YRC Public Data Repository - Protein Structure Prediction

Protein:	NARI_ECOLI
Organism:	Escherichia coli
Length:	225 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NARI_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|62127781, gi\|... - gi\|62180148\|ref\|YP_216565.1\| nitrate reductase 2, gamma subunit [Salmonella enterica subsp. enterica...	229.0	[0..1]	[224..231]
NARX_MYCTU - Nitrate reductase-like protein NarX OS=Mycobacterium tuberculosis GN=narX PE=1 SV=2 NARX_MYCTO - Nitrate reductase-like protein NarX OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) GN=nar... NARX_MYCTU - Nitrate reductase-like protein NarX OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) GN=nar... gi\|148661535, gi... - gi\|167968650\|ref\|ZP_02550927.1\| nitrate reductase narX [Mycobacterium tuberculosis H37Ra], gi\|148661... gi\|215411386 - gi\|215411386\|ref\|ZP_03420194.1\| nitrate reductase narX [Mycobacterium tuberculosis 94_M4241A] gi\|253799222, gi... - gi\|253799222\|ref\|YP_003032223.1\| nitrate reductase narX [Mycobacterium tuberculosis KZN 1435], gi\|25... gi\|215403956 - gi\|215403956\|ref\|ZP_03416137.1\| nitrate reductase narX [Mycobacterium tuberculosis 02_1987] gi\|254550749 - gi\|254550749\|ref\|ZP_05141196.1\| nitrate reductase narX [Mycobacterium tuberculosis '98-R604 INH-RIF-... gi\|254815534 - gi\|254815534\|ref\|ZP_05220535.1\| nitrate reductase narX [Mycobacterium tuberculosis KZN 4207] gi\|76784529, gi\|... - gi\|76784529\|ref\|ZP_00771713.1\| COG5013: Nitrate reductase alpha subunit [Mycobacterium tuberculosis ... gi\|218753446 - gi\|218753446\|ref\|ZP_03532242.1\| nitrate reductase narX [Mycobacterium tuberculosis GM 1503] gi\|255096514 - gi\|255096514\|ref\|ZP_05325992.1\| nitrate reductase narX [Mycobacterium tuberculosis KZN 605]	209.0	[0..2]	[224..415]
gi\|121493291, gi... - gi\|121637644\|ref\|YP_977867.1\| putative nitrate reductase NarX [Mycobacterium bovis BCG str. Pasteur ... gi\|224990119, gi... - gi\|224990119\|ref\|YP_002644806.1\| putative nitrate reductase [Mycobacterium bovis BCG str. Tokyo 172]... gi\|31792924, gi\|... - gi\|31792924\|ref\|NP_855417.1\| nitrate reductase NarX [Mycobacterium bovis AF2122/97], gi\|31618515\|emb... gi\|6651231 - gi\|6651231\|gb\|AAF22229.1\|AF149772_1 fused nitrate reductase [Mycobacterium bovis BCG]	208.0	[0..2]	[224..415]
gi\|92113459, gi\|... - gi\|92113459\|ref\|YP_573387.1\| respiratory nitrate reductase gamma subunit [Chromohalobacter salexigen...	199.0	[0..1]	[224..1]
gi\|77979845 - gi\|77979845\|ref\|ZP_00835261.1\| COG2181: Nitrate reductase gamma subunit [Yersinia intermedia ATCC 29...	197.0	[0..1]	[225..1]
gi\|145295325, gi... - gi\|145295325\|ref\|YP_001138146.1\| hypothetical protein cgR_1265 [Corynebacterium glutamicum R], gi\|14... gi\|62390074, gi\|... - gi\|62390074\|ref\|YP_225476.1\| respiratory nitrate reductase 2 gamma chain [Corynebacterium glutamicum...	194.0	[0..1]	[225..1]
gi\|110343051, gi... - gi\|110641459\|ref\|YP_669189.1\| respiratory nitrate reductase 1 gamma chain [Escherichia coli 536], gi...	192.0	[0..1]	[225..1]
gi\|219668884, gi... - gi\|68206532\|ref\|ZP_00558718.1\| 4Fe-4S ferredoxin, iron-sulfur binding domain:Protein of unknown func... gi\|89333907, gi\|... - gi\|89894459\|ref\|YP_517946.1\| hypothetical protein DSY1713 [Desulfitobacterium hafniense Y51], gi\|893...	191.0	[0..3]	[216..7]
gi\|24051533, gi\|... - gi\|24112626\|ref\|NP_707136.1\| nitrate reductase 1, cytochrome b(NR), gamma subunit [Shigella flexneri...	191.0	[0..1]	[225..1]
gi\|82544318, gi\|... - gi\|82544318\|ref\|YP_408265.1\| nitrate reductase 1 cytochrome b(NR), gamma subunit [Shigella boydii Sb...	191.0	[0..1]	[225..1]

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Predicted Domain #1

Region A:
Residues: [1-225]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQFLNMFFFD IYPYIAGAVF LIGSWLRYDY GQYTWRAASS QMLDRKGMNL ASNLFHIGIL  60
   61 GIFVGHFFGM LTPHWMYEAW LPIEVKQKMA MFAGGASGVL CLIGGVLLLK RRLFSPRVRA 120
  121 TTTGADILIL SLLVIQCALG LLTIPFSAQH MDGSEMMKLV GWAQSVVTFH GGASQHLDGV 180
  181 AFIFRLHLVL GMTLFLLFPF SRLIHIWSVP VEYLTRKYQL VRARH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	48.522879
Match:	1q16C
Description:	Crystal structure of Nitrate Reductase A, NarGHI, from Escherichia coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nitrate reductase activity	8.42060418947243	bayes_pls_golite062009
oxidoreductase activity, acting on other nitrogenous compounds as donors	7.2464995846242	bayes_pls_golite062009
binding	1.18350763063367	bayes_pls_golite062009
electron carrier activity	1.14948153252384	bayes_pls_golite062009
catalytic activity	0.434711796157625	bayes_pls_golite062009
oxidoreductase activity	0.34569235854639	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: