YRC Public Data Repository - Protein Structure Prediction

Protein:	FUR_ECOLI
Organism:	Escherichia coli
Length:	148 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FUR_ECOLI.

Description	E-value	Query Range	Subject Range
FUR_SHIFL - Ferric uptake regulation protein OS=Shigella flexneri GN=fur PE=3 SV=1 gi\|24050852, gi\|... - gi\|24112031\|ref\|NP_706541.1\| ferric uptake regulator [Shigella flexneri 2a str. 301], gi\|24050852\|gb...	177.0	[0..1]	[148..1]
gi\|28172774 - gi\|28172774\|emb\|CAD62225.1\| Fur protein [Enterobacter cloacae]	177.0	[0..1]	[148..1]
FUR_KLEPN - Ferric uptake regulation protein OS=Klebsiella pneumoniae GN=fur PE=3 SV=2	175.0	[0..1]	[142..1]
gi\|168240537, gi... - gi\|205340233\|gb\|EDZ26997.1\| ferric uptake regulation protein [Salmonella enterica subsp. enterica se... gi\|168264303, gi... - gi\|205347145\|gb\|EDZ33776.1\| ferric uptake regulation protein [Salmonella enterica subsp. enterica se... gi\|168467758, gi... - gi\|195629224\|gb\|EDX48592.1\| ferric uptake regulation protein [Salmonella enterica subsp. enterica se... gi\|168820186, gi... - gi\|205343196\|gb\|EDZ29960.1\| ferric uptake regulation protein [Salmonella enterica subsp. enterica se... gi\|167553945, gi... - gi\|205321727\|gb\|EDZ09566.1\| ferric uptake regulation protein [Salmonella enterica subsp. enterica se... gi\|167992961, gi... - gi\|205328895\|gb\|EDZ15659.1\| ferric uptake regulation protein [Salmonella enterica subsp. enterica se... lcl\|NC_016856.1_... - [gene=fur] [protein=ferric uptake regulator] [protein_id=YP_005236408.1] [location=complement(756891... gi\|205334771, gi... - gi\|205334771\|gb\|EDZ21535.1\| ferric uptake regulation protein [Salmonella enterica subsp. enterica se... gi\|168236680, gi... - gi\|197290327\|gb\|EDY29683.1\| ferric uptake regulation protein (Ferric uptake regulator) [Salmonella e... gi\|161615087, gi... - gi\|161615087\|ref\|YP_001589052.1\| ferric uptake regulator [Salmonella enterica subsp. enterica serova... gi\|238911637 - gi\|238911637\|ref\|ZP_04655474.1\| ferric uptake regulator [Salmonella enterica subsp. enterica serovar... gi\|16759637 - gi\|16759637\|ref\|NP_455254.1\| ferric uptake regulator [Salmonella enterica subsp. enterica serovar Ty... gi\|213647554 - gi\|213647554\|ref\|ZP_03377607.1\| ferric uptake regulator [Salmonella enterica subsp. enterica serovar... gi\|213864784 - gi\|213864784\|ref\|ZP_03386903.1\| ferric uptake regulator [Salmonella enterica subsp. enterica serovar... gi\|16764063, gi\|... - gi\|16764063\|ref\|NP_459678.1\| ferric uptake regulator [Salmonella typhimurium LT2], gi\|16419201\|gb\|AA... gi\|213978038 - gi\|213978038\|ref\|ZP_03405297.1\| ferric uptake regulator [Salmonella enterica subsp. enterica serovar... gi\|29138221, gi\|... - gi\|29142590\|ref\|NP_805932.1\| ferric uptake regulator [Salmonella enterica subsp. enterica serovar Ty... gi\|214001372 - gi\|214001372\|ref\|ZP_03412107.1\| ferric uptake regulator [Salmonella enterica subsp. enterica serovar... gi\|204930450, gi... - gi\|204930450\|ref\|ZP_03221380.1\| ferric uptake regulation protein [Salmonella enterica subsp. enteric... gi\|213163196 - gi\|213163196\|ref\|ZP_03348906.1\| ferric uptake regulator [Salmonella enterica subsp. enterica serovar... gi\|213428181 - gi\|213428181\|ref\|ZP_03360931.1\| ferric uptake regulator [Salmonella enterica subsp. enterica serovar... gi\|213586325 - gi\|213586325\|ref\|ZP_03368151.1\| ferric uptake regulator [Salmonella enterica subsp. enterica serovar... gi\|197211251, gi... - gi\|197247548\|ref\|YP_002145665.1\| ferric uptake regulation protein [Salmonella enterica subsp. enteri... gi\|197264354, gi... - gi\|197264354\|ref\|ZP_03164428.1\| ferric uptake regulation protein [Salmonella enterica subsp. enteric... gi\|197363110, gi... - gi\|197363110\|ref\|YP_002142747.1\| ferric uptake regulator [Salmonella enterica subsp. enterica serova... gi\|199602474, gi... - gi\|200390029\|ref\|ZP_03216640.1\| ferric uptake regulation protein [Salmonella enterica subsp. enteric... gi\|194404770, gi... - gi\|194446107\|ref\|YP_002039930.1\| ferric uptake regulation protein [Salmonella enterica subsp. enteri... gi\|194449699, gi... - gi\|194449699\|ref\|YP_002044723.1\| ferric uptake regulator [Salmonella enterica subsp. enterica serova... gi\|194472060, gi... - gi\|194472060\|ref\|ZP_03078044.1\| ferric uptake regulation protein [Salmonella enterica subsp. enteric... gi\|194736941, gi... - gi\|194736941\|ref\|YP_002113799.1\| ferric uptake regulation protein [Salmonella enterica subsp. enteri... gi\|62126916, gi\|... - gi\|62179283\|ref\|YP_215700.1\| ferric uptake regulator [Salmonella enterica subsp. enterica serovar Ch... gi\|56128444, gi\|... - gi\|56414187\|ref\|YP_151262.1\| ferric uptake regulator [Salmonella enterica subsp. enterica serovar Pa... gi\|224467047, gi... - gi\|224582520\|ref\|YP_002636318.1\| ferric uptake regulator [Salmonella enterica subsp. enterica serova... gi\|16501929, gi\|... - gi\|25316994\|pir\|\|AB0586 ferric uptake regulation protein [imported] - Salmonella enterica subsp. ent...	175.0	[0..1]	[146..1]
gi\|238725407, gi... - gi\|77976359\|ref\|ZP_00831854.1\| COG0735: Fe2+/Zn2+ uptake regulation proteins [Yersinia intermedia AT...	173.0	[0..1]	[148..1]
gi\|4102783 - gi\|4102783\|gb\|AAD01582.1\| ferric uptake regulation protein [Pectobacterium chrysanthemi]	173.0	[0..1]	[148..1]
gi\|36784720, gi\|... - gi\|37525293\|ref\|NP_928637.1\| ferric uptake regulator [Photorhabdus luminescens subsp. laumondii TTO1...	172.0	[0..1]	[148..1]
Q66DC2\|Q66DC2_YERPS - Ferric uptake regulator - Yersinia pseudotuberculosis gi\|51595471, gi\|... - gi\|51595471\|ref\|YP_069662.1\| ferric uptake regulator [Yersinia pseudotuberculosis IP 32953], gi\|5158... gi\|186894502, gi... - gi\|186894502\|ref\|YP_001871614.1\| ferric uptake regulator [Yersinia pseudotuberculosis PB1/+], gi\|186... gi\|77632087, gi\|... - gi\|77632087\|ref\|ZP_00794673.1\| COG0735: Fe2+/Zn2+ uptake regulation proteins [Yersinia pseudotubercu... gi\|170025213, gi... - gi\|170025213\|ref\|YP_001721718.1\| ferric uptake regulator [Yersinia pseudotuberculosis YPIII], gi\|169...	172.0	[0..1]	[148..1]
gi\|88792643, gi\|... - gi\|90192401\|gb\|AAY28416.2\| ferric uptake regulator [Vibrio alginolyticus], gi\|88792643\|gb\|ABD52297.1... gi\|91225929, gi\|... - gi\|91225929\|ref\|ZP_01260898.1\| ferric uptake regulator [Vibrio alginolyticus 12G01], gi\|91189579\|gb\|...	172.0	[0..1]	[148..1]
FUR_VIBAN - Ferric uptake regulation protein OS=Vibrio anguillarum GN=fur PE=1 SV=1 FUR_VIBA7 - Ferric uptake regulation protein OS=Vibrio anguillarum (strain ATCC 68554 / 775) GN=fur PE=1 SV=1	172.0	[0..1]	[148..1]

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Predicted Domain #1

Region A:
Residues: [1-148]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDNNTALKK AGLKVTLPRL KILEVLQEPD NHHVSAEDLY KRLIDMGEEI GLATVYRVLN  60
   61 QFDDAGIVTR HNFEGGKSVF ELTQQHHHDH LICLDCGKVI EFSDDSIEAR QREIAAKHGI 120
  121 RLTNHSLYLY GHCAEGDCRE DEHAHEGK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	35.69897
Match:	1mzbA
Description:	Ferric uptake regulator
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	4.51306541310201	bayes_pls_golite062009
DNA binding	4.12876602944304	bayes_pls_golite062009
nucleic acid binding	4.12610640813616	bayes_pls_golite062009
transcription factor activity	3.36245551077648	bayes_pls_golite062009
binding	2.88885372623841	bayes_pls_golite062009
sequence-specific DNA binding	1.57171040630767	bayes_pls_golite062009
transcription activator activity	1.46816740214642	bayes_pls_golite062009
transcription repressor activity	1.35320462873179	bayes_pls_golite062009
RNA polymerase II transcription factor activity	0.77269240913386	bayes_pls_golite062009
protein binding	0.753698599635855	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: