YRC Public Data Repository - Protein Structure Prediction

Protein:	HEMY_ECOLI
Organism:	Escherichia coli
Length:	398 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HEMY_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|71675440, gi\|... - gi\|71675440\|ref\|ZP_00673185.1\| TPR repeat:Sel1-like repeat [Trichodesmium erythraeum IMS101], gi\|716...	253.0	[0..59]	[398..1000]
gi\|72383071, gi\|... - gi\|72383071\|ref\|YP_292426.1\| TPR repeat-containing protein [Prochlorococcus marinus str. NATL2A], gi...	251.0	[0..24]	[398..107]
gi\|91079875 - gi\|91079875\|ref\|XP_967579.1\| PREDICTED: similar to CG10392-PB, isoform B [Tribolium castaneum]	249.0	[0..24]	[397..231]
gi\|56967372, gi\|... - gi\|62821820\|ref\|NP_001017359.1\| O-linked N-acetylglucosamine transferase isoform 1 [Danio rerio], gi...	248.0	[0..24]	[397..94]
gi\|5052534 - gi\|5052534\|gb\|AAD38597.1\|AF145622_1 BcDNA.GH04245 [Drosophila melanogaster]	248.0	[0..24]	[397..123]
gi\|66793439, gi\|... - gi\|66793439\|ref\|NP_001019747.1\| UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase [Xe...	247.0	[0..24]	[397..84]
gi\|41719589, gi\|... - gi\|91774230\|ref\|YP_566922.1\| tetratricopeptide protein [Methanococcoides burtonii DSM 6242], gi\|9171...	246.0	[0..63]	[397..189]

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Predicted Domain #1

Region A:
Residues: [1-398]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLKVLLLFVL LIAGIVVGPM IAGHQGYVLI QTDNYNIETS VTGLAIILIL AMVVLFAIEW  60
   61 LLRRIFRTGA HTRGWFVGRK RRRARKQTEQ ALLKLAEGDY QQVEKLMAKN ADHAEQPVVN 120
  121 YLLAAEAAQQ RGDEARANQH LERAAELAGN DTIPVEITRV RLQLARNENH AARHGVDKLL 180
  181 EVTPRHPEVL RLAEQAYIRT GAWSSLLDII PSMAKAHVGD EEHRAMLEQQ AWIGLMDQAR 240
  241 ADNGSEGLRN WWKNQSRKTR HQVALQVAMA EHLIECDDHD TAQQIIIDGL KRQYDDRLLL 300
  301 PIPRLKTNNP EQLEKVLRQQ IKNVGDRPLL WSTLGQSLMK HGEWQEASLA FRAALKQRPD 360
  361 AYDYAWLADA LDRLHKPEEA AAMRRDGLML TLQNNPPQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	48.0
Match:	1w3bA
Description:	The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.02652482814057	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: