YRC Public Data Repository - Protein Structure Prediction

Protein:	MIPA_ECOLI
Organism:	Escherichia coli
Length:	248 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MIPA_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|213580824 - gi\|213580824\|ref\|ZP_03362650.1\| MltA-interacting protein [Salmonella enterica subsp. enterica serova... gi\|213427975 - gi\|213427975\|ref\|ZP_03360725.1\| MltA-interacting protein [Salmonella enterica subsp. enterica serova... gi\|213418192 - gi\|213418192\|ref\|ZP_03351258.1\| MltA-interacting protein [Salmonella enterica subsp. enterica serova... gi\|207857213, gi... - gi\|207857213\|ref\|YP_002243864.1\| putative outer membrane protein [Salmonella enterica subsp. enteric... gi\|214003040 - gi\|214003040\|ref\|ZP_03413775.1\| MltA-interacting protein [Salmonella enterica subsp. enterica serova... gi\|213974793 - gi\|213974793\|ref\|ZP_03402052.1\| MltA-interacting protein [Salmonella enterica subsp. enterica serova... gi\|213646213 - gi\|213646213\|ref\|ZP_03376266.1\| MltA-interacting protein [Salmonella enterica subsp. enterica serova... gi\|213613244 - gi\|213613244\|ref\|ZP_03371070.1\| MltA-interacting protein [Salmonella enterica subsp. enterica serova... gi\|29141633, gi\|... - gi\|29141633\|ref\|NP_804975.1\| putative outer membrane protein [Salmonella enterica subsp. enterica se... gi\|205341582, gi... - gi\|205341582\|gb\|EDZ28346.1\| MltA-interacting protein [Salmonella enterica subsp. enterica serovar We... gi\|16760608 - gi\|16760608\|ref\|NP_456225.1\| putative outer membrane protein [Salmonella enterica subsp. enterica se... gi\|205347304, gi... - gi\|205347304\|gb\|EDZ33935.1\| MltA-interacting protein [Salmonella enterica subsp. enterica serovar Ha... gi\|16502904, gi\|... - gi\|25325846\|pir\|\|AC0712 probable outer membrane protein STY1830 [imported] - Salmonella enterica sub... gi\|205336793, gi... - gi\|205336793\|gb\|EDZ23557.1\| MltA-interacting protein [Salmonella enterica subsp. enterica serovar He... gi\|16419803, gi\|... - gi\|16764637\|ref\|NP_460252.1\| MltA-interacting protein A [Salmonella typhimurium LT2], gi\|16419803\|gb... gi\|205329758, gi... - gi\|205329758\|gb\|EDZ16522.1\| MltA-interacting protein [Salmonella enterica subsp. enterica serovar 4,... gi\|197936956, gi... - gi\|198242440\|ref\|YP_002215849.1\| MltA-interacting protein [Salmonella enterica subsp. enterica serov... gi\|197265083, gi... - gi\|197265083\|ref\|ZP_03165157.1\| MltA-interacting protein [Salmonella enterica subsp. enterica serova... gi\|197251413, gi... - gi\|197251413\|ref\|YP_002146753.1\| MltA-interacting protein [Salmonella enterica subsp. enterica serov... gi\|194406172, gi... - gi\|194447868\|ref\|YP_002045292.1\| MltA-interacting protein [Salmonella enterica subsp. enterica serov... lcl\|NC_016856.1_... - [gene=mipA] [protein=MltA-interacting protein A] [protein_id=YP_005237135.1] [location=1374166..1374... gi\|161363678, gi... - gi\|161614314\|ref\|YP_001588279.1\| hypothetical protein SPAB_02060 [Salmonella enterica subsp. enteric... gi\|238910897 - gi\|238910897\|ref\|ZP_04654734.1\| putative outer membrane protein [Salmonella enterica subsp. enterica...	232.0	[0..1]	[248..1]
gi\|197094127, gi... - gi\|197362650\|ref\|YP_002142287.1\| putative outer membrane protein [Salmonella enterica subsp. enteric... gi\|56127985, gi\|... - gi\|56413728\|ref\|YP_150803.1\| putative outer membrane protein [Salmonella enterica subsp. enterica se...	232.0	[0..1]	[248..1]
gi\|62127501, gi\|... - gi\|62179868\|ref\|YP_216285.1\| scaffolding protein for murein-synthesizing holoenzyme [Salmonella ente...	230.0	[0..1]	[248..1]
gi\|194433465, gi... - gi\|83569610\|ref\|ZP_00921061.1\| COG3713: Outer membrane protein V [Shigella dysenteriae 1012], gi\|194...	228.0	[0..1]	[248..1]
gi\|26248041, gi\|... - gi\|26248041\|ref\|NP_754081.1\| MltA-interacting protein precursor [Escherichia coli CFT073], gi\|261084...	228.0	[0..1]	[248..1]
gi\|75241343, gi\|... - gi\|75241343\|ref\|ZP_00725194.1\| COG3713: Outer membrane protein V [Escherichia coli F11], gi\|19117165... gi\|110641904, gi... - gi\|110641904\|ref\|YP_669634.1\| MltA-interacting protein precursor [Escherichia coli 536], gi\|11034349...	227.0	[0..1]	[248..1]
gi\|254592804, gi... - gi\|254793404\|ref\|YP_003078241.1\| scaffolding protein for murein synthesizing machinery [Escherichia ... gi\|15831745, gi\|... - gi\|15831745\|ref\|NP_310518.1\| putative scaffolding protein in the formation of a murein-synthesizing ... gi\|217328994, gi... - gi\|217328994\|ref\|ZP_03445075.1\| MltA-interacting protein MipA [Escherichia coli O157:H7 str. TW14588... gi\|209162024, gi... - gi\|209400624\|ref\|YP_002270857.1\| MltA-interacting protein MipA [Escherichia coli O157:H7 str. EC4115... gi\|25325844, gi\|... - pir\|\|G85788 hypothetical protein yeaF [imported] - Escherichia coli (strain O157:H7, substrain EDL9... gi\|12515816, gi\|... - gi\|15802196\|ref\|NP_288218.1\| hypothetical protein Z2822 [Escherichia coli O157:H7 EDL933], gi\|125158... gi\|15831745, gi\|... - gi\|15831745\|ref\|NP_310518.1\| putative scaffolding protein in the formation of a murein-synthesizing ... gi\|189376756, gi... - gi\|189376756\|gb\|EDU95172.1\| MltA-interacting protein MipA [Escherichia coli O157:H7 str. EC508], gi\|... gi\|189372026, gi... - gi\|189372026\|gb\|EDU90442.1\| MltA-interacting protein MipA [Escherichia coli O157:H7 str. EC869], gi\|... gi\|189000331, gi... - gi\|189000331\|gb\|EDU69317.1\| MltA-interacting protein MipA [Escherichia coli O157:H7 str. EC4076], gi... gi\|187769383, gi... - gi\|187769383\|gb\|EDU33227.1\| MltA-interacting protein MipA [Escherichia coli O157:H7 str. EC4196], gi... gi\|208818624, gi... - gi\|208818624\|ref\|ZP_03258944.1\| MltA-interacting protein MipA [Escherichia coli O157:H7 str. EC4042]... gi\|208731364, gi... - gi\|208817021\|ref\|ZP_03258141.1\| MltA-interacting protein MipA [Escherichia coli O157:H7 str. EC4045]... gi\|208810214, gi... - gi\|208810214\|ref\|ZP_03252090.1\| MltA-interacting protein MipA [Escherichia coli O157:H7 str. EC4206]... gi\|195937470 - gi\|195937470\|ref\|ZP_03082852.1\| putative scaffolding protein in the formation of a murein-synthesizi... gi\|189360395, gi... - gi\|189360395\|gb\|EDU78814.1\| MltA-interacting protein MipA [Escherichia coli O157:H7 str. EC4486], gi... gi\|189365704, gi... - gi\|189365704\|gb\|EDU84120.1\| MltA-interacting protein MipA [Escherichia coli O157:H7 str. EC4501], gi... gi\|168758087, gi... - gi\|189355032\|gb\|EDU73451.1\| MltA-interacting protein MipA [Escherichia coli O157:H7 str. EC4401], gi... gi\|188016313, gi... - gi\|188016313\|gb\|EDU54435.1\| MltA-interacting protein MipA [Escherichia coli O157:H7 str. EC4113], gi...	227.0	[0..1]	[248..1]
gi\|153949500, gi... - gi\|77629164\|ref\|ZP_00791750.1\| COG3713: Outer membrane protein V [Yersinia pseudotuberculosis IP 317... gi\|165927683, gi... - gi\|165927683\|ref\|ZP_02223515.1\| MltA-interacting protein [Yersinia pestis biovar Orientalis str. F19... gi\|165991956, gi... - gi\|166009401\|ref\|ZP_02230299.1\| MltA-interacting protein [Yersinia pestis biovar Antiqua str. E19790... gi\|229702302, gi... - gi\|229894829\|ref\|ZP_04510009.1\| scaffolding protein for murein synthesizing machinery [Yersinia pest... gi\|166208324, gi... - gi\|166211144\|ref\|ZP_02237179.1\| MltA-interacting protein [Yersinia pestis biovar Antiqua str. B42003... gi\|229693910, gi... - gi\|229897573\|ref\|ZP_04512729.1\| scaffolding protein for murein synthesizing machinery [Yersinia pest... gi\|167401473, gi... - gi\|167401473\|ref\|ZP_02306970.1\| MltA-interacting protein [Yersinia pestis biovar Antiqua str. UG05-0... gi\|229898218, gi... - gi\|229898218\|ref\|ZP_04513366.1\| scaffolding protein for murein synthesizing machinery [Yersinia pest... gi\|166961855, gi... - gi\|167420160\|ref\|ZP_02311913.1\| MltA-interacting protein [Yersinia pestis biovar Orientalis str. MG0... gi\|89101821, gi\|... - gi\|89101821\|ref\|ZP_01174513.1\| COG3713: Outer membrane protein V [Yersinia pestis biovar Orientalis ... gi\|167054429, gi... - gi\|167426553\|ref\|ZP_02318306.1\| MltA-interacting protein [Yersinia pestis biovar Mediaevalis str. K1... gi\|108807508, gi... - gi\|108807508\|ref\|YP_651424.1\| hypothetical protein YPA_1512 [Yersinia pestis Antiqua], gi\|108779421\|... gi\|170024332, gi... - gi\|170024332\|ref\|YP_001720837.1\| MltA-interacting MipA family protein [Yersinia pseudotuberculosis Y... gi\|229902079, gi... - gi\|229902079\|ref\|ZP_04517200.1\| scaffolding protein for murein synthesizing machinery [Yersinia pest... gi\|186895452, gi... - gi\|186895452\|ref\|YP_001872564.1\| MltA-interacting MipA family protein [Yersinia pseudotuberculosis P... Q66AP9\|Q66AP9_YERPS - Putative exported protein precursor - Yersinia pseudotuberculosis gi\|25325845 - pir\|\|AG0262 probable exported protein YPO2155 [imported] - Yersinia pestis (strain CO92) gi\|45441756, gi\|... - gi\|45441756\|ref\|NP_993295.1\| hypothetical protein YP_1955 [Yersinia pestis biovar Microtus str. 9100... gi\|22126055, gi\|... - gi\|22126055\|ref\|NP_669478.1\| hypothetical protein y2167 [Yersinia pestis KIM], gi\|21959008\|gb\|AAM857... gi\|16122387, gi\|... - gi\|218929255\|ref\|YP_002347130.1\| hypothetical protein YPO2155 [Yersinia pestis CO92], gi\|16122387\|re... gi\|51596407, gi\|... - gi\|51596407\|ref\|YP_070598.1\| hypothetical protein YPTB2081 [Yersinia pseudotuberculosis IP 32953], g... gi\|77634450 - gi\|77634450\|ref\|ZP_00796550.1\| COG3713: Outer membrane protein V [Yersinia pestis Angola] gi\|149292335, gi... - gi\|149365922\|ref\|ZP_01887957.1\| putative exported protein [Yersinia pestis CA88-4125], gi\|149292335\|... gi\|145209972, gi... - gi\|145598276\|ref\|YP_001162352.1\| hypothetical protein YPDSF_0979 [Yersinia pestis Pestoides F], gi\|1...	226.0	[0..4]	[248..12]
gi\|77973572 - gi\|77973572\|ref\|ZP_00829119.1\| COG3713: Outer membrane protein V [Yersinia frederiksenii ATCC 33641]	211.0	[0..23]	[248..6]
gi\|77977684 - gi\|77977684\|ref\|ZP_00833126.1\| COG3713: Outer membrane protein V [Yersinia intermedia ATCC 29909]	210.0	[0..23]	[248..6]

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Predicted Domain #1

Region A:
Residues: [1-248]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTKLKLLALG VLIATSAGVA HAEGKFSLGA GVGVVEHPYK DYDTDVYPVP VINYEGDNFW  60
   61 FRGLGGGYYL WNDATDKLSI TAYWSPLYFK AKDSGDHQMR HLDDRKSTMM AGLSYAHFTQ 120
  121 YGYLRTTLAG DTLDNSNGIV WDMAWLYRYT NGGLTVTPGI GVQWNSENQN EYYYGVSRKE 180
  181 SARSGLRGYN PNDSWSPYLE LSASYNFLGD WSVYGTARYT RLSDEVTDSP MVDKSWTGLI 240
  241 STGITYKF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	20.09691
Match:	1bxwA
Description:	Outer membrane protein A (OMPA) transmembrane domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
porin activity	4.1108495362755	bayes_pls_golite062009
wide pore channel activity	3.18531781599537	bayes_pls_golite062009
binding	0.660276808926851	bayes_pls_golite062009
protein binding	0.27305872597094	bayes_pls_golite062009
receptor activity	0.091429531336731	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: