YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: EX9_ECOLI
Organism: Escherichia coli
Length: 281 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EX9_ECOLI.

Description E-value Query
Range
Subject
Range
gi|39982411, gi|... - gi|39995648|ref|NP_951599.1| DNA polymerase I [Geobacter sulfurreducens PCA], gi|39982411|gb|AAR3387...
298.0 [0..30] [279..1]
gi|77951812, gi|... - gi|77951812|ref|ZP_00816231.1| DNA polymerase A [Marinobacter aquaeolei VT8], gi|77869419|gb|EAP0068...
298.0 [0..15] [281..46]
gi|114322007, gi... - gi|78702619|ref|ZP_00867050.1| DNA polymerase A [Alkalilimnicola ehrlichei MLHE-1], gi|78519889|gb|E...
295.0 [0..32] [278..5]
gi|78484390, gi|... - gi|78484390|ref|YP_390315.1| DNA polymerase I [Thiomicrospira crunogena XCL-2], gi|78362676|gb|ABB40...
293.0 [0..30] [278..9]
gi|88937762, gi|... - gi|88937762|ref|ZP_01143307.1| DNA polymerase A [Geobacter uraniumreducens Rf4], gi|88915498|gb|EAR3...
292.0 [0..32] [278..5]
gi|52627465, gi|... - gi|52840354|ref|YP_094153.1| DNA polymerase I [Legionella pneumophila subsp. pneumophila str. Philad...
290.0 [0..31] [277..1]
gi|53749879, gi|... - gi|54296094|ref|YP_122463.1| DNA polymerase I [Legionella pneumophila str. Paris], gi|53749879|emb|C...
290.0 [0..31] [277..1]
gi|54293062, gi|... - gi|54293062|ref|YP_125477.1| DNA polymerase I [Legionella pneumophila str. Lens], gi|53752894|emb|CA...
289.0 [0..31] [277..1]
DPO1_BACCA - DNA polymerase I OS=Bacillus caldotenax GN=polA PE=1 SV=1
289.0 [0..31] [280..1]
gi|78195431, gi|... - gi|78224176|ref|YP_385923.1| DNA polymerase I [Geobacter metallireducens GS-15], gi|78195431|gb|ABB3...
289.0 [0..32] [270..4]

Back

Predicted Domain #1
Region A:
Residues: [1-281]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRGLFPISHP AVACSGIECY PYRLIFKGVI VAVHLLIVDA LNLIRRIHAV QGSPCVETCQ  60
   61 HALDQLIMHS QPTHAVAVFD DENRSSGWRH QRLPDYKAGR PPMPEELHDE MPALRAAFEQ 120
  121 RGVPCWSTSG NEADDLAATL AVKVTQAGHQ ATIVSTDKGY CQLLSPTLRI RDYFQKRWLD 180
  181 APFIDKEFGV QPQQLPDYWG LAGISSSKVP GVAGIGPKSA TQLLVEFQSL EGIYENLDAV 240
  241 AEKWRKKLET HKEMAFLCRD IARLQTDLHI DGNLQQLRLV R

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 66.69897
Match: 1bgxT
Description: 5' to 3' exonuclease domain of DNA polymerase Taq; Exonuclease domain of prokaryotic DNA polymerase; DNA polymerase I (Klenow fragment)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
deoxyribonuclease activity 2.76214864778674 bayes_pls_golite062009
endonuclease activity 2.56010795198277 bayes_pls_golite062009
flap endonuclease activity 2.53758571886688 bayes_pls_golite062009
endodeoxyribonuclease activity 2.52591027275626 bayes_pls_golite062009
exonuclease activity 2.5100646091515 bayes_pls_golite062009
hydrolase activity 2.33175366185717 bayes_pls_golite062009
5'-3' exonuclease activity 2.29772244408635 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 2.13887861178898 bayes_pls_golite062009
catalytic activity 1.74578892363435 bayes_pls_golite062009
exodeoxyribonuclease activity 1.70427268530827 bayes_pls_golite062009
exodeoxyribonuclease activity, producing 5'-phosphomonoesters 1.70203514795969 bayes_pls_golite062009
nuclease activity 1.66579180796794 bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1.34815460610781 bayes_pls_golite062009
5'-3' exodeoxyribonuclease activity 0.99824405209499 bayes_pls_golite062009
single-stranded DNA specific exodeoxyribonuclease activity 0.93326471256937 bayes_pls_golite062009
double-stranded DNA specific exodeoxyribonuclease activity 0.75324098318674 bayes_pls_golite062009
5'-flap endonuclease activity 0.59155477779901 bayes_pls_golite062009
endodeoxyribonuclease activity, producing 5'-phosphomonoesters 0.44366322002827 bayes_pls_golite062009
binding 0.135870115528543 bayes_pls_golite062009
single-stranded DNA specific 5'-3' exodeoxyribonuclease activity 0.0390389256036001 bayes_pls_golite062009
DNA binding 0.0110216579283602 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle