YRC Public Data Repository - Protein Structure Prediction

Protein:	CYAY_ECOLI
Organism:	Escherichia coli
Length:	106 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CYAY_ECOLI.

Description	E-value	Query Range	Subject Range
CYAY_ECOHS - Protein CyaY OS=Escherichia coli O9:H4 (strain HS) GN=cyaY PE=3 SV=1	160.0	[0..1]	[106..1]
CYAY_DICCH - Protein CyaY OS=Dickeya chrysanthemi GN=cyaY PE=3 SV=1	160.0	[0..1]	[105..1]
CYAY_SALTY - Protein cyaY OS=Salmonella typhimurium GN=cyaY PE=3 SV=1 CYAY_SALTY - Protein CyaY OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=cyaY PE=3 SV=1 CYAY_SALTY - Protein CyaY OS=Salmonella typhimurium GN=cyaY PE=3 SV=1 gi\|200386498, gi... - gi\|200386498\|ref\|ZP_03213110.1\| iron donor protein CyaY [Salmonella enterica subsp. enterica serovar... gi\|205328147, gi... - gi\|205328147\|gb\|EDZ14911.1\| iron donor protein CyaY [Salmonella enterica subsp. enterica serovar 4,[...	159.0	[0..1]	[106..1]
gi\|213649581 - gi\|213649581\|ref\|ZP_03379634.1\| frataxin-like protein [Salmonella enterica subsp. enterica serovar T... gi\|213615880 - gi\|213615880\|ref\|ZP_03371706.1\| frataxin-like protein [Salmonella enterica subsp. enterica serovar T... CYAY_SALTI - Protein cyaY OS=Salmonella typhi GN=cyaY PE=3 SV=1 gi\|213977489 - gi\|213977489\|ref\|ZP_03404748.1\| frataxin-like protein [Salmonella enterica subsp. enterica serovar T... gi\|213855321 - gi\|213855321\|ref\|ZP_03383561.1\| frataxin-like protein [Salmonella enterica subsp. enterica serovar T... gi\|213420156 - gi\|213420156\|ref\|ZP_03353222.1\| frataxin-like protein [Salmonella enterica subsp. enterica serovar T... CYAY_SALTI - Protein CyaY OS=Salmonella typhi GN=cyaY PE=3 SV=1 gi\|213052019 - gi\|213052019\|ref\|ZP_03344897.1\| frataxin-like protein [Salmonella enterica subsp. enterica serovar T... gi\|213581098 - gi\|213581098\|ref\|ZP_03362924.1\| frataxin-like protein [Salmonella enterica subsp. enterica serovar T... gi\|213425405 - gi\|213425405\|ref\|ZP_03358155.1\| frataxin-like protein [Salmonella enterica subsp. enterica serovar T... CYAY_SALG2 - Protein CyaY OS=Salmonella gallinarum (strain 287/91 / NCTC 13346) GN=cyaY PE=3 SV=1 CYAY_SALDC - Protein CyaY OS=Salmonella dublin (strain CT_02021853) GN=cyaY PE=3 SV=1 gi\|29143680, gi\|... - gi\|29143680\|ref\|NP_807022.1\| frataxin-like protein [Salmonella enterica subsp. enterica serovar Typh... gi\|213021469 - gi\|213021469\|ref\|ZP_03335916.1\| frataxin-like protein [Salmonella enterica subsp. enterica serovar T... gi\|16762191 - gi\|16762191\|ref\|NP_457808.1\| frataxin-like protein [Salmonella enterica subsp. enterica serovar Typh... CYAY_SALEP - Protein CyaY OS=Salmonella enteritidis PT4 (strain P125109) GN=cyaY PE=3 SV=1 gi\|194459201, gi... - gi\|194472837\|ref\|ZP_03078821.1\| iron donor protein CyaY [Salmonella enterica subsp. enterica serovar... gi\|168233873, gi... - gi\|205332088\|gb\|EDZ18852.1\| iron donor protein CyaY [Salmonella enterica subsp. enterica serovar Ken... gi\|214002711 - gi\|214002711\|ref\|ZP_03413446.1\| frataxin-like protein [Salmonella enterica subsp. enterica serovar T...	159.0	[0..1]	[106..1]
gi\|77978546, gi\|... - gi\|77978546\|ref\|ZP_00833974.1\| COG1965: Protein implicated in iron transport, frataxin homolog [Yers...	159.0	[0..1]	[105..1]
gi\|238798587, gi... - gi\|77959873\|ref\|ZP_00823807.1\| COG1965: Protein implicated in iron transport, frataxin homolog [Yers...	158.0	[0..1]	[105..1]
CYAY_ECOL6 - Protein CyaY OS=Escherichia coli O6 GN=cyaY PE=3 SV=1 gi\|227834449, gi... - gi\|227888610\|ref\|ZP_04006415.1\| frataxin family protein [Escherichia coli 83972], gi\|227834449\|gb\|EE... CYAY_ECOL6 - Protein CyaY OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=cyaY PE=3 SV=1	158.0	[0..1]	[106..1]
gi\|45437819, gi\|... - gi\|45442952\|ref\|NP_994491.1\| frataxin-like protein [Yersinia pestis biovar Microtus str. 91001], gi\|... gi\|22124298, gi\|... - gi\|22124298\|ref\|NP_667721.1\| frataxin-like protein [Yersinia pestis KIM], gi\|21957070\|gb\|AAM83972.1\|...	158.0	[0..1]	[105..3]
gi\|238789379, gi... - gi\|77973627\|ref\|ZP_00829173.1\| COG1965: Protein implicated in iron transport, frataxin homolog [Yers...	158.0	[0..1]	[105..1]
CYAY_YERPS - Protein CyaY OS=Yersinia pseudotuberculosis GN=cyaY PE=3 SV=1 CYAY_YERPS - Protein CyaY OS=Yersinia pseudotuberculosis serotype I (strain IP32953) GN=cyaY PE=3 SV=1 CYAY_YERPB - Protein CyaY OS=Yersinia pseudotuberculosis serotype IB (strain PB1/+) GN=cyaY PE=3 SV=1 CYAY_YERP3 - Protein CyaY OS=Yersinia pseudotuberculosis serotype O:1b (strain IP 31758) GN=cyaY PE=3 SV=1	157.0	[0..1]	[105..1]

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Predicted Domain #1

Region A:
Residues: [1-106]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNDSEFHRLA DQLWLTIEER LDDWDGDSDI DCEINGGVLT ITFENGSKII INRQEPLHQV  60
   61 WLATKQGGYH FDLKGDEWIC DRSGETFWDL LEQAATQQAG ETVSFR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	36.69897
Match:	1soyA
Description:	Solution structure of the bacterial frataxin orthologue, CyaY
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
iron chaperone activity	3.17227948432879	bayes_pls_golite062009
ferrous iron binding	2.87116348009643	bayes_pls_golite062009
iron ion binding	1.73649603719014	bayes_pls_golite062009
2 iron, 2 sulfur cluster binding	1.65779154545819	bayes_pls_golite062009
binding	1.3933630277144	bayes_pls_golite062009
iron-sulfur cluster binding	1.29853952140883	bayes_pls_golite062009
metal cluster binding	1.29853952140883	bayes_pls_golite062009
protein binding	0.663327363466366	bayes_pls_golite062009
ferric iron binding	0.646221482297098	bayes_pls_golite062009
cation binding	0.454189472150568	bayes_pls_golite062009
metal ion binding	0.454189472150568	bayes_pls_golite062009
ion binding	0.447774858608436	bayes_pls_golite062009
metallochaperone activity	0.338980780497959	bayes_pls_golite062009
catalytic activity	0.276917867171685	bayes_pls_golite062009
transition metal ion binding	0.196973490836877	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: