YRC Public Data Repository - Protein Structure Prediction

Protein:	FDHE_ECOLI
Organism:	Escherichia coli
Length:	309 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FDHE_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|124501254, gi... - gi\|124527552\|ref\|ZP_01699017.1\| formate dehydrogenase accessory protein FdhE [Escherichia coli B], g... FDHE_ECOLC - Protein FdhE OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=fdhE PE=3 SV=1 FDHE_ECOHS - Protein FdhE OS=Escherichia coli O9:H4 (strain HS) GN=fdhE PE=3 SV=1 gi\|83586262, gi\|... - gi\|83586262\|ref\|ZP_00924898.1\| COG3058: Uncharacterized protein involved in formate dehydrogenase fo... gi\|251787155, gi... - gi\|251787155\|ref\|YP_003001459.1\| hypothetical protein B21_03725 [Escherichia coli BL21], gi\|24237942... gi\|226838538, gi... - gi\|254039102\|ref\|ZP_04873152.1\| fdhE [Escherichia sp. 1_1_43], gi\|226838538\|gb\|EEH70567.1\| fdhE [Esc... gi\|253775471, gi... - gi\|254290592\|ref\|YP_003056340.1\| formate dehydrogenase accessory protein FdhE [Escherichia coli BL21... gi\|253975742, gi... - gi\|254163841\|ref\|YP_003046949.1\| formate dehydrogenase accessory protein FdhE [Escherichia coli B st...	462.0	[0..1]	[309..1]
gi\|75513962, gi\|... - gi\|75513962\|ref\|ZP_00736315.1\| COG3058: Uncharacterized protein involved in formate dehydrogenase fo...	461.0	[0..1]	[309..1]
gi\|25355251, gi\|... - pir\|\|H86077 affects formate dehydrogenase-N [imported] - Escherichia coli (strain O157:H7, substrain... gi\|12518783, gi\|... - gi\|15804480\|ref\|NP_290520.1\| formate dehydrogenase accessory protein FdhE [Escherichia coli O157:H7 ... FDHE_SHIDS - Protein FdhE OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=fdhE PE=3 SV=1 FDHE_ECOSE - Protein FdhE OS=Escherichia coli (strain SE11) GN=fdhE PE=3 SV=1 FDHE_ECO5E - Protein FdhE OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=fdhE PE=3 SV=1 gi\|193063999, gi... - gi\|75258126\|ref\|ZP_00729587.1\| COG3058: Uncharacterized protein involved in formate dehydrogenase fo... FDHE_ESCF3 - Protein FdhE OS=Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73) GN=fdhE PE=3 SV... FDHE_SHISS - Protein FdhE OS=Shigella sonnei (strain Ss046) GN=fdhE PE=3 SV=1 gi\|217321413, gi... - gi\|217325192\|ref\|ZP_03441276.1\| formate dehydrogenase accessory protein FdhE [Escherichia coli O157:... FDHE_ECO55 - Protein FdhE OS=Escherichia coli (strain 55989 / EAEC) GN=fdhE PE=3 SV=1 FDHE_ECO8A - Protein FdhE OS=Escherichia coli O8 (strain IAI1) GN=fdhE PE=3 SV=1 gi\|194433284, gi... - gi\|83569845\|ref\|ZP_00921294.1\| COG3058: Uncharacterized protein involved in formate dehydrogenase fo... gi\|190903493, gi... - gi\|75230412\|ref\|ZP_00716898.1\| COG3058: Uncharacterized protein involved in formate dehydrogenase fo... gi\|193068099, gi... - gi\|75238334\|ref\|ZP_00722333.1\| COG3058: Uncharacterized protein involved in formate dehydrogenase fo... FDHE_ECO24 - Protein FdhE OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=fdhE PE=3 SV=1 gi\|75211295, gi\|... - gi\|75211295\|ref\|ZP_00711394.1\| COG3058: Uncharacterized protein involved in formate dehydrogenase fo... gi\|168780802, gi... - gi\|189001537\|gb\|EDU70523.1\| formate dehydrogenase accessory protein FdhE [Escherichia coli O157:H7 s... gi\|187769223, gi... - gi\|187769223\|gb\|EDU33067.1\| formate dehydrogenase accessory protein FdhE [Escherichia coli O157:H7 s... gi\|189378017, gi... - gi\|189378017\|gb\|EDU96433.1\| formate dehydrogenase accessory protein FdhE [Escherichia coli O157:H7 s... gi\|189373364, gi... - gi\|189373364\|gb\|EDU91780.1\| formate dehydrogenase accessory protein FdhE [Escherichia coli O157:H7 s... gi\|208728464, gi... - gi\|208808663\|ref\|ZP_03251000.1\| formate dehydrogenase accessory protein FdhE [Escherichia coli O157:... gi\|195937531 - gi\|195937531\|ref\|ZP_03082913.1\| formate dehydrogenase accessory protein FdhE [Escherichia coli O157:... gi\|208819914, gi... - gi\|208819914\|ref\|ZP_03260234.1\| formate dehydrogenase accessory protein FdhE [Escherichia coli O157:... FDHE_ECO57 - Protein FdhE OS=Escherichia coli O157:H7 GN=fdhE PE=3 SV=1 gi\|15834071, gi\|... - gi\|15834071\|ref\|NP_312844.1\| formate dehydrogenase accessory protein FdhE [Escherichia coli O157:H7 ... gi\|208813794, gi... - gi\|208813794\|ref\|ZP_03255123.1\| formate dehydrogenase accessory protein FdhE [Escherichia coli O157:... gi\|168755569, gi... - gi\|189357182\|gb\|EDU75601.1\| formate dehydrogenase accessory protein FdhE [Escherichia coli O157:H7 s... gi\|188016764, gi... - gi\|188016764\|gb\|EDU54886.1\| formate dehydrogenase accessory protein FdhE [Escherichia coli O157:H7 s... gi\|168768186, gi... - gi\|189362736\|gb\|EDU81155.1\| formate dehydrogenase accessory protein FdhE [Escherichia coli O157:H7 s... gi\|168761732, gi... - gi\|189367932\|gb\|EDU86348.1\| formate dehydrogenase accessory protein FdhE [Escherichia coli O157:H7 s... gi\|254595286, gi... - gi\|254795886\|ref\|YP_003080723.1\| formate dehydrogenase formation protein [Escherichia coli O157:H7 s...	460.0	[0..1]	[309..1]
FDHE_SHIFL - Protein FdhE homolog OS=Shigella flexneri GN=fdhE PE=3 SV=1 FDHE_SHIF8 - Protein FdhE OS=Shigella flexneri serotype 5b (strain 8401) GN=fdhE PE=3 SV=1 gi\|24054466, gi\|... - gi\|24115185\|ref\|NP_709695.1\| formate dehydrogenase accessory protein FdhE [Shigella flexneri 2a str.... gi\|30043076, gi\|... - gi\|30064816\|ref\|NP_838987.1\| formate dehydrogenase accessory protein FdhE [Shigella flexneri 2a str....	460.0	[0..1]	[309..1]
FDHE_ECO7I - Protein FdhE OS=Escherichia coli O7:K1 (strain IAI39 / ExPEC) GN=fdhE PE=3 SV=1 gi\|226902860, gi... - gi\|237702923\|ref\|ZP_04533404.1\| fdhE [Escherichia sp. 3_2_53FAA], gi\|226902860\|gb\|EEH89119.1\| fdhE [... FDHE_ECOLU - Protein FdhE OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) GN=fdhE PE=3 SV=1 gi\|227885369, gi... - gi\|227885369\|ref\|ZP_04003174.1\| formate dehydrogenase accessory protein FdhE [Escherichia coli 83972... FDHE_ECOL5 - Protein FdhE OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=fdhE PE=3 SV=1 FDHE_ECOUT - Protein FdhE OS=Escherichia coli (strain UTI89 / UPEC) GN=fdhE PE=3 SV=1 FDHE_ECOL6 - Protein FdhE OS=Escherichia coli O6 GN=fdhE PE=3 SV=1 FDHE_ECOK1 - Protein FdhE OS=Escherichia coli O1:K1 / APEC GN=fdhE PE=3 SV=1 FDHE_ECOL6 - Protein FdhE OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=fdhE PE=3 SV=1 gi\|75237854, gi\|... - gi\|75237854\|ref\|ZP_00721869.1\| COG3058: Uncharacterized protein involved in formate dehydrogenase fo... FDHE_ECO45 - Protein FdhE OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=fdhE PE=3 SV=1 FDHE_ECO81 - Protein FdhE OS=Escherichia coli O81 (strain ED1a) GN=fdhE PE=3 SV=1	459.0	[0..1]	[309..1]
FDHE_SHIB3 - Protein FdhE OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=fdhE PE=3 SV=1 FDHE_SHIBS - Protein FdhE OS=Shigella boydii serotype 4 (strain Sb227) GN=fdhE PE=3 SV=1	458.0	[0..1]	[309..1]
gi\|214002292 - gi\|214002292\|ref\|ZP_03413027.1\| formate dehydrogenase accessory protein FdhE [Salmonella enterica su... gi\|213647350 - gi\|213647350\|ref\|ZP_03377403.1\| formate dehydrogenase accessory protein FdhE [Salmonella enterica su... FDHE_SALTI - Protein FdhE OS=Salmonella typhi GN=fdhE PE=3 SV=1 gi\|29143887, gi\|... - gi\|29143887\|ref\|NP_807229.1\| formate dehydrogenase accessory protein FdhE [Salmonella enterica subsp... gi\|16762399 - gi\|16762399\|ref\|NP_458016.1\| formate dehydrogenase accessory protein FdhE [Salmonella enterica subsp... FDHE_SALTI - Protein fdhE OS=Salmonella typhi GN=fdhE PE=3 SV=1	452.0	[0..1]	[309..1]
FDHE_SALPB - Protein FdhE OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=fdhE PE=3 SV=1 FDHE_SALTY - Protein fdhE OS=Salmonella typhimurium GN=fdhE PE=3 SV=1 gi\|238912178 - gi\|238912178\|ref\|ZP_04656015.1\| formate dehydrogenase accessory protein FdhE [Salmonella enterica su... gi\|197242590, gi... - gi\|197264335\|ref\|ZP_03164409.1\| formate dehydrogenase accessory protein FdhE [Salmonella enterica su... FDHE_SALA4 - Protein FdhE OS=Salmonella agona (strain SL483) GN=fdhE PE=3 SV=1 FDHE_SALPB - Protein fdhE OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=fdhE PE=3 SV=1 FDHE_SALSV - Protein FdhE OS=Salmonella schwarzengrund (strain CVM19633) GN=fdhE PE=3 SV=1 gi\|194458719, gi... - gi\|194472355\|ref\|ZP_03078339.1\| formate dehydrogenase accessory protein FdhE [Salmonella enterica su... FDHE_SALTY - Protein FdhE OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=fdhE PE=3 SV=1 FDHE_SALPC - Protein FdhE OS=Salmonella paratyphi C (strain RKS4594) GN=fdhE PE=3 SV=1 gi\|204320624, gi... - gi\|204930220\|ref\|ZP_03221197.1\| formate dehydrogenase accessory protein FdhE [Salmonella enterica su... gi\|197289337, gi... - gi\|197289337\|gb\|EDY28702.1\| formate dehydrogenase accessory protein FdhE [Salmonella enterica subsp.... gi\|205332862, gi... - gi\|205332862\|gb\|EDZ19626.1\| formate dehydrogenase accessory protein FdhE [Salmonella enterica subsp.... gi\|167991559, gi... - gi\|205330085\|gb\|EDZ16849.1\| formate dehydrogenase accessory protein FdhE [Salmonella enterica subsp.... gi\|205323685, gi... - gi\|205323685\|gb\|EDZ11524.1\| formate dehydrogenase accessory protein FdhE [Salmonella enterica subsp.... FDHE_SALTY - Protein FdhE OS=Salmonella typhimurium GN=fdhE PE=3 SV=1 lcl\|NC_016856.1_... - [gene=fdhE] [protein=formate dehydrogenase accessory protein FdhE] [protein_id=YP_005240302.1] [loca... FDHE_SALHS - Protein FdhE OS=Salmonella heidelberg (strain SL476) GN=fdhE PE=3 SV=1 FDHE_SALNS - Protein FdhE OS=Salmonella newport (strain SL254) GN=fdhE PE=3 SV=1 gi\|205341779, gi... - gi\|205341779\|gb\|EDZ28543.1\| formate dehydrogenase accessory protein FdhE [Salmonella enterica subsp.... gi\|205336844, gi... - gi\|205336844\|gb\|EDZ23608.1\| formate dehydrogenase accessory protein FdhE [Salmonella enterica subsp....	451.0	[0..1]	[309..1]
FDHE_SALPA - Protein FdhE OS=Salmonella paratyphi A GN=fdhE PE=3 SV=1 FDHE_SALPK - Protein FdhE OS=Salmonella paratyphi A (strain AKU_12601) GN=fdhE PE=3 SV=1 FDHE_SALPA - Protein FdhE OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=fdhE PE=3 SV=1	449.0	[0..1]	[309..1]
FDHE_SALCH - Protein fdhE OS=Salmonella choleraesuis GN=fdhE PE=3 SV=1 FDHE_SALCH - Protein FdhE OS=Salmonella choleraesuis GN=fdhE PE=3 SV=1 FDHE_SALCH - Protein FdhE OS=Salmonella choleraesuis (strain SC-B67) GN=fdhE PE=3 SV=1	449.0	[0..1]	[309..1]

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Predicted Domain #1

Region A:
Residues: [1-309]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIRIIPQDE LGSSEKRTAD MIPPLLFPRL KNLYNRRAER LRELAENNPL GDYLRFAALI  60
   61 AHAQEVVLYD HPLEMDLTAR IKEASAQGKP PLDIHVLPRD KHWQKLLMAL IAELKPEMSG 120
  121 PALAVIENLE KASTQELEDM ASALFASDFS SVSSDKAPFI WAALSLYWAQ MANLIPGKAR 180
  181 AEYGEQRQYC PVCGSMPVSS MVQIGTTQGL RYLHCNLCET EWHVVRVKCS NCEQSGKLHY 240
  241 WSLDDEQAAI KAESCDDCDT YLKILYQEKD PKIEAVADDL ASLVLDARME QEGYARSSIN 300
  301 PFLFPGEGE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	80.30103
Match:	2fiyA
Description:	The crystal structure of the FdhE protein from Pseudomonas aeruginosa
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.00549246699747	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: