YRC Public Data Repository - Protein Structure Prediction

Protein:	ARGR_ECOLI
Organism:	Escherichia coli
Length:	156 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ARGR_ECOLI.

Description	E-value	Query Range	Subject Range
sp\|B7UJW9\|ARGR_ECO27 - Arginine repressor OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=argR PE=3 SV=1 ARGR_ECOUT - Arginine repressor OS=Escherichia coli (strain UTI89 / UPEC) GN=argR PE=3 SV=1 gi\|190905882, gi... - gi\|75237908\|ref\|ZP_00721919.1\| COG1438: Arginine repressor [Escherichia coli F11], gi\|191173832\|ref\|... ARGR_ECOL6 - Arginine repressor OS=Escherichia coli O6 GN=argR PE=3 SV=1 ARGR_ECOL5 - Arginine repressor OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=argR PE=3 SV=1 gi\|109389944, gi... - gi\|109389984\|gb\|ABG29721.1\| arginine biosynthesis repressor [Escherichia coli], gi\|109389982\|gb\|ABG2... gi\|237706016, gi... - gi\|237706016\|ref\|ZP_04536497.1\| arginine repressor [Escherichia sp. 3_2_53FAA], gi\|226899056\|gb\|EEH8... gi\|227835348, gi... - gi\|227887952\|ref\|ZP_04005757.1\| arginine repressor [Escherichia coli 83972], gi\|227835348\|gb\|EEJ4581... ARGR_ECO27 - Arginine repressor OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=argR PE=3 SV=1 ARGR_ECOL6 - Arginine repressor OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=argR PE=3 SV=1 ARGR_ECOK1 - Arginine repressor OS=Escherichia coli O1:K1 / APEC GN=argR PE=3 SV=1 ARGR_ECO45 - Arginine repressor OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=argR PE=3 SV=1 ARGR_ECO81 - Arginine repressor OS=Escherichia coli O81 (strain ED1a) GN=argR PE=3 SV=1	205.0	[0..1]	[156..1]
gi\|37678650, gi\|... - gi\|37678650\|ref\|NP_933259.1\| arginine repressor [Vibrio vulnificus YJ016], gi\|37197390\|dbj\|BAC93230....	203.0	[0..1]	[153..55]
ARGR_VIBCB - Arginine repressor OS=Vibrio campbellii (strain ATCC BAA-1116 / BB120) GN=argR PE=3 SV=1 gi\|148869250, gi... - gi\|153834402\|ref\|ZP_01987069.1\| arginine repressor [Vibrio harveyi HY01], gi\|148869250\|gb\|EDL68272.1... ARGR_VIBPA - Arginine repressor OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) GN=argR PE=3 SV=1 ARGR_VIBPA - Arginine repressor OS=Vibrio parahaemolyticus GN=argR PE=3 SV=1	201.0	[0..1]	[153..1]
gi\|197287879, gi... - gi\|197287879\|gb\|EDY27267.1\| arginine repressor [Salmonella enterica subsp. enterica serovar Schwarze... gi\|168233942, gi... - gi\|205332027\|gb\|EDZ18791.1\| arginine repressor [Salmonella enterica subsp. enterica serovar Kentucky... gi\|205348402, gi... - gi\|205348402\|gb\|EDZ35033.1\| arginine repressor [Salmonella enterica subsp. enterica serovar Hadar st... gi\|205336187, gi... - gi\|205336187\|gb\|EDZ22951.1\| arginine repressor [Salmonella enterica subsp. enterica serovar Heidelbe... gi\|167993943, gi... - gi\|205328080\|gb\|EDZ14844.1\| arginine repressor [Salmonella enterica subsp. enterica serovar 4,[5],12... gi\|205322527, gi... - gi\|205322527\|gb\|EDZ10366.1\| arginine repressor [Salmonella enterica subsp. enterica serovar Saintpau... gi\|238913559 - gi\|238913559\|ref\|ZP_04657396.1\| arginine repressor [Salmonella enterica subsp. enterica serovar Tenn... ARGR_SALEP - Arginine repressor OS=Salmonella enteritidis PT4 (strain P125109) GN=argR PE=3 SV=1 ARGR_SALG2 - Arginine repressor OS=Salmonella gallinarum (strain 287/91 / NCTC 13346) GN=argR PE=3 SV=1 gi\|213425840 - gi\|213425840\|ref\|ZP_03358590.1\| arginine repressor [Salmonella enterica subsp. enterica serovar Typh... gi\|213052251 - gi\|213052251\|ref\|ZP_03345129.1\| arginine repressor [Salmonella enterica subsp. enterica serovar Typh... ARGR_SALDC - Arginine repressor OS=Salmonella dublin (strain CT_02021853) GN=argR PE=3 SV=1 ARGR_SALPK - Arginine repressor OS=Salmonella paratyphi A (strain AKU_12601) GN=argR PE=3 SV=1 gi\|204319953, gi... - gi\|204931186\|ref\|ZP_03221980.1\| arginine repressor [Salmonella enterica subsp. enterica serovar Javi... gi\|200386762, gi... - gi\|200386762\|ref\|ZP_03213374.1\| arginine repressor [Salmonella enterica subsp. enterica serovar Virc... ARGR_SALSV - Arginine repressor OS=Salmonella schwarzengrund (strain CVM19633) GN=argR PE=3 SV=1 gi\|194472023, gi... - gi\|194472023\|ref\|ZP_03078007.1\| arginine repressor [Salmonella enterica subsp. enterica serovar Kent... gi\|197264195, gi... - gi\|197264195\|ref\|ZP_03164269.1\| arginine repressor [Salmonella enterica subsp. enterica serovar Sain... ARGR_SALA4 - Arginine repressor OS=Salmonella agona (strain SL483) GN=argR PE=3 SV=1 gi\|205340903, gi... - gi\|205340903\|gb\|EDZ27667.1\| arginine repressor [Salmonella enterica subsp. enterica serovar Weltevre... ARGR_SALTY - Arginine repressor OS=Salmonella typhimurium GN=argR PE=1 SV=1 gi\|195633143, gi... - gi\|195633143\|gb\|EDX51557.1\| arginine repressor [Salmonella enterica subsp. enterica serovar Newport ... ARGR_SALPA - Arginine repressor OS=Salmonella paratyphi A GN=argR PE=3 SV=1 ARGR_SALHS - Arginine repressor OS=Salmonella heidelberg (strain SL476) GN=argR PE=3 SV=1 ARGR_SALCH - Arginine repressor OS=Salmonella choleraesuis GN=argR PE=3 SV=1 ARGR_SALNS - Arginine repressor OS=Salmonella newport (strain SL254) GN=argR PE=3 SV=1 ARGR_SALTY - Arginine repressor OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=argR PE=1 SV=1 gi\|29143608, gi\|... - gi\|29143608\|ref\|NP_806950.1\| arginine repressor [Salmonella enterica subsp. enterica serovar Typhi s... gi\|16762119 - gi\|16762119\|ref\|NP_457736.1\| arginine repressor [Salmonella enterica subsp. enterica serovar Typhi s... gi\|213622196 - gi\|213622196\|ref\|ZP_03374979.1\| arginine repressor [Salmonella enterica subsp. enterica serovar Typh... gi\|213583122 - gi\|213583122\|ref\|ZP_03364948.1\| arginine repressor [Salmonella enterica subsp. enterica serovar Typh... ARGR_SALPA - Arginine repressor OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=argR PE=3 SV=1 gi\|214000998 - gi\|214000998\|ref\|ZP_03411733.1\| arginine repressor [Salmonella enterica subsp. enterica serovar Typh... ARGR_SALCH - Arginine repressor OS=Salmonella choleraesuis (strain SC-B67) GN=argR PE=3 SV=1 gi\|213646649 - gi\|213646649\|ref\|ZP_03376702.1\| arginine repressor [Salmonella enterica subsp. enterica serovar Typh... ARGR_SALTY - Arginine repressor OS=Salmonella typhimurium GN=argR PE=1 SV=1 lcl\|NC_016856.1_... - [gene=argR] [protein=arginine repressor] [protein_id=YP_005239546.1] [location=3541927..3542397] ARGR_SALCH - Arginine repressor OS=Salmonella choleraesuis GN=argR PE=3 SV=1 ARGR_SALTI - Arginine repressor OS=Salmonella typhi GN=argR PE=3 SV=1 ARGR_SALTI - Arginine repressor OS=Salmonella typhi GN=argR PE=3 SV=1	201.0	[0..1]	[156..1]
ARGR_PECAS - Arginine repressor OS=Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) GN=argR PE=3 SV=... ARGR_ERWCT - Arginine repressor OS=Erwinia carotovora subsp. atroseptica GN=argR PE=3 SV=1	200.0	[0..1]	[156..1]
ARGR_VIBVY - Arginine repressor OS=Vibrio vulnificus (strain YJ016) GN=argR PE=1 SV=1 ARGR_VIBVU - Arginine repressor OS=Vibrio vulnificus (strain CMCP6) GN=argR PE=3 SV=1 ARGR_VIBVU - Arginine repressor OS=Vibrio vulnificus GN=argR PE=3 SV=1	200.0	[0..1]	[153..1]
gi\|109389834 - gi\|109389834\|gb\|ABG29646.1\| arginine biosynthesis repressor [Escherichia coli] gi\|253975075, gi... - gi\|254163174\|ref\|YP_003046282.1\| arginine repressor [Escherichia coli B str. REL606], gi\|253975075\|g... gi\|242378775, gi... - gi\|251786502\|ref\|YP_003000806.1\| hypothetical protein B21_03048 [Escherichia coli BL21], gi\|24237877... gi\|253979231, gi... - gi\|254289924\|ref\|YP_003055672.1\| arginine repressor [Escherichia coli BL21(DE3)], gi\|253979231\|gb\|AC...	199.0	[0..1]	[156..1]
gi\|116184028, gi... - gi\|75854581\|ref\|ZP_00762267.1\| COG1438: Arginine repressor [Vibrio sp. Ex25], gi\|116184028\|ref\|ZP_01...	199.0	[0..1]	[153..1]
gi\|238783535, gi... - gi\|77958771\|ref\|ZP_00822799.1\| COG1438: Arginine repressor [Yersinia bercovieri ATCC 43970], gi\|2387... gi\|238787574, gi... - gi\|77973998\|ref\|ZP_00829541.1\| COG1438: Arginine repressor [Yersinia frederiksenii ATCC 33641], gi\|2... gi\|238711650, gi... - gi\|238750106\|ref\|ZP_04611609.1\| Arginine repressor [Yersinia rohdei ATCC 43380], gi\|238711650\|gb\|EEQ...	199.0	[0..1]	[156..1]
gi\|84394040, gi\|... - gi\|84394040\|ref\|ZP_00992777.1\| arginine repressor [Vibrio splendidus 12B01], gi\|84375326\|gb\|EAP92236... gi\|86147823, gi\|... - gi\|86147823\|ref\|ZP_01066129.1\| arginine repressor [Vibrio sp. MED222], gi\|85834350\|gb\|EAQ52502.1\| ar... ARGR_VIBTL - Arginine repressor OS=Vibrio tasmaniensis (strain LGP32) GN=argR PE=3 SV=1	199.0	[0..1]	[153..1]

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Predicted Domain #1

Region A:
Residues: [1-74]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRSSAKQEEL VKAFKALLKE EKFSSQGEIV AALQEQGFDN INQSKVSRML TKFGAVRTRN  60
   61 AKMEMVYCLP AELG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	24.0
Match:	1aoyA
Description:	N-TERMINAL DOMAIN OF ESCHERICHIA COLI ARGININE REPRESSOR NMR, 23 STRUCTURES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	3.98990675336286	bayes_pls_golite062009
DNA binding	3.4273272886116	bayes_pls_golite062009
nucleic acid binding	3.38054693035398	bayes_pls_golite062009
transcription factor activity	2.80110428028438	bayes_pls_golite062009
binding	2.18911933843505	bayes_pls_golite062009
transcription activator activity	0.53294679084865	bayes_pls_golite062009
sequence-specific DNA binding	0.53285802828572	bayes_pls_golite062009
transcription repressor activity	0.513853050429619	bayes_pls_golite062009
protein binding	0.035220363090062	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [75-156]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VPTTSSPLKN LVLDIDYNDA VVVIHTSPGA AQLIARLLDS LGKAEGILGT IAGDDTIFTT  60
   61 PANGFTVKDL YEAILELFDQ EL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	21.69897
Match:	1xxaA
Description:	C-terminal domain of arginine repressor
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: