YRC Public Data Repository - Protein Structure Prediction

Protein:	FDNI_ECOLI
Organism:	Escherichia coli
Length:	217 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FDNI_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|62127772, gi\|... - gi\|62180139\|ref\|YP_216556.1\| formate dehydrogenase-N subunit gamma [Salmonella enterica subsp. enter...	185.0	[0..1]	[217..1]
gi\|56127742, gi\|... - gi\|56413485\|ref\|YP_150560.1\| formate dehydrogenase-N subunit gamma [Salmonella enterica subsp. enter...	184.0	[0..1]	[217..1]
gi\|168235674, gi... - gi\|197290955\|gb\|EDY30308.1\| formate dehydrogenase, gamma subunit [Salmonella enterica subsp. enteric... lcl\|NC_016856.1_... - [gene=fdnI] [protein=formate dehydrogenase-N subunit gamma] [protein_id=YP_005237459.1] [location=co... gi\|194738048, gi... - gi\|194738048\|ref\|YP_002114593.1\| formate dehydrogenase, gamma subunit [Salmonella enterica subsp. en... gi\|167549969, gi... - gi\|205324904\|gb\|EDZ12743.1\| formate dehydrogenase, gamma subunit [Salmonella enterica subsp. enteric... gi\|167992920, gi... - gi\|205328927\|gb\|EDZ15691.1\| formate dehydrogenase, gamma subunit [Salmonella enterica subsp. enteric... gi\|161613991, gi... - gi\|161613991\|ref\|YP_001587956.1\| formate dehydrogenase-N subunit gamma [Salmonella enterica subsp. e... gi\|207856937, gi... - gi\|207856937\|ref\|YP_002243588.1\| formate dehydrogenase-N subunit gamma [Salmonella enterica subsp. e... gi\|16420090, gi\|... - gi\|16764912\|ref\|NP_460527.1\| formate dehydrogenase-N subunit gamma [Salmonella typhimurium LT2], gi\|... gi\|197939983, gi... - gi\|198245467\|ref\|YP_002215578.1\| formate dehydrogenase, gamma subunit [Salmonella enterica subsp. en... gi\|199603443, gi... - gi\|200390998\|ref\|ZP_03217609.1\| formate dehydrogenase, gamma subunit [Salmonella enterica subsp. ent...	184.0	[0..1]	[217..1]
gi\|77973731 - gi\|77973731\|ref\|ZP_00829276.1\| COG2864: Cytochrome b subunit of formate dehydrogenase [Yersinia fred...	179.0	[0..1]	[215..1]
gi\|77978105 - gi\|77978105\|ref\|ZP_00833539.1\| COG2864: Cytochrome b subunit of formate dehydrogenase [Yersinia inte...	179.0	[0..1]	[215..1]
gi\|77960720 - gi\|77960720\|ref\|ZP_00824579.1\| COG2864: Cytochrome b subunit of formate dehydrogenase [Yersinia moll...	178.0	[0..1]	[215..1]
gi\|12720656, gi\|... - gi\|15602271\|ref\|NP_245343.1\| FdxI [Pasteurella multocida subsp. multocida str. Pm70], gi\|12720656\|gb...	176.0	[0..1]	[213..6]
gi\|26247764, gi\|... - gi\|26247764\|ref\|NP_753804.1\| formate dehydrogenase-N subunit gamma [Escherichia coli CFT073], gi\|261... gi\|227886132, gi... - gi\|227886132\|ref\|ZP_04003937.1\| formate dehydrogenase-N subunit gamma [Escherichia coli 83972], gi\|2... gi\|218704948, gi... - gi\|218704948\|ref\|YP_002412467.1\| formate dehydrogenase-N subunit gamma [Escherichia coli UMN026], gi... gi\|218426960, gi... - gi\|218689396\|ref\|YP_002397608.1\| formate dehydrogenase-N subunit gamma [Escherichia coli ED1a], gi\|2...	174.0	[0..1]	[217..1]
gi\|82544073, gi\|... - gi\|82544073\|ref\|YP_408020.1\| formate dehydrogenase-N subunit gamma [Shigella boydii Sb227], gi\|81245...	173.0	[0..1]	[217..1]
gi\|237705453, gi... - gi\|237705453\|ref\|ZP_04535934.1\| formate dehydrogenase-N subunit gamma [Escherichia sp. 3_2_53FAA], g... gi\|115512836, gi... - gi\|117623712\|ref\|YP_852625.1\| formate dehydrogenase-N subunit gamma [Escherichia coli APEC O1], gi\|1...	173.0	[0..1]	[217..7]

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Predicted Domain #1

Region A:
Residues: [1-217]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKSKMIVRT KFIDRACHWT VVICFFLVAL SGISFFFPTL QWLTQTFGTP QMGRILHPFF  60
   61 GIAIFVALMF MFVRFVHHNI PDKKDIPWLL NIVEVLKGNE HKVADVGKYN AGQKMMFWSI 120
  121 MSMIFVLLVT GVIIWRPYFA QYFPMQVVRY SLLIHAAAGI ILIHAILIHM YMAFWVKGSI 180
  181 KGMIEGKVSR RWAKKHHPRW YREIEKAEAK KESEEGI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	43.522879
Match:	1kqfC
Description:	Formate dehydrogenase N, cytochrome (gamma) subunit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
formate dehydrogenase activity	12.0031413212101	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	6.74953039117709	bayes_pls_golite062009
oxidoreductase activity	6.50321219171766	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	6.34988495153085	bayes_pls_golite062009
ubiquinol-cytochrome-c reductase activity	4.50524595323325	bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor	4.50524595323325	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	4.29455986972274	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	4.14658254808421	bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors	4.11558350750273	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	3.50341532760587	bayes_pls_golite062009
electron carrier activity	3.28715047874253	bayes_pls_golite062009
cation transmembrane transporter activity	3.24971217721974	bayes_pls_golite062009
ion transmembrane transporter activity	3.0416933490072	bayes_pls_golite062009
catalytic activity	1.19342057724506	bayes_pls_golite062009
binding	1.00930558921984	bayes_pls_golite062009
protein binding	0.588939203772891	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.173080554590997	bayes_pls_golite062009
substrate-specific transporter activity	0.0890676728517352	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: