YRC Public Data Repository - Protein Structure Prediction

Protein:	IF3_ECOLI
Organism:	Escherichia coli
Length:	180 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for IF3_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|71369942, gi\|... - gi\|71369942\|ref\|ZP_00660335.1\| Initiation factor 3 [Nocardioides sp. JS614], gi\|71154334\|gb\|EAO04868...	238.0	[0..9]	[180..132]
gi\|56381095, gi\|... - gi\|56421253\|ref\|YP_148571.1\| translation initiation factor IF-3 [Geobacillus kaustophilus HTA426], g...	232.0	[0..2]	[177..61]
gi\|85702892, gi\|... - gi\|85702892\|ref\|ZP_01033996.1\| translation initiation factor [Roseovarius sp. 217], gi\|85671820\|gb\|E...	229.0	[0..2]	[179..41]
IF3_PROHU - Translation initiation factor IF-3 OS=Proteus hauseri GN=infC PE=3 SV=1 IF3_PROVU - Translation initiation factor IF-3 OS=Proteus vulgaris GN=infC PE=3 SV=1	229.0	[0..1]	[179..1]
gi\|49481334, gi\|... - gi\|49481334\|ref\|YP_038621.1\| translation initiation factor IF-3 [Bacillus thuringiensis serovar konk... gi\|225789540, gi... - gi\|225866552\|ref\|YP_002751930.1\| translation initiation factor IF-3 [Bacillus cereus 03BB102], gi\|22... gi\|52140934, gi\|... - gi\|52140934\|ref\|YP_085896.1\| translation initiation factor IF-3 [Bacillus cereus E33L], gi\|51974403\|... gi\|42739682, gi\|... - gi\|42783752\|ref\|NP_980999.1\| translation initiation factor IF-3 [Bacillus cereus ATCC 10987], gi\|427... gi\|49181393, gi\|... - gi\|49187466\|ref\|YP_030718.1\| translation initiation factor IF-3 [Bacillus anthracis str. Sterne], gi... gi\|254741721 - gi\|254741721\|ref\|ZP_05199408.1\| translation initiation factor IF-3 [Bacillus anthracis str. Kruger B... gi\|254736683 - gi\|254736683\|ref\|ZP_05194389.1\| translation initiation factor IF-3 [Bacillus anthracis str. Western ... gi\|229602129, gi... - gi\|229602129\|ref\|YP_002868854.1\| translation initiation factor IF-3 [Bacillus anthracis str. A0248],... gi\|222098037, gi... - gi\|222098037\|ref\|YP_002532094.1\| translation initiation factor IF-3 [Bacillus cereus Q1], gi\|2212420... gi\|177653087, gi... - gi\|177653087\|ref\|ZP_02935374.1\| translation initiation factor IF-3 [Bacillus anthracis str. A0174], ... gi\|170126369, gi... - gi\|170708689\|ref\|ZP_02899127.1\| translation initiation factor IF-3 [Bacillus anthracis str. A0389], ... gi\|118418948, gi... - gi\|118479723\|ref\|YP_896874.1\| translation initiation factor IF-3 [Bacillus thuringiensis str. Al Hak...	228.0	[0..2]	[180..18]
gi\|90204319, gi\|... - gi\|90204319\|ref\|ZP_01206963.1\| Initiation factor 3 [Mycobacterium vanbaalenii PYR-1], gi\|90197079\|gb...	227.0	[0..8]	[178..40]
gi\|178468214, gi... - gi\|182439698\|ref\|YP_001827417.1\| translation initiation factor IF-3 [Streptomyces griseus subsp. gri... gi\|62896304 - gi\|62896304\|emb\|CAH94290.1\| translation initiation factor IF-3 [Streptomyces griseus subsp. griseus]	227.0	[0..8]	[180..19]
gi\|92434111, gi\|... - gi\|92908091\|ref\|ZP_01276870.1\| Initiation factor 3 [Mycobacterium sp. JLS], gi\|92434111\|gb\|EAS93443....	227.0	[0..8]	[178..68]
gi\|92912923, gi\|... - gi\|92912923\|ref\|ZP_01281553.1\| Initiation factor 3 [Mycobacterium sp. KMS], gi\|92443469\|gb\|EAT01306....	226.0	[0..8]	[178..68]
gi\|67986973, gi\|... - gi\|69286435\|ref\|ZP_00617483.1\| Initiation factor 3 [Kineococcus radiotolerans SRS30216], gi\|67986973...	226.0	[0..12]	[177..84]

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Predicted Domain #1

Region A:
Residues: [1-86]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKGGKRVQTA RPNRINGEIR AQEVRLTGLE GEQLGIVSLR EALEKAEEAG VDLVEISPNA  60
   61 EPPVCRIMDY GKFLYEKSKS SKEQKK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	22.154902
Match:	1tifA
Description:	TRANSLATION INITIATION FACTOR 3 N-TERMINAL DOMAIN
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
translation initiation factor activity	5.47485713101079	bayes_pls_golite062009
translation regulator activity	1.62528736558737	bayes_pls_golite062009
translation factor activity, nucleic acid binding	1.60662288414996	bayes_pls_golite062009
binding	1.47561914415547	bayes_pls_golite062009
nucleic acid binding	1.12320467511263	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [87-180]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KQKVIQVKEI KFRPGTDEGD YQVKLRSLIR FLEEGDKAKI TLRFRGREMA HQQIGMEVLN  60
   61 RVKDDLQELA VVESFPTKIE GRQMIMVLAP KKKQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	26.154902
Match:	2ifeA
Description:	Translation initiation factor IF3, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
translation initiation factor activity	8.09269133854598	bayes_pls_golite062009
translation regulator activity	4.19718241948497	bayes_pls_golite062009
translation factor activity, nucleic acid binding	4.18160226822061	bayes_pls_golite062009
nucleic acid binding	3.21583663075334	bayes_pls_golite062009
binding	2.86350131209009	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: