YRC Public Data Repository - Protein Structure Prediction

Protein:	GLMU_ECOLI
Organism:	Escherichia coli
Length:	456 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GLMU_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|229839827, gi... - gi\|229839827\|ref\|ZP_04459986.1\| bifunctional N-acetyl glucosamine-1-phosphate uridyltransferase/gluc... gi\|229691251, gi... - gi\|229841912\|ref\|ZP_04462068.1\| bifunctional N-acetyl glucosamine-1-phosphate uridyltransferase/gluc... GLMU_YERPS - Bifunctional protein GlmU OS=Yersinia pseudotuberculosis GN=glmU PE=3 SV=1 gi\|229896789, gi... - gi\|229896789\|ref\|ZP_04511952.1\| bifunctional N-acetyl glucosamine-1-phosphate uridyltransferase/gluc... GLMU_YERPA - Bifunctional protein GlmU OS=Yersinia pestis bv. Antiqua (strain Antiqua) GN=glmU PE=3 SV=1 GLMU_YERPB - Bifunctional protein GlmU OS=Yersinia pseudotuberculosis serotype IB (strain PB1/+) GN=glmU PE=3 SV=... GLMU_YERPN - Bifunctional protein GlmU OS=Yersinia pestis bv. Antiqua (strain Nepal516) GN=glmU PE=3 SV=1 gi\|167468117 - gi\|167468117\|ref\|ZP_02332821.1\| UDP-N-acetylglucosamine pyrophosphorylase [Yersinia pestis FV-1] GLMU_YERPY - Bifunctional protein GlmU OS=Yersinia pseudotuberculosis serotype O:3 (strain YPIII) GN=glmU PE=3 SV... GLMU_YERPE - Bifunctional protein GlmU OS=Yersinia pestis GN=glmU PE=1 SV=1 gi\|218931095, gi... - gi\|218931095\|ref\|YP_002348970.1\| bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/gluc... GLMU_YERPS - Bifunctional protein GlmU OS=Yersinia pseudotuberculosis serotype I (strain IP32953) GN=glmU PE=3 SV... GLMU_YERP3 - Bifunctional protein GlmU OS=Yersinia pseudotuberculosis serotype O:1b (strain IP 31758) GN=glmU PE=... gi\|149290355, gi... - gi\|150260947\|ref\|ZP_01917675.1\| UDP-N-acetylglucosamine pyrophosphorylase [Yersinia pestis CA88-4125... GLMU_YERPP - Bifunctional protein GlmU OS=Yersinia pestis (strain Pestoides F) GN=glmU PE=1 SV=1	358.0	[0..1]	[456..1]
gi\|167055499, gi... - gi\|167425485\|ref\|ZP_02317238.1\| UDP-N-acetylglucosamine pyrophosphorylase [Yersinia pestis biovar Me... gi\|167401598, gi... - gi\|167401598\|ref\|ZP_02307092.1\| UDP-N-acetylglucosamine pyrophosphorylase [Yersinia pestis biovar An... gi\|166958254, gi... - gi\|167422862\|ref\|ZP_02314615.1\| UDP-N-acetylglucosamine pyrophosphorylase [Yersinia pestis biovar Or... gi\|165991421, gi... - gi\|166009499\|ref\|ZP_02230397.1\| UDP-N-acetylglucosamine pyrophosphorylase [Yersinia pestis biovar An... gi\|166213193, gi... - gi\|166213193\|ref\|ZP_02239228.1\| UDP-N-acetylglucosamine pyrophosphorylase [Yersinia pestis biovar An... gi\|165926087, gi... - gi\|165926087\|ref\|ZP_02221919.1\| UDP-N-acetylglucosamine pyrophosphorylase [Yersinia pestis biovar Or... gi\|165939981, gi... - gi\|165939981\|ref\|ZP_02228518.1\| UDP-N-acetylglucosamine pyrophosphorylase [Yersinia pestis biovar Or... gi\|21961148, gi\|... - gi\|22128001\|ref\|NP_671424.1\| bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosam... gi\|45443749, gi\|... - gi\|45443749\|ref\|NP_995288.1\| bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosam... gi\|162351013, gi... - gi\|162418198\|ref\|YP_001608470.1\| bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/gluc...	357.0	[0..1]	[456..3]
GLMU_SALTI - Bifunctional protein glmU OS=Salmonella typhi GN=glmU PE=3 SV=1 GLMU_SALTI - Bifunctional protein GlmU OS=Salmonella typhi GN=glmU PE=3 SV=1 gi\|213646875 - gi\|213646875\|ref\|ZP_03376928.1\| bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/gluco... gi\|29139588, gi\|... - gi\|29143952\|ref\|NP_807294.1\| bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosam... gi\|213427473 - gi\|213427473\|ref\|ZP_03360223.1\| bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/gluco... gi\|213052672 - gi\|213052672\|ref\|ZP_03345550.1\| bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/gluco... gi\|16762464 - gi\|16762464\|ref\|NP_458081.1\| bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosam... gi\|214001321 - gi\|214001321\|ref\|ZP_03412056.1\| bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/gluco... gi\|213852798 - gi\|213852798\|ref\|ZP_03382330.1\| bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/gluco...	353.0	[0..1]	[456..1]
GLMU_SALCH - Bifunctional protein glmU OS=Salmonella choleraesuis GN=glmU PE=3 SV=1 GLMU_SALCH - Bifunctional protein GlmU OS=Salmonella choleraesuis (strain SC-B67) GN=glmU PE=3 SV=1 GLMU_SALCH - Bifunctional protein GlmU OS=Salmonella choleraesuis GN=glmU PE=3 SV=1	351.0	[0..1]	[456..1]
gi\|77634107 - gi\|77634107\|ref\|ZP_00796215.1\| COG1207: N-acetylglucosamine-1-phosphate uridyltransferase (contains ... gi\|89104506 - gi\|89104506\|ref\|ZP_01177047.1\| COG1207: N-acetylglucosamine-1-phosphate uridyltransferase (contains ... gi\|77630940, gi\|... - gi\|77630940\|ref\|ZP_00793526.1\| COG1207: N-acetylglucosamine-1-phosphate uridyltransferase (contains ...	351.0	[0..6]	[456..1]
GLMU_SALPA - Bifunctional protein GlmU OS=Salmonella paratyphi A GN=glmU PE=3 SV=1 GLMU_SALPK - Bifunctional protein GlmU OS=Salmonella paratyphi A (strain AKU_12601) GN=glmU PE=3 SV=1 GLMU_SALPA - Bifunctional protein GlmU OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=glmU PE=3 SV=1	351.0	[0..1]	[456..1]
GLMU_SALTY - Bifunctional protein GlmU OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=glmU PE... GLMU_SALTY - Bifunctional protein glmU OS=Salmonella typhimurium GN=glmU PE=3 SV=1 gi\|195632226, gi... - gi\|195632226\|gb\|EDX50710.1\| UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyl... GLMU_SALHS - Bifunctional protein GlmU OS=Salmonella heidelberg (strain SL476) GN=glmU PE=3 SV=1 gi\|167995196, gi... - gi\|205327084\|gb\|EDZ13848.1\| UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyl... gi\|205336006, gi... - gi\|205336006\|gb\|EDZ22770.1\| UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyl... GLMU_SALTY - Bifunctional protein GlmU OS=Salmonella typhimurium GN=glmU PE=3 SV=1 lcl\|NC_016856.1_... - [gene=glmU] [protein=bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-ph...	351.0	[0..1]	[456..1]
gi\|25317116 - gi\|25317116\|pir\|\|A86059 hypothetical protein glmU [imported] - Escherichia coli (strain O157:H7, su... gi\|12518587, gi\|... - gi\|15804330\|ref\|NP_290369.1\| bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosam...	350.0	[0..1]	[456..1]
gi\|77977938 - gi\|77977938\|ref\|ZP_00833375.1\| COG1207: N-acetylglucosamine-1-phosphate uridyltransferase (contains ...	349.0	[0..6]	[456..1]
GLMU_ECOUT - Bifunctional protein GlmU OS=Escherichia coli (strain UTI89 / UPEC) GN=glmU PE=3 SV=1 GLMU_ECOK1 - Bifunctional protein GlmU OS=Escherichia coli O1:K1 / APEC GN=glmU PE=3 SV=1 GLMU_ECO45 - Bifunctional protein GlmU OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=glmU PE=3 SV=1 gi\|237703531, gi... - gi\|237703531\|ref\|ZP_04534012.1\| glmU [Escherichia sp. 3_2_53FAA], gi\|226902795\|gb\|EEH89054.1\| glmU [...	349.0	[0..1]	[456..1]

Back

Predicted Domain #1

Region A:
Residues: [1-456]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLNNAMSVVI LAAGKGTRMY SDLPKVLHTL AGKAMVQHVI DAANELGAAH VHLVYGHGGD  60
   61 LLKQALKDDN LNWVLQAEQL GTGHAMQQAA PFFADDEDIL MLYGDVPLIS VETLQRLRDA 120
  121 KPQGGIGLLT VKLDDPTGYG RITRENGKVT GIVEHKDATD EQRQIQEINT GILIANGADM 180
  181 KRWLAKLTNN NAQGEYYITD IIALAYQEGR EIVAVHPQRL SEVEGVNNRL QLSRLERVYQ 240
  241 SEQAEKLLLA GVMLRDPARF DLRGTLTHGR DVEIDTNVII EGNVTLGHRV KIGTGCVIKN 300
  301 SVIGDDCEIS PYTVVEDANL AAACTIGPFA RLRPGAELLE GAHVGNFVEM KKARLGKGSK 360
  361 AGHLTYLGDA EIGDNVNIGA GTITCNYDGA NKFKTIIGDD VFVGSDTQLV APVTVGKGAT 420
  421 IAAGTTVTRN VGENALAISR VPQTQKEGWR RPVKKK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	96.045757
Match:	1hv9A
Description:	N-acetylglucosamine 1-phosphate uridyltransferase GlmU, C-terminal domain; N-acetylglucosamine 1-phosphate uridyltransferase GlmU, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity	4.85526297527966	bayes_pls_golite062009
O-acyltransferase activity	4.84577168407664	bayes_pls_golite062009
uridylyltransferase activity	2.78377598963895	bayes_pls_golite062009
transferase activity, transferring hexosyl groups	2.55498472336996	bayes_pls_golite062009
UDP-glycosyltransferase activity	2.14294822366154	bayes_pls_golite062009
UTP:glucose-1-phosphate uridylyltransferase activity	2.04683358427931	bayes_pls_golite062009
UTP-monosaccharide-1-phosphate uridylyltransferase activity	1.90086040617591	bayes_pls_golite062009
catalytic activity	1.88676710996045	bayes_pls_golite062009
transferase activity	1.47184463413038	bayes_pls_golite062009
nucleotidyltransferase activity	1.17054423506287	bayes_pls_golite062009
acetylgalactosaminyltransferase activity	1.09519444695756	bayes_pls_golite062009
cytidylyltransferase activity	0.983416157001861	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	0.897978517422275	bayes_pls_golite062009
polypeptide N-acetylgalactosaminyltransferase activity	0.857216989692536	bayes_pls_golite062009
mannosyltransferase activity	0.64885729959093	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.521566400238457	bayes_pls_golite062009
UDP-N-acetylglucosamine diphosphorylase activity	0.513376694534047	bayes_pls_golite062009
mannose-phosphate guanylyltransferase activity	0.2363835251362	bayes_pls_golite062009
guanylyltransferase activity	0.0539392112504681	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: