YRC Public Data Repository - Protein Structure Prediction

Protein:	FECR_ECOLI
Organism:	Escherichia coli
Length:	317 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FECR_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|30180040, gi\|... - gi\|30248155\|ref\|NP_840225.1\| putative transmembrane sensor [Nitrosomonas europaea ATCC 19718], gi\|30...	277.0	[0..2]	[316..25]
gi\|191167128, gi... - gi\|75229681\|ref\|ZP_00716214.1\| COG3712: Fe2+-dicitrate sensor, membrane component [Escherichia coli ...	271.0	[0..1]	[317..1]
gi\|157156411, gi... - gi\|75189002\|ref\|ZP_00702269.1\| COG3712: Fe2+-dicitrate sensor, membrane component [Escherichia coli ...	271.0	[0..1]	[317..1]
gi\|70728365, gi\|... - gi\|70728365\|ref\|YP_258114.1\| sigma factor regulatory protein FecR/PupR family [Pseudomonas fluoresce...	270.0	[0..1]	[314..1]
gi\|74314757, gi\|... - gi\|74314757\|ref\|YP_313176.1\| fec operon regulator FecR [Shigella sonnei Ss046], gi\|73858234\|gb\|AAZ90... gi\|218372984, gi... - gi\|218702998\|ref\|YP_002410627.1\| fec operon regulator FecR [Escherichia coli IAI39], gi\|218372984\|em...	269.0	[0..1]	[317..1]
gi\|36784166, gi\|... - gi\|37524741\|ref\|NP_928085.1\| hypothetical protein plu0740 [Photorhabdus luminescens subsp. laumondii...	267.0	[0..10]	[315..26]

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Predicted Domain #1

Region A:
Residues: [1-317]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNPLLTDSRR QALRSASHWY AVLSGERVSP QQEARWQQWY EQDQDNQWAW QQVENLRNQL  60
   61 GGVPGDVASR ALHDTRLTRR HVMKGLLLLL GAGGGWQLWQ SETGEGLRAD YRTAKGTVSR 120
  121 QQLEDGSLLT LNTQSAADVR FDAHQRTVRL WYGEIAITTA KDALQRPFRV LTRQGQLTAL 180
  181 GTEFTVRQQD NFTQLDVQQH AVEVLLASAP AQKRIVNAGE SLQFSASEFG AVKPLDDEST 240
  241 SWTKDILSFS DKPLGEVIAT LTRYRNGVLR CDPAVAGLRL SGTFPLKNTD AILNVIAQTL 300
  301 PVKIQSITRY WINISPL

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	0.992
Match:	1mpxA
Description:	Alpha-amino acid ester hydrolase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.947074796716417	bayes_pls_golite062009
DNA binding	0.313421381360078	bayes_pls_golite062009
catalytic activity	0.301965453461894	bayes_pls_golite062009
nucleic acid binding	0.235988017293228	bayes_pls_golite062009
protein binding	0.102037008381724	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: