YRC Public Data Repository - Protein Structure Prediction

Protein:	CSTA_ECOLI
Organism:	Escherichia coli
Length:	701 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CSTA_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|81244455, gi\|... - gi\|82543044\|ref\|YP_406991.1\| carbon starvation protein [Shigella boydii Sb227], gi\|81244455\|gb\|ABB65...	789.0	[0..1]	[701..1]
gi\|110614136, gi... - gi\|110804588\|ref\|YP_688108.1\| carbon starvation protein [Shigella flexneri 5 str. 8401], gi\|11061413...	786.0	[0..1]	[701..1]
gi\|110640829, gi... - gi\|110640829\|ref\|YP_668557.1\| carbon starvation protein A [Escherichia coli 536], gi\|110342421\|gb\|AB... gi\|91209645, gi\|... - gi\|91209645\|ref\|YP_539631.1\| carbon starvation protein A [Escherichia coli UTI89], gi\|91071219\|gb\|AB... gi\|117622820, gi... - gi\|117622820\|ref\|YP_851733.1\| carbon starvation protein [Escherichia coli APEC O1], gi\|115511944\|gb\|... gi\|26106976, gi\|... - gi\|26246577\|ref\|NP_752616.1\| carbon starvation protein A [Escherichia coli CFT073], gi\|26106976\|gb\|A... gi\|237707428, gi... - gi\|237707428\|ref\|ZP_04537909.1\| carbon starvation protein A [Escherichia sp. 3_2_53FAA], gi\|22689863... gi\|218368958, gi... - gi\|218698972\|ref\|YP_002406601.1\| carbon starvation protein [Escherichia coli IAI39], gi\|218368958\|em... gi\|227884421, gi... - gi\|227884421\|ref\|ZP_04002226.1\| carbon starvation protein A [Escherichia coli 83972], gi\|227838507\|g... gi\|218431030, gi... - gi\|218703933\|ref\|YP_002411452.1\| carbon starvation protein [Escherichia coli UMN026], gi\|218431030\|e... gi\|190907389, gi... - gi\|191172290\|ref\|ZP_03033832.1\| carbon starvation protein A [Escherichia coli F11], gi\|190907389\|gb\|... gi\|218557539, gi... - gi\|218557539\|ref\|YP_002390452.1\| carbon starvation protein [Escherichia coli S88], gi\|218364308\|emb\|...	786.0	[0..1]	[701..1]
gi\|74311133, gi\|... - gi\|74311133\|ref\|YP_309552.1\| carbon starvation protein [Shigella sonnei Ss046], gi\|73854610\|gb\|AAZ87...	785.0	[0..1]	[701..1]
gi\|168798155, gi... - gi\|189379257\|gb\|EDU97673.1\| carbon starvation protein A [Escherichia coli O157:H7 str. EC508], gi\|16... gi\|195936146 - gi\|195936146\|ref\|ZP_03081528.1\| carbon starvation protein [Escherichia coli O157:H7 str. EC4024] gi\|208809163, gi... - gi\|208809163\|ref\|ZP_03251500.1\| carbon starvation protein A [Escherichia coli O157:H7 str. EC4206], ... gi\|15829891, gi\|... - gi\|15829891\|ref\|NP_308664.1\| carbon starvation protein [Escherichia coli O157:H7 str. Sakai], gi\|133... gi\|208815410, gi... - gi\|208815410\|ref\|ZP_03256589.1\| carbon starvation protein A [Escherichia coli O157:H7 str. EC4045], ... gi\|209777476, gi... - pir\|\|A85559 carbon starvation protein [imported] - Escherichia coli (strain O157:H7, substrain EDL9... gi\|189360888, gi... - gi\|189360888\|gb\|EDU79307.1\| carbon starvation protein A [Escherichia coli O157:H7 str. EC4486], gi\|1... gi\|187769782, gi... - gi\|187769782\|gb\|EDU33626.1\| carbon starvation protein A [Escherichia coli O157:H7 str. EC4196], gi\|1... gi\|12513491, gi\|... - gi\|15800313\|ref\|NP_286325.1\| carbon starvation protein [Escherichia coli O157:H7 EDL933], gi\|1251349... gi\|189003060, gi... - gi\|189003060\|gb\|EDU72046.1\| carbon starvation protein A [Escherichia coli O157:H7 str. EC4076], gi\|1... gi\|15829891, gi\|... - gi\|15829891\|ref\|NP_308664.1\| carbon starvation protein [Escherichia coli O157:H7], gi\|13360095\|dbj\|B... gi\|189373685, gi... - gi\|189373685\|gb\|EDU92101.1\| carbon starvation protein A [Escherichia coli O157:H7 str. EC869], gi\|16... gi\|168747734, gi... - gi\|188017701\|gb\|EDU55823.1\| carbon starvation protein A [Escherichia coli O157:H7 str. EC4113], gi\|1... gi\|189358027, gi... - gi\|189358027\|gb\|EDU76446.1\| carbon starvation protein A [Escherichia coli O157:H7 str. EC4401], gi\|1... gi\|168760256, gi... - gi\|189369191\|gb\|EDU87607.1\| carbon starvation protein A [Escherichia coli O157:H7 str. EC4501], gi\|1... gi\|254791765, gi... - gi\|254791765\|ref\|YP_003076602.1\| carbon starvation protein [Escherichia coli O157:H7 str. TW14359], ... gi\|208822849, gi... - gi\|208822849\|ref\|ZP_03263167.1\| carbon starvation protein A [Escherichia coli O157:H7 str. EC4042], ... gi\|209398506, gi... - gi\|209398506\|ref\|YP_002269232.1\| carbon starvation protein A [Escherichia coli O157:H7 str. EC4115],... gi\|217320874, gi... - gi\|217324653\|ref\|ZP_03440737.1\| carbon starvation protein A [Escherichia coli O157:H7 str. TW14588],...	784.0	[0..1]	[701..1]
gi\|30040299, gi\|... - gi\|30062055\|ref\|NP_836226.1\| carbon starvation protein [Shigella flexneri 2a str. 2457T], gi\|3004029... gi\|24050751, gi\|... - gi\|24111943\|ref\|NP_706453.1\| carbon starvation protein [Shigella flexneri 2a str. 301], gi\|24050751\|...	782.0	[0..1]	[701..1]
gi\|167550871, gi... - gi\|205324139\|gb\|EDZ11978.1\| carbon starvation protein A [Salmonella enterica subsp. enterica serovar... gi\|205330944, gi... - gi\|205330944\|gb\|EDZ17708.1\| carbon starvation protein A [Salmonella enterica subsp. enterica serovar... gi\|16419111, gi\|... - gi\|16763977\|ref\|NP_459592.1\| carbon starvation protein [Salmonella typhimurium LT2], gi\|16419111\|gb\|... gi\|161615194, gi... - gi\|161615194\|ref\|YP_001589159.1\| hypothetical protein SPAB_02962 [Salmonella enterica subsp. enteric... gi\|206707869, gi... - gi\|207856066\|ref\|YP_002242717.1\| carbon starvation protein A [Salmonella enterica subsp. enterica se... gi\|224582433, gi... - gi\|224582433\|ref\|YP_002636231.1\| carbon starvation protein A [Salmonella enterica subsp. enterica se... gi\|198241952, gi... - gi\|198241952\|ref\|YP_002214594.1\| carbon starvation protein A [Salmonella enterica subsp. enterica se... gi\|200389766, gi... - gi\|200389766\|ref\|ZP_03216377.1\| carbon starvation protein A [Salmonella enterica subsp. enterica ser... gi\|197248133, gi... - gi\|197248133\|ref\|YP_002145574.1\| carbon starvation protein A [Salmonella enterica subsp. enterica se... gi\|197242780, gi... - gi\|197264525\|ref\|ZP_03164599.1\| carbon starvation protein A [Salmonella enterica subsp. enterica ser... gi\|194472762, gi... - gi\|194472762\|ref\|ZP_03078746.1\| carbon starvation protein A [Salmonella enterica subsp. enterica ser... gi\|194713457, gi... - gi\|194737955\|ref\|YP_002113718.1\| carbon starvation protein A [Salmonella enterica subsp. enterica se... gi\|194443275, gi... - gi\|194443275\|ref\|YP_002039841.1\| carbon starvation protein A [Salmonella enterica subsp. enterica se... gi\|194451073, gi... - gi\|194451073\|ref\|YP_002044632.1\| carbon starvation protein A [Salmonella enterica subsp. enterica se... gi\|195631606, gi... - gi\|195631606\|gb\|EDX50126.1\| carbon starvation protein A [Salmonella enterica subsp. enterica serovar... gi\|168818781, gi... - gi\|205344258\|gb\|EDZ31022.1\| carbon starvation protein A [Salmonella enterica subsp. enterica serovar... gi\|168240439, gi... - gi\|205340317\|gb\|EDZ27081.1\| carbon starvation protein A [Salmonella enterica subsp. enterica serovar... gi\|238911551 - gi\|238911551\|ref\|ZP_04655388.1\| carbon starvation protein A [Salmonella enterica subsp. enterica ser... gi\|168260891, gi... - gi\|205349761\|gb\|EDZ36392.1\| carbon starvation protein A [Salmonella enterica subsp. enterica serovar... gi\|205334079, gi... - gi\|205334079\|gb\|EDZ20843.1\| carbon starvation protein A [Salmonella enterica subsp. enterica serovar... lcl\|NC_016856.1_... - [gene=cstA] [protein=carbon starvation protein] [protein_id=YP_005236307.1] [location=661968..664073... gi\|168236587, gi... - gi\|197290276\|gb\|EDY29632.1\| carbon starvation protein A [Salmonella enterica subsp. enterica serovar...	774.0	[0..1]	[701..1]
gi\|16501851, gi\|... - gi\|25302242\|pir\|\|AB0576 carbon starvation protein A [imported] - Salmonella enterica subsp. enterica... gi\|213999498 - gi\|213999498\|ref\|ZP_03410233.1\| carbon starvation protein A [Salmonella enterica subsp. enterica ser... gi\|29138299, gi\|... - gi\|29142668\|ref\|NP_806010.1\| carbon starvation protein A [Salmonella enterica subsp. enterica serova... gi\|213424764 - gi\|213424764\|ref\|ZP_03357514.1\| carbon starvation protein A [Salmonella enterica subsp. enterica ser... gi\|213163857 - gi\|213163857\|ref\|ZP_03349567.1\| carbon starvation protein A [Salmonella enterica subsp. enterica ser... gi\|16759559 - gi\|16759559\|ref\|NP_455176.1\| carbon starvation protein A [Salmonella enterica subsp. enterica serova...	773.0	[0..1]	[701..1]
gi\|75194783 - gi\|75194783\|ref\|ZP_00704853.1\| COG1966: Carbon starvation protein, predicted membrane protein [Esche... gi\|75189638 - gi\|75189638\|ref\|ZP_00702905.1\| COG1966: Carbon starvation protein, predicted membrane protein [Esche...	771.0	[0..16]	[701..1]
gi\|75258664 - gi\|75258664\|ref\|ZP_00730071.1\| COG1966: Carbon starvation protein, predicted membrane protein [Esche... gi\|75210771 - gi\|75210771\|ref\|ZP_00710903.1\| COG1966: Carbon starvation protein, predicted membrane protein [Esche...	771.0	[0..16]	[701..1]

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Predicted Domain #1

Region A:
Residues: [1-154]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNKSGKYLVW TVLSVMGAFA LGYIALNRGE QINALWIVVA SVCIYLIAYR FYGLYIAKNV  60
   61 LAVDPTRMTP AVRHNDGLDY VPTDKKVLFG HHFAAIAGAG PLVGPVLAAQ MGYLPGMIWL 120
  121 LAGVVLAGAV QDFMVLFVST RRDGRSLGEL VKEE

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [155-316]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGPTAGVIAL VACFMIMVII LAVLAMIVVK ALTHSPWGTY TVAFTIPLAL FMGIYLRYLR  60
   61 PGRIGEVSVI GLVFLIFAII SGGWVAESPT WAPYFDFTGV QLTWMLVGYG FVAAVLPVWL 120
  121 LLAPRDYLST FLKIGTIVGL AVGILIMRPT LTMPALTKFV DG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	33.0
Match:	1oy6A
Description:	Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains; Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains; Multidrug efflux transporter AcrB transmembrane domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transporter activity	2.11813412631952	bayes_pls_golite062009
drug transmembrane transporter activity	1.70373034093714	bayes_pls_golite062009
	1.35307152666168	bayes_pls_golite062009
	0.981890900936533	bayes_pls_golite062009
transmembrane transporter activity	0.629021787695216	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [317-541]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TGPVWTGNLF PFLFITIACG AVSGFHALIS SGTTPKMLAN EGQACFIGYG GMLMESFVAI  60
   61 MALVSACIID PGVYFAMNSP MAVLAPAGTA DVVASAAQVV SSWGFSITPD TLNQIASEVG 120
  121 EQSIISRAGG APTLAVGMAY ILHGALGGMM DVAFWYHFAI LFEALFILTA VDAGTRAARF 180
  181 MLQDLLGVVS PGLKRTDSLP ANLLATALCV LAWGYFLHQG VVDPL

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [542-701]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGINTLWPLF GIANQMLAGM ALMLCAVVLF KMKRQRYAWV ALVPTAWLLI CTLTAGWQKA  60
   61 FSPDAKVGFL AIANKFQAMI DSGNIPSQYT ESQLAQLVFN NRLDAGLTIF FMVVVVVLAL 120
  121 FSIKTALAAL KDPKPTAKET PYEPMPENVE EIVAQAKGAH

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: