YRC Public Data Repository - Protein Structure Prediction

Protein:	ARAF_ECOLI
Organism:	Escherichia coli
Length:	329 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ARAF_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|167038831, gi... - gi\|167038831\|ref\|YP_001661816.1\| periplasmic binding protein/LacI transcriptional regulator [Thermoa... gi\|242258204, gi... - gi\|242258204\|ref\|ZP_04803030.1\| transcriptional regulator, LacI family [Thermoanaerobacter sp. X513]...	275.0	[0..2]	[320..36]
gi\|20515183, gi\|... - gi\|20806727\|ref\|NP_621898.1\| transcriptional regulator [Thermoanaerobacter tengcongensis MB4], gi\|20... gi\|20806727 - gi\|20806727\|ref\|NP_621898.1\| Transcriptional regulator [Thermoanaerobacter tengcongensis MB4] gi\|254478068, gi... - gi\|254478068\|ref\|ZP_05091451.1\| Periplasmic binding proteins and sugar binding domain of the LacI fa...	274.0	[0..3]	[321..37]
gi\|51891908, gi\|... - gi\|51891908\|ref\|YP_074599.1\| LacI family transcriptional repressor [Symbiobacterium thermophilum IAM...	270.0	[0..3]	[319..34]
gi\|76797419, gi\|... - gi\|76797419\|ref\|ZP_00779738.1\| regulatory protein, LacI:Periplasmic binding protein/LacI transcripti... gi\|241882990, gi... - gi\|241904637\|ref\|ZP_04789316.1\| transcriptional regulator, LacI family [Thermoanaerobacter brockii s...	270.0	[0..2]	[320..36]
gi\|89209818, gi\|... - gi\|89209818\|ref\|ZP_01188212.1\| regulatory protein, LacI:Periplasmic binding protein/LacI transcripti...	266.0	[0..3]	[318..36]
gi\|90410173, gi\|... - gi\|90410173\|ref\|ZP_01218190.1\| Putative ribose operon repressor, rbsR [Photobacterium profundum 3TCK...	263.0	[0..3]	[319..35]
gi\|46916658, gi\|... - gi\|54303230\|ref\|YP_133223.1\| putative ribose operon repressor, rbsR [Photobacterium profundum SS9], ...	261.0	[0..3]	[319..35]

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Predicted Domain #1

Region A:
Residues: [1-329]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHKFTKALAA IGLAAVMSQS AMAENLKLGF LVKQPEEPWF QTEWKFADKA GKDLGFEVIK  60
   61 IAVPDGEKTL NAIDSLAASG AKGFVICTPD PKLGSAIVAK ARGYDMKVIA VDDQFVNAKG 120
  121 KPMDTVPLVM MAATKIGERQ GQELYKEMQK RGWDVKESAV MAITANELDT ARRRTTGSMD 180
  181 ALKAAGFPEK QIYQVPTKSN DIPGAFDAAN SMLVQHPEVK HWLIVGMNDS TVLGGVRATE 240
  241 GQGFKAADII GIGINGVDAV SELSKAQATG FYGSLLPSPD VHGYKSSEML YNWVAKDVEP 300
  301 PKFTEVTDVV LITRDNFKEE LEKKGLGGK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	46.39794
Match:	1abeA
Description:	NOVEL STEREOSPECIFICITY OF THE L-ARABINOSE-BINDING PROTEIN
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.22720925836419	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: