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Catalysis of the reaction: 2 L-glutamate + NAD(P)+ = L-glutamine + 2-oxoglutarate + NAD(P)H + H+. Catalysis of the reaction: 2 L-glutamate + NADP+ = L-glutamine + 2-oxoglutarate + NADPH + H+. Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces NAD+ or NADP. Catalysis of the formation of L-glutamine and 2-oxoglutarate from L-glutamate, using NADH, NADPH or ferredoxin as hydrogen acceptors.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: glutamate synthase (NADPH) activity
Acc: GO:0004355
Aspect: Molecular Function
Desc: Catalysis of the reaction: 2 L-glutamate + NADP+ = L-glutamine + 2-oxoglutarate + NADPH + H+.
Synonyms:
  • glutamate (reduced nicotinamide adenine dinucleotide phosphate) synthase activity
  • L-glutamine:2-oxoglutarate aminotransferase, NADPH oxidizing activity
  • GOGAT activity
  • L-glutamate:NADP+ oxidoreductase (transaminating)
  • NADPH-glutamate synthase activity
  • glutamate synthetase (NADP) activity
  • glutamine-ketoglutaric aminotransferase activity
  • L-glutamate synthetase activity
  • NADPH-linked glutamate synthase
  • glutamine amide-2-oxoglutarate aminotransferase (oxidoreductase, NADP) activity
  • L-glutamate synthase activity
  • NADPH-dependent glutamate synthase activity
Proteins in PDR annotated with:
   This term: 17 [Search]
   Term or descendants: 17 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004355 - glutamate synthase (NADPH) activity (interactive image map)
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Created and Maintained by: Michael Riffle