YRC Public Data Repository - Protein Structure Prediction

Protein:	CKS1_LEIME
Organism:	Leishmania mexicana
Length:	99 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CKS1_LEIME.

Description	E-value	Query Range	Subject Range
gi\|154343611\|ref... - cyclin-dependent kinase regulatory subunit [Leishmania braziliensis MHOM/BR/75/M2904] gi\|146097182 - gi\|146097182\|ref\|XP_001468066.1\| cyclin-dependent kinase regulatory subunit [Leishmania infantum JPC... gi\|134065083, gi... - gi\|154343611\|ref\|XP_001567751.1\| cyclin-dependent kinase regulatory subunit [Leishmania braziliensis... gi\|134072432 - gi\|134072432\|emb\|CAM71142.1\| cyclin-dependent kinase regulatory subunit [Leishmania infantum] gi\|68128777 - gi\|68128777\|emb\|CAJ08910.1\| cyclin-dependent kinase regulatory subunit [Leishmania major] gi\|157874443 - gi\|157874443\|ref\|XP_001685705.1\| cyclin-dependent kinase regulatory subunit [Leishmania major]	172.0	[0..1]	[99..1]
gi\|74026260 - gi\|74026260\|ref\|XP_829696.1\| cyclin dependant kinase regulatory subunit [Trypanosoma brucei TREU927] gi\|23392951, gi\|... - gi\|70835082\|gb\|EAN80584.1\| cyclin dependant kinases regulatory subunit, putative [Trypanosoma brucei...	151.0	[0..6]	[99..3]
gi\|70880821 - gi\|70880821\|gb\|EAN93894.1\| cyclin-dependent kinases regulatory subunit, putative [Trypanosoma cruzi] gi\|71654242 - gi\|71654242\|ref\|XP_815745.1\| cyclin-dependent kinases regulatory subunit [Trypanosoma cruzi strain C...	149.0	[0..6]	[99..3]
gi\|27803876 - gi\|27803876\|gb\|AAO22151.1\| cyclin-dependent kinase regulatory subunit [Trypanosoma cruzi]	149.0	[0..6]	[99..3]
gi\|109505505 - gi\|109505505\|ref\|XP_001054024.1\| PREDICTED: similar to CDC28 protein kinase regulatory subunit 2 [Ra...	148.0	[0..22]	[98..95]
gi\|108879887, gi... - gi\|157106355\|ref\|XP_001649286.1\| cyclin-dependent kinases regulatory subunit. putative [Aedes aegypt...	142.0	[0..26]	[99..1]
AGAP009442-PA - cyclin-dependent kinase regulatory subunit CKS1\|protein_coding\|3R:33502440:33502844:1\|gene:AGAP00944... gi\|118777340, gi... - gi\|118777340\|ref\|XP_307855.3\| AGAP009442-PA [Anopheles gambiae str. PEST], gi\|116132904\|gb\|EAA03636....	141.0	[0..26]	[99..1]
gi\|66534763 - gi\|66534763\|ref\|XP_624975.1\| PREDICTED: similar to Cyclin-dependent kinase subunit 85A CG9790-PA [Ap...	140.0	[0..26]	[99..1]

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Predicted Domain #1

Region A:
Residues: [1-99]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPAKPAQDFF SLDANGQREA LIIIKKLQCK ILYSDKYYDD MFEYRHVILP KDLARLVPTS  60
   61 RLMSEMEWRQ LGVQQSQGWV HYMIHKPEPH VLLFKRPRT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	33.221849
Match:	1buhB
Description:	CksHs1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
protein binding	1.72385894854644	bayes_pls_golite062009
binding	1.27976774437131	bayes_pls_golite062009
cyclin-dependent protein kinase regulator activity	0.778971115132656	bayes_pls_golite062009
kinase regulator activity	0.498328649950238	bayes_pls_golite062009
protein kinase regulator activity	0.47491756269249	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: