YRC Public Data Repository - Protein Structure Prediction

Protein:	ATP6_ECOLI
Organism:	Escherichia coli
Length:	271 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ATP6_ECOLI.

Description	E-value	Query Range	Subject Range
ATP6_SALCH - ATP synthase subunit a OS=Salmonella choleraesuis (strain SC-B67) GN=atpB PE=3 SV=1 gi\|238913124 - gi\|238913124\|ref\|ZP_04656961.1\| F0F1 ATP synthase subunit A [Salmonella enterica subsp. enterica ser... ATP6_SALPA - ATP synthase subunit a OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=atpB PE=3 SV=1 ATP6_SALCH - ATP synthase subunit a OS=Salmonella choleraesuis GN=atpB PE=3 SV=1 ATP6_SALTY - ATP synthase subunit a OS=Salmonella typhimurium GN=atpB PE=3 SV=1 ATP6_SALA4 - ATP synthase subunit a OS=Salmonella agona (strain SL483) GN=atpB PE=3 SV=1 ATP6_SALSV - ATP synthase subunit a OS=Salmonella schwarzengrund (strain CVM19633) GN=atpB PE=3 SV=1 gi\|194458415, gi... - gi\|194472051\|ref\|ZP_03078035.1\| ATP synthase F0, A subunit [Salmonella enterica subsp. enterica sero... ATP6_SALHS - ATP synthase subunit a OS=Salmonella heidelberg (strain SL476) GN=atpB PE=3 SV=1 gi\|29143943, gi\|... - gi\|29143943\|ref\|NP_807285.1\| F0F1 ATP synthase subunit A [Salmonella enterica subsp. enterica serova... gi\|200388972, gi... - gi\|200388972\|ref\|ZP_03215584.1\| ATP synthase F0, A subunit [Salmonella enterica subsp. enterica sero... gi\|16762455 - gi\|16762455\|ref\|NP_458072.1\| F0F1 ATP synthase subunit A [Salmonella enterica subsp. enterica serova... ATP6_SALDC - ATP synthase subunit a OS=Salmonella dublin (strain CT_02021853) GN=atpB PE=3 SV=1 ATP6_SALTI - ATP synthase subunit a OS=Salmonella typhi GN=atpB PE=3 SV=1 ATP6_SALPK - ATP synthase subunit a OS=Salmonella paratyphi A (strain AKU_12601) GN=atpB PE=3 SV=1 ATP6_SALTY - ATP synthase subunit a OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=atpB PE=3 ... gi\|197265871, gi... - gi\|197265871\|ref\|ZP_03165945.1\| ATP synthase F0, A subunit [Salmonella enterica subsp. enterica sero... gi\|197287676, gi... - gi\|197287676\|gb\|EDY27067.1\| ATP synthase F0, A subunit [Salmonella enterica subsp. enterica serovar ... gi\|205331669, gi... - gi\|205331669\|gb\|EDZ18433.1\| ATP synthase F0, A subunit [Salmonella enterica subsp. enterica serovar ... gi\|205327323, gi... - gi\|205327323\|gb\|EDZ14087.1\| ATP synthase F0, A subunit [Salmonella enterica subsp. enterica serovar ... ATP6_SALPB - ATP synthase subunit a OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=atpB PE=3 SV=1 ATP6_SALNS - ATP synthase subunit a OS=Salmonella newport (strain SL254) GN=atpB PE=3 SV=1 gi\|168823136, gi... - gi\|205340561\|gb\|EDZ27325.1\| ATP synthase F0, A subunit [Salmonella enterica subsp. enterica serovar ... gi\|168464794, gi... - gi\|195632259\|gb\|EDX50743.1\| ATP synthase F0, A subunit [Salmonella enterica subsp. enterica serovar ... ATP6_SALPB - ATP synthase subunit a OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=atpB PE=3 SV=1 gi\|205348284, gi... - gi\|205348284\|gb\|EDZ34915.1\| ATP synthase F0, A subunit [Salmonella enterica subsp. enterica serovar ... gi\|81416159 - gi\|81416159\|sp\|Q7CPE3.1\|ATP6_SALTY RecName: Full=ATP synthase subunit a; AltName: Full=F-ATPase subu... ATP6_SALPA - ATP synthase subunit a OS=Salmonella paratyphi A GN=atpB PE=3 SV=1 gi\|75479642 - gi\|75479642\|sp\|Q57HX3.1\|ATP6_SALCH RecName: Full=ATP synthase subunit a; AltName: Full=F-ATPase subu... ATP6_SALPC - ATP synthase subunit a OS=Salmonella paratyphi C (strain RKS4594) GN=atpB PE=3 SV=1 gi\|81628043 - gi\|81628043\|sp\|Q8XGC2.1\|ATP6_SALTI RecName: Full=ATP synthase subunit a; AltName: Full=F-ATPase subu... gi\|213052664 - gi\|213052664\|ref\|ZP_03345542.1\| F0F1 ATP synthase subunit A [Salmonella enterica subsp. enterica ser... ATP6_SALEP - ATP synthase subunit a OS=Salmonella enteritidis PT4 (strain P125109) GN=atpB PE=3 SV=1 lcl\|NC_016856.1_... - [gene=atpB] [protein=F0F1 ATP synthase subunit A] [protein_id=YP_005240139.1] [location=complement(4... ATP6_SALG2 - ATP synthase subunit a OS=Salmonella gallinarum (strain 287/91 / NCTC 13346) GN=atpB PE=3 SV=1 gi\|204928835, gi... - gi\|204928835\|ref\|ZP_03220034.1\| ATP synthase F0, A subunit [Salmonella enterica subsp. enterica sero... gi\|214001330 - gi\|214001330\|ref\|ZP_03412065.1\| F0F1 ATP synthase subunit A [Salmonella enterica subsp. enterica ser... gi\|213649864 - gi\|213649864\|ref\|ZP_03379917.1\| F0F1 ATP synthase subunit A [Salmonella enterica subsp. enterica ser... gi\|213427464 - gi\|213427464\|ref\|ZP_03360214.1\| F0F1 ATP synthase subunit A [Salmonella enterica subsp. enterica ser... gi\|213418552 - gi\|213418552\|ref\|ZP_03351618.1\| F0F1 ATP synthase subunit A [Salmonella enterica subsp. enterica ser...	208.0	[0..1]	[271..1]
gi\|254847266, gi... - gi\|75829191\|ref\|ZP_00758503.1\| COG0356: F0F1-type ATP synthase, subunit a [Vibrio cholerae MO10], gi... ATP6_VIBC3 - ATP synthase subunit a OS=Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O39... gi\|116219392, gi... - gi\|75818738\|ref\|ZP_00748866.1\| COG0356: F0F1-type ATP synthase, subunit a [Vibrio cholerae V51], gi\|... gi\|121729381, gi... - gi\|75814914\|ref\|ZP_00745454.1\| COG0356: F0F1-type ATP synthase, subunit a [Vibrio cholerae V52], gi\|... gi\|121591533, gi... - gi\|121591533\|ref\|ZP_01678796.1\| ATP synthase F0, A subunit [Vibrio cholerae 2740-80], gi\|121546618\|g... gi\|124116207, gi... - gi\|153212981\|ref\|ZP_01948575.1\| ATP synthase F0, A subunit [Vibrio cholerae 1587], gi\|124116207\|gb\|E... gi\|153820049, gi... - gi\|153820049\|ref\|ZP_01972716.1\| ATP synthase F0, A subunit [Vibrio cholerae NCTC 8457], gi\|126509406... gi\|153821977, gi... - gi\|229508635\|ref\|ZP_04398130.1\| ATP synthase A chain [Vibrio cholerae B33], gi\|229354349\|gb\|EEO19277... ATP6_VIBCM - ATP synthase subunit a OS=Vibrio cholerae serotype O1 (strain M66-2) GN=atpB PE=3 SV=1 gi\|229508283, gi... - gi\|229508283\|ref\|ZP_04397787.1\| ATP synthase A chain [Vibrio cholerae BX 330286], gi\|229354556\|gb\|EE... gi\|229347063, gi... - gi\|229515963\|ref\|ZP_04405420.1\| ATP synthase A chain [Vibrio cholerae TMA 21], gi\|229347063\|gb\|EEO12... gi\|229517149, gi... - gi\|229517149\|ref\|ZP_04406595.1\| ATP synthase A chain [Vibrio cholerae RC9], gi\|229346212\|gb\|EEO11184... gi\|229342753, gi... - gi\|229520159\|ref\|ZP_04409586.1\| ATP synthase A chain [Vibrio cholerae TM 11079-80], gi\|229342753\|gb\|... gi\|229606557, gi... - gi\|229606557\|ref\|YP_002877205.1\| ATP synthase A chain [Vibrio cholerae MJ-1236], gi\|229369212\|gb\|ACQ... gi\|150422987, gi... - gi\|254291142\|ref\|ZP_04961939.1\| ATP synthase F0, A subunit [Vibrio cholerae AM-19226], gi\|197751562\|... ATP6_VIBCH - ATP synthase subunit a OS=Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) GN=a... gi\|153827198, gi... - gi\|153827198\|ref\|ZP_01979865.1\| ATP synthase F0, A subunit [Vibrio cholerae MZO-2], gi\|149738921\|gb\|... ATP6_VIBCH - ATP synthase subunit a OS=Vibrio cholerae GN=atpB PE=3 SV=1	206.0	[0..3]	[271..5]
gi\|148143 - gi\|148143\|gb\|AAA24740.1\| ATPase, a subunit (EC 3.6.1.3)	204.0	[0..1]	[271..1]
ATP6_SHIDS - ATP synthase subunit a OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=atpB PE=3 SV=1	204.0	[0..1]	[271..1]
gi\|24054300, gi\|... - gi\|24115041\|ref\|NP_709551.1\| F0F1 ATP synthase subunit A [Shigella flexneri 2a str. 301], gi\|2405430... gi\|30043218, gi\|... - gi\|30064957\|ref\|NP_839128.1\| F0F1 ATP synthase subunit A [Shigella flexneri 2a str. 2457T], gi\|30043... ATP6_SHIFL - ATP synthase subunit a OS=Shigella flexneri GN=atpB PE=3 SV=1 ATP6_SHIF8 - ATP synthase subunit a OS=Shigella flexneri serotype 5b (strain 8401) GN=atpB PE=3 SV=1	204.0	[0..1]	[271..1]
gi\|6625697\|gb\|AA... - ATP synthase subunit a [Salmonella typhimurium] gi\|6625697 - gi\|6625697\|gb\|AAF19356.1\|AF188265_2 ATP synthase subunit a [Salmonella typhimurium]	204.0	[0..1]	[271..1]
ATP6_ECOUT - ATP synthase subunit a OS=Escherichia coli (strain UTI89 / UPEC) GN=atpB PE=3 SV=1 gi\|191170564, gi... - gi\|191170564\|ref\|ZP_03032117.1\| ATP synthase F0, A subunit [Escherichia coli F11], gi\|190909372\|gb\|E... ATP6_ECO27 - ATP synthase subunit a OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=atpB PE=3 SV=1 ATP6_ECOSM - ATP synthase subunit a OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=atpB PE=3 SV=1 ATP6_ECOL6 - ATP synthase subunit a OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=atpB PE=3 S... ATP6_ECOK1 - ATP synthase subunit a OS=Escherichia coli O1:K1 / APEC GN=atpB PE=3 SV=1 ATP6_ECOL5 - ATP synthase subunit a OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=atpB PE=3 SV=1 gi\|227839238, gi... - gi\|227883960\|ref\|ZP_04001765.1\| H(+)-transporting two-sector ATPase [Escherichia coli 83972], gi\|227... sp\|B7UMK3\|ATP6_ECO27 - ATP synthase subunit a OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=atpB PE=3 SV=1 gi\|237703539, gi... - gi\|237703539\|ref\|ZP_04534020.1\| ATP synthase subunit A [Escherichia sp. 3_2_53FAA], gi\|226902803\|gb\|... ATP6_ECOLU - ATP synthase subunit a OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) GN=atpB PE=3 SV=1 ATP6_ECOL6 - ATP synthase subunit a OS=Escherichia coli O6 GN=atpB PE=3 SV=1 ATP6_ECO81 - ATP synthase subunit a OS=Escherichia coli O81 (strain ED1a) GN=atpB PE=3 SV=1 ATP6_ECO7I - ATP synthase subunit a OS=Escherichia coli O7:K1 (strain IAI39 / ExPEC) GN=atpB PE=3 SV=1 ATP6_ESCF3 - ATP synthase subunit a OS=Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73) GN=at... ATP6_ECO45 - ATP synthase subunit a OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=atpB PE=3 SV=1	204.0	[0..1]	[271..1]
ATP6_VIBAL - ATP synthase subunit a OS=Vibrio alginolyticus GN=atpB PE=3 SV=1 gi\|91226232, gi\|... - gi\|91226232\|ref\|ZP_01261072.1\| F0F1 ATP synthase subunit A [Vibrio alginolyticus 12G01], gi\|91189243... gi\|254229971, gi... - gi\|75855550\|ref\|ZP_00763198.1\| COG0356: F0F1-type ATP synthase, subunit a [Vibrio sp. Ex25], gi\|2542...	202.0	[0..3]	[270..5]
gi\|149748126, gi... - gi\|153838503\|ref\|ZP_01991170.1\| ATP synthase a chain [Vibrio parahaemolyticus AQ3810], gi\|149748126\|... ATP6_VIBPA - ATP synthase subunit a OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) GN=atpB PE=3 ... ATP6_VIBPA - ATP synthase subunit a OS=Vibrio parahaemolyticus GN=atpB PE=3 SV=1	202.0	[0..3]	[270..5]
ATP6_YERPB - ATP synthase subunit a OS=Yersinia pseudotuberculosis serotype IB (strain PB1/+) GN=atpB PE=3 SV=1 ATP6_YERPY - ATP synthase subunit a OS=Yersinia pseudotuberculosis serotype O:3 (strain YPIII) GN=atpB PE=3 SV=1 gi\|229839837, gi... - gi\|229839837\|ref\|ZP_04459996.1\| F0 sector of membrane-bound ATP synthase, subunit a [Yersinia pestis... gi\|229896798, gi... - gi\|229896798\|ref\|ZP_04511961.1\| F0 sector of membrane-bound ATP synthase, subunit a [Yersinia pestis... gi\|229691260, gi... - gi\|229841921\|ref\|ZP_04462077.1\| F0 sector of membrane-bound ATP synthase, subunit a [Yersinia pestis... ATP6_YERP3 - ATP synthase subunit a OS=Yersinia pseudotuberculosis serotype O:1b (strain IP 31758) GN=atpB PE=3 S... gi\|149290347, gi... - gi\|150260939\|ref\|ZP_01917667.1\| ATP synthase subunit B protein [Yersinia pestis CA88-4125], gi\|14929... ATP6_YERPP - ATP synthase subunit a OS=Yersinia pestis (strain Pestoides F) GN=atpB PE=3 SV=1 ATP6_YERPS - ATP synthase subunit a OS=Yersinia pseudotuberculosis GN=atpB PE=3 SV=1 ATP6_YERPN - ATP synthase subunit a OS=Yersinia pestis bv. Antiqua (strain Nepal516) GN=atpB PE=3 SV=1 ATP6_YERPA - ATP synthase subunit a OS=Yersinia pestis bv. Antiqua (strain Antiqua) GN=atpB PE=3 SV=1 gi\|21961157, gi\|... - gi\|22128009\|ref\|NP_671432.1\| F0F1 ATP synthase subunit A [Yersinia pestis KIM], gi\|21961157\|gb\|AAM87... ATP6_YERPE - ATP synthase subunit a OS=Yersinia pestis GN=atpB PE=3 SV=1 ATP6_YERPS - ATP synthase subunit a OS=Yersinia pseudotuberculosis serotype I (strain IP32953) GN=atpB PE=3 SV=1 gi\|45443757, gi\|... - gi\|45443757\|ref\|NP_995296.1\| F0F1 ATP synthase subunit A [Yersinia pestis biovar Microtus str. 91001... gi\|115349714, gi... - gi\|218931103\|ref\|YP_002348978.1\| F0F1 ATP synthase subunit A [Yersinia pestis CO92], gi\|16124235\|ref...	201.0	[0..2]	[271..4]

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Predicted Domain #1

Region A:
Residues: [1-66]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASENMTPQD YIGHHLNNLQ LDLRTFSLVD PQNPPATFWT INIDSMFFSV VLGLLFLVLF  60
   61 RSVAKK

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [67-271]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ATSGVPGKFQ TAIELVIGFV NGSVKDMYHG KSKLIAPLAL TIFVWVFLMN LMDLLPIDLL  60
   61 PYIAEHVLGL PALRVVPSAD VNVTLSMALG VFILILFYSI KMKGIGGFTK ELTLQPFNHW 120
  121 AFIPVNLILE GVSLLSKPVS LGLRLFGNMY AGELIFILIA GLLPWWSQWI LNVPWAIFHI 180
  181 LIITLQAFIF MVLTIVYLSM ASEEH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	32.154902
Match:	1c17M
Description:	F1F0 ATP synthase subunit A
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrogen ion transporting ATP synthase activity, rotational mechanism	14.916062574431	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	13.3765277511271	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	11.6266555949852	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	10.5141571800158	bayes_pls_golite062009
cation transmembrane transporter activity	6.7755175807552	bayes_pls_golite062009
ion transmembrane transporter activity	6.66886754588748	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	6.24164033661356	bayes_pls_golite062009
proton-transporting ATPase activity, rotational mechanism	5.34968915140418	bayes_pls_golite062009
transporter activity	4.44683838532142	bayes_pls_golite062009
substrate-specific transporter activity	4.37473908570954	bayes_pls_golite062009
transmembrane transporter activity	4.36056336888635	bayes_pls_golite062009
cation-transporting ATPase activity	3.33662712450334	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions	1.11865103919948	bayes_pls_golite062009
primary active transmembrane transporter activity	0.517601509369888	bayes_pls_golite062009
active transmembrane transporter activity	0.511311810386796	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	0.510137962484563	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	0.476924701765357	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	0.473395661531507	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	0.473285892250811	bayes_pls_golite062009
catalytic activity	0.276917867171685	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.242742762516199	bayes_pls_golite062009
pyrophosphatase activity	0.201337507209354	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.191294406773539	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.188721983770471	bayes_pls_golite062009
ATPase activity, coupled	0.110491424400621	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: