YRC Public Data Repository - Protein Structure Prediction

Protein:	CAIA_ECOLI
Organism:	Escherichia coli
Length:	380 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CAIA_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|77996195, gi\|... - gi\|78044080\|ref\|YP_360183.1\| butyryl-CoA dehydrogenase [Carboxydothermus hydrogenoformans Z-2901], g...	477.0	[0..1]	[379..1]
gi\|221087039, gi... - gi\|221087039\|ref\|ZP_03556579.1\| acyl-CoA dehydrogenase domain protein [Geobacillus sp. Y412MC61], gi... gi\|229331248, gi... - gi\|229497822\|ref\|ZP_04391521.1\| acyl-CoA dehydrogenase domain protein [Geobacillus sp. Y412MC52], gi... gi\|56381770, gi\|... - gi\|56421928\|ref\|YP_149246.1\| acyl-CoA dehydrogenase [Geobacillus kaustophilus HTA426], gi\|56381770\|d...	467.0	[0..1]	[377..1]
gi\|89089326, gi\|... - gi\|89095580\|ref\|ZP_01168474.1\| acyl-CoA dehydrogenase [Bacillus sp. NRRL B-14911], gi\|89089326\|gb\|EA...	463.0	[0..1]	[377..1]
gi\|228670589, gi... - gi\|229112755\|ref\|ZP_04242287.1\| Acyl-CoA dehydrogenase [Bacillus cereus Rock1-15], gi\|228670589\|gb\|E... gi\|218160858, gi... - gi\|218232901\|ref\|YP_002370118.1\| acyl-CoA dehydrogenase [Bacillus cereus B4264], gi\|218160858\|gb\|ACK... gi\|228722321, gi... - gi\|229051012\|ref\|ZP_04194560.1\| Acyl-CoA dehydrogenase [Bacillus cereus AH676], gi\|228722321\|gb\|EEL7... gi\|228798087, gi... - gi\|228961605\|ref\|ZP_04123214.1\| Acyl-CoA dehydrogenase [Bacillus thuringiensis serovar pakistani str... gi\|229147881, gi... - gi\|229147881\|ref\|ZP_04276222.1\| Acyl-CoA dehydrogenase [Bacillus cereus BDRD-ST24], gi\|228635531\|gb\|... gi\|229130590, gi... - gi\|229130590\|ref\|ZP_04259546.1\| Acyl-CoA dehydrogenase [Bacillus cereus BDRD-Cer4], gi\|228652929\|gb\|... gi\|29898933, gi\|... - gi\|30023372\|ref\|NP_835003.1\| Acyl-CoA dehydrogenase, short-chain specific [Bacillus cereus ATCC 1457...	462.0	[0..1]	[377..1]
gi\|22778698, gi\|... - gi\|23100465\|ref\|NP_693932.1\| acyl-CoA dehydrogenase [Oceanobacillus iheyensis HTE831], gi\|22778698\|d...	461.0	[0..1]	[377..1]
gi\|42784517, gi\|... - gi\|42784517\|ref\|NP_981764.1\| acyl-CoA dehydrogenase [Bacillus cereus ATCC 10987], gi\|42740449\|gb\|AAS...	460.0	[0..1]	[377..1]
gi\|52140219, gi\|... - gi\|52140219\|ref\|YP_086610.1\| acyl-CoA dehydrogenase [Bacillus cereus E33L], gi\|51973688\|gb\|AAU15238....	460.0	[0..1]	[377..1]
gi\|217962830, gi... - gi\|217962830\|ref\|YP_002341408.1\| acyl-CoA dehydrogenase [Bacillus cereus AH187], gi\|217064522\|gb\|ACJ... gi\|221242872, gi... - gi\|222098813\|ref\|YP_002532871.1\| acyl-CoA dehydrogenase [Bacillus cereus Q1], gi\|221242872\|gb\|ACM155... gi\|47553562, gi\|... - gi\|47569766\|ref\|ZP_00240438.1\| acyl-CoA dehydrogenase, short-chain specific [Bacillus cereus G9241],... gi\|206745945, gi... - gi\|206975851\|ref\|ZP_03236762.1\| acyl-CoA dehydrogenase [Bacillus cereus H3081.97], gi\|206745945\|gb\|E... gi\|228771185, gi... - gi\|228988568\|ref\|ZP_04148655.1\| Acyl-CoA dehydrogenase [Bacillus thuringiensis serovar tochigiensis ... gi\|228641373, gi... - gi\|229142084\|ref\|ZP_04270609.1\| Acyl-CoA dehydrogenase [Bacillus cereus BDRD-ST26], gi\|228641373\|gb\|...	459.0	[0..1]	[377..1]

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Predicted Domain #1

Region A:
Residues: [1-380]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDFNLNDEQE LFVAGIRELM ASENWEAYFA ECDRDSVYPE RFVKALADMG IDSLLIPEEH  60
   61 GGLDAGFVTL AAVWMELGRL GAPTYVLYQL PGGFNTFLRE GTQEQIDKIM AFRGTGKQMW 120
  121 NSAITEPGAG SDVGSLKTTY TRRNGKIYLN GSKCFITSSA YTPYIVVMAR DGASPDKPVY 180
  181 TEWFVDMSKP GIKVTKLEKL GLRMDSCCEI TFDDVELDEK DMFGREGNGF NRVKEEFDHE 240
  241 RFLVALTNYG TAMCAFEDAA RYANQRVQFG EAIGRFQLIQ EKFAHMAIKL NSMKNMLYEA 300
  301 AWKADNGTIT SGDAAMCKYF CANAAFEVVD SAMQVLGGVG IAGNHRISRF WRDLRVDRVS 360
  361 GGSDEMQILT LGRAVLKQYR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	120.0
Match:	1jqiA
Description:	Butyryl-CoA dehydrogenase, C-domain; Butyryl-CoA dehydrogenase, NM domains
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
oxidoreductase activity, acting on the CH-CH group of donors	5.13294227430131	bayes_pls_golite062009
acyl-CoA dehydrogenase activity	5.02561832634415	bayes_pls_golite062009
oxidoreductase activity	2.85679762145175	bayes_pls_golite062009
catalytic activity	2.78550799248797	bayes_pls_golite062009
acyl-CoA oxidase activity	1.1340220799927	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: