YRC Public Data Repository - Protein Structure Prediction

Protein:	CBPA_ECOLI
Organism:	Escherichia coli
Length:	306 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CBPA_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|82703356, gi\|... - gi\|82703356\|ref\|YP_412922.1\| heat shock protein DnaJ [Nitrosospira multiformis ATCC 25196], gi\|82411...	311.0	[0..1]	[306..10]
gi\|53612269, gi\|... - gi\|67158732\|ref\|ZP_00419593.1\| DnaJ central domain (CXXCXGXG):Heat shock protein DnaJ, N-terminal:Ch... DNAJ_AZOVD - Chaperone protein DnaJ OS=Azotobacter vinelandii (strain DJ / ATCC BAA-1303) GN=dnaJ PE=3 SV=1	311.0	[0..1]	[306..1]
DNAJ_SALPA - Chaperone protein DnaJ OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=dnaJ PE=3 SV=3 DNAJ_SALPA - Chaperone protein DnaJ OS=Salmonella paratyphi A GN=dnaJ PE=2 SV=3 DNAJ_SALPK - Chaperone protein DnaJ OS=Salmonella paratyphi A (strain AKU_12601) GN=dnaJ PE=3 SV=1	310.0	[0..1]	[306..1]
gi\|60549564 - gi\|60549564\|gb\|AAX24096.1\| DnaJ [Pseudomonas putida]	309.0	[0..1]	[306..1]
gi\|194429152, gi... - gi\|75209619\|ref\|ZP_00709837.1\| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom...	309.0	[0..1]	[306..1]
tr\|I7C0C3\|I7C0C3... - Chaperone protein DnaJ OS=Pseudomonas putida (strain DOT-T1E) GN=dnaJ PE=3 SV=1 DNAJ_PSEP1 - Chaperone protein DnaJ OS=Pseudomonas putida (strain F1 / ATCC 700007) GN=dnaJ PE=3 SV=1	309.0	[0..1]	[306..1]
gi\|238782689, gi... - gi\|238782689\|ref\|ZP_04626719.1\| hypothetical protein yberc0001_9760 [Yersinia bercovieri ATCC 43970]... gi\|77961939, gi\|... - gi\|77961939\|ref\|ZP_00825767.1\| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom...	309.0	[0..1]	[306..1]
gi\|238795016, gi... - gi\|77976926\|ref\|ZP_00832391.1\| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom...	309.0	[0..1]	[306..1]
DNAJ_YERPA - Chaperone protein DnaJ OS=Yersinia pestis bv. Antiqua (strain Antiqua) GN=dnaJ PE=3 SV=1 gi\|166009061, gi... - gi\|166009061\|ref\|ZP_02229959.1\| chaperone protein DnaJ [Yersinia pestis biovar Antiqua str. E1979001... DNAJ_YERPN - Chaperone protein DnaJ OS=Yersinia pestis bv. Antiqua (strain Nepal516) GN=dnaJ PE=3 SV=1 gi\|165927315, gi... - gi\|165927315\|ref\|ZP_02223147.1\| chaperone protein DnaJ [Yersinia pestis biovar Orientalis str. F1991... gi\|167048930, gi... - gi\|167401548\|ref\|ZP_02307042.1\| chaperone protein DnaJ [Yersinia pestis biovar Antiqua str. UG05-045... gi\|166212081, gi... - gi\|166212081\|ref\|ZP_02238116.1\| chaperone protein DnaJ [Yersinia pestis biovar Antiqua str. B4200300... gi\|167054956, gi... - gi\|167426033\|ref\|ZP_02317786.1\| chaperone protein DnaJ [Yersinia pestis biovar Mediaevalis str. K197... gi\|166963234, gi... - gi\|167419240\|ref\|ZP_02310993.1\| chaperone protein DnaJ [Yersinia pestis biovar Orientalis str. MG05-... DNAJ_YERPB - Chaperone protein DnaJ OS=Yersinia pseudotuberculosis serotype IB (strain PB1/+) GN=dnaJ PE=3 SV=1 gi\|89102681, gi\|... - gi\|89102681\|ref\|ZP_01175297.1\| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom... DNAJ_YERPY - Chaperone protein DnaJ OS=Yersinia pseudotuberculosis serotype O:3 (strain YPIII) GN=dnaJ PE=3 SV=1 DNAJ_YERPS - Chaperone protein DnaJ OS=Yersinia pseudotuberculosis GN=dnaJ PE=3 SV=1 DNAJ_YERPG - Chaperone protein DnaJ OS=Yersinia pestis bv. Antiqua (strain Angola) GN=dnaJ PE=3 SV=1 DNAJ_YERPE - Chaperone protein DnaJ OS=Yersinia pestis GN=dnaJ PE=3 SV=1 gi\|149289903, gi... - gi\|150260495\|ref\|ZP_01917223.1\| chaperone protein DnaJ [Yersinia pestis CA88-4125], gi\|149289903\|gb\|... gi\|229836948, gi... - gi\|229836948\|ref\|ZP_04457113.1\| chaperone Hsp40, co-chaperone with DnaK [Yersinia pestis Pestoides A... gi\|45438312, gi\|... - gi\|45443443\|ref\|NP_994982.1\| chaperone protein DnaJ [Yersinia pestis biovar Microtus str. 91001], gi... DNAJ_YERPP - Chaperone protein DnaJ OS=Yersinia pestis (strain Pestoides F) GN=dnaJ PE=3 SV=1 gi\|229696722, gi... - gi\|229840356\|ref\|ZP_04460515.1\| chaperone Hsp40, co-chaperone with DnaK [Yersinia pestis biovar Orie... gi\|21960686, gi\|... - gi\|22127579\|ref\|NP_671002.1\| chaperone protein DnaJ [Yersinia pestis KIM], gi\|21960686\|gb\|AAM87253.1... gi\|229842436, gi... - gi\|229842436\|ref\|ZP_04462591.1\| chaperone Hsp40, co-chaperone with DnaK [Yersinia pestis biovar Orie... gi\|16120798, gi\|... - gi\|218927666\|ref\|YP_002345541.1\| chaperone protein DnaJ [Yersinia pestis CO92], gi\|16120798\|ref\|NP_4... DNAJ_YERPS - Chaperone protein DnaJ OS=Yersinia pseudotuberculosis serotype I (strain IP32953) GN=dnaJ PE=3 SV=1	308.0	[0..1]	[306..1]
gi\|77976156, gi\|... - gi\|77976156\|ref\|ZP_00831689.1\| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom...	308.0	[0..1]	[306..1]

Back

Predicted Domain #1

Region A:
Residues: [1-109]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELKDYYAIM GVKPTDDLKT IKTAYRRLAR KYHPDVSKEP DAEARFKEVA EAWEVLSDEQ  60
   61 RRAEYDQMWQ HRNDPQFNRQ FHHGDGQSFN AEDFDDIFSS IFGQHARQS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	21.045757
Match:	1bq0A
Description:	J-DOMAIN (RESIDUES 1-77) OF THE ESCHERICHIA COLI N-TERMINAL FRAGMENT (RESIDUES 1-104) OF THE MOLECULAR CHAPERONE DNAJ, NMR, 20 STRUCTURES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
unfolded protein binding	5.16965422989143	bayes_pls_golite062009
heat shock protein binding	2.17994194200939	bayes_pls_golite062009
binding	2.03854863870179	bayes_pls_golite062009
protein binding	1.63230390088325	bayes_pls_golite062009
chaperone binding	1.61155546076854	bayes_pls_golite062009
nucleic acid binding	1.01835792943261	bayes_pls_golite062009
transcription regulator activity	0.972380300832732	bayes_pls_golite062009
DNA binding	0.72916846057707	bayes_pls_golite062009
Hsp70 protein binding	0.541755903922701	bayes_pls_golite062009
catalytic activity	0.106988907594358	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [110-306]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RQRPATRGHD IEIEVAVFLE ETLTEHKRTI SYNLPVYNAF GMIEQEIPKT LNVKIPAGVG  60
   61 NGQRIRLKGQ GTPGENGGPN GDLWLVIHIA PHPLFDIVGQ DLEIVVPVSP WEAALGAKVT 120
  121 VPTLKESILL TIPPGSQAGQ RLRVKGKGLV SKKQTGDLYA VLKIVMPPKP DENTAALWQQ 180
  181 LADAQSSFDP RKDWGKA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	34.69897
Match:	2q2gA
Description:	No description for 2q2gA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: