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Catalysis of the reaction: 3-methylbutanoyl-CoA + ETF = 3-methylbut-2-enoyl-CoA + reduced ETF. Catalysis of the reaction: butanoyl-CoA + ETF = 2-butenoyl-CoA + reduced ETF. Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor, where the acyl group is a short branched chain fatty acid residue. Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. Catalysis of the reaction: 2-methylbutanoyl-CoA + acceptor = 2-methylbut-2-enoyl-CoA + reduced acceptor. Catalysis of the reaction: acyl-CoA + ETF = 2,3-dehydroacyl-CoA + reduced ETF. Catalysis of the reaction: glutaryl-CoA + acceptor = crotonoyl-CoA + CO2 + reduced acceptor. Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor, where the acyl group is a very long-chain fatty acid residue. Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor. Catalysis of the reaction: 4-hydroxybenzoyl-CoA + acceptor = benzoyl-CoA + reduced acceptor. Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor, where the acyl group is a medium-chain fatty acid residue. Catalysis of the reaction: benzoyl-CoA + donor-H2 + 2 ATP = cyclohexa-1,5-diene-1-carbonyl-CoA + acceptor + 2 ADP + 2 phosphate.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: acyl-CoA dehydrogenase activity
Acc: GO:0003995
Aspect: Molecular Function
Desc: Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor.
Synonyms:
  • acyl-CoA:acceptor 2,3-oxidoreductase activity
  • GO:0019109
  • acyl dehydrogenase activity
  • fatty acyl coenzyme A dehydrogenase activity
  • medium-chain acyl-coenzyme A dehydrogenase activity
  • acyl coenzyme A dehydrogenase activity
  • long-chain acyl coenzyme A dehydrogenase activity
  • general acyl CoA dehydrogenase activity
  • acyl CoA dehydrogenase activity
  • acyl-CoA reductase activity
  • medium-chain acyl-CoA dehydrogenase activity
  • fatty-acyl-CoA dehydrogenase activity
  • long-chain acyl-CoA dehydrogenase activity
  • acyl-CoA:(acceptor) 2,3-oxidoreductase activity
Proteins in PDR annotated with:
   This term: 138 [Search]
   Term or descendants: 159 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0003995 - acyl-CoA dehydrogenase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle