YRC Public Data Repository - Protein Structure Prediction

Protein:	BETI_ECOLI
Organism:	Escherichia coli
Length:	195 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BETI_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|94498978, gi\|... - gi\|94498978\|ref\|ZP_01305516.1\| Transcriptional regulator [Oceanobacter sp. RED65], gi\|94428610\|gb\|EA...	136.0	[0..1]	[194..1]
BETI_YERPB - HTH-type transcriptional regulator BetI OS=Yersinia pseudotuberculosis serotype IB (strain PB1/+) GN... gi\|167470820 - gi\|167470820\|ref\|ZP_02335524.1\| transcriptional regulator BetI [Yersinia pestis FV-1] gi\|15979230, gi\|... - gi\|218928331\|ref\|YP_002346206.1\| transcriptional regulator BetI [Yersinia pestis CO92], gi\|16121463\|... BETI_YERPS - HTH-type transcriptional regulator BetI OS=Yersinia pseudotuberculosis serotype I (strain IP32953) G... gi\|166211225, gi... - gi\|166211225\|ref\|ZP_02237260.1\| transcriptional regulator BetI [Yersinia pestis biovar Antiqua str. ... BETI_YERPA - HTH-type transcriptional regulator BetI OS=Yersinia pestis bv. Antiqua (strain Antiqua) GN=betI PE=3... gi\|165989512, gi... - gi\|166011564\|ref\|ZP_02232462.1\| transcriptional regulator BetI [Yersinia pestis biovar Antiqua str. ... BETI_YERPN - HTH-type transcriptional regulator BetI OS=Yersinia pestis bv. Antiqua (strain Nepal516) GN=betI PE=... gi\|167423859, gi... - gi\|167423859\|ref\|ZP_02315612.1\| transcriptional regulator BetI [Yersinia pestis biovar Mediaevalis s... gi\|167400332, gi... - gi\|167400332\|ref\|ZP_02305845.1\| transcriptional regulator BetI [Yersinia pestis biovar Antiqua str. ... gi\|165924487, gi... - gi\|165924487\|ref\|ZP_02220319.1\| transcriptional regulator BetI [Yersinia pestis biovar Orientalis st... gi\|229843211, gi... - gi\|229843211\|ref\|ZP_04463357.1\| TetR-family regulatory protein [Yersinia pestis biovar Orientalis st... gi\|229894048, gi... - gi\|229894048\|ref\|ZP_04509234.1\| TetR-family regulatory protein [Yersinia pestis Pestoides A], gi\|229... BETI_YERP3 - HTH-type transcriptional regulator BetI OS=Yersinia pseudotuberculosis serotype O:1b (strain IP 3175... gi\|229697473, gi... - gi\|229841107\|ref\|ZP_04461266.1\| TetR-family regulatory protein [Yersinia pestis biovar Orientalis st... BETI_YERPS - HTH-type transcriptional regulator BetI OS=Yersinia pseudotuberculosis GN=betI PE=3 SV=1 gi\|149366837, gi... - gi\|149366837\|ref\|ZP_01888871.1\| TetR-family regulatory protein [Yersinia pestis CA88-4125], gi\|14929... BETI_YERPP - HTH-type transcriptional regulator BetI OS=Yersinia pestis (strain Pestoides F) GN=betI PE=3 SV=1 BETI_YERPE - HTH-type transcriptional regulator BetI OS=Yersinia pestis GN=betI PE=3 SV=1	127.0	[0..1]	[192..1]
gi\|84386107, gi\|... - gi\|84386107\|ref\|ZP_00989136.1\| transcriptional regulator BetI [Vibrio splendidus 12B01], gi\|84378877...	127.0	[0..1]	[193..1]
gi\|88799551, gi\|... - gi\|88799551\|ref\|ZP_01115127.1\| Transcriptional regulator [Reinekea sp. MED297], gi\|88777636\|gb\|EAR08...	125.0	[0..1]	[192..1]
gi\|45440827, gi\|... - gi\|45440827\|ref\|NP_992366.1\| transcriptional regulator BetI [Yersinia pestis biovar Microtus str. 91...	125.0	[0..2]	[192..10]
gi\|23097975, gi\|... - gi\|23097975\|ref\|NP_691441.1\| transcriptional regulator [Oceanobacillus iheyensis HTE831], gi\|2277619...	123.0	[0..1]	[195..1]
gi\|86144744, gi\|... - gi\|86144744\|ref\|ZP_01063076.1\| transcriptional regulator BetI [Vibrio sp. MED222], gi\|85837643\|gb\|EA...	121.0	[0..1]	[193..1]
gi\|89047799, gi\|... - gi\|89076523\|ref\|ZP_01162834.1\| transcriptional regulator BetI [Photobacterium sp. SKA34], gi\|8904779...	120.0	[0..1]	[188..1]
gi\|33347443\|ref\|... - putative transcriptional repressor of bet genes [Escherichia coli K12], putative transcriptional rep... gi\|1657511 - gi\|1657511\|gb\|AAB18039.1\| regulatory protein [Escherichia coli] gi\|1657511\|gb\|AA... - regulatory protein [Escherichia coli]	120.0	[0..1]	[195..7]
gi\|83631775, gi\|... - gi\|83643732\|ref\|YP_432167.1\| transcriptional regulator [Hahella chejuensis KCTC 2396], gi\|83631775\|g...	120.0	[0..1]	[188..1]

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Predicted Domain #1

Region A:
Residues: [1-195]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPKLGMQSIR RRQLIDATLE AINEVGMHDA TIAQIARRAG VSTGIISHYF RDKNGLLEAT  60
   61 MRDITSQLRD AVLNRLHALP QGSAEQRLQA IVGGNFDETQ VSSAAMKAWL AFWASSMHQP 120
  121 MLYRLQQVSS RRLLSNLVSE FRRELPREQA QEAGYGLAAL IDGLWLRAAL SGKPLDKTRA 180
  181 NSLTRHFITQ HLPTD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	23.154902
Match:	1vi0A
Description:	Crystal structure of a transcriptional regulator
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	4.29755359385997	bayes_pls_golite062009
DNA binding	3.01268207226307	bayes_pls_golite062009
transcription factor activity	3.00408040212712	bayes_pls_golite062009
nucleic acid binding	2.9430921064275	bayes_pls_golite062009
binding	1.69234246404005	bayes_pls_golite062009
sequence-specific DNA binding	0.46503550280898	bayes_pls_golite062009
RNA polymerase II transcription factor activity	0.24108783215685	bayes_pls_golite062009
protein binding	0.111941607625758	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: