YRC Public Data Repository - Protein Structure Prediction

Protein:	INTA_ECOLI
Organism:	Escherichia coli
Length:	413 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for INTA_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|75857323, gi\|... - gi\|75857323\|ref\|ZP_00764939.1\| COG0582: Integrase [Vibrio sp. Ex25], gi\|254228629\|ref\|ZP_04922053.1\|...	299.0	[0..1]	[411..1]
tr\|D7HF28\|D7HF28... - Integrase OS=Vibrio cholerae RC385 GN=VCRC385_00574 PE=4 SV=1 gi\|150421294, gi... - gi\|75822961\|ref\|ZP_00752506.1\| COG0582: Integrase [Vibrio cholerae RC385], gi\|254222126\|ref\|ZP_04915...	294.0	[0..1]	[412..1]
gi\|9655299, gi\|1... - gi\|9655299\|gb\|AAF94009.1\| integrase, phage family [Vibrio cholerae O1 biovar El Tor str. N16961], gi... gi\|1100883, gi\|4... - gi\|498253\|gb\|AAC44230.1\| integrase, gi\|13377568\|gb\|AAK20803.1\|AF325734_29 integrase [Vibrio cholerae... gi\|229344622, gi... - gi\|229517907\|ref\|ZP_04407351.1\| phage integrase [Vibrio cholerae RC9], gi\|229344622\|gb\|EEO09596.1\| p... gi\|498253, gi\|14... - gi\|498253\|gb\|AAC44230.1\| integrase, gi\|227117217\|ref\|YP_002819113.1\| integrase, phage family [Vibrio... gi\|121550043, gi... - gi\|121585680\|ref\|ZP_01675475.1\| integrase, phage family [Vibrio cholerae 2740-80], gi\|121550043\|gb\|E... gi\|153224615, gi... - gi\|153224615\|ref\|ZP_01954522.1\| integrase, phage family [Vibrio cholerae MAK 757], gi\|124117544\|gb\|E... gi\|121631470, gi... - gi\|121725988\|ref\|ZP_01679287.1\| integrase, phage family [Vibrio cholerae V52], gi\|121631470\|gb\|EAX63... gi\|153818037, gi... - gi\|153818037\|ref\|ZP_01970704.1\| integrase, phage family [Vibrio cholerae NCTC 8457], gi\|126511383\|gb... gi\|254843689, gi... - gi\|254847984\|ref\|ZP_05237334.1\| integrase [Vibrio cholerae MO10], gi\|254843689\|gb\|EET22103.1\| integr... gi\|227081023, gi... - gi\|227081023\|ref\|YP_002809574.1\| integrase, phage family [Vibrio cholerae M66-2], gi\|227008911\|gb\|AC... gi\|229350751, gi... - gi\|229510786\|ref\|ZP_04400265.1\| phage integrase [Vibrio cholerae B33], gi\|229350751\|gb\|EEO15692.1\| p... gi\|229357766, gi... - gi\|229505543\|ref\|ZP_04395053.1\| phage integrase [Vibrio cholerae BX 330286], gi\|229357766\|gb\|EEO2268...	293.0	[0..1]	[410..1]
gi\|82496090, gi\|... - gi\|82496090\|ref\|ZP_00881661.1\| integrase, phage family [Shewanella sp. MR-4], gi\|82405894\|gb\|EAP4656...	293.0	[0..1]	[413..1]
gi\|86146771, gi\|... - gi\|86146771\|ref\|ZP_01065091.1\| site-specific recombinase, phage integrase family protein [Vibrio sp....	291.0	[0..1]	[413..1]
gi\|37197485, gi\|... - gi\|37678744\|ref\|NP_933353.1\| phage integrase [Vibrio vulnificus YJ016], gi\|37197485\|dbj\|BAC93324.1\| ...	290.0	[0..1]	[408..1]
gi\|24373045, gi\|... - gi\|24373045\|ref\|NP_717087.1\| phage integrase family site specific recombinase [Shewanella oneidensis... SO1471 - site-specific recombinase phage integrase family	288.0	[0..1]	[413..1]
gi\|49612200, gi\|... - gi\|50121674\|ref\|YP_050841.1\| prophage integrase [Pectobacterium atrosepticum SCRI1043], gi\|49612200\|...	287.0	[0..1]	[412..1]
gi\|75514471, gi\|... - gi\|75514471\|ref\|ZP_00736749.1\| COG0582: Integrase [Escherichia coli 53638], gi\|188492442\|ref\|ZP_0299...	287.0	[0..1]	[412..1]

Back

Predicted Domain #1

Region A:
Residues: [1-413]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MARKTKPLTD TEIKAAKPKD ADYQLYDGDG LTLLIKSSGS KLWQFRYYRP LTKQRTKQSF  60
   61 GAYPAVSLSD ARKLRAESKV LLAKDIDPQE HQKEQVRNSQ EAKTNTFLLV AERWWNVKKT 120
  121 SVTEDYADDI WRSLERDIFP AIGDISITEI KAHTLVKAVQ PVQARGALET VRRLCQRINE 180
  181 VMIYAQNTGL IDAVPSVNIG KAFEKPQKKN MPSIRPDQLP QLMHTMRTAS ISMSTRCLFM 240
  241 WQLLTITRPA EAAEARWDEI DFNASEWKIP AARMKMNRDH TVPLSDGALA ILEMMKPLSG 300
  301 GREFIFPSRI KPNQPMNSQT VNAALKRAGL GGVLVSHGLR SIASTALNEE GFPPDVIEAA 360
  361 LAHVDKNEVR RAYNRSDYLE QRRPMMQWWA DLVKAADSGS IVLTHLSKIR LVG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	21.39794
Match:	1z1bA
Description:	Crystal structure of a lambda integrase dimer bound to a COC' core site
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
structure-specific DNA binding	2.96794540657137	bayes_pls_golite062009
chromatin binding	2.66956311972752	bayes_pls_golite062009
catalytic activity	1.85476765215403	bayes_pls_golite062009
double-stranded DNA binding	1.47056442077417	bayes_pls_golite062009
DNA binding	1.08208472364243	bayes_pls_golite062009
nucleic acid binding	1.01945666037816	bayes_pls_golite062009
sequence-specific DNA binding	0.88630365094839	bayes_pls_golite062009
binding	0.849061082531999	bayes_pls_golite062009
methyl-CpG binding	0.644006146507516	bayes_pls_golite062009
transcription regulator activity	0.433129028335043	bayes_pls_golite062009
protein binding	0.391840757563427	bayes_pls_golite062009
DNA secondary structure binding	0.32168641878414	bayes_pls_golite062009
transcription factor activity	0.135216468398819	bayes_pls_golite062009
transcription factor binding	0.0858654055973298	bayes_pls_golite062009
four-way junction DNA binding	0.0788334929658094	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: