YRC Public Data Repository - Protein Structure Prediction

Protein:	ICC_ECOLI
Organism:	Escherichia coli
Length:	275 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ICC_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|197364053, gi... - gi\|197364053\|ref\|YP_002143690.1\| cyclic 3',5'-adenosine monophosphate phosphodiesterase [Salmonella ... gi\|56415124, gi\|... - gi\|56415124\|ref\|YP_152199.1\| cyclic 3',5'-adenosine monophosphate phosphodiesterase [Salmonella ente...	214.0	[0..1]	[275..1]
gi\|213021680 - gi\|213021680\|ref\|ZP_03336127.1\| cyclic 3',5'-adenosine monophosphate phosphodiesterase [Salmonella e... gi\|206710245, gi... - gi\|207858442\|ref\|YP_002245093.1\| cyclic 3',5'-adenosine monophosphate phosphodiesterase [Salmonella ... gi\|213419640 - gi\|213419640\|ref\|ZP_03352706.1\| cyclic 3',5'-adenosine monophosphate phosphodiesterase [Salmonella e... gi\|213052524 - gi\|213052524\|ref\|ZP_03345402.1\| cyclic 3',5'-adenosine monophosphate phosphodiesterase [Salmonella e... gi\|198242752, gi... - gi\|198242752\|ref\|YP_002217163.1\| protein icc [Salmonella enterica subsp. enterica serovar Dublin str... gi\|29139079, gi\|... - gi\|29143445\|ref\|NP_806787.1\| cyclic 3',5'-adenosine monophosphate phosphodiesterase [Salmonella ente... gi\|16761958 - gi\|16761958\|ref\|NP_457575.1\| cyclic 3',5'-adenosine monophosphate phosphodiesterase [Salmonella ente... gi\|214001842 - gi\|214001842\|ref\|ZP_03412577.1\| cyclic 3',5'-adenosine monophosphate phosphodiesterase [Salmonella e... gi\|25752530, gi\|... - gi\|25752530\|pir\|\|AG0889 3',5'-cyclic-nucleotide phosphodiesterase (EC 3.1.4.17) cpdA-type STY3361 [s... gi\|213615570 - gi\|213615570\|ref\|ZP_03371396.1\| cyclic 3',5'-adenosine monophosphate phosphodiesterase [Salmonella e... gi\|213424343 - gi\|213424343\|ref\|ZP_03357167.1\| cyclic 3',5'-adenosine monophosphate phosphodiesterase [Salmonella e... gi\|213855669 - gi\|213855669\|ref\|ZP_03383909.1\| cyclic 3',5'-adenosine monophosphate phosphodiesterase [Salmonella e... gi\|213645892 - gi\|213645892\|ref\|ZP_03375945.1\| cyclic 3',5'-adenosine monophosphate phosphodiesterase [Salmonella e...	214.0	[0..1]	[275..1]
gi\|204928376, gi... - gi\|204928376\|ref\|ZP_03219576.1\| protein icc [Salmonella enterica subsp. enterica serovar Javiana str... gi\|224584984, gi... - gi\|224584984\|ref\|YP_002638783.1\| hypothetical protein SPC_3257 [Salmonella enterica subsp. enterica ... gi\|197264530, gi... - gi\|197264530\|ref\|ZP_03164604.1\| protein icc [Salmonella enterica subsp. enterica serovar Saintpaul s... gi\|199604271, gi... - gi\|200387173\|ref\|ZP_03213785.1\| protein icc [Salmonella enterica subsp. enterica serovar Virchow str... gi\|194711140, gi... - gi\|194735638\|ref\|YP_002116138.1\| protein icc [Salmonella enterica subsp. enterica serovar Schwarzeng... gi\|197215069, gi... - gi\|197251366\|ref\|YP_002148110.1\| protein icc [Salmonella enterica subsp. enterica serovar Agona str.... gi\|194404248, gi... - gi\|194445585\|ref\|YP_002042450.1\| protein icc [Salmonella enterica subsp. enterica serovar Newport st... gi\|194447552, gi... - gi\|194447552\|ref\|YP_002047180.1\| cyclic 3',5'-adenosine monophosphate phosphodiesterase [Salmonella ... gi\|195633561, gi... - gi\|195633561\|gb\|EDX51975.1\| protein icc [Salmonella enterica subsp. enterica serovar Newport str. SL... gi\|205343528, gi... - gi\|205343528\|gb\|EDZ30292.1\| protein icc [Salmonella enterica subsp. enterica serovar Weltevreden str... gi\|238909984 - gi\|238909984\|ref\|ZP_04653821.1\| cyclic 3',5'-adenosine monophosphate phosphodiesterase [Salmonella e... gi\|205337766, gi... - gi\|205337766\|gb\|EDZ24530.1\| protein icc [Salmonella enterica subsp. enterica serovar Heidelberg str.... gi\|205348326, gi... - gi\|205348326\|gb\|EDZ34957.1\| protein icc [Salmonella enterica subsp. enterica serovar Hadar str. RI_0... gi\|205333904, gi... - gi\|205333904\|gb\|EDZ20668.1\| protein icc [Salmonella enterica subsp. enterica serovar Kentucky str. C... gi\|168238138, gi... - gi\|197288971\|gb\|EDY28342.1\| protein icc [Salmonella enterica subsp. enterica serovar Schwarzengrund ... gi\|205323316, gi... - gi\|205323316\|gb\|EDZ11155.1\| protein icc [Salmonella enterica subsp. enterica serovar Saintpaul str. ... gi\|205331275, gi... - gi\|205331275\|gb\|EDZ18039.1\| protein icc [Salmonella enterica subsp. enterica serovar 4,[5],12:i:- st... gi\|161365536, gi... - gi\|161616172\|ref\|YP_001590137.1\| cyclic 3',5'-adenosine monophosphate phosphodiesterase [Salmonella ... lcl\|NC_016856.1_... - [gene=icc] [protein=cyclic 3',5'-adenosine monophosphate phosphodiesterase] [protein_id=YP_005239355... gi\|16766483, gi\|... - gi\|16766483\|ref\|NP_462098.1\| cyclic 3',5'-adenosine monophosphate phosphodiesterase [Salmonella typh... gi\|62129330, gi\|... - gi\|62181697\|ref\|YP_218114.1\| cyclic 3',5'-adenosine monophosphate phosphodiesterase [Salmonella ente...	213.0	[0..1]	[275..1]
gi\|229837348, gi... - gi\|229837348\|ref\|ZP_04457511.1\| 3',5'-cyclic-nucleotide phosphodiesterase [Yersinia pestis Pestoides... gi\|167470307 - gi\|167470307\|ref\|ZP_02335011.1\| cyclic 3',5'-adenosine monophosphate phosphodiesterase [Yersinia pes... gi\|167055852, gi... - gi\|167425089\|ref\|ZP_02316842.1\| Ser/Thr protein phosphatase family protein [Yersinia pestis biovar M... gi\|229842892, gi... - gi\|229842892\|ref\|ZP_04463044.1\| 3',5'-cyclic-nucleotide phosphodiesterase [Yersinia pestis biovar Or... gi\|167418820, gi... - gi\|167418820\|ref\|ZP_02310573.1\| Ser/Thr protein phosphatase family protein [Yersinia pestis biovar O... gi\|229840560, gi... - gi\|229840560\|ref\|ZP_04460719.1\| 3',5'-cyclic-nucleotide phosphodiesterase [Yersinia pestis biovar Or... gi\|229682226, gi... - gi\|229900887\|ref\|ZP_04516011.1\| 3',5'-cyclic-nucleotide phosphodiesterase [Yersinia pestis Nepal516]... gi\|25752532 - pir\|\|AE0082 3',5'-cyclic-nucleotide phosphodiesterase (EC 3.1.4.17) cpdA-type [similarity] - Yersini... gi\|218927859, gi... - gi\|218927859\|ref\|YP_002345734.1\| cyclic 3',5'-adenosine monophosphate phosphodiesterase [Yersinia pe... gi\|167399027, gi... - gi\|167399027\|ref\|ZP_02304551.1\| Ser/Thr protein phosphatase family protein [Yersinia pestis biovar A... gi\|45442744, gi\|... - gi\|45442744\|ref\|NP_994283.1\| cyclic 3',5'-adenosine monophosphate phosphodiesterase [Yersinia pestis... gi\|166206809, gi... - gi\|166212063\|ref\|ZP_02238098.1\| Ser/Thr protein phosphatase family protein [Yersinia pestis biovar A... gi\|166008829, gi... - gi\|166008829\|ref\|ZP_02229727.1\| Ser/Thr protein phosphatase family protein [Yersinia pestis biovar A... gi\|150260302, gi... - gi\|150260302\|ref\|ZP_01917030.1\| cyclic 3',5'-adenosine monophosphate phosphodiesterase [Yersinia pes... gi\|165923273, gi... - gi\|165925073\|ref\|ZP_02220905.1\| Ser/Thr protein phosphatase family protein [Yersinia pestis biovar O...	212.0	[0..1]	[275..1]
gi\|22127387, gi\|... - gi\|22127387\|ref\|NP_670810.1\| cyclic 3',5'-adenosine monophosphate phosphodiesterase [Yersinia pestis...	210.0	[0..1]	[275..11]
gi\|145597758, gi... - gi\|145597758\|ref\|YP_001161834.1\| cyclic 3',5'-adenosine monophosphate phosphodiesterase [Yersinia pe... gi\|77636086, gi\|... - gi\|77636086\|ref\|ZP_00798163.1\| COG1409: Predicted phosphohydrolases [Yersinia pestis Angola], gi\|162...	208.0	[0..1]	[275..25]
Q665W3\|Q665W3_YERPS - Icc protein homologue - Yersinia pseudotuberculosis gi\|77630402, gi\|... - gi\|77630402\|ref\|ZP_00792988.1\| COG1409: Predicted phosphohydrolases [Yersinia pseudotuberculosis IP ... gi\|51590977, gi\|... - gi\|51597695\|ref\|YP_071886.1\| cyclic 3',5'-adenosine monophosphate phosphodiesterase [Yersinia pseudo... gi\|186896836, gi... - gi\|186896836\|ref\|YP_001873948.1\| cyclic 3',5'-adenosine monophosphate phosphodiesterase [Yersinia ps...	208.0	[0..1]	[275..25]
gi\|170521114, gi... - gi\|170683396\|ref\|YP_001745306.1\| protein icc [Escherichia coli SMS-3-5], gi\|170521114\|gb\|ACB19292.1\|... gi\|218366886, gi... - gi\|218560117\|ref\|YP_002393030.1\| cyclic 3',5'-adenosine monophosphate phosphodiesterase [Escherichia... gi\|190907179, gi... - gi\|75240501\|ref\|ZP_00724429.1\| COG1409: Predicted phosphohydrolases [Escherichia coli F11], gi\|19117... gi\|26249609, gi\|... - gi\|26249609\|ref\|NP_755649.1\| cyclic 3',5'-adenosine monophosphate phosphodiesterase [Escherichia col... gi\|91074032, gi\|... - gi\|91212458\|ref\|YP_542444.1\| cyclic 3',5'-adenosine monophosphate phosphodiesterase [Escherichia col... gi\|227835147, gi... - gi\|227887751\|ref\|ZP_04005556.1\| phosphohydrolase [Escherichia coli 83972], gi\|227835147\|gb\|EEJ45613.... gi\|226899249, gi... - gi\|237706209\|ref\|ZP_04536690.1\| icc protein [Escherichia sp. 3_2_53FAA], gi\|226899249\|gb\|EEH85508.1\|...	208.0	[0..1]	[275..1]
gi\|254289731, gi... - gi\|254289731\|ref\|YP_003055479.1\| cyclic 3',5'-adenosine monophosphate phosphodiesterase [Escherichia... gi\|242378584, gi... - gi\|251786311\|ref\|YP_003000615.1\| hypothetical protein B21_02854 [Escherichia coli BL21], gi\|24237858... gi\|253974882, gi... - gi\|254162981\|ref\|YP_003046089.1\| cyclic 3',5'-adenosine monophosphate phosphodiesterase [Escherichia... gi\|194424286, gi... - gi\|83587527\|ref\|ZP_00926154.1\| COG1409: Predicted phosphohydrolases [Escherichia coli 101-1], gi\|194...	207.0	[0..1]	[275..1]
gi\|24114333, gi\|... - gi\|24114333\|ref\|NP_708843.1\| cyclic 3',5'-adenosine monophosphate phosphodiesterase [Shigella flexne... gi\|30042639, gi\|... - gi\|30064382\|ref\|NP_838553.1\| cyclic 3',5'-adenosine monophosphate phosphodiesterase [Shigella flexne... gi\|110806925, gi... - gi\|110806925\|ref\|YP_690445.1\| cyclic 3',5'-adenosine monophosphate phosphodiesterase [Shigella flexn...	205.0	[0..1]	[275..1]

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Predicted Domain #1

Region A:
Residues: [1-275]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MESLLTLPLA GEARVRILQI TDTHLFAQKH EALLGVNTWE SYQAVLEAIR PHQHEFDLIV  60
   61 ATGDLAQDQS SAAYQHFAEG IASFRAPCVW LPGNHDFQPA MYSALQDAGI SPAKRVFIGE 120
  121 QWQILLLDSQ VFGVPHGELS EFQLEWLERK LADAPERHTL LLLHHHPLPA GCSWLDQHSL 180
  181 RNAGELDTVL AKFPHVKYLL CGHIHQELDL DWNGRRLLAT PSTCVQFKPH CSNFTLDTIA 240
  241 PGWRTLELHA DGTLTTEVHR LADTRFQPDT ASEGY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	31.39794
Match:	2hy1A
Description:	No description for 2hy1A was found.

Predicted functions:

Term	Confidence	Notes
phosphoprotein phosphatase activity	6.45938850813828	bayes_pls_golite062009
phosphatase activity	6.05839828647676	bayes_pls_golite062009
phosphoric ester hydrolase activity	6.05508122107559	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	5.46891274080274	bayes_pls_golite062009
protein serine/threonine phosphatase activity	4.55926485636214	bayes_pls_golite062009
hydrolase activity	4.19812575932308	bayes_pls_golite062009
catalytic activity	1.76896578956606	bayes_pls_golite062009
binding	0.105761960845815	bayes_pls_golite062009
calcium-dependent protein serine/threonine phosphatase activity	0.0863772620665402	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: