YRC Public Data Repository - Protein Structure Prediction

Protein:	FIXB_ECOLI
Organism:	Escherichia coli
Length:	313 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FIXB_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|48734683, gi\|... - gi\|48734683\|gb\|AAH71394.1\| Electron-transfer-flavoprotein, alpha polypeptide [Danio rerio], gi\|38707...	321.0	[0..1]	[313..17]
gi\|146273985, gi... - gi\|98661154\|dbj\|GAA01765.1\| unnamed protein product [Pelotomaculum thermopropionicum SI], gi\|1476778...	315.0	[0..5]	[313..3]
gi\|66526470 - gi\|66526470\|ref\|XP_624102.1\| PREDICTED: similar to walrus CG8996-PB, isoform B isoform 1 [Apis melli...	314.0	[0..1]	[311..18]
gi\|126698385, gi... - gi\|126698385\|ref\|YP_001087282.1\| electron transfer flavoprotein alpha-subunit [Clostridium difficile...	312.0	[0..1]	[313..12]
gi\|90575685, gi\|... - gi\|90575685\|ref\|ZP_01232162.1\| hypothetical protein CdifQ_02000844 [Clostridium difficile QCD-32g58]...	312.0	[0..1]	[313..12]
gi\|28317158 - gi\|28317158\|gb\|AAD46853.2\|AF160913_1 LD07532p [Drosophila melanogaster]	311.0	[0..1]	[311..25]
gi\|84782647 - gi\|84782647\|gb\|ABC61672.1\| cxpwmw03 [Periplaneta americana]	310.0	[0..1]	[311..19]
gi\|89267890, gi\|... - gi\|89267890\|emb\|CAJ83318.1\| electron transferring flavoprotein, alpha polypeptide [Xenopus tropicali...	310.0	[0..1]	[313..16]
gi\|53134324, gi\|... - gi\|71895681\|ref\|NP_001025714.1\| electron transfer flavoprotein, alpha polypeptide [Gallus gallus], g...	309.0	[0..1]	[303..17]
gi\|91075966 - gi\|91075966\|ref\|XP_969306.1\| PREDICTED: similar to cxpwmw03 [Tribolium castaneum]	309.0	[0..1]	[311..17]

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Predicted Domain #1

Region A:
Residues: [1-313]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNTFSQVWVF SDTPSRLPEL MNGAQALANQ INTFVLNDAD GAQAIQLGAN HVWKLNGKPD  60
   61 DRMIEDYAGV MADTIRQHGA DGLVLLPNTR RGKLLAAKLG YRLKAAVSND ASTVSVQDGK 120
  121 ATVKHMVYGG LAIGEERIAT PYAVLTISSG TFDAAQPDAS RTGETHTVEW QAPAVAITRT 180
  181 ATQARQSNSV DLDKARLVVS VGRGIGSKEN IALAEQLCKA IGAELACSRP VAENEKWMEH 240
  241 ERYVGISNLM LKPELYLAVG ISGQIQHMVG ANASQTIFAI NKDKNAPIFQ YADYGIVGDA 300
  301 VKILPALTAA LAR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	83.39794
Match:	1t9gR
Description:	Structure of the human MCAD:ETF complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
protein deacetylase activity	1.51448914762027	bayes_pls_golite062009
histone deacetylase activity	1.46996164044558	bayes_pls_golite062009
NAD-dependent histone deacetylase activity	1.36339794415677	bayes_pls_golite062009
NAD-dependent protein deacetylase activity	1.36339794415677	bayes_pls_golite062009
binding	1.19942441653074	bayes_pls_golite062009
deacetylase activity	0.719738423784827	bayes_pls_golite062009
protein binding	0.498410485514887	bayes_pls_golite062009
transcription factor binding	0.32988135787739	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: