YRC Public Data Repository - Protein Structure Prediction

Protein:	MANC_ECOLI
Organism:	Escherichia coli
Length:	478 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MANC_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|11992720 - gi\|11992720\|gb\|AAG41703.1\| GDP-mannose pyrophosphorylase [Salmonella enterica subsp. indica]	445.0	[0..6]	[478..1]
gi\|11992956 - gi\|11992956\|gb\|AAG41701.1\| GDP-mannose pyrophosphorylase [Salmonella enterica subsp. enterica]	445.0	[0..1]	[478..1]
gi\|196111565, gi... - gi\|88795878\|ref\|ZP_01111567.1\| mannose-1-phosphate guanylyltransferase [Alteromonas macleodii 'Deep ...	445.0	[0..6]	[478..1]
gi\|46019524 - gi\|46019524\|emb\|CAE53852.1\| mannose-1-phosphate guanylytransferase, ManC protein [Yersinia enterocol...	444.0	[0..4]	[477..1]
gi\|62128297, gi\|... - gi\|62180664\|ref\|YP_217081.1\| phosphomannomutase in colanic acid gene cluster [Salmonella enterica su... gi\|199605419, gi... - gi\|200388321\|ref\|ZP_03214933.1\| mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomeras...	443.0	[0..6]	[477..2]
gi\|78037690, gi\|... - gi\|78049260\|ref\|YP_365435.1\| phosphomannose isomerase / gdpmannose dehydrogenase [Xanthomonas campes...	441.0	[0..3]	[477..1]
gi\|83588042, gi\|... - gi\|83588042\|ref\|ZP_00926667.1\| COG0836: Mannose-1-phosphate guanylyltransferase [Escherichia coli 10...	441.0	[0..1]	[478..1]
gi\|77975891, gi\|... - gi\|77975891\|ref\|ZP_00831425.1\| COG0836: Mannose-1-phosphate guanylyltransferase [Yersinia frederikse...	440.0	[0..6]	[477..2]
gi\|15832108, gi\|... - gi\|15832108\|ref\|NP_310881.1\| mannose-1-phosphate guanyltransferase [Escherichia coli O157:H7 str. Sa... gi\|208740616, gi... - gi\|208820493\|ref\|ZP_03260813.1\| mannose-1-phosphate guanylyltransferase [Escherichia coli O157:H7 st... gi\|209157718, gi... - gi\|209396318\|ref\|YP_002271292.1\| mannose-1-phosphate guanylyltransferase [Escherichia coli O157:H7 s... gi\|254793833, gi... - gi\|254793833\|ref\|YP_003078670.1\| mannose-1-phosphate guanyltransferase [Escherichia coli O157:H7 str... gi\|217317305, gi... - gi\|217329537\|ref\|ZP_03445616.1\| mannose-1-phosphate guanylyltransferase [Escherichia coli O157:H7 st... gi\|168799068, gi... - gi\|189378453\|gb\|EDU96869.1\| mannose-1-phosphate guanylyltransferase [Escherichia coli O157:H7 str. E... gi\|195938242 - gi\|195938242\|ref\|ZP_03083624.1\| mannose-1-phosphate guanyltransferase [Escherichia coli O157:H7 str.... gi\|208725673, gi... - gi\|208805872\|ref\|ZP_03248209.1\| mannose-1-phosphate guanylyltransferase [Escherichia coli O157:H7 st... gi\|208817213, gi... - gi\|208817213\|ref\|ZP_03258305.1\| mannose-1-phosphate guanylyltransferase [Escherichia coli O157:H7 st... gi\|189361253, gi... - gi\|189361253\|gb\|EDU79672.1\| mannose-1-phosphate guanylyltransferase [Escherichia coli O157:H7 str. E... gi\|168775501, gi... - gi\|187768990\|gb\|EDU32834.1\| mannose-1-phosphate guanylyltransferase [Escherichia coli O157:H7 str. E... gi\|168782334, gi... - gi\|189000196\|gb\|EDU69182.1\| mannose-1-phosphate guanylyltransferase [Escherichia coli O157:H7 str. E... gi\|189371563, gi... - gi\|189371563\|gb\|EDU89979.1\| mannose-1-phosphate guanylyltransferase [Escherichia coli O157:H7 str. E... gi\|168750441, gi... - gi\|188015381\|gb\|EDU53503.1\| mannose-1-phosphate guanylyltransferase [Escherichia coli O157:H7 str. E... MANC1_ECO57 - Mannose-1-phosphate guanylyltransferase 1 OS=Escherichia coli O157:H7 GN=manC1 PE=1 SV=1 gi\|189355140, gi... - gi\|189355140\|gb\|EDU73559.1\| mannose-1-phosphate guanylyltransferase [Escherichia coli O157:H7 str. E... gi\|209748106, gi... - pir\|\|A85831 mannose-1-phosphate guanyltransferase [imported] - Escherichia coli (strain O157:H7, sub... gi\|168761793, gi... - gi\|189367840\|gb\|EDU86256.1\| mannose-1-phosphate guanylyltransferase [Escherichia coli O157:H7 str. E... gi\|12516243, gi\|... - gi\|15802529\|ref\|NP_288555.1\| mannose-1-phosphate guanyltransferase [Escherichia coli O157:H7 EDL933]...	440.0	[0..1]	[478..1]
gi\|91072910, gi\|... - gi\|91211336\|ref\|YP_541322.1\| mannose-1-phosphate guanylyltransferase [Escherichia coli UTI89], gi\|91... gi\|110642259, gi... - gi\|110642259\|ref\|YP_669989.1\| mannose-1-phosphate guanylyltransferase [Escherichia coli 536], gi\|110... gi\|75242871, gi\|... - gi\|75242871\|ref\|ZP_00726577.1\| COG0836: Mannose-1-phosphate guanylyltransferase [Escherichia coli F1... gi\|26248423, gi\|... - gi\|26248423\|ref\|NP_754463.1\| mannose-1-phosphate guanylyltransferase [Escherichia coli CFT073], gi\|2... gi\|187430515, gi... - gi\|75177169\|ref\|ZP_00697267.1\| COG0836: Mannose-1-phosphate guanylyltransferase [Shigella boydii BS5...	440.0	[0..1]	[478..1]

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Predicted Domain #1

Region A:
Residues: [1-365]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQSKLYPVV MAGGSGSRLW PLSRVLYPKQ FLCLKGDLTM LQTTICRLNG VECESPVVIC  60
   61 NEQHRFIVAE QLRQLNKLTE NIILEPAGRN TAPAIALAAL AAKRHSPESD PLMLVLAADH 120
  121 VIADEDAFRA AVRNAMPYAE AGKLVTFGIV PDLPETGYGY IRRGEVSAGE QDMVAFEVAQ 180
  181 FVEKPNLETA QAYVASGEYY WNSGMFLFRA GRYLEELKKY RPDILDACEK AMSAVDPDLN 240
  241 FIRVDEEAFL ACPEESVDYA VMERTADAVV VPMDAGWSDV GSWSSLWEIS AHTAEGNVCH 300
  301 GDVINHKTEN SYVYAESGLV TTVGVKDLVV VQTKDAVLIA DRNAVQDVKK VVEQIKADGR 360
  361 HEHRV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	61.522879
Match:	2cu2A
Description:	No description for 2cu2A was found.

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.25720704697246	bayes_pls_golite062009
transferase activity, transferring hexosyl groups	2.04393180556087	bayes_pls_golite062009
transferase activity	1.67251862595728	bayes_pls_golite062009
UDP-glycosyltransferase activity	1.51711005399931	bayes_pls_golite062009
3-deoxy-manno-octulosonate cytidylyltransferase activity	1.31116473821178	bayes_pls_golite062009
cytidylyltransferase activity	1.30540294475078	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	1.21894113759929	bayes_pls_golite062009
UDP-N-acetylglucosamine diphosphorylase activity	0.696745721981411	bayes_pls_golite062009
nucleotidyltransferase activity	0.67147527259372	bayes_pls_golite062009
uridylyltransferase activity	0.54930147038803	bayes_pls_golite062009
acetylgalactosaminyltransferase activity	0.48277064848483	bayes_pls_golite062009
mannose-phosphate guanylyltransferase activity	0.38929738612511	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.280335197569099	bayes_pls_golite062009
glucose-1-phosphate thymidylyltransferase activity	0.204810937394121	bayes_pls_golite062009
guanylyltransferase activity	0.14847697203788	bayes_pls_golite062009
polypeptide N-acetylgalactosaminyltransferase activity	0.10541627748542	bayes_pls_golite062009
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity	0.00302319544700058	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [366-478]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HREVYRPWGK YDSIDAGDRY QVKRITVKPG EGLSVQMHHH RAEHWVVVAG TAKVTIDGDI  60
   61 KLLGENESIY IPLGATHCLE NPGKIPLDLI EVRSGSYLEE DDVVRFADRY GRV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	4.69897
Match:	2pfwA
Description:	No description for 2pfwA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: