YRC Public Data Repository - Protein Structure Prediction

Protein:	DNAJ_YERPP
Organism:	Yersinia pestis Pestoides F
Length:	379 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DNAJ_YERPP.

Description	E-value	Query Range	Subject Range
DNAJ_SALCH - Chaperone protein DnaJ OS=Salmonella choleraesuis GN=dnaJ PE=3 SV=3 DNAJ_SALTY - Chaperone protein DnaJ OS=Salmonella typhimurium GN=dnaJ PE=2 SV=2 DNAJ_SALPB - Chaperone protein dnaJ OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=dnaJ PE=3 SV=1 gi\|168234750, gi... - gi\|197292013\|gb\|EDY31363.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar Schw... gi\|205335216, gi... - gi\|205335216\|gb\|EDZ21980.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar Kent... gi\|205331430, gi... - gi\|205331430\|gb\|EDZ18194.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar 4,[5... gi\|167552158, gi... - gi\|205323117\|gb\|EDZ10956.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar Sain... lcl\|NC_016856.1_... - [gene=dnaJ] [protein=chaperone protein DnaJ] [protein_id=YP_005235647.1] [location=13595..14734] DNAJ_SALTI - Chaperone protein DnaJ OS=Salmonella typhi GN=dnaJ PE=3 SV=2 DNAJ_SALTY - Chaperone protein DnaJ OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=dnaJ PE=3 ... DNAJ_SALTI - Chaperone protein dnaJ OS=Salmonella typhi GN=dnaJ PE=2 SV=2 DNAJ_SALTY - Chaperone protein dnaJ OS=Salmonella typhimurium GN=dnaJ PE=2 SV=2 gi\|200386746, gi... - gi\|200386746\|ref\|ZP_03213358.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar ... DNAJ_SALDC - Chaperone protein DnaJ OS=Salmonella dublin (strain CT_02021853) GN=dnaJ PE=3 SV=1 gi\|238910770 - gi\|238910770\|ref\|ZP_04654607.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar ... gi\|197261782, gi... - gi\|197261782\|ref\|ZP_03161856.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar ... DNAJ_SALA4 - Chaperone protein DnaJ OS=Salmonella agona (strain SL483) GN=dnaJ PE=3 SV=1 gi\|213052055 - gi\|213052055\|ref\|ZP_03344933.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar ... DNAJ_SALEP - Chaperone protein DnaJ OS=Salmonella enteritidis PT4 (strain P125109) GN=dnaJ PE=3 SV=1 DNAJ_SALG2 - Chaperone protein DnaJ OS=Salmonella gallinarum (strain 287/91 / NCTC 13346) GN=dnaJ PE=3 SV=1 gi\|204927085, gi... - gi\|204927085\|ref\|ZP_03218287.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar ... gi\|168822157, gi... - gi\|205341422\|gb\|EDZ28186.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar Welt... gi\|168464463, gi... - gi\|195633028\|gb\|EDX51482.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar Newp... gi\|205348796, gi... - gi\|205348796\|gb\|EDZ35427.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar Hada... gi\|168244484, gi... - gi\|205336608\|gb\|EDZ23372.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar Heid... DNAJ_SALSV - Chaperone protein DnaJ OS=Salmonella schwarzengrund (strain CVM19633) GN=dnaJ PE=3 SV=1 gi\|194455583, gi... - gi\|194469219\|ref\|ZP_03075203.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar ... DNAJ_SALHS - Chaperone protein DnaJ OS=Salmonella heidelberg (strain SL476) GN=dnaJ PE=3 SV=1 DNAJ_SALNS - Chaperone protein DnaJ OS=Salmonella newport (strain SL254) GN=dnaJ PE=3 SV=1 gi\|213864898 - gi\|213864898\|ref\|ZP_03387017.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar ... gi\|213647263 - gi\|213647263\|ref\|ZP_03377316.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar ... gi\|213616376 - gi\|213616376\|ref\|ZP_03372202.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar ... gi\|213426531 - gi\|213426531\|ref\|ZP_03359281.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar ... DNAJ_SALPC - Chaperone protein DnaJ OS=Salmonella paratyphi C (strain RKS4594) GN=dnaJ PE=3 SV=1 gi\|214001206 - gi\|214001206\|ref\|ZP_03411941.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar ... gi\|29136180, gi\|... - gi\|29140556\|ref\|NP_803898.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar Typ... gi\|16759006 - gi\|16759006\|ref\|NP_454623.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar Typ... DNAJ_SALPB - Chaperone protein DnaJ OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=dnaJ PE=3 SV=1 DNAJ_SALCH - Chaperone protein DnaJ OS=Salmonella choleraesuis (strain SC-B67) GN=dnaJ PE=3 SV=3 DNAJ_SALCH - Chaperone protein dnaJ OS=Salmonella choleraesuis GN=dnaJ PE=3 SV=3	0.0	[1..379]	[1..379]
gi\|188495716, gi... - gi\|75515606\|ref\|ZP_00737763.1\| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom... gi\|168785065, gi... - gi\|189374927\|gb\|EDU93343.1\| chaperone protein DnaJ [Escherichia coli O157:H7 str. EC869], gi\|1687850... sp\|B7UI60\|DNAJ_ECO27 - Chaperone protein dnaJ OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=dnaJ PE=3 SV=1 DNAJ_SHISS - Chaperone protein DnaJ OS=Shigella sonnei (strain Ss046) GN=dnaJ PE=3 SV=1 gi\|168762775, gi... - gi\|189366928\|gb\|EDU85344.1\| chaperone protein DnaJ [Escherichia coli O157:H7 str. EC4501], gi\|168762... gi\|192956076, gi... - gi\|75234578\|ref\|ZP_00718919.1\| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom... DNAJ_ECOSM - Chaperone protein DnaJ OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=dnaJ PE=3 SV=1 gi\|193065637, gi... - gi\|75256327\|ref\|ZP_00727999.1\| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom... gi\|189379547, gi... - gi\|189379547\|gb\|EDU97963.1\| chaperone protein DnaJ [Escherichia coli O157:H7 str. EC508], gi\|1687979... DNAJ_ECO27 - Chaperone protein DnaJ OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=dnaJ PE=3 SV=1 DNAJ_ECOSE - Chaperone protein DnaJ OS=Escherichia coli (strain SE11) GN=dnaJ PE=3 SV=1 DNAJ_ECOL6 - Chaperone protein DnaJ OS=Escherichia coli O6 GN=dnaJ PE=2 SV=3 DNAJ_ESCF3 - Chaperone protein DnaJ OS=Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73) GN=dn... gi\|217325343, gi... - gi\|217325343\|ref\|ZP_03441427.1\| chaperone protein DnaJ [Escherichia coli O157:H7 str. TW14588], gi\|2... DNAJ_ECOUT - Chaperone protein DnaJ OS=Escherichia coli (strain UTI89 / UPEC) GN=dnaJ PE=3 SV=1 gi\|15829269, gi\|... - gi\|15829269\|ref\|NP_308042.1\| chaperone protein DnaJ [Escherichia coli O157:H7 str. Sakai], gi\|133594... gi\|75229476, gi\|... - gi\|75229476\|ref\|ZP_00716026.1\| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom... gi\|75235742, gi\|... - gi\|75235742\|ref\|ZP_00719906.1\| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom... DNAJ_ECO24 - Chaperone protein DnaJ OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=dnaJ PE=3 SV=1 DNAJ_ECOHS - Chaperone protein DnaJ OS=Escherichia coli O9:H4 (strain HS) GN=dnaJ PE=3 SV=1 gi\|209747186, gi... - pir\|\|G85481 chaperone with DnaK, heat shock protein [imported] - Escherichia coli (strain O157:H7, s... DNAJ_ECO57 - Chaperone protein DnaJ OS=Escherichia coli O157:H7 GN=dnaJ PE=3 SV=3 DNAJ_ECOL6 - Chaperone protein DnaJ OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=dnaJ PE=3 S... DNAJ_ECO45 - Chaperone protein DnaJ OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=dnaJ PE=3 SV=1 gi\|12512693, gi\|... - gi\|15799695\|ref\|NP_285707.1\| chaperone protein DnaJ [Escherichia coli O157:H7 EDL933], gi\|12512693\|g... DNAJ_ECO8A - Chaperone protein DnaJ OS=Escherichia coli O8 (strain IAI1) GN=dnaJ PE=3 SV=1 DNAJ_ECO55 - Chaperone protein DnaJ OS=Escherichia coli (strain 55989 / EAEC) GN=dnaJ PE=3 SV=1 DNAJ_ECO81 - Chaperone protein DnaJ OS=Escherichia coli O81 (strain ED1a) GN=dnaJ PE=3 SV=1 DNAJ_ECOLU - Chaperone protein DnaJ OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) GN=dnaJ PE=3 SV=1 DNAJ_ECO7I - Chaperone protein DnaJ OS=Escherichia coli O7:K1 (strain IAI39 / ExPEC) GN=dnaJ PE=3 SV=1 gi\|227837919, gi... - gi\|227885090\|ref\|ZP_04002895.1\| chaperone protein DnaJ [Escherichia coli 83972], gi\|227837919\|gb\|EEJ... gi\|229560216 - gi\|229560216\|ref\|YP_667956.2\| chaperone protein DnaJ [Escherichia coli 536] gi\|229775981 - gi\|229775981\|ref\|YP_851221.2\| chaperone protein DnaJ [Escherichia coli APEC O1] DNAJ_ECOLC - Chaperone protein DnaJ OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=dnaJ PE=3 SV=1	0.0	[1..379]	[1..376]
DNAJ_SHIBS - Chaperone protein DnaJ OS=Shigella boydii serotype 4 (strain Sb227) GN=dnaJ PE=3 SV=1 DNAJ_SHIB3 - Chaperone protein DnaJ OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=dnaJ PE=3 SV=1	0.0	[1..379]	[1..376]
gi\|83585322, gi\|... - gi\|83585322\|ref\|ZP_00923970.1\| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom... gi\|254286940, gi... - gi\|254286940\|ref\|YP_003052688.1\| chaperone Hsp40, co-chaperone with DnaK [Escherichia coli BL21(DE3)... gi\|251783579, gi... - gi\|251783579\|ref\|YP_002997883.1\| hypothetical protein B21_00015 [Escherichia coli BL21], gi\|24237585... gi\|253972037, gi... - gi\|254160136\|ref\|YP_003043244.1\| chaperone Hsp40, co-chaperone with DnaK [Escherichia coli B str. RE...	0.0	[1..379]	[1..376]
gi\|89106899, gi\|... - gi\|89106899\|ref\|AP_000679.1\| chaperone Hsp40, co-chaperone with DnaK [Escherichia coli str. K-12 sub... DNAJ_ECODH - Chaperone protein DnaJ OS=Escherichia coli (strain K12 / DH10B) GN=dnaJ PE=3 SV=1 DNAJ_ECOLI - Chaperone protein dnaJ (Heat shock protein J) (HSP40) - Escherichia coli EG10240 - chaperone Hsp40, DnaK co-chaperone / DnaK co-chaperone HSP40; DNA-binding protein; stress-related DN... EG10240 - chaperone Hsp40, DnaK co-chaperone / DnaK co-chaperone HSP40; DNA-binding protein; stress-related DN...	0.0	[1..379]	[1..376]
DNAJ_SHIF8 - Chaperone protein DnaJ OS=Shigella flexneri serotype 5b (strain 8401) GN=dnaJ PE=3 SV=1 gi\|30061585, gi\|... - gi\|30061585\|ref\|NP_835756.1\| chaperone protein DnaJ [Shigella flexneri 2a str. 2457T], gi\|30039827\|g...	0.0	[1..379]	[1..376]
gi\|124530383, gi... - gi\|124530383\|ref\|ZP_01701069.1\| chaperone protein DnaJ [Escherichia coli B], gi\|124499274\|gb\|EAY4676... gi\|110640228, gi... - gi\|110640228\|ref\|YP_667956.1\| chaperone protein DnaJ [Escherichia coli 536], gi\|110341820\|gb\|ABG6805...	0.0	[1..379]	[11..386]
DNAJ_SHIDS - Chaperone protein DnaJ OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=dnaJ PE=3 SV=1	0.0	[1..379]	[1..376]
gi\|194429152, gi... - gi\|75209619\|ref\|ZP_00709837.1\| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom...	0.0	[1..379]	[1..376]
gi\|117622308, gi... - gi\|117622308\|ref\|YP_851221.1\| chaperone protein DnaJ [Escherichia coli APEC O1], gi\|115511432\|gb\|ABI... gi\|226902067, gi... - gi\|237704155\|ref\|ZP_04534636.1\| chaperone with DnaK [Escherichia sp. 3_2_53FAA], gi\|226902067\|gb\|EEH...	0.0	[1..379]	[11..386]

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Predicted Domain #1

Region A:
Residues: [1-115]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKRDYYEVL GVSRDAEERE IKKAYKRLAM KFHPDRQSED KNAEEKFKEA KEAYEILTDA  60
   61 QKRAAYDQYG HAAFEQGGMG GGGFGGGGGG ADFSDIFGDV FGDIFGGGRR QQRAS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	25.045757
Match:	1xblA
Description:	NMR STRUCTURE OF THE J-DOMAIN (RESIDUES 2-76) IN THE ESCHERICHIA COLI N-TERMINAL FRAGMENT (RESIDUES 2-108) OF THE MOLECULAR CHAPERONE DNAJ, 20 STRUCTURES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
unfolded protein binding	3.04403163860617	bayes_pls_golite062009
heat shock protein binding	2.17994194200939	bayes_pls_golite062009
binding	2.03854863870179	bayes_pls_golite062009
chaperone binding	1.61155546076854	bayes_pls_golite062009
protein binding	1.35701123337504	bayes_pls_golite062009
transcription regulator activity	1.2131700498174	bayes_pls_golite062009
nucleic acid binding	1.12971478797926	bayes_pls_golite062009
DNA binding	0.8788643398536	bayes_pls_golite062009
Hsp70 protein binding	0.541755903922701	bayes_pls_golite062009
catalytic activity	0.106988907594358	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [116-379]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RGSDLRYNMD LTLEEAVRGV TKEIRIPTLD ECDVCHGSGA KPGSSPVTCP TCHGAGQVQM  60
   61 RQGFFTVQQA CPHCHGRGQI IKDPCNKCHG HGRVEKSKTL SVKIPAGVDT GDRIRLSGEG 120
  121 EAGEHGAPSG DLYVQVQVKA HPIFEREGNN LYCEVPINFA MAALGGEIEV PTLDGRVKLK 180
  181 IPAETQTGKM FRMRGKGVKS VRGGSQGDLL CRVVVETPVS LSEKQKQLLR ELEESFVGAA 240
  241 GEKNSPRAKS FLDGVKKFFD DLTR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	44.69897
Match:	1nltA
Description:	The crystal structure of Hsp40 Ydj1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
protein disulfide isomerase activity	2.4409950647303	bayes_pls_golite062009
intramolecular oxidoreductase activity, transposing S-S bonds	2.4409950647303	bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting keto- and enol-groups	2.23398279564144	bayes_pls_golite062009
binding	2.13705208493215	bayes_pls_golite062009
unfolded protein binding	2.04158808514315	bayes_pls_golite062009
protein binding	1.32690171510656	bayes_pls_golite062009
catalytic activity	0.276917867171685	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: