YRC Public Data Repository - Protein Structure Prediction

Protein:	ALLC_ECOLI
Organism:	Escherichia coli
Length:	411 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ALLC_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|68345339, gi\|... - gi\|70731040\|ref\|YP_260781.1\| allantoate amidohydrolase [Pseudomonas fluorescens Pf-5], gi\|68345339\|g...	302.0	[0..4]	[409..18]
gi\|23501186, gi\|... - gi\|23501186\|ref\|NP_697313.1\| allantoate amidohydrolase [Brucella suis 1330], gi\|23347064\|gb\|AAN29228...	300.0	[0..2]	[409..7]
gi\|71148151, gi\|... - gi\|71282411\|ref\|YP_270699.1\| allantoate amidohydrolase [Colwellia psychrerythraea 34H], gi\|71148151\|...	300.0	[0..3]	[409..5]
gi\|78696156, gi\|... - gi\|78696156\|ref\|ZP_00860666.1\| Amidase, hydantoinase/carbamoylase [Bradyrhizobium sp. BTAi1], gi\|785...	299.0	[0..2]	[410..16]
gi\|77459661, gi\|... - gi\|77459661\|ref\|YP_349168.1\| allantoate amidohydrolase [Pseudomonas fluorescens Pf0-1], gi\|77383664\|...	298.0	[0..4]	[402..15]
gi\|254709443 - gi\|254709443\|ref\|ZP_05171254.1\| allantoate amidohydrolase [Brucella pinnipedialis B2/94] gi\|254713138 - gi\|254713138\|ref\|ZP_05174949.1\| allantoate amidohydrolase [Brucella ceti M644/93/1] gi\|254701099 - gi\|254701099\|ref\|ZP_05162927.1\| allantoate amidohydrolase [Brucella suis bv. 5 str. 513] gi\|254707977 - gi\|254707977\|ref\|ZP_05169805.1\| allantoate amidohydrolase [Brucella pinnipedialis M163/99/10] gi\|189023528, gi... - gi\|189023528\|ref\|YP_001934296.1\| Peptidase M20/M25/M40 [Brucella abortus S19], gi\|189019100\|gb\|ACD71... gi\|254716508 - gi\|254716508\|ref\|ZP_05178319.1\| allantoate amidohydrolase [Brucella ceti M13/05/1] gi\|254729626 - gi\|254729626\|ref\|ZP_05188204.1\| allantoate amidohydrolase [Brucella abortus bv. 4 str. 292] gi\|82699205 - gi\|82699205\|ref\|YP_413779.1\| allantoate amidohydrolase [Brucella melitensis biovar Abortus 2308] gi\|82615306 - gi\|82615306\|emb\|CAJ10266.1\| Peptidase M20/M25/M40 [Brucella melitensis biovar Abortus 2308] gi\|225618463, gi... - gi\|225626806\|ref\|ZP_03784845.1\| amidase, hydantoinase/carbamoylase family protein [Brucella ceti str... gi\|254693075 - gi\|254693075\|ref\|ZP_05154903.1\| allantoate amidohydrolase [Brucella abortus bv. 3 str. Tulya] gi\|254696716 - gi\|254696716\|ref\|ZP_05158544.1\| allantoate amidohydrolase [Brucella abortus bv. 2 str. 86/8/59] gi\|237814765, gi... - gi\|237814765\|ref\|ZP_04593763.1\| amidase, hydantoinase/carbamoylase family [Brucella abortus str. 230... gi\|254688593 - gi\|254688593\|ref\|ZP_05151847.1\| allantoate amidohydrolase [Brucella abortus bv. 6 str. 870]	297.0	[0..2]	[409..7]
gi\|225640192, gi... - gi\|225851827\|ref\|YP_002732060.1\| amidase, hydantoinase/carbamoylase family protein [Brucella meliten... gi\|25290174 - pir\|\|AE3457 N-carbamoyl-L-amino acid amidohydrolase (EC 3.5.1.-) [imported] - Brucella melitensis (s... gi\|17987926, gi\|... - gi\|17987926\|ref\|NP_540560.1\| allantoate amidohydrolase [Brucella melitensis 16M], gi\|17983664\|gb\|AAL...	297.0	[0..2]	[409..7]
gi\|11350628 - pir\|\|C83591 N-carbamoyl-beta-alanine amidohydrolase PA0444 [imported] - Pseudomonas aeruginosa (stra... gi\|116054174, gi... - gi\|53727148\|ref\|ZP_00140894.2\| COG0624: Acetylornithine deacetylase/Succinyl-diaminopimelate desucci... gi\|107099429 - gi\|107099429\|ref\|ZP_01363347.1\| hypothetical protein PaerPA_01000441 [Pseudomonas aeruginosa PACS2] gi\|9946302, gi\|1... - gi\|9946302\|gb\|AAG03833.1\|AE004481_9 N-carbamoyl-beta-alanine amidohydrolase [Pseudomonas aeruginosa ... gi\|194554527, gi... - gi\|84324323\|ref\|ZP_00972382.1\| COG0624: Acetylornithine deacetylase/Succinyl-diaminopimelate desucci...	297.0	[0..4]	[410..15]
gi\|254237324, gi... - gi\|84318637\|ref\|ZP_00967058.1\| COG0624: Acetylornithine deacetylase/Succinyl-diaminopimelate desucci...	297.0	[0..4]	[410..15]
gi\|111282757, gi... - gi\|111616823\|ref\|ZP_01403854.1\| Amidase, hydantoinase/carbamoylase [Acidovorax avenae subsp. citrull...	296.0	[0..2]	[408..50]

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Predicted Domain #1

Region A:
Residues: [1-411]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MITHFRQAIE ETLPWLSSFG ADPAGGMTRL LYSPEWLETQ QQFKKRMAAS GLETRFDEVG  60
   61 NLYGRLNGTE YPQEVVLSGS HIDTVVNGGN LDGQFGALAA WLAIDWLKTQ YGAPLRTVEV 120
  121 VAMAEEEGSR FPYVFWGSKN IFGLANPDDV RNICDAKGNS FVDAMKACGF TLPNAPLTPR 180
  181 QDIKAFVELH IEQGCVLESN GQSIGVVNAI VGQRRYTVTL NGESNHAGTT PMGYRRDTVY 240
  241 AFSRICHQSV EKAKRMGDPL VLTFGKVEPR PNTVNVVPGK TTFTIDCRHT DAAVLRDFTQ 300
  301 QLENDMRAIC DEMDIGIDID LWMDEEPVPM NKELVATLTE LCEREKLNYR VMHSGAGHDA 360
  361 QIFAPRVPTC MIFIPSINGI SHNPAERTNI TDLAEGVKTL ALMLYQLAWQ K

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	72.69897
Match:	1z2lA
Description:	Crystal structure of Allantoate-amidohydrolase from E.coli K12 in complex with substrate Allantoate
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrolase activity	3.0609849976664	bayes_pls_golite062009
peptidase activity	3.04706302825019	bayes_pls_golite062009
catalytic activity	2.3710874246093	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	2.30644893326426	bayes_pls_golite062009
exopeptidase activity	1.25673143627992	bayes_pls_golite062009
succinyl-diaminopimelate desuccinylase activity	0.851637991746991	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	0.818684394421989	bayes_pls_golite062009
carboxypeptidase activity	0.76593160329727	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: