YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|153997332, gi...
Organism:	Yersinia pestis CA88-4125
Length:	1538 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|153997332, gi....

Description	E-value	Query Range	Subject Range
gi\|167049867, gi... - gi\|167400499\|ref\|ZP_02306008.1\| glutamate synthase, large subunit [Yersinia pestis biovar Antiqua st... gi\|167426988, gi... - gi\|167426988\|ref\|ZP_02318741.1\| glutamate synthase, large subunit [Yersinia pestis biovar Mediaevali... gi\|165989716, gi... - gi\|166011332\|ref\|ZP_02232230.1\| glutamate synthase, large subunit [Yersinia pestis biovar Antiqua st... gi\|22124048, gi\|... - gi\|22124048\|ref\|NP_667471.1\| glutamate synthase, large subunit [Yersinia pestis KIM], gi\|21956794\|gb... gi\|166211873, gi... - gi\|166211873\|ref\|ZP_02237908.1\| glutamate synthase, large subunit [Yersinia pestis biovar Antiqua st... gi\|162354456, gi... - gi\|162421641\|ref\|YP_001605674.1\| glutamate synthase subunit alpha [Yersinia pestis Angola], gi\|16235... gi\|45438411, gi\|... - gi\|45443542\|ref\|NP_995081.1\| glutamate synthase [NADPH] large chain precursor [Yersinia pestis biova...	0.0	[1..1538]	[1..1535]
gi\|51597794, gi\|... - gi\|51597794\|ref\|YP_071985.1\| Glutamate synthase [NADPH] large chain precursor [Yersinia pseudotuberc... Q665L5\|Q665L5_YERPS - Glutamate synthase [NADPH] large chain - Yersinia pseudotuberculosis	0.0	[1..1538]	[1..1535]
gi\|229687270, gi... - gi\|229899778\|ref\|ZP_04514919.1\| glutamate synthase, large subunit [Yersinia pestis biovar Orientalis... gi\|218930569 - gi\|218930569\|ref\|YP_002348444.1\| glutamate synthase subunit alpha [Yersinia pestis CO92] gi\|89103369 - gi\|89103369\|ref\|ZP_01175950.1\| COG0069: Glutamate synthase domain 2 [Yersinia pestis biovar Oriental... gi\|229695579, gi... - gi\|229839213\|ref\|ZP_04459372.1\| glutamate synthase, large subunit [Yersinia pestis biovar Orientalis...	0.0	[51..1538]	[1..1488]
gi\|153948386, gi... - gi\|77630502\|ref\|ZP_00793088.1\| COG0069: Glutamate synthase domain 2 [Yersinia pseudotuberculosis IP ...	0.0	[51..1538]	[1..1485]
gi\|145597656, gi... - gi\|145597656\|ref\|YP_001161732.1\| glutamate synthase subunit alpha [Yersinia pestis Pestoides F], gi\|... gi\|77635696 - gi\|77635696\|ref\|ZP_00797777.1\| COG0069: Glutamate synthase domain 2 [Yersinia pestis Angola] gi\|161511293 - gi\|161511293\|ref\|NP_995081.2\| glutamate synthase subunit alpha [Yersinia pestis biovar Microtus str.... gi\|229678211, gi... - gi\|229904093\|ref\|ZP_04519204.1\| glutamate synthase, large subunit [Yersinia pestis Nepal516], gi\|229... gi\|108809737, gi... - gi\|108809737\|ref\|YP_653653.1\| glutamate synthase subunit alpha [Yersinia pestis Antiqua], gi\|1087816... gi\|161484918 - gi\|161484918\|ref\|NP_667471.2\| glutamate synthase subunit alpha [Yersinia pestis KIM]	0.0	[51..1538]	[1..1485]
gi\|36787300, gi\|... - gi\|37527864\|ref\|NP_931209.1\| glutamate synthase [NADPH] large chain precursor (glutamate synthase al...	0.0	[30..1538]	[1..1502]
gi\|77977065 - gi\|77977065\|ref\|ZP_00832525.1\| COG0069: Glutamate synthase domain 2 [Yersinia intermedia ATCC 29909]	0.0	[51..1538]	[1..1486]
gi\|77963499 - gi\|77963499\|ref\|ZP_00827308.1\| COG0069: Glutamate synthase domain 2 [Yersinia mollaretii ATCC 43969]	0.0	[51..1538]	[1..1486]
gi\|75209655 - gi\|75209655\|ref\|ZP_00709867.1\| COG0069: Glutamate synthase domain 2 [Escherichia coli B171]	0.0	[18..1538]	[2..1522]
gi\|83585410 - gi\|83585410\|ref\|ZP_00924056.1\| COG0069: Glutamate synthase domain 2 [Escherichia coli 101-1]	0.0	[18..1538]	[2..1522]

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Predicted Domain #1

Region A:
Residues: [1-1538]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRTITRGHWR RAEKQICRKA RVCQPTLSDI NMSFTSWFVR VSQSLGRFTD MLYDQSQERD  60
   61 NCGFGLIAHI EGEPSHKVVR TAIHALARMQ HRGAILADGK TGDGCGLLLQ KPDHFFRMVA 120
  121 EERGWRLAKN YAVGMMFLSQ DEELAKASRR IVEEELQNET LSIVGWREVP TNPDVLGEIA 180
  181 LSSLPRIEQI FVNAPAGWRS RDMERRLFVA RRRIEKRISD KDFYACSFSN LVTIYKGLCM 240
  241 PADLPRFYLD LADLRLESAI CLFHQRFSTN TVPRWPLAQP FRYLAHNGEI NTIAGNRQWA 300
  301 KARAYKFKTP LIPDLQDAAP FVNETGSDSS SLDNMLELFL SGGMDLIRAM RLLVPPAWQN 360
  361 NPDMDTDLRA FFDFNSMHME PWDGPAGIVM SDGRYAACNL DRNGLRPARY VITKDKLITC 420
  421 ASEVGIWDYQ PDEVVEKGRV GPGELMVIDT RSGKILHSAE TDNDLKSRHP YKEWMEKNVK 480
  481 RLVPFEDLPE EQVGSRQLDD SQLETYQKQF GYSNEELDQI IRVLGENGQE ATGSMGDDTP 540
  541 FAVLSSGPRI IYDYFRQQFA QVTNPPIDPL REAHVMSLAT SIGREMNVFC EAEGQAHRLS 600
  601 FKSPILLYSD FQQLTTLEGE HYRADRLDLT FNPAENDLEQ AVLSLCDEAE RKVRDGAVML 660
  661 VLSDRAIAPN RLPVPAPMAV GAIQTRLVDK SLRCDANIIV ETASARDPHH FAVLLGFGAT 720
  721 AIYPYLAYES LAKLVDSQAI DKKYRDVMLN YRNGINKGLY KIMSKMGIST VASYRCAKLF 780
  781 EAVGLHRDLS DLCFQGVVSR IGGASFSDFQ QDLQNLSKRA WLKRKPLDQG GLLKFVHNGE 840
  841 YHAYNPDVVS TLQKAVHSGE YSDYQAYAKL VNERPIATLR DLLAIKPQGT PIPVDQVEPA 900
  901 ESLFKRFDTA AMSIGALSPE AHESLAIAMN SLGGFSNSGE GGEDPARYGT NKVSRIKQVA 960
  961 SGRFGVTPAY LVNADVIQIK VAQGAKPGEG GQLPGDKVTP YIAKLRYSVP GVTLISPPPH1020
 1021 HDIYSIEDLA QLIFDLKQVN PKAMISVKLV SEPGVGTIAT GVAKAYADLI TIAGYDGGTG1080
 1081 ASPLSSVKYA GCPWELGLVE TQQALVANGL RHKIRLQVDG GLKTGVDIVK AAILGAESFG1140
 1141 FGTGPMVALG CKYLRICHLN NCATGVATQD EKLRRDHYHG LPERVVNYFH FIARETRETR1200
 1201 EIMAELGVSQ LVDLIGRTDM LLELDGISAK QNKLDLSPML KTATPHPGKA LYCTESNPPF1260
 1261 DKGLLNKELL SQAEPYIEAK QSKTFYFDIR NTDRSVGAAL SGAIATKHGD QGLATDPIKA1320
 1321 YFSGTAGQSF GVWNAGGVEL MLTGDANDYV GKGMAGGRIA VRPPVGSNFR SHEASIIGNT1380
 1381 CLYGATGGKL FAAGRAGERF AVRNSGAITV VEGIGDNGCE YMTGGIVCVL GRTGINFGAG1440
 1441 MTGGFAYVLD EDGEFRKRVN PELVEVLDVE QLAIHEEHLR GLITEHVQLT GSSRGEEILA1500
 1501 NWPEWVTKFA LVKPKSSDVK ALLGHRSRSA AELRVQAQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	1llwA
Description:	Alpha subunit of glutamate synthase, C-terminal domain; Alpha subunit of glutamate synthase, central and FMN domains; Alpha subunit of glutamate synthase, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
glutamate synthase activity	10.2123323896554	bayes_pls_golite062009
glutamate synthase activity, NADH or NADPH as acceptor	9.64220719720108	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor	8.40816887743017	bayes_pls_golite062009
glutamate synthase (NADPH) activity	7.71666213946687	bayes_pls_golite062009
oxidoreductase activity	2.15666801512485	bayes_pls_golite062009
catalytic activity	1.19663085909195	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors	0.330721070169443	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: