YRC Public Data Repository - Protein Structure Prediction

Protein:	FOXD1_RAT
Organism:	Rattus norvegicus
Length:	101 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FOXD1_RAT.

Description	E-value	Query Range	Subject Range
gi\|114652732 - gi\|114652732\|ref\|XP_001144389.1\| PREDICTED: forkhead box A1 [Pan troglodytes]	191.0	[0..3]	[100..169]
gi\|60654413 - gi\|60654413\|gb\|AAX29897.1\| forkhead box A1 [synthetic construct]	191.0	[0..3]	[100..170]
gi\|117645444, gi... - gi\|208966288\|dbj\|BAG73158.1\| forkhead box A1 [synthetic construct], gi\|117645562\|emb\|CAL38247.1\| hyp... gi\|24497501, gi\|... - gi\|24497501\|ref\|NP_004487.2\| forkhead box A1 [Homo sapiens], gi\|21707517\|gb\|AAH33890.1\| Forkhead box...	191.0	[0..3]	[100..170]
gi\|19527655 - gi\|19527655\|gb\|AAL89942.1\| SD02951p [Drosophila melanogaster]	191.0	[0..1]	[101..83]
gi\|73963239 - gi\|73963239\|ref\|XP_852354.1\| PREDICTED: similar to forkhead box A1 [Canis familiaris]	191.0	[0..3]	[100..170]
FOXA1_MOUSE - Hepatocyte nuclear factor 3-alpha OS=Mus musculus GN=Foxa1 PE=1 SV=2	191.0	[0..3]	[100..170]
gi\|125811493\|ref... - GA17601-PA [Drosophila pseudoobscura], GA17601 [Drosophila pseudoobscura pseudoobscura] gi\|125811493, gi... - gi\|54637065\|gb\|EAL26468.1\| GA17601 [Drosophila pseudoobscura pseudoobscura], gi\|125811493\|ref\|XP_001...	190.0	[0..1]	[101..71]

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Predicted Domain #1

Region A:
Residues: [1-101]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LVKPPYSYIA LITMAILQSP KKRLTLSEIC EFISGRFPYY REKFPAWQNS IRHNLSLNDC  60
   61 FVKIPREPGN PGKGNYWTLD PESADMFDNG SFLRRRKRFK R

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	42.39794
Match:	2hdcA
Description:	Genesis
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	5.55329976718261	bayes_pls_golite062009
DNA binding	5.08959163553491	bayes_pls_golite062009
nucleic acid binding	4.99681957904233	bayes_pls_golite062009
transcription factor activity	4.33152142980289	bayes_pls_golite062009
transcription repressor activity	3.85678231380989	bayes_pls_golite062009
transcription activator activity	3.70589483230587	bayes_pls_golite062009
sequence-specific DNA binding	3.58179858678904	bayes_pls_golite062009
binding	3.52874320222492	bayes_pls_golite062009
RNA polymerase II transcription factor activity	2.60738445921725	bayes_pls_golite062009
protein binding	1.80415286835431	bayes_pls_golite062009
general RNA polymerase II transcription factor activity	1.2723726467408	bayes_pls_golite062009
specific transcriptional repressor activity	0.96257232341735	bayes_pls_golite062009
transcription factor binding	0.85714789329232	bayes_pls_golite062009
specific RNA polymerase II transcription factor activity	0.66743181561551	bayes_pls_golite062009
transcription corepressor activity	0.322180400748724	bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding	0.23177057841536	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: