YRC Public Data Repository - Protein Structure Prediction

Protein:	COBC_ECOLI
Organism:	Escherichia coli
Length:	203 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COBC_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|134299758, gi... - gi\|88944800\|ref\|ZP_01148024.1\| Phosphoglycerate mutase/fructose-2,6-bisphosphatase [Desulfotomaculum...	210.0	[0..2]	[202..5]
gi\|146273747, gi... - gi\|98662370\|dbj\|GAA00697.1\| unnamed protein product [Pelotomaculum thermopropionicum SI], gi\|1476776...	208.0	[0..2]	[202..4]
gi\|83572867, gi\|... - gi\|83589953\|ref\|YP_429962.1\| phosphoglycerate mutase [Moorella thermoacetica ATCC 39073], gi\|8357286...	198.0	[0..2]	[201..5]
gi\|67917134, gi\|... - gi\|67917134\|ref\|ZP_00510806.1\| Phosphoglycerate/bisphosphoglycerate mutase [Clostridium thermocellum...	198.0	[0..3]	[199..38]
gi\|7451675 - pir\|\|A70471 phosphoglycerate mutase 1 - Aquifex aeolicus gi\|15606984, gi\|... - gi\|2984221\|gb\|AAC07750.1\| phosphoglycerate mutase [Aquifex aeolicus VF5], gi\|15606984\|ref\|NP_214366....	196.0	[0..1]	[201..2]
gi\|158320599, gi... - gi\|158320599\|ref\|YP_001513106.1\| phosphoglycerate mutase [Alkaliphilus oremlandii OhILAs], gi\|158140...	195.0	[0..6]	[199..1]
gi\|20807793, gi\|... - gi\|20807793\|ref\|NP_622964.1\| phosphoglycerate mutase/fructose-2,6-bisphosphatase [Thermoanaerobacter... gi\|20807793 - gi\|20807793\|ref\|NP_622964.1\| Phosphoglycerate mutase/fructose-2,6-bisphosphatase [Thermoanaerobacter...	193.0	[0..2]	[201..4]
gi\|73748492, gi\|... - gi\|73748492\|ref\|YP_307731.1\| alpha-ribazole-5-phosphate phosphatase [Dehalococcoides sp. CBDB1], gi\|...	191.0	[0..1]	[199..1]

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Predicted Domain #1

Region A:
Residues: [1-203]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLWLIRHGE TQANIDGLYS GHAPTPLTAR GIEQAQNLHT LLHGVSFDLV LCSELERAQH  60
   61 TARLVLSDRQ LPVQIIPELN EMFFGDWEMR HHRDLMQEDA ENYSAWCNDW QHAIPTNGEG 120
  121 FQAFSQRVER FIARLSEFQH YQNILVVSHQ GVLSLLIARL IGMPAEAMWH FRVDQGCWSA 180
  181 IDINQKFATL RVLNSRAIGV ENA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	47.30103
Match:	1e58A
Description:	Phosphoglycerate mutase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
phosphoglycerate mutase activity	2.29687410980387	bayes_pls_golite062009
phosphofructokinase activity	2.18786740610088	bayes_pls_golite062009
6-phosphofructo-2-kinase activity	1.92518572666112	bayes_pls_golite062009
fructose-2,6-bisphosphate 2-phosphatase activity	1.57622840153679	bayes_pls_golite062009
catalytic activity	1.37714494241232	bayes_pls_golite062009
hydrolase activity	0.959714350381009	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.924447963448235	bayes_pls_golite062009
intramolecular transferase activity, phosphotransferases	0.916759493094631	bayes_pls_golite062009
binding	0.911287540615709	bayes_pls_golite062009
carbohydrate kinase activity	0.815187968645556	bayes_pls_golite062009
carbohydrate phosphatase activity	0.542850952800002	bayes_pls_golite062009
isomerase activity	0.275500708652009	bayes_pls_golite062009
alpha-ribazole-5'-P phosphatase activity	0.174640929208739	bayes_pls_golite062009
intramolecular transferase activity	0.17180601190736	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: