YRC Public Data Repository - Protein Structure Prediction

Protein:	ALLA_ECOLI
Organism:	Escherichia coli
Length:	160 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ALLA_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|25353293, gi\|... - pir\|\|F90699 ureidoglycolate hydrolase [imported] - Escherichia coli (strain O157:H7, substrain RIMD... ALLA_SHIFL - Ureidoglycolate lyase OS=Shigella flexneri GN=allA PE=1 SV=1 gi\|242376284, gi... - gi\|251784011\|ref\|YP_002998315.1\| hypothetical protein B21_00460 [Escherichia coli BL21], gi\|24237628... gi\|30040241, gi\|... - gi\|30061997\|ref\|NP_836168.1\| ureidoglycolate hydrolase [Shigella flexneri 2a str. 2457T], gi\|3004024... gi\|253774506, gi... - gi\|254287377\|ref\|YP_003053125.1\| ureidoglycolate hydrolase [Escherichia coli BL21(DE3)], gi\|25397668... ALLA_ECO57 - Ureidoglycolate lyase OS=Escherichia coli O157:H7 GN=allA PE=1 SV=1 gi\|24111881, gi\|... - gi\|24111881\|ref\|NP_706391.1\| ureidoglycolate hydrolase [Shigella flexneri 2a str. 301], gi\|24050681\|... gi\|253972474, gi... - gi\|254160573\|ref\|YP_003043681.1\| ureidoglycolate hydrolase [Escherichia coli B str. REL606], gi\|2539... gi\|254591095, gi... - gi\|254791695\|ref\|YP_003076532.1\| ureidoglycolate hydrolase [Escherichia coli O157:H7 str. TW14359], ... gi\|12513397, gi\|... - gi\|15800241\|ref\|NP_286253.1\| ureidoglycolate hydrolase [Escherichia coli O157:H7 EDL933], gi\|1251339... gi\|194423706, gi... - gi\|83587044\|ref\|ZP_00925674.1\| COG3194: Ureidoglycolate hydrolase [Escherichia coli 101-1], gi\|19443... ALLA_SHIB3 - Ureidoglycolate lyase OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=allA PE=3 SV=1 ALLA_ECOHS - Ureidoglycolate lyase OS=Escherichia coli O9:H4 (strain HS) GN=allA PE=3 SV=1 gi\|75229338 - gi\|75229338\|ref\|ZP_00715893.1\| COG3194: Ureidoglycolate hydrolase [Escherichia coli B7A] gi\|192959153, gi... - gi\|75239003\|ref\|ZP_00722985.1\| COG3194: Ureidoglycolate hydrolase [Escherichia coli E110019], gi\|193... gi\|188017664, gi... - gi\|188017664\|gb\|EDU55786.1\| ureidoglycolate hydrolase [Escherichia coli O157:H7 str. EC4113], gi\|168... gi\|188493003, gi... - gi\|75514624\|ref\|ZP_00736879.1\| COG3194: Ureidoglycolate hydrolase [Escherichia coli 53638], gi\|18849... ALLA_SHIDS - Ureidoglycolate lyase OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=allA PE=3 SV=1 gi\|168760330, gi... - gi\|189369157\|gb\|EDU87573.1\| ureidoglycolate hydrolase [Escherichia coli O157:H7 str. EC4501], gi\|168... ALLA_SHIBS - Ureidoglycolate lyase OS=Shigella boydii serotype 4 (strain Sb227) GN=allA PE=3 SV=1 gi\|168754619, gi... - gi\|189358070\|gb\|EDU76489.1\| ureidoglycolate hydrolase [Escherichia coli O157:H7 str. EC4401], gi\|168... gi\|15829820, gi\|... - gi\|15829820\|ref\|NP_308593.1\| ureidoglycolate hydrolase [Escherichia coli O157:H7 str. Sakai], gi\|133... ALLA_SHIF8 - Ureidoglycolate lyase OS=Shigella flexneri serotype 5b (strain 8401) GN=allA PE=3 SV=1 gi\|194419002, gi... - gi\|83570167\|ref\|ZP_00921613.1\| COG3194: Ureidoglycolate hydrolase [Shigella dysenteriae 1012], gi\|19... ALLA_ECO5E - Ureidoglycolate lyase OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=allA PE=3 SV=1 gi\|208822890, gi... - gi\|208822890\|ref\|ZP_03263208.1\| ureidoglycolate hydrolase [Escherichia coli O157:H7 str. EC4042], gi... gi\|217324272, gi... - gi\|217324272\|ref\|ZP_03440356.1\| ureidoglycolate hydrolase [Escherichia coli O157:H7 str. TW14588], g... ALLA_ECOSE - Ureidoglycolate lyase OS=Escherichia coli (strain SE11) GN=allA PE=3 SV=1 gi\|187769695, gi... - gi\|187769695\|gb\|EDU33539.1\| ureidoglycolate hydrolase [Escherichia coli O157:H7 str. EC4196], gi\|168... gi\|189362461, gi... - gi\|189362461\|gb\|EDU80880.1\| ureidoglycolate hydrolase [Escherichia coli O157:H7 str. EC4486], gi\|168... gi\|189373573, gi... - gi\|189373573\|gb\|EDU91989.1\| ureidoglycolate hydrolase [Escherichia coli O157:H7 str. EC869], gi\|1687... gi\|189003093, gi... - gi\|189003093\|gb\|EDU72079.1\| ureidoglycolate hydrolase [Escherichia coli O157:H7 str. EC4076], gi\|168... ALLA_ECOLC - Ureidoglycolate lyase OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=allA PE=3 SV=1 gi\|195936075 - gi\|195936075\|ref\|ZP_03081457.1\| ureidoglycolate hydrolase [Escherichia coli O157:H7 str. EC4024] gi\|189379285, gi... - gi\|189379285\|gb\|EDU97701.1\| ureidoglycolate hydrolase [Escherichia coli O157:H7 str. EC508], gi\|1687... gi\|208732389, gi... - gi\|208815741\|ref\|ZP_03256920.1\| ureidoglycolate hydrolase [Escherichia coli O157:H7 str. EC4045], gi... gi\|208727950, gi... - gi\|208808149\|ref\|ZP_03250486.1\| ureidoglycolate hydrolase [Escherichia coli O157:H7 str. EC4206], gi... gi\|124529315, gi... - gi\|124529315\|ref\|ZP_01700349.1\| Ureidoglycolate hydrolase [Escherichia coli B], gi\|124499915\|gb\|EAY4...	239.0	[0..1]	[160..1]
ALLA_ECOUT - Ureidoglycolate lyase OS=Escherichia coli (strain UTI89 / UPEC) GN=allA PE=3 SV=1 ALLA_ECOL5 - Ureidoglycolate lyase OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=allA PE=3 SV=1 ALLA_ECOK1 - Ureidoglycolate lyase OS=Escherichia coli O1:K1 / APEC GN=allA PE=3 SV=1 ALLA_ECO81 - Ureidoglycolate lyase OS=Escherichia coli O81 (strain ED1a) GN=allA PE=3 SV=1 ALLA_ECO45 - Ureidoglycolate lyase OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=allA PE=3 SV=1 ALLA_ECO27 - Ureidoglycolate lyase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=allA PE=3 SV=1 sp\|B7UKI3\|ALLA_ECO27 - Ureidoglycolate hydrolase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=allA PE=3 SV=1 gi\|190907365, gi... - gi\|75240699\|ref\|ZP_00724606.1\| COG3194: Ureidoglycolate hydrolase [Escherichia coli F11], gi\|1911722... ALLA_ECOLU - Ureidoglycolate lyase OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) GN=allA PE=3 SV=1	239.0	[0..1]	[160..1]
gi\|75257854, gi\|... - gi\|75257854\|ref\|ZP_00729332.1\| COG3194: Ureidoglycolate hydrolase [Escherichia coli E22], gi\|1930641... ALLA_ECO8A - Ureidoglycolate lyase OS=Escherichia coli O8 (strain IAI1) GN=allA PE=3 SV=1 gi\|75209190, gi\|... - gi\|75209190\|ref\|ZP_00709441.1\| COG3194: Ureidoglycolate hydrolase [Escherichia coli B171], gi\|194429... ALLA_ECO55 - Ureidoglycolate lyase OS=Escherichia coli (strain 55989 / EAEC) GN=allA PE=3 SV=1 ALLA_ECO24 - Ureidoglycolate lyase OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=allA PE=3 SV=1	239.0	[0..1]	[160..1]
ALLA_ECOL6 - Ureidoglycolate lyase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=allA PE=3 SV... ALLA_ECOL6 - Ureidoglycolate hydrolase OS=Escherichia coli O6 GN=allA PE=3 SV=1 gi\|227838572, gi... - gi\|227884486\|ref\|ZP_04002291.1\| ureidoglycolate hydrolase [Escherichia coli 83972], gi\|227838572\|gb\|...	237.0	[0..1]	[160..1]
gi\|74019843, gi\|... - gi\|74019843\|ref\|ZP_00690455.1\| Ureidoglycolate hydrolase [Burkholderia ambifaria AMMD], gi\|72607488\|...	234.0	[0..2]	[154..3]
ALLA_PSEA7 - Ureidoglycolate lyase OS=Pseudomonas aeruginosa (strain PA7) GN=allA PE=3 SV=1	234.0	[0..2]	[156..3]
gi\|82407523, gi\|... - gi\|82407524\|pdb\|1YQC\|B Chain B, Crystal Structure Of Ureidoglycolate Hydrolase (Alla) From Escherich...	234.0	[0..2]	[160..2]
gi\|56554717, gi\|... - gi\|56554718\|pdb\|1XSR\|B Chain B, X-Ray Structure Of Northeast Structural Genomics Consortium Target S...	234.0	[0..2]	[160..2]
ALLA_PSEE4 - Ureidoglycolate lyase OS=Pseudomonas entomophila (strain L48) GN=allA PE=3 SV=1 gi\|95109828 - gi\|95109828\|emb\|CAK14533.1\| Ureidoglycolate hydrolase [Pseudomonas entomophila L48]	233.0	[0..2]	[158..3]
ALLA_PSEAB - Ureidoglycolate lyase OS=Pseudomonas aeruginosa (strain UCBPP-PA14) GN=allA PE=3 SV=1 ALLA_PSEA8 - Ureidoglycolate lyase OS=Pseudomonas aeruginosa (strain LESB58) GN=allA PE=3 SV=1 ALLA_PSEAE - Ureidoglycolate lyase OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228... gi\|254239863, gi... - gi\|84328428\|ref\|ZP_00976435.1\| COG3194: Ureidoglycolate hydrolase [Pseudomonas aeruginosa 2192], gi\|... gi\|126166541, gi... - gi\|84321700\|ref\|ZP_00970054.1\| COG3194: Ureidoglycolate hydrolase [Pseudomonas aeruginosa C3719], gi... ALLA_PSEAE - Ureidoglycolate hydrolase OS=Pseudomonas aeruginosa GN=allA PE=3 SV=1	233.0	[0..2]	[156..3]

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Predicted Domain #1

Region A:
Residues: [1-160]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLQVLPLSQ EAFSAYGDVI ETQQRDFFHI NNGLVERYHD LALVEILEQD CTLISINRAQ  60
   61 PANLPLTIHE LERHPLGTQA FIPMKGEVFV VVVALGDDKP DLSTLRAFIT NGEQGVNYHR 120
  121 NVWHHPLFAW QRVTDFLTID RGGSDNCDVE SIPEQELCFA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	63.69897
Match:	1yqcA
Description:	Crystal Structure of Ureidoglycolate Hydrolase (AllA) from Escherichia coli O157:H7
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ureidoglycolate hydrolase activity	2.63080015873229	bayes_pls_golite062009
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	1.64225826538892	bayes_pls_golite062009
dioxygenase activity	0.930778069601015	bayes_pls_golite062009
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	0.901194069960417	bayes_pls_golite062009
binding	0.797072992275176	bayes_pls_golite062009
nucleic acid binding	0.623892372229422	bayes_pls_golite062009
DNA binding	0.483453407263708	bayes_pls_golite062009
transcription regulator activity	0.465649136635506	bayes_pls_golite062009
catalytic activity	0.401988496917198	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: