YRC Public Data Repository - Protein Structure Prediction

Protein:	DCLZ_ECOLI
Organism:	Escherichia coli
Length:	713 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DCLZ_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|115515540, gi... - gi\|117626416\|ref\|YP_859739.1\| lysine decarboxylase 1 [Escherichia coli APEC O1], gi\|115515540\|gb\|ABJ... gi\|227886828, gi... - gi\|227886828\|ref\|ZP_04004633.1\| lysine decarboxylase 1 [Escherichia coli 83972], gi\|227836170\|gb\|EEJ...	610.0	[0..1]	[711..14]
gi\|237703722, gi... - gi\|237703722\|ref\|ZP_04534203.1\| lysine decarboxylase 1 [Escherichia sp. 3_2_53FAA], gi\|226901634\|gb\|... gi\|26111380, gi\|... - gi\|26250948\|ref\|NP_756988.1\| lysine decarboxylase, inducible [Escherichia coli CFT073], gi\|26111380\|... gi\|91075255, gi\|... - gi\|91213681\|ref\|YP_543667.1\| CadA, subunit of lysine decarboxylase [Escherichia coli UTI89], gi\|9107...	610.0	[0..1]	[711..3]
gi\|59712664, gi\|... - gi\|59712664\|ref\|YP_205440.1\| lysine decarboxylase 1 [Vibrio fischeri ES114], gi\|59480765\|gb\|AAW86552...	610.0	[0..1]	[711..1]
gi\|188017563, gi... - gi\|188017563\|gb\|EDU55685.1\| lysine decarboxylase, constitutive [Escherichia coli O157:H7 str. EC4113... gi\|124527770, gi... - gi\|124527770\|ref\|ZP_01699205.1\| Lysine decarboxylase [Escherichia coli B], gi\|124501213\|gb\|EAY48679.... EG10131 - lysine decarboxylase, acid-inducible / Lysine decarboxylase, inducible; decameric gi\|238861691, gi... - gi\|238903240\|ref\|YP_002929036.1\| lysine decarboxylase 1 [Escherichia coli BW2952], gi\|238861691\|gb\|A... gi\|253975965, gi... - gi\|254164064\|ref\|YP_003047172.1\| lysine decarboxylase 1 [Escherichia coli B str. REL606], gi\|2539759... gi\|254796154, gi... - gi\|254796154\|ref\|YP_003080991.1\| lysine decarboxylase 1 [Escherichia coli O157:H7 str. TW14359], gi\|... gi\|15834367, gi\|... - gi\|15834367\|ref\|NP_313140.1\| lysine decarboxylase 1 [Escherichia coli O157:H7 str. Sakai], gi\|133645... gi\|251787385, gi... - gi\|251787385\|ref\|YP_003001689.1\| hypothetical protein B21_03964 [Escherichia coli BL21], gi\|24237965... gi\|253775240, gi... - gi\|254290814\|ref\|YP_003056562.1\| lysine decarboxylase 1 [Escherichia coli BL21(DE3)], gi\|253980121\|g... gi\|194426906, gi... - gi\|194426906\|ref\|ZP_03059459.1\| lysine decarboxylase, constitutive [Escherichia coli B171], gi\|19441... gi\|194437197, gi... - gi\|194437197\|ref\|ZP_03069295.1\| lysine decarboxylase, constitutive [Escherichia coli 101-1], gi\|1944... gi\|195935921 - gi\|195935921\|ref\|ZP_03081303.1\| lysine decarboxylase 1 [Escherichia coli O157:H7 str. EC4024] gi\|208728582, gi... - gi\|208808781\|ref\|ZP_03251118.1\| lysine decarboxylase, constitutive [Escherichia coli O157:H7 str. EC... gi\|89110853, gi\|... - gi\|89110853\|ref\|AP_004633.1\| lysine decarboxylase 1 [Escherichia coli str. K-12 substr. W3110], gi\|8... gi\|170083581, gi... - gi\|170083581\|ref\|YP_001732901.1\| lysine decarboxylase 1 [Escherichia coli str. K-12 substr. DH10B], ... gi\|170681667, gi... - gi\|170681667\|ref\|YP_001746528.1\| lysine decarboxylase, constitutive [Escherichia coli SMS-3-5], gi\|1... gi\|191165610, gi... - gi\|191165610\|ref\|ZP_03027450.1\| lysine decarboxylase, constitutive [Escherichia coli B7A], gi\|190904... gi\|192931389, gi... - gi\|193063130\|ref\|ZP_03044222.1\| lysine decarboxylase, constitutive [Escherichia coli E22], gi\|192931... gi\|189001793, gi... - gi\|189001793\|gb\|EDU70779.1\| lysine decarboxylase, constitutive [Escherichia coli O157:H7 str. EC4076... gi\|189374794, gi... - gi\|189374794\|gb\|EDU93210.1\| lysine decarboxylase, constitutive [Escherichia coli O157:H7 str. EC869]... gi\|189379162, gi... - gi\|189379162\|gb\|EDU97578.1\| lysine decarboxylase, constitutive [Escherichia coli O157:H7 str. EC508]... gi\|157163597, gi... - gi\|157163597\|ref\|YP_001460915.1\| lysine decarboxylase, constitutive [Escherichia coli HS], gi\|157069... gi\|170021871, gi... - gi\|170021871\|ref\|YP_001726825.1\| lysine decarboxylase [Escherichia coli ATCC 8739], gi\|169756799\|gb\|... LDCI_ECOLI, DCLY... - Lysine decarboxylase, inducible (EC 4.1.1.18) (LDC) - Escherichia coli, (P23892) Lysine decarboxylas... gi\|157157750, gi... - gi\|157157750\|ref\|YP_001465630.1\| lysine decarboxylase homolog, constitutive [Escherichia coli E24377... gi\|168755315, gi... - gi\|189357416\|gb\|EDU75835.1\| lysine decarboxylase, constitutive [Escherichia coli O157:H7 str. EC4401... gi\|168760995, gi... - gi\|189368547\|gb\|EDU86963.1\| lysine decarboxylase, constitutive [Escherichia coli O157:H7 str. EC4501... gi\|189363955, gi... - gi\|189363955\|gb\|EDU82374.1\| lysine decarboxylase, constitutive [Escherichia coli O157:H7 str. EC4486... gi\|168774504, gi... - gi\|187769814\|gb\|EDU33658.1\| lysine decarboxylase, constitutive [Escherichia coli O157:H7 str. EC4196... gi\|217325100, gi... - gi\|217325100\|ref\|ZP_03441184.1\| lysine decarboxylase, constitutive [Escherichia coli O157:H7 str. TW... gi\|218363453, gi... - gi\|218556684\|ref\|YP_002389598.1\| lysine decarboxylase 1 [Escherichia coli IAI1], gi\|218363453\|emb\|CA... gi\|218697834, gi... - gi\|218697834\|ref\|YP_002405501.1\| lysine decarboxylase 1 [Escherichia coli 55989], gi\|218354566\|emb\|C... gi\|218434844, gi... - gi\|218707747\|ref\|YP_002415266.1\| lysine decarboxylase 1 [Escherichia coli UMN026], gi\|218434844\|emb\|... gi\|208813848, gi... - gi\|208813848\|ref\|ZP_03255177.1\| lysine decarboxylase, constitutive [Escherichia coli O157:H7 str. EC... gi\|208742075, gi... - gi\|208821952\|ref\|ZP_03262272.1\| lysine decarboxylase, constitutive [Escherichia coli O157:H7 str. EC... gi\|209160554, gi... - gi\|209399154\|ref\|YP_002273678.1\| lysine decarboxylase, constitutive [Escherichia coli O157:H7 str. E... gi\|209921622, gi... - gi\|209921622\|ref\|YP_002295706.1\| lysine decarboxylase [Escherichia coli SE11], gi\|209914881\|dbj\|BAG7... LDCI_ECO57 - Lysine decarboxylase, inducible OS=Escherichia coli O157:H7 GN=cadA PE=3 SV=1 EG10131 - lysine decarboxylase, acid-inducible / Lysine decarboxylase, inducible; decameric gi\|15804724, gi\|... - gi\|15804724\|ref\|NP_290765.1\| lysine decarboxylase 1 [Escherichia coli O157:H7 EDL933], gi\|12519108\|g...	610.0	[0..1]	[711..1]
gi\|91187424, gi\|... - gi\|91229245\|ref\|ZP_01262906.1\| lysine decarboxylase [Vibrio alginolyticus 12G01], gi\|91187424\|gb\|EAS...	609.0	[0..1]	[710..1]
gi\|28807916, gi\|... - gi\|44886080\|dbj\|BAD12083.1\| lysine decarboxylase [Vibrio parahaemolyticus], gi\|28807916\|dbj\|BAC61153... gi\|28807916, gi\|... - gi\|28899664\|ref\|NP_799269.1\| lysine decarboxylase [Vibrio parahaemolyticus RIMD 2210633], gi\|2880791...	609.0	[0..1]	[710..1]
gi\|110644490, gi... - gi\|110644490\|ref\|YP_672220.1\| lysine decarboxylase, inducible [Escherichia coli 536], gi\|110346082\|g...	608.0	[0..1]	[711..1]
gi\|12698732 - gi\|12698732\|gb\|AAK01664.1\|AF324470_2 lysine decarboxylase [Vibrio vulnificus] gi\|37199313, gi\|... - gi\|37680565\|ref\|NP_935174.1\| lysine decarboxylase [Vibrio vulnificus YJ016], gi\|37199313\|dbj\|BAC9514... gi\|161501814 - gi\|161501814\|ref\|NP_760922.2\| lysine decarboxylase [Vibrio vulnificus CMCP6]	607.0	[0..1]	[711..1]
gi\|229335232, gi... - gi\|229527224\|ref\|ZP_04416617.1\| lysine decarboxylase [Vibrio cholerae 12129(1)], gi\|229335232\|gb\|EEO... gi\|229521003, gi... - gi\|229521003\|ref\|ZP_04410424.1\| lysine decarboxylase [Vibrio cholerae TM 11079-80], gi\|229341888\|gb\|... gi\|254225651, gi... - gi\|254225651\|ref\|ZP_04919258.1\| lysine decarboxylase, inducible [Vibrio cholerae V51], gi\|194537158\|... gi\|75828257, gi\|... - gi\|75828257\|ref\|ZP_00757692.1\| COG1982: Arginine/lysine/ornithine decarboxylases [Vibrio cholerae O3... gi\|153801509, gi... - gi\|153801509\|ref\|ZP_01956095.1\| lysine decarboxylase, inducible [Vibrio cholerae MZO-3], gi\|12412291... gi\|75823526, gi\|... - gi\|75823526\|ref\|ZP_00753021.1\| COG1982: Arginine/lysine/ornithine decarboxylases [Vibrio cholerae RC... gi\|121630544, gi... - gi\|121727033\|ref\|ZP_01680224.1\| lysine decarboxylase, inducible [Vibrio cholerae V52], gi\|121630544\|... tr\|A2PRU6\|A2PRU6... - Lysine decarboxylase, inducible OS=Vibrio cholerae MZO-3 GN=cadA PE=4 SV=1, Lysine decarboxylase OS=... gi\|148874126, gi... - gi\|153830392\|ref\|ZP_01983059.1\| lysine decarboxylase, inducible [Vibrio cholerae 623-39], gi\|1488741... gi\|229512722, gi... - gi\|229512722\|ref\|ZP_04402190.1\| lysine decarboxylase [Vibrio cholerae TMA 21], gi\|229350232\|gb\|EEO15...	606.0	[0..1]	[711..23]
gi\|229353608, gi... - gi\|229509293\|ref\|ZP_04398776.1\| lysine decarboxylase [Vibrio cholerae B33], gi\|229353608\|gb\|EEO18545... gi\|254847122, gi... - gi\|75831188\|ref\|ZP_00760454.1\| COG1982: Arginine/lysine/ornithine decarboxylases [Vibrio cholerae MO... gi\|229516239, gi... - gi\|229516239\|ref\|ZP_04405687.1\| lysine decarboxylase [Vibrio cholerae RC9], gi\|229346665\|gb\|EEO11635... gi\|229369088, gi... - gi\|229606433\|ref\|YP_002877081.1\| lysine decarboxylase [Vibrio cholerae MJ-1236], gi\|229369088\|gb\|ACQ... gi\|9654692, gi\|1... - gi\|9654692\|gb\|AAF93456.1\| lysine decarboxylase, inducible [Vibrio cholerae O1 biovar El Tor str. N16... gi\|11280589 - pir\|\|E82342 lysine decarboxylase, inducible VC0281 [imported] - Vibrio cholerae (strain N16961 serog...	606.0	[0..1]	[711..23]

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Predicted Domain #1

Region A:
Residues: [1-713]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNIIAIMGPH GVFYKDEPIK ELESALVAQG FQIIWPQNSV DLLKFIEHNP RICGVIFDWD  60
   61 EYSLDLCSDI NQLNEYLPLY AFINTHSTMD VSVQDMRMAL WFFEYALGQA EDIAIRMRQY 120
  121 TDEYLDNITP PFTKALFTYV KERKYTFCTP GHMGGTAYQK SPVGCLFYDF FGGNTLKADV 180
  181 SISVTELGSL LDHTGPHLEA EEYIARTFGA EQSYIVTNGT STSNKIVGMY AAPSGSTLLI 240
  241 DRNCHKSLAH LLMMNDVVPV WLKPTRNALG ILGGIPRREF TRDSIEEKVA ATTQAQWPVH 300
  301 AVITNSTYDG LLYNTDWIKQ TLDVPSIHFD SAWVPYTHFH PIYQGKSGMS GERVAGKVIF 360
  361 ETQSTHKMLA ALSQASLIHI KGEYDEEAFN EAFMMHTTTS PSYPIVASVE TAAAMLRGNP 420
  421 GKRLINRSVE RALHFRKEVQ RLREESDGWF FDIWQPPQVD EAECWPVAPG EQWHGFNDAD 480
  481 ADHMFLDPVK VTILTPGMDE QGNMSEEGIP AALVAKFLDE RGIVVEKTGP YNLLFLFSIG 540
  541 IDKTKAMGLL RGLTEFKRSY DLNLRIKNML PDLYAEDPDF YRNMRIQDLA QGIHKLIRKH 600
  601 DLPGLMLRAF DTLPEMIMTP HQAWQRQIKG EVETIALEQL VGRVSANMIL PYPPGVPLLM 660
  661 PGEMLTKESR TVLDFLLMLC SVGQHYPGFE TDIHGAKQDE DGVYRVRVLK MAG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	119.0
Match:	1ordA
Description:	Ornithine decarboxylase N-terminal "wing" domain; Ornithine decarboxylase major domain; Ornithine decarboxylase C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
signal transducer activity	3.07847885826982	bayes_pls_golite062009
molecular transducer activity	3.07847885826982	bayes_pls_golite062009
two-component response regulator activity	2.37985305449443	bayes_pls_golite062009
catalytic activity	2.29878871754893	bayes_pls_golite062009
transferase activity	1.44093490824786	bayes_pls_golite062009
transferase activity, transferring nitrogenous groups	1.28316822767388	bayes_pls_golite062009
transaminase activity	1.24990480711889	bayes_pls_golite062009
L-aspartate:2-oxoglutarate aminotransferase activity	0.73470270006811	bayes_pls_golite062009
binding	0.252160165096264	bayes_pls_golite062009
pyridoxal phosphate binding	0.16957228630576	bayes_pls_golite062009
vitamin B6 binding	0.16957228630576	bayes_pls_golite062009
carbon-carbon lyase activity	0.11598778799668	bayes_pls_golite062009
4-aminobutyrate transaminase activity	0.0779403509221881	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: