YRC Public Data Repository - Protein Structure Prediction

Protein:	ENVY_ECOLI
Organism:	Escherichia coli
Length:	253 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ENVY_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|68233379, gi\|... - gi\|68233379\|ref\|ZP_00572501.1\| Helix-turn-helix, AraC type:ThiJ/PfpI [Frankia sp. EAN1pec], gi\|68198...	167.0	[0..34]	[249..122]
gi\|187769903, gi... - gi\|187769903\|gb\|EDU33747.1\| transcriptional regulator AdiY [Escherichia coli O157:H7 str. EC4196], g... gi\|189363998, gi... - gi\|189363998\|gb\|EDU82417.1\| transcriptional regulator AdiY [Escherichia coli O157:H7 str. EC4486], g... gi\|168784744, gi... - gi\|189375119\|gb\|EDU93535.1\| transcriptional regulator AdiY [Escherichia coli O157:H7 str. EC869], gi... gi\|168780539, gi... - gi\|189001684\|gb\|EDU70670.1\| transcriptional regulator AdiY [Escherichia coli O157:H7 str. EC4076], g... gi\|117626403, gi... - gi\|117626403\|ref\|YP_859726.1\| putative regulatory protein AdiY [Escherichia coli APEC O1], gi\|115515... gi\|168748028, gi... - gi\|188017557\|gb\|EDU55679.1\| transcriptional regulator AdiY [Escherichia coli O157:H7 str. EC4113], g... gi\|189368509, gi... - gi\|189368509\|gb\|EDU86925.1\| transcriptional regulator AdiY [Escherichia coli O157:H7 str. EC4501], g... gi\|124501199, gi... - gi\|124527756\|ref\|ZP_01699191.1\| transcriptional regulator, AraC family [Escherichia coli B], gi\|1245... gi\|189357489, gi... - gi\|189357489\|gb\|EDU75908.1\| transcriptional regulator AdiY [Escherichia coli O157:H7 str. EC4401], g... gi\|215267538, gi... - gi\|215489466\|ref\|YP_002331897.1\| DNA-binding transcriptional activator [Escherichia coli O127:H6 str... gi\|209914864, gi... - gi\|209921605\|ref\|YP_002295689.1\| putative transcriptional regulator [Escherichia coli SE11], gi\|2099... gi\|218363437, gi... - gi\|218556668\|ref\|YP_002389582.1\| DNA-binding transcriptional activator [Escherichia coli IAI1], gi\|2... gi\|217324139, gi... - gi\|217324139\|ref\|ZP_03440223.1\| transcriptional regulator AdiY [Escherichia coli O157:H7 str. TW1458... gi\|208812029, gi... - gi\|208812029\|ref\|ZP_03253358.1\| transcriptional regulator AdiY [Escherichia coli O157:H7 str. EC4045... gi\|208809024, gi... - gi\|208809024\|ref\|ZP_03251361.1\| transcriptional regulator AdiY [Escherichia coli O157:H7 str. EC4206... gi\|209157970, gi... - gi\|209396570\|ref\|YP_002273660.1\| transcriptional regulator AdiY [Escherichia coli O157:H7 str. EC411... gi\|208741309, gi... - gi\|208821186\|ref\|ZP_03261506.1\| transcriptional regulator AdiY [Escherichia coli O157:H7 str. EC4042... gi\|193063081, gi... - gi\|193063081\|ref\|ZP_03044173.1\| transcriptional regulator AdiY [Escherichia coli E22], gi\|192931340\|... gi\|191173354, gi... - gi\|191173354\|ref\|ZP_03034883.1\| transcriptional regulator AdiY [Escherichia coli F11], gi\|190906330\|... gi\|195935905 - gi\|195935905\|ref\|ZP_03081287.1\| AraC family transcriptional regulator [Escherichia coli O157:H7 str.... gi\|194415150, gi... - gi\|194426814\|ref\|ZP_03059367.1\| transcriptional regulator AdiY [Escherichia coli B171], gi\|194415150... gi\|170021886, gi... - gi\|170021886\|ref\|YP_001726840.1\| AraC family transcriptional regulator [Escherichia coli ATCC 8739],... gi\|168798212, gi... - gi\|189379142\|gb\|EDU97558.1\| transcriptional regulator AdiY [Escherichia coli O157:H7 str. EC508], gi... gi\|187429775, gi... - gi\|187732783\|ref\|YP_001882783.1\| transcriptional regulator AdiY [Shigella boydii CDC 3083-94], gi\|18... gi\|170681441, gi... - gi\|170681441\|ref\|YP_001746509.1\| transcriptional regulator AdiY [Escherichia coli SMS-3-5], gi\|17051... gi\|24054615, gi\|... - gi\|24115315\|ref\|NP_709825.1\| putative ARAC-type regulatory protein [Shigella flexneri 2a str. 301], ... gi\|25326009, gi\|... - pir\|\|G86106 probable ARAC-type regulatory protein adiY [imported] - Escherichia coli (strain O157:H7... gi\|30064685, gi\|... - gi\|30064685\|ref\|NP_838856.1\| putative ARAC-type regulatory protein [Shigella flexneri 2a str. 2457T]... gi\|26250931, gi\|... - gi\|26250931\|ref\|NP_756971.1\| putative regulatory protein adiY [Escherichia coli CFT073], gi\|26111363... gi\|12519089, gi\|... - gi\|15804708\|ref\|NP_290749.1\| putative ARAC-type regulatory protein [Escherichia coli O157:H7 EDL933]... gi\|218429976, gi... - gi\|218692412\|ref\|YP_002400624.1\| DNA-binding transcriptional activator [Escherichia coli ED1a], gi\|2... gi\|15834352, gi\|... - gi\|15834352\|ref\|NP_313125.1\| putative ARAC-type regulatory protein [Escherichia coli O157:H7], gi\|13... gi\|218367974, gi... - gi\|218561205\|ref\|YP_002394118.1\| DNA-binding transcriptional activator [Escherichia coli S88], gi\|21... gi\|218707731, gi... - gi\|218707731\|ref\|YP_002415250.1\| DNA-binding transcriptional activator [Escherichia coli UMN026], gi... gi\|218354550, gi... - gi\|218697818\|ref\|YP_002405485.1\| DNA-binding transcriptional activator [Escherichia coli 55989], gi\|... gi\|91213663, gi\|... - gi\|91213663\|ref\|YP_543649.1\| AdiY transcriptional regulatory protein [Escherichia coli UTI89], gi\|91... gi\|15834352, gi\|... - gi\|15834352\|ref\|NP_313125.1\| putative ARAC-type regulatory protein [Escherichia coli O157:H7 str. Sa... gi\|82779153, gi\|... - gi\|82779153\|ref\|YP_405502.1\| putative ARAC-type regulatory protein [Shigella dysenteriae Sd197], gi\|... gi\|110644474, gi... - gi\|110644474\|ref\|YP_672204.1\| putative regulatory protein AdiY [Escherichia coli 536], gi\|110346066\|... gi\|82546451, gi\|... - gi\|82546451\|ref\|YP_410398.1\| putative ARAC-type regulatory protein [Shigella boydii Sb227], gi\|81247... gi\|110617433, gi... - gi\|110807885\|ref\|YP_691405.1\| putative ARAC-type regulatory protein [Shigella flexneri 5 str. 8401],... gi\|227836188, gi... - gi\|227886846\|ref\|ZP_04004651.1\| AraC family transcriptional regulator [Escherichia coli 83972], gi\|2... gi\|237703704, gi... - gi\|237703704\|ref\|ZP_04534185.1\| transcriptional regulator AdiY [Escherichia sp. 3_2_53FAA], gi\|22690... gi\|157069261, gi... - gi\|157163581\|ref\|YP_001460899.1\| transcriptional regulator AdiY [Escherichia coli HS], gi\|157069261\|... gi\|157155453, gi... - gi\|157155453\|ref\|YP_001465615.1\| transcriptional regulator AdiY [Escherichia coli E24377A], gi\|15707... gi\|254595538, gi... - gi\|254796138\|ref\|YP_003080975.1\| DNA-binding transcriptional activator [Escherichia coli O157:H7 str... gi\|74314601, gi\|... - gi\|74314601\|ref\|YP_313020.1\| putative ARAC-type regulatory protein [Shigella sonnei Ss046], gi\|73858...	163.0	[0..1]	[252..1]
gi\|254037126, gi... - gi\|254037126\|ref\|ZP_04871203.1\| adiY [Escherichia sp. 1_1_43], gi\|226840232\|gb\|EEH72234.1\| adiY [Esc... gi\|254290800, gi... - gi\|254290800\|ref\|YP_003056548.1\| DNA-binding transcriptional activator [Escherichia coli BL21(DE3)],... gi\|253975951, gi... - gi\|254164050\|ref\|YP_003047158.1\| DNA-binding transcriptional activator [Escherichia coli B str. REL6... EG11966 - adi system transcriptional activator / Transcriptional activator for adiA, AraC family gi\|194423829, gi... - gi\|194437273\|ref\|ZP_03069371.1\| transcriptional regulator AdiY [Escherichia coli 101-1], gi\|19442382... gi\|188489560, gi... - gi\|188494361\|ref\|ZP_03001631.1\| transcriptional regulator AdiY [Escherichia coli 53638], gi\|18848956... ADIY_ECOLI - HTH-type transcriptional regulator adiY - Escherichia coli EG11966 - adi system transcriptional activator / Transcriptional activator for adiA, AraC family gi\|242379643, gi... - gi\|251787370\|ref\|YP_003001674.1\| hypothetical protein B21_03948 [Escherichia coli BL21], gi\|24237964... gi\|89110837, gi\|... - gi\|89110837\|ref\|AP_004617.1\| DNA-binding transcriptional activator [Escherichia coli str. K-12 subst... gi\|238860883, gi... - gi\|238903224\|ref\|YP_002929020.1\| DNA-binding transcriptional activator [Escherichia coli BW2952], gi...	162.0	[0..1]	[252..1]
gi\|126237498, gi... - gi\|92906846\|ref\|ZP_01275626.1\| Helix-turn-helix, AraC type:ThiJ/PfpI [Mycobacterium sp. JLS], gi\|924...	162.0	[0..35]	[247..104]
gi\|83643766, gi\|... - gi\|83643766\|ref\|YP_432201.1\| transcriptional regulator [Hahella chejuensis KCTC 2396], gi\|83631809\|g...	162.0	[0..39]	[252..120]
gi\|110560831, gi... - gi\|114569282\|ref\|YP_755962.1\| transcriptional regulator [Maricaulis maris MCS10], gi\|114339744\|gb\|AB...	162.0	[0..34]	[250..129]
gi\|108772130, gi... - gi\|108801711\|ref\|YP_641908.1\| transcriptional regulator [Mycobacterium sp. MCS], gi\|108772130\|gb\|ABG... gi\|119696951, gi... - gi\|92914531\|ref\|ZP_01283158.1\| Helix-turn-helix, AraC type:ThiJ/PfpI [Mycobacterium sp. KMS], gi\|924...	162.0	[0..35]	[247..104]
gi\|85824568, gi\|... - gi\|86138921\|ref\|ZP_01057493.1\| transcriptional regulator, AraC family protein [Roseobacter sp. MED19...	161.0	[0..38]	[246..91]
gi\|16505284, gi\|... - gi\|25326011\|pir\|\|AG1022 probable AraC family regulatory protein STY4494 [imported] - Salmonella ente... gi\|213419526 - gi\|213419526\|ref\|ZP_03352592.1\| putative AraC family regulatory protein [Salmonella enterica subsp. ... gi\|29140102, gi\|... - gi\|29144464\|ref\|NP_807806.1\| AraC family regulatory protein [Salmonella enterica subsp. enterica ser... gi\|213427222 - gi\|213427222\|ref\|ZP_03359972.1\| putative AraC family regulatory protein [Salmonella enterica subsp. ... gi\|213585588 - gi\|213585588\|ref\|ZP_03367414.1\| putative AraC family regulatory protein [Salmonella enterica subsp. ... gi\|213609429 - gi\|213609429\|ref\|ZP_03369255.1\| putative AraC family regulatory protein [Salmonella enterica subsp. ... gi\|16762977 - gi\|16762977\|ref\|NP_458594.1\| AraC family regulatory protein [Salmonella enterica subsp. enterica ser... gi\|197365020, gi... - gi\|197365020\|ref\|YP_002144657.1\| putative AraC family regulatory protein [Salmonella enterica subsp.... gi\|213161960 - gi\|213161960\|ref\|ZP_03347670.1\| putative AraC family regulatory protein [Salmonella enterica subsp. ... gi\|214002531 - gi\|214002531\|ref\|ZP_03413266.1\| putative AraC family regulatory protein [Salmonella enterica subsp. ... gi\|56416094, gi\|... - gi\|56416094\|ref\|YP_153169.1\| AraC family regulatory protein [Salmonella enterica subsp. enterica ser...	160.0	[0..1]	[250..1]
gi\|16422856, gi\|... - gi\|16767545\|ref\|NP_463160.1\| transcriptional activator [Salmonella typhimurium LT2], gi\|16422856\|gb\|... lcl\|NC_016856.1_... - [gene=adiY] [protein=transcriptional activator] [protein_id=YP_005240602.1] [location=complement(455... gi\|206711252, gi... - gi\|207859449\|ref\|YP_002246100.1\| putative AraC family regulatory protein [Salmonella enterica subsp.... gi\|161366802, gi... - gi\|161617438\|ref\|YP_001591403.1\| hypothetical protein SPAB_05295 [Salmonella enterica subsp. enteric... gi\|205337301, gi... - gi\|205337301\|gb\|EDZ24065.1\| porin thermoregulatory protein EnvY [Salmonella enterica subsp. enterica...	160.0	[0..1]	[250..1]

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Predicted Domain #1

Region A:
Residues: [1-132]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQLSSSEPCV VILTEKEVEV SVNNHATFTL PKNYLAAFAC NNNVIELSTL NHVLITHINR  60
   61 NIINDYLLFL NKNLTCVKPW SRLATPVIAC HSRTPEVFRL AANHSKQQPS RPCEAELTRA 120
  121 LLFTVLSNFL EQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	3.522879
Match:	1xjaA
Description:	Apo form of the Y31V mutant dimerization domain fragment of Escherichia coli regulatory protein AraC
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [133-253]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SRFIALLMYI LRSSVRDSVC RIIQSDIQHY WNLRIVASSL CLSPSLLKKK LKNENTSYSQ  60
   61 IVTECRMRYA VQMLLMDNKN ITQVAQLCGY SSTSYFISVF KAFYGLTPLN YLAKQRQKVM 120
  121 W

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	19.39794
Match:	1bl0A
Description:	MarA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	3.57523737355937	bayes_pls_golite062009
DNA binding	2.7565055095762	bayes_pls_golite062009
nucleic acid binding	2.48097584527739	bayes_pls_golite062009
transcription factor activity	2.33198016659192	bayes_pls_golite062009
binding	2.21133851845856	bayes_pls_golite062009
sequence-specific DNA binding	0.37638337609693	bayes_pls_golite062009
RNA polymerase II transcription factor activity	0.24108783215685	bayes_pls_golite062009
transcription repressor activity	0.20862059645422	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: