - gi\|117625636\|ref\|YP_858959.1\| para-aminobenzoate synthase component II [Escherichia coli APEC O1], g... gi\|191171529, gi... - gi\|75241543\|ref\|ZP_00725388.1\| COG0512: Anthranilate/para-aminobenzoate synthases component II [Esch... gi\|110643600, gi... - gi\|110643600\|ref\|YP_671330.1\| para-aminobenzoate synthase component II [Escherichia coli 536], gi\|11... gi\|218367192, gi... - gi\|218560423\|ref\|YP_002393336.1\| para-aminobenzoate synthase component II [Escherichia coli S88], gi... gi\|26249959, gi\|... - gi\|26249959\|ref\|NP_755999.1\| para-aminobenzoate synthase component II [Escherichia coli CFT073], gi\|...	224.0	[0..1]	[187..1]
gi\|88941753, gi\|... - gi\|88941753\|ref\|ZP_01147155.1\| anthranilate phosphoribosyltransferase [Acidiphilium cryptum JF-5], g...	224.0	[0..1]	[185..1]
gi\|82778641, gi\|... - gi\|82778641\|ref\|YP_404990.1\| para-aminobenzoate synthase component II [Shigella dysenteriae Sd197], ...	224.0	[0..1]	[187..1]
gi\|56477813, gi\|... - gi\|56477813\|ref\|YP_159402.1\| anthranilate synthase (component II) [Aromatoleum aromaticum EbN1], gi\|...	224.0	[0..1]	[187..1]
gi\|217324460, gi... - gi\|217324460\|ref\|ZP_03440544.1\| aminodeoxychorismate synthase, component II [Escherichia coli O157:H... gi\|208812957, gi... - gi\|208812957\|ref\|ZP_03254286.1\| aminodeoxychorismate synthase, component II [Escherichia coli O157:H... gi\|208729357, gi... - gi\|208809556\|ref\|ZP_03251893.1\| aminodeoxychorismate synthase, component II [Escherichia coli O157:H... gi\|209157464, gi... - gi\|209396064\|ref\|YP_002272802.1\| aminodeoxychorismate synthase, component II [Escherichia coli O157:... gi\|208821415, gi... - gi\|208821415\|ref\|ZP_03261735.1\| aminodeoxychorismate synthase, component II [Escherichia coli O157:H... gi\|13363684, gi\|... - gi\|15833465\|ref\|NP_312238.1\| para-aminobenzoate synthase component II [Escherichia coli O157:H7], gi... gi\|168785170, gi... - gi\|189374309\|gb\|EDU92725.1\| aminodeoxychorismate synthase, component II [Escherichia coli O157:H7 st... gi\|209756822, gi... - pir\|\|H86000 p-aminobenzoate synthetase, component II [imported] - Escherichia coli (strain O157:H7, ... gi\|189002404, gi... - gi\|189002404\|gb\|EDU71390.1\| aminodeoxychorismate synthase, component II [Escherichia coli O157:H7 st... gi\|195934858 - gi\|195934858\|ref\|ZP_03080240.1\| para-aminobenzoate synthase component II [Escherichia coli O157:H7 s... gi\|15803874, gi\|... - gi\|15803874\|ref\|NP_289908.1\| para-aminobenzoate synthase component II [Escherichia coli O157:H7 EDL9... gi\|189380149, gi... - gi\|189380149\|gb\|EDU98565.1\| aminodeoxychorismate synthase, component II [Escherichia coli O157:H7 st... gi\|189369905, gi... - gi\|189369905\|gb\|EDU88321.1\| aminodeoxychorismate synthase, component II [Escherichia coli O157:H7 st... gi\|189359113, gi... - gi\|189359113\|gb\|EDU77532.1\| aminodeoxychorismate synthase, component II [Escherichia coli O157:H7 st... gi\|168772742, gi... - gi\|187771712\|gb\|EDU35556.1\| aminodeoxychorismate synthase, component II [Escherichia coli O157:H7 st... gi\|168765713, gi... - gi\|189364793\|gb\|EDU83212.1\| aminodeoxychorismate synthase, component II [Escherichia coli O157:H7 st... gi\|188014202, gi... - gi\|188014202\|gb\|EDU52324.1\| aminodeoxychorismate synthase, component II [Escherichia coli O157:H7 st... gi\|254795284, gi... - gi\|254795284\|ref\|YP_003080121.1\| aminodeoxychorismate synthase, subunit II [Escherichia coli O157:H7... gi\|13363684, gi\|... - gi\|15833465\|ref\|NP_312238.1\| para-aminobenzoate synthase component II [Escherichia coli O157:H7 str....	223.0	[0..1]	[187..1]
gi\|72120121, gi\|... - gi\|73542708\|ref\|YP_297228.1\| anthranilate synthase component II [Ralstonia eutropha JMP134], gi\|7212...	222.0	[0..1]	[186..17]
gi\|197938528, gi... - gi\|198244012\|ref\|YP_002217430.1\| aminodeoxychorismate synthase, component II [Salmonella enterica su... gi\|197265499, gi... - gi\|197265499\|ref\|ZP_03165573.1\| aminodeoxychorismate synthase, component II [Salmonella enterica sub... gi\|197247694, gi... - gi\|197247694\|ref\|YP_002148388.1\| aminodeoxychorismate synthase, component II [Salmonella enterica su... PABA_SALTY - Aminodeoxychorismate synthase component 2 OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 70... gi\|167994569, gi... - gi\|205327603\|gb\|EDZ14367.1\| aminodeoxychorismate synthase, component II [Salmonella enterica subsp. ... PABA_SALTY - Para-aminobenzoate synthase glutamine amidotransferase component II OS=Salmonella typhimurium GN=pab... gi\|207858710, gi... - gi\|207858710\|ref\|YP_002245361.1\| para-aminobenzoate synthase component II [Salmonella enterica subsp... lcl\|NC_016856.1_... - [gene=pabA] [protein=para-aminobenzoate synthase component II] [protein_id=YP_005239662.1] [location... PABA_SALTY - Para-aminobenzoate synthase glutamine amidotransferase component II OS=Salmonella typhimurium GN=pab...	222.0	[0..1]	[187..1]
gi\|110336432, gi... - gi\|121592801\|ref\|YP_984697.1\| anthranilate synthase component II [Acidovorax sp. JS42], gi\|120604881...	222.0	[0..2]	[187..4]

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Predicted Domain #1

Region A:
Residues: [1-187]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MILLIDNYDS FTWNLYQYFC ELGADVLVKR NDALTLADID ALKPQKIVIS PGPCTPDEAG  60
   61 ISLDVIRHYA GRLPILGVCL GHQAMAQAFG GKVVRAAKVM HGKTSPITHN GEGVFRGLAN 120
  121 PLTVTRYHSL VVEPDSLPAC FDVTAWSETR EIMGIRHRQW DLEGVQFHPE SILSEQGHQL 180
  181 LANFLHR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	41.69897
Match:	1qdlB
Description:	Anthranilate synthase GAT subunit, TrpG
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
4-amino-4-deoxychorismate synthase activity	4.48164623771604	bayes_pls_golite062009
anthranilate synthase activity	2.51214170411838	bayes_pls_golite062009
ligase activity	1.77692713123297	bayes_pls_golite062009
oxo-acid-lyase activity	1.35896725827905	bayes_pls_golite062009
catalytic activity	1.30391542469987	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	0.628648036096965	bayes_pls_golite062009
imidazoleglycerol-phosphate synthase activity	0.270391651600004	bayes_pls_golite062009
carbon-carbon lyase activity	0.0769356405014503	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: