YRC Public Data Repository - Protein Structure Prediction

Protein:	CHBR_ECOLI
Organism:	Escherichia coli
Length:	280 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CHBR_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|227885842, gi... - gi\|227885842\|ref\|ZP_04003647.1\| DNA-binding transcriptional regulator ChbR [Escherichia coli 83972],... gi\|218427240, gi... - gi\|218689676\|ref\|YP_002397888.1\| DNA-binding transcriptional regulator ChbR [Escherichia coli ED1a],... gi\|26108391, gi\|... - gi\|26247988\|ref\|NP_754028.1\| DNA-binding transcriptional regulator ChbR [Escherichia coli CFT073], g... gi\|75241390 - gi\|75241390\|ref\|ZP_00725241.1\| COG2207: AraC-type DNA-binding domain-containing proteins [Escherichi...	175.0	[0..1]	[280..1]
gi\|75513769 - gi\|75513769\|ref\|ZP_00736145.1\| COG2207: AraC-type DNA-binding domain-containing proteins [Escherichi... gi\|15831695, gi\|... - gi\|15831695\|ref\|NP_310468.1\| DNA-binding transcriptional regulator ChbR [Escherichia coli O157:H7 st... gi\|74311946, gi\|... - gi\|74311946\|ref\|YP_310365.1\| DNA-binding transcriptional regulator ChbR [Shigella sonnei Ss046], gi\|... gi\|254793353, gi... - gi\|254793353\|ref\|YP_003078190.1\| DNA-binding transcriptional dual regulator [Escherichia coli O157:H... gi\|209768690, gi... - pir\|\|E85782 hypothetical protein celD [imported] - Escherichia coli (strain O157:H7, substrain EDL9... gi\|12515751, gi\|... - gi\|15802146\|ref\|NP_288168.1\| DNA-binding transcriptional regulator ChbR [Escherichia coli O157:H7 ED... gi\|15831695, gi\|... - gi\|15831695\|ref\|NP_310468.1\| negative transcriptional regulator of cel operon [Escherichia coli O157... gi\|75227704 - gi\|75227704\|ref\|ZP_00714439.1\| COG2207: AraC-type DNA-binding domain-containing proteins [Escherichi... gi\|75236796 - gi\|75236796\|ref\|ZP_00720867.1\| COG2207: AraC-type DNA-binding domain-containing proteins [Escherichi... gi\|75195805 - gi\|75195805\|ref\|ZP_00705875.1\| COG2207: AraC-type DNA-binding domain-containing proteins [Escherichi... gi\|75210222 - gi\|75210222\|ref\|ZP_00710390.1\| COG2207: AraC-type DNA-binding domain-containing proteins [Escherichi... gi\|218705233, gi... - gi\|218705233\|ref\|YP_002412752.1\| DNA-binding transcriptional regulator ChbR [Escherichia coli UMN026... gi\|209919096, gi... - gi\|209919096\|ref\|YP_002293180.1\| DNA-binding transcriptional regulator ChbR [Escherichia coli SE11],... gi\|218361069, gi... - gi\|218554301\|ref\|YP_002387214.1\| DNA-binding transcriptional regulator ChbR [Escherichia coli IAI1],... gi\|218352025, gi... - gi\|218695293\|ref\|YP_002402960.1\| DNA-binding transcriptional regulator ChbR [Escherichia coli 55989]...	175.0	[0..1]	[280..1]
gi\|75190768 - gi\|75190768\|ref\|ZP_00704035.1\| COG2207: AraC-type DNA-binding domain-containing proteins [Escherichi...	174.0	[0..1]	[280..1]
gi\|75256137 - gi\|75256137\|ref\|ZP_00727833.1\| COG2207: AraC-type DNA-binding domain-containing proteins [Escherichi...	173.0	[0..1]	[280..1]
gi\|237705684, gi... - gi\|237705684\|ref\|ZP_04536165.1\| DNA-binding transcriptional regulator ChbR [Escherichia sp. 3_2_53FA... gi\|115513031, gi... - gi\|117623907\|ref\|YP_852820.1\| DNA-binding transcriptional regulator ChbR [Escherichia coli APEC O1],... gi\|218558603, gi... - gi\|218558603\|ref\|YP_002391516.1\| DNA-binding transcriptional regulator ChbR [Escherichia coli S88], ... gi\|91210949, gi\|... - gi\|91210949\|ref\|YP_540935.1\| DNA-binding transcriptional regulator ChbR [Escherichia coli UTI89], gi...	173.0	[0..1]	[280..1]
gi\|190907986, gi... - gi\|191171656\|ref\|ZP_03033203.1\| transcriptional regulator ChbR [Escherichia coli F11], gi\|190907986\|... gi\|110343447, gi... - gi\|110641855\|ref\|YP_669585.1\| DNA-binding transcriptional regulator ChbR [Escherichia coli 536], gi\|...	171.0	[0..2]	[280..1]
lcl\|NC_016856.1_... - [gene=celD] [protein=DNA-binding transcriptional regulator ChbR] [protein_id=YP_005237172.1] [locati... gi\|161363644, gi... - gi\|161614280\|ref\|YP_001588245.1\| DNA-binding transcriptional regulator ChbR [Salmonella enterica sub... gi\|194403886, gi... - gi\|194445223\|ref\|YP_002040575.1\| HTH-type transcriptional regulator ChbR [Salmonella enterica subsp.... gi\|194409629, gi... - gi\|194451325\|ref\|YP_002045323.1\| DNA-binding transcriptional regulator ChbR [Salmonella enterica sub... gi\|29137287, gi\|... - gi\|29141659\|ref\|NP_805001.1\| DNA-binding transcriptional regulator ChbR [Salmonella enterica subsp. ... gi\|16760580 - gi\|16760580\|ref\|NP_456197.1\| DNA-binding transcriptional regulator ChbR [Salmonella enterica subsp. ... gi\|25512722, gi\|... - gi\|25512722\|pir\|\|AF0708 probable cel operon repressor STY1798 [imported] - Salmonella enterica subsp... gi\|16419833, gi\|... - gi\|16764666\|ref\|NP_460281.1\| DNA-binding transcriptional regulator ChbR [Salmonella typhimurium LT2]... gi\|62127539, gi\|... - gi\|62179906\|ref\|YP_216323.1\| DNA-binding transcriptional regulator ChbR [Salmonella enterica subsp. ... gi\|205359358, gi... - gi\|205359358\|ref\|ZP_02669358.2\| HTH-type transcriptional regulator ChbR [Salmonella enterica subsp. ... gi\|205341613, gi... - gi\|205360002\|ref\|ZP_02833961.2\| HTH-type transcriptional regulator ChbR [Salmonella enterica subsp. ... gi\|205347561, gi... - gi\|205360698\|ref\|ZP_02685839.2\| HTH-type transcriptional regulator ChbR [Salmonella enterica subsp. ... gi\|224584170, gi... - gi\|224584170\|ref\|YP_002637968.1\| putative cel operon repressor [Salmonella enterica subsp. enterica ... gi\|204927500, gi... - gi\|204927500\|ref\|ZP_03218701.1\| HTH-type transcriptional regulator ChbR [Salmonella enterica subsp. ... gi\|205322960, gi... - gi\|205357231\|ref\|ZP_02346082.2\| HTH-type transcriptional regulator ChbR [Salmonella enterica subsp. ... gi\|205329826, gi... - gi\|205357751\|ref\|ZP_02572964.2\| HTH-type transcriptional regulator ChbR [Salmonella enterica subsp. ... gi\|205332637, gi... - gi\|205358647\|ref\|ZP_02658291.2\| HTH-type transcriptional regulator ChbR [Salmonella enterica subsp. ... gi\|197243392, gi... - gi\|197265137\|ref\|ZP_03165211.1\| HTH-type transcriptional regulator ChbR [Salmonella enterica subsp. ... gi\|197301138, gi... - gi\|197301138\|ref\|ZP_02664043.2\| HTH-type transcriptional regulator ChbR (Chb operon repressor) [Salm... gi\|197939849, gi... - gi\|198245333\|ref\|YP_002215809.1\| HTH-type transcriptional regulator ChbR [Salmonella enterica subsp.... gi\|200389890, gi... - gi\|200389890\|ref\|ZP_03216501.1\| HTH-type transcriptional regulator ChbR [Salmonella enterica subsp. ... gi\|194469200, gi... - gi\|194469200\|ref\|ZP_03075184.1\| HTH-type transcriptional regulator ChbR [Salmonella enterica subsp. ... gi\|194735027, gi... - gi\|194735027\|ref\|YP_002114335.1\| HTH-type transcriptional regulator ChbR [Salmonella enterica subsp.... gi\|195634317, gi... - gi\|195873237\|ref\|ZP_02697217.2\| HTH-type transcriptional regulator ChbR [Salmonella enterica subsp. ... gi\|197251765, gi... - gi\|197251765\|ref\|YP_002146720.1\| HTH-type transcriptional regulator ChbR [Salmonella enterica subsp....	170.0	[0..1]	[280..1]
gi\|83569661, gi\|... - gi\|83569661\|ref\|ZP_00921112.1\| COG2207: AraC-type DNA-binding domain-containing proteins [Shigella d...	170.0	[0..1]	[280..1]
gi\|56127956, gi\|... - gi\|56413699\|ref\|YP_150774.1\| DNA-binding transcriptional regulator ChbR [Salmonella enterica subsp. ... gi\|238910866 - gi\|238910866\|ref\|ZP_04654703.1\| DNA-binding transcriptional regulator ChbR [Salmonella enterica subs... gi\|213646013 - gi\|213646013\|ref\|ZP_03376066.1\| DNA-binding transcriptional regulator ChbR [Salmonella enterica subs... gi\|213580976 - gi\|213580976\|ref\|ZP_03362802.1\| DNA-binding transcriptional regulator ChbR [Salmonella enterica subs... gi\|213162886 - gi\|213162886\|ref\|ZP_03348596.1\| DNA-binding transcriptional regulator ChbR [Salmonella enterica subs...	166.0	[0..2]	[280..1]
gi\|146296375, gi... - gi\|82499254\|ref\|ZP_00884703.1\| Helix-turn-helix, AraC type [Caldicellulosiruptor saccharolyticus DSM...	164.0	[0..39]	[275..36]

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Predicted Domain #1

Region A:
Residues: [1-96]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMQPVINAPE IATAREQQLF NGKNFHVFIY NKTESISGLH QHDYYEFTLV LTGRYFQEIN  60
   61 GKRVLLERGD FVFIPLGSHH QSFYEFGATR ILNVGI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	3.69897
Match:	1vj2A
Description:	Crystal structure of a novel manganese-containing cupin (TM1459) from Thermotoga maritima at 1.65 A resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.77242843392921	bayes_pls_golite062009
transcription regulator activity	0.707930119310256	bayes_pls_golite062009
nucleic acid binding	0.437474993266492	bayes_pls_golite062009
DNA binding	0.241621391797808	bayes_pls_golite062009
binding	0.206341280654185	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [97-280]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKRFFEQHYL PLLPYCFVAS QVYRTNNAFL TYVETVISSL NFRETGLEEF VEMVTFYVIN  60
   61 RLRHYREEQV IDDVPQWLKS TVEKMHDKEQ FSESALENMV ALSAKSQEYL TRATQRYYGK 120
  121 TPMQIINEIR INFAKKQLEM TNYSVTDIAF EAGYSSPSLF IKTFKKLTSF TPKSYRKKLT 180
  181 EFNQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	8.0
Match:	1wpkA
Description:	Methylated Form of N-terminal Transcriptional Regulator Domain of Escherichia Coli Ada Protein
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: